DK119285A - Benzothiazol- og benzothiophenderivater - Google Patents
Benzothiazol- og benzothiophenderivater Download PDFInfo
- Publication number
- DK119285A DK119285A DK119285A DK119285A DK119285A DK 119285 A DK119285 A DK 119285A DK 119285 A DK119285 A DK 119285A DK 119285 A DK119285 A DK 119285A DK 119285 A DK119285 A DK 119285A
- Authority
- DK
- Denmark
- Prior art keywords
- benzothiophender
- benzothiazol
- derivatives
- benzothiophender derivatives
- Prior art date
Links
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical compound C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848406906A GB8406906D0 (en) | 1984-03-16 | 1984-03-16 | Benzo-thiazole and benzothiophene derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK119285D0 DK119285D0 (da) | 1985-03-15 |
| DK119285A true DK119285A (da) | 1985-09-17 |
Family
ID=10558202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK119285A DK119285A (da) | 1984-03-16 | 1985-03-15 | Benzothiazol- og benzothiophenderivater |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US4665206A (fr) |
| EP (1) | EP0158380B1 (fr) |
| JP (1) | JPS60209577A (fr) |
| KR (1) | KR870000920B1 (fr) |
| AU (1) | AU568428B2 (fr) |
| CA (1) | CA1254216A (fr) |
| DE (1) | DE3567459D1 (fr) |
| DK (1) | DK119285A (fr) |
| ES (4) | ES8707223A1 (fr) |
| FI (1) | FI80883C (fr) |
| GB (1) | GB8406906D0 (fr) |
| HU (1) | HU198030B (fr) |
| IE (1) | IE57977B1 (fr) |
| ZA (1) | ZA851807B (fr) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58555B1 (en) * | 1984-12-10 | 1993-10-06 | Warner Almbert Company | Novel benzothiophenes and benzofurans having antiallergy activity |
| EP0253650A3 (fr) * | 1986-07-18 | 1989-09-13 | Eli Lilly And Company | Dérivés du benzothiophène |
| US4873259A (en) * | 1987-06-10 | 1989-10-10 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
| US4822809A (en) * | 1987-11-13 | 1989-04-18 | Abbott Laboratories | Benzazole lipoxygenase inhibiting compounds |
| US4882354A (en) * | 1987-12-16 | 1989-11-21 | Norwich Eaton Pharmaceuticals, Inc. | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents |
| DE68901424D1 (de) * | 1988-07-05 | 1992-06-11 | Akzo Nv | Verbindungen mit bronchodilatatorischer aktivitaet. |
| IE913683A1 (en) * | 1990-10-26 | 1992-05-22 | Akzo Nv | USE OF A BENZO[b]THIOPHENE-2-CARBOXIMIDAMIDE DERIVATIVE |
| US5276052A (en) * | 1990-10-26 | 1994-01-04 | Akzo N.V. | Use of a benzo[b]thiopene-2-carboximidamide derivative |
| DE4128871A1 (de) * | 1991-08-30 | 1993-03-04 | Boehringer Mannheim Gmbh | Benzo(b)thiophenderivate, verfahren zu ihrer herstellung und arzneimittel |
| US5340833A (en) * | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
| US5436246A (en) * | 1992-09-17 | 1995-07-25 | Merrell Dow Pharmaceuticals Inc. | Serotonin receptor agents |
| CN1073563C (zh) * | 1994-04-11 | 2001-10-24 | 中外制药株式会社 | 4,6－二叔丁基－2,3－二氢苯并噻吩衍生物 |
| US5703116A (en) * | 1995-04-18 | 1997-12-30 | Geron Corporation | Telomerase Inhibitors |
| US5863936A (en) * | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
| US5760062A (en) * | 1995-04-18 | 1998-06-02 | Geron Corporation | Telomerase inhibitors |
| US5656638A (en) * | 1995-04-18 | 1997-08-12 | Geron Corporation | Telomerase inhibitors |
| US5770613A (en) * | 1995-09-29 | 1998-06-23 | Geron Corporation | Telomerase inhibitors |
| US5767278A (en) * | 1995-10-06 | 1998-06-16 | Geron Corporation | Telomerase inhibitors |
| US6362216B1 (en) | 1998-10-27 | 2002-03-26 | Array Biopharma Inc. | Compounds which inhibit tryptase activity |
| MXPA02001830A (es) | 1999-08-21 | 2002-08-12 | Byk Gulden Lomberg Chem Fab | Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor. |
| ES2427930T3 (es) | 2001-05-23 | 2013-11-04 | Mitsubishi Tanabe Pharma Corporation | Composición terapéutica para el tratamiento regenerativo de enfermedades de los cartílagos |
| JP4510384B2 (ja) | 2001-05-23 | 2010-07-21 | 田辺三菱製薬株式会社 | 骨折治癒促進用組成物 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EA200501548A1 (ru) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | Ингибиторы фосфодиэстераз при бесплодии |
| US7935724B2 (en) | 2003-10-09 | 2011-05-03 | Merck Hdac Research, Llc | Thiophene and benzothiophene hydroxamic acid derivatives |
| WO2006101454A1 (fr) * | 2005-03-21 | 2006-09-28 | S*Bio Pte Ltd | Derives du benzothiophene: preparation et applications pharmaceutiques |
| MY148644A (en) * | 2005-07-18 | 2013-05-15 | Orion Corp | New pharmaceutical compounds |
| CA2643012A1 (fr) * | 2006-02-21 | 2007-08-30 | Trigen Limited | Composes heterocycliques et leur utilisation dans le traitement des maladies cardiovasculaires |
| CA2674237C (fr) | 2006-12-28 | 2015-11-24 | Rigel Pharmaceuticals, Inc. | Composes d'heterocycloalkyloxybenzamide n-substitues, et procedes d'utilisation |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EP3241839B1 (fr) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012118972A2 (fr) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Procédé de préparation d'agonistes du guanylate cyclase c |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| WO2014151206A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
| CN105979959B (zh) | 2013-08-09 | 2021-11-30 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
| WO2020237096A1 (fr) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combinaison pour baisser le phosphate sérique chez un patient |
| CN111296447B (zh) * | 2020-03-24 | 2021-09-17 | 东营施普瑞石油工程技术有限公司 | 一种油田用杀菌剂及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB438211A (en) * | 1934-06-01 | 1935-11-13 | Ig Farbenindustrie Ag | The manufacture of heterocyclic compounds |
| US2775593A (en) * | 1948-10-01 | 1956-12-25 | Schenley Ind Inc | Thiosemicarbazones of aldehydes and ketones of the heterocyclic series |
| GB1231170A (fr) * | 1967-12-15 | 1971-05-12 | ||
| BE759237A (fr) * | 1969-11-21 | 1971-05-01 | Montedison Spa | Procede de preparation d'amides a partir de composes heterocycliques azotes |
| BE786520A (fr) * | 1971-07-23 | 1973-01-22 | Bayer Ag | Nouveaux benzothiazoles substitues, leur preparation et leur application comme fongicides et bactericides |
| DE2258036A1 (de) * | 1972-11-27 | 1974-05-30 | Goedecke Ag | Verfahren zur herstellung von benzo eckige klammer auf b eckige klammer zu thiophen-derivaten |
| FR2305982A1 (fr) * | 1975-04-03 | 1976-10-29 | Innothera Lab Sa | Nouvelles benzothienyl amino (propyl et butyl) cetones, leur procede de preparation et leur application en therapeutique |
| DK351778A (da) * | 1977-08-15 | 1979-02-16 | Lilly Co Eli | Thiadiazolylbenzamider og fremgangsmaade til deres fremstilling |
| US4140785A (en) * | 1978-05-08 | 1979-02-20 | E. I. Du Pont De Nemours And Company | N-(benzothienopyrazol)amide antirhinoviral agents |
| JPS5936670A (ja) * | 1982-08-25 | 1984-02-28 | Takeda Chem Ind Ltd | ベンゾチアゾ−ル誘導体，その製造法およびそれを含有する摂食抑制剤 |
-
1984
- 1984-03-16 GB GB848406906A patent/GB8406906D0/en active Pending
-
1985
- 1985-03-06 EP EP85200325A patent/EP0158380B1/fr not_active Expired
- 1985-03-06 DE DE8585200325T patent/DE3567459D1/de not_active Expired
- 1985-03-07 US US06/709,396 patent/US4665206A/en not_active Expired - Fee Related
- 1985-03-07 IE IE592/85A patent/IE57977B1/en not_active IP Right Cessation
- 1985-03-11 CA CA000476161A patent/CA1254216A/fr not_active Expired
- 1985-03-11 ZA ZA851807A patent/ZA851807B/xx unknown
- 1985-03-14 AU AU39852/85A patent/AU568428B2/en not_active Ceased
- 1985-03-15 JP JP60052167A patent/JPS60209577A/ja active Granted
- 1985-03-15 FI FI851038A patent/FI80883C/fi not_active IP Right Cessation
- 1985-03-15 ES ES541336A patent/ES8707223A1/es not_active Expired
- 1985-03-15 HU HU85968A patent/HU198030B/hu not_active IP Right Cessation
- 1985-03-15 DK DK119285A patent/DK119285A/da not_active Application Discontinuation
- 1985-03-16 KR KR1019850001704A patent/KR870000920B1/ko not_active IP Right Cessation
-
1986
- 1986-01-27 ES ES551282A patent/ES8704924A1/es not_active Expired
- 1986-01-27 ES ES551280A patent/ES8704925A1/es not_active Expired
- 1986-01-27 ES ES551281A patent/ES8704926A1/es not_active Expired
-
1989
- 1989-04-06 US US07/333,806 patent/US4929636A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR850006391A (ko) | 1985-10-05 |
| ES8704926A1 (es) | 1987-04-16 |
| EP0158380A1 (fr) | 1985-10-16 |
| FI851038L (fi) | 1985-09-17 |
| KR870000920B1 (ko) | 1987-05-07 |
| HU198030B (en) | 1989-07-28 |
| DE3567459D1 (en) | 1989-02-16 |
| IE850592L (en) | 1985-09-16 |
| ES8707223A1 (es) | 1987-07-16 |
| ES551281A0 (es) | 1987-04-16 |
| FI851038A0 (fi) | 1985-03-15 |
| CA1254216A (fr) | 1989-05-16 |
| AU568428B2 (en) | 1987-12-24 |
| ES551280A0 (es) | 1987-04-16 |
| AU3985285A (en) | 1985-09-19 |
| US4929636A (en) | 1990-05-29 |
| ES551282A0 (es) | 1987-04-16 |
| IE57977B1 (en) | 1993-06-02 |
| US4665206A (en) | 1987-05-12 |
| JPS60209577A (ja) | 1985-10-22 |
| DK119285D0 (da) | 1985-03-15 |
| HUT37410A (en) | 1985-12-28 |
| EP0158380B1 (fr) | 1989-01-11 |
| FI80883B (fi) | 1990-04-30 |
| ZA851807B (en) | 1985-10-30 |
| JPH0588232B2 (fr) | 1993-12-21 |
| FI80883C (fi) | 1990-08-10 |
| ES8704924A1 (es) | 1987-04-16 |
| ES8704925A1 (es) | 1987-04-16 |
| ES541336A0 (es) | 1987-07-16 |
| GB8406906D0 (en) | 1984-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK119285A (da) | Benzothiazol- og benzothiophenderivater | |
| DK268285A (da) | Dialkoxypyridinderivater | |
| DK35785A (da) | Tetrahydrocarbazolonderivater | |
| NL940006I1 (nl) | 1,2-Benzisoxyzol-3-yl- en 1,2-benzisothiazol-3-yl-derivaten | |
| DK243985A (da) | Aminoalkylphenoxyderivater | |
| DE3463503D1 (de) | Sulfonamido-benzamide derivatives | |
| AT384066B (de) | Scharnier | |
| DK254488A (da) | Azaindol- og indolizinderivater | |
| DE3566887D1 (de) | Flavanon derivatives | |
| AT383643B (de) | Scharnier | |
| DK524585D0 (da) | Cholecalciferolderivater | |
| AT381136B (de) | Scharnier | |
| DK139286A (da) | Inden- og naphthalenderivater | |
| DK443685A (da) | Pirimidinderivater | |
| ATA333684A (de) | Scharnier | |
| DK320585A (da) | Fluorallylaminderivater | |
| NO854968L (no) | Alkosymetyleter- og alkoksymetylesterderivater. | |
| DK514585A (da) | Aminoethylanilinderivater | |
| DK488185A (da) | N6-benzopyrano- og benzothiopyranoadenosiner | |
| DE3565100D1 (de) | Cycloalkane-indene-carboximidamide derivatives | |
| DK267190D0 (da) | 13-substitueret-5-ketomilbemycinderivater | |
| DK54085D0 (da) | Phenylpropargylaminderivater | |
| DE3564269D1 (de) | Eburnane derivatives | |
| AT384067B (de) | Scharnier | |
| NO892248L (no) | Alkoksymetyleter- og alkoksymetylesterderivater. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |