DK1189660T3 - Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf - Google Patents

Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf

Info

Publication number
DK1189660T3
DK1189660T3 DK00939765T DK00939765T DK1189660T3 DK 1189660 T3 DK1189660 T3 DK 1189660T3 DK 00939765 T DK00939765 T DK 00939765T DK 00939765 T DK00939765 T DK 00939765T DK 1189660 T3 DK1189660 T3 DK 1189660T3
Authority
DK
Denmark
Prior art keywords
microperforating
thin
film
making
interface devices
Prior art date
Application number
DK00939765T
Other languages
Danish (da)
English (en)
Inventor
Jonathan Eppstein
Michael R Hatch
Joseph Papp
Original Assignee
Altea Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altea Therapeutics Corp filed Critical Altea Therapeutics Corp
Application granted granted Critical
Publication of DK1189660T3 publication Critical patent/DK1189660T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M2005/3022—Worn on the body, e.g. as patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK00939765T 1999-06-08 2000-06-08 Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf DK1189660T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13805099P 1999-06-08 1999-06-08

Publications (1)

Publication Number Publication Date
DK1189660T3 true DK1189660T3 (da) 2006-08-21

Family

ID=22480210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00939765T DK1189660T3 (da) 1999-06-08 2000-06-08 Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf

Country Status (14)

Country Link
US (1) US6692456B1 (enExample)
EP (4) EP2286868A3 (enExample)
JP (3) JP4412874B2 (enExample)
CN (1) CN100402105C (enExample)
AT (1) ATE324922T1 (enExample)
AU (1) AU780752B2 (enExample)
CA (1) CA2376368C (enExample)
CY (1) CY1107518T1 (enExample)
DE (1) DE60027720T2 (enExample)
DK (1) DK1189660T3 (enExample)
ES (1) ES2260021T3 (enExample)
PT (1) PT1189660E (enExample)
WO (1) WO2000074767A2 (enExample)
ZA (1) ZA200109966B (enExample)

Families Citing this family (220)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6517532B1 (en) 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US20120150163A1 (en) * 1997-08-12 2012-06-14 Joseph Neev Home Use Device and Method for Treating Skin Conditions
PT1124607E (pt) 1998-07-14 2008-12-31 Altea Therapeutics Corp Remoção controlada de membranas biológicas por carga pirotécnica, para transporte transmembranar
US6611706B2 (en) 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6597946B2 (en) 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US20040005349A1 (en) * 2000-05-12 2004-01-08 Joseph Neev Opto-thermal material modification
AU2012201079B2 (en) * 2000-06-01 2013-03-28 Georgetown University Systems and methods for monitoring health and delivering drugs transdermally
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
WO2002015801A1 (en) * 2000-08-24 2002-02-28 Encapsulation Systems, Inc. Substance delivery system
BR0114629A (pt) * 2000-10-13 2004-01-20 Alza Corp Aparelho e método para a perfuração da pele com microprojeções
CA2433022C (en) * 2000-12-28 2016-12-06 Palomar Medical Technologies, Inc. Method and apparatus for therapeutic emr treatment of the skin
US20080214988A1 (en) * 2000-12-28 2008-09-04 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue
DE10102817B4 (de) * 2001-01-23 2006-01-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Hitzepulsgestützten transdermalen Applikation von Wirkstoffen
ES2333849T3 (es) * 2001-04-20 2010-03-02 Alza Corporation Disposicion de microsalientes que presenta un revestimiento que contiene un agente beneficioso.
US6908448B2 (en) * 2001-08-24 2005-06-21 Dermisonics, Inc. Substance delivery device
US8920375B2 (en) * 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
AU2002337788A1 (en) * 2001-09-28 2003-04-07 Biovalve Technologies, Inc. Microneedle with membrane
US6689100B2 (en) * 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US6648904B2 (en) * 2001-11-29 2003-11-18 Palomar Medical Technologies, Inc. Method and apparatus for controlling the temperature of a surface
EP1465529A4 (en) * 2002-01-15 2005-04-20 Bruce K Redding Jr PORTABLE PORTABLE ACOUSTIC APPLICATOR USED TO INDUCE THE RELEASE OF BIOACTIVE COMPOUNDS BY INTERNAL ORGANS
WO2003101507A2 (en) * 2002-03-11 2003-12-11 Altea Therapeutics Corporation Transdermal drug delivery device, method and use
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
AU2003226605A1 (en) * 2002-04-19 2003-11-03 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
BR0312430A (pt) 2002-06-19 2005-04-26 Palomar Medical Tech Inc Método e aparelho para tratamento de condições cutâneas e subcutâneas
AU2003278881A1 (en) * 2002-09-23 2004-04-08 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
US6916159B2 (en) * 2002-10-09 2005-07-12 Therasense, Inc. Device and method employing shape memory alloy
US7399401B2 (en) 2002-10-09 2008-07-15 Abbott Diabetes Care, Inc. Methods for use in assessing a flow condition of a fluid
US7431981B2 (en) * 2002-11-04 2008-10-07 The Boeing Company Polymer composite structure reinforced with shape memory alloy and method of manufacturing same
US20060184189A1 (en) † 2002-11-15 2006-08-17 Lorin Olson Cap for a dermal tissue lancing device
US20040225339A1 (en) * 2002-12-20 2004-11-11 Palomar Medical Technologies Inc. Light treatments for acne and other disorders of follicles
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
JP2006517827A (ja) * 2003-01-29 2006-08-03 イー−ピル・ファーマ・リミテッド 胃腸管内における活性薬物の送達
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
US8323955B1 (en) * 2003-03-05 2012-12-04 Sandia Corporation Micromachined patch-clamp apparatus
WO2004086947A2 (en) * 2003-03-27 2004-10-14 The General Hospital Corporation Method and apparatus for dermatological treatment and fractional skin resurfacing
ES2737835T3 (es) 2003-04-23 2020-01-16 Valeritas Inc Bomba accionada hidráulicamente para la administración de medicamentos de larga duración
GB0312552D0 (en) * 2003-06-02 2003-07-09 Nel Technologies Ltd Functional therapeutic corporeal and wound dressing heaters
IL156374A0 (en) * 2003-06-10 2004-01-04 Danenberg Holdings 2000 Ltd N Method for removing a pigmented section of skin
US20040267283A1 (en) 2003-06-25 2004-12-30 Daniela Mavor Method, device and kit for body decoration
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
IL157696A0 (en) * 2003-09-01 2004-03-28 Hawk Medical Technologies Ltd Apparatus and method for removing a pigmented section of skin
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
MXPA06006041A (es) * 2003-11-28 2007-01-31 Acrux Dds Pty Ltd Metodo y sistema para administracion transdermica rapida.
US20050228313A1 (en) * 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
US20090069741A1 (en) * 2004-04-09 2009-03-12 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery
AU2005232581A1 (en) * 2004-04-09 2005-10-27 Palomar Medical Technologies, Inc. Emr treated islets
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US9089636B2 (en) * 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
US7946984B2 (en) * 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) * 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US20060024722A1 (en) 2004-07-30 2006-02-02 Mark Fischer-Colbrie Samples for detection of oncofetal fibronectin and uses thereof
US7055756B2 (en) * 2004-10-25 2006-06-06 Lexmark International, Inc. Deposition fabrication using inkjet technology
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
US8364228B2 (en) * 2004-12-09 2013-01-29 Flexible Medical Systems, Llc Appartus and method for continuous real-time trace biomolecular sampling, analysis, and delivery
US7850645B2 (en) * 2005-02-11 2010-12-14 Boston Scientific Scimed, Inc. Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
US20060276859A1 (en) * 2005-06-02 2006-12-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Photopatterning of skin
US8157807B2 (en) * 2005-06-02 2012-04-17 The Invention Science Fund I, Llc Skin treatment including patterned light
EP1871457B1 (en) * 2005-04-11 2012-05-02 Infotonics Technology Center, Inc. Blood monitoring systems and methods thereof
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
WO2006111201A1 (en) 2005-04-18 2006-10-26 Pantec Biosolutions Ag Laser microporator
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
US20060276844A1 (en) * 2005-05-19 2006-12-07 Ruth Alon Ingestible device for nitric oxide production in tissue
US20070032846A1 (en) * 2005-08-05 2007-02-08 Bran Ferren Holographic tattoo
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
TWI419717B (zh) * 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
AU2016231468B2 (en) * 2005-06-17 2018-04-05 Passport Technologies, Inc. Permeant delivery system and methods for use thereof
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
US20070038270A1 (en) * 2005-07-05 2007-02-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step photopatterning of skin
US7942827B2 (en) * 2005-07-11 2011-05-17 Infotonics Technology Center, Inc. Minimally invasive allergy testing system
JPWO2007010900A1 (ja) * 2005-07-15 2009-01-29 Ｔｔｉ・エルビュー株式会社 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置
AU2006274530B2 (en) * 2005-08-01 2009-03-12 Hawk Medical Technologies Ltd. Eradication of pigmentation and scar tissue
US8295922B2 (en) * 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
BRPI0614556A2 (pt) * 2005-08-08 2009-08-04 Palomar Medical Tech Inc dispositivo fotocosmético seguro para os olhos
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20070048362A1 (en) * 2005-08-29 2007-03-01 Transcutaneous Technologies Inc. General purpose electrolyte solution composition for iontophoresis
US20070048340A1 (en) * 2005-08-31 2007-03-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step patterning of a skin surface
US20070088248A1 (en) * 2005-09-02 2007-04-19 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
US20100030128A1 (en) * 2005-09-06 2010-02-04 Kazuma Mitsuguchi Iontophoresis device
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
BRPI0616167A2 (pt) * 2005-09-15 2011-06-07 Palomar Medical Tech Inc dispositivo de caracterização ótica da pele
KR20080047600A (ko) 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
RU2008114830A (ru) * 2005-09-16 2009-10-27 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Устройство ионтофореза катетерного типа
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
WO2007041118A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
JP2009509691A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面に多数の活性物質を送達するためのイオントフォレーシス装置
BRPI0616487A2 (pt) * 2005-09-30 2011-06-21 Tti Ellebeau Inc aparato e método de iontoforese para liberação sistêmica de agentes ativos
JP2009509676A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 ナノ粒子と接合された活性物質のイオントフォレーシス送達
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
WO2007038555A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
WO2007040938A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Functionalized microneedles transdermal drug delivery systems, devices, and methods
WO2007039646A1 (en) 2005-10-06 2007-04-12 Pantec Biosolutions Ag Transdermal delivery system for treating infertility
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US8226811B2 (en) * 2005-11-02 2012-07-24 May-Ruben Technologies, Inc. High impedance system for generating electric fields and method of use
CN101331392B (zh) * 2005-11-02 2012-08-08 梅-鲁宾科技公司 用于产生电场的高阻抗系统及所使用的方法
US7963917B2 (en) * 2005-12-05 2011-06-21 Echo Therapeutics, Inc. System and method for continuous non-invasive glucose monitoring
US20080033338A1 (en) * 2005-12-28 2008-02-07 Smith Gregory A Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
WO2007079193A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
EP1965858A2 (en) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System and method for remote based control of an iontophoresis device
JPWO2007091608A1 (ja) * 2006-02-10 2009-07-02 久光製薬株式会社 マイクロニードル付き経皮薬物投与装置
EP2005309B1 (en) 2006-03-30 2016-02-17 Valeritas, Inc. Multi-cartridge fluid delivery device
WO2007123707A1 (en) * 2006-03-30 2007-11-01 Tti Ellebeau, Inc. Controlled release membrane and methods of use
WO2007127339A2 (en) * 2006-04-26 2007-11-08 Tyco Healthcare Group Lp Multi-stage microporation device
US20100069849A1 (en) * 2006-06-30 2010-03-18 Kassab Ghassan S Percutaneous intravascular access to cardiac tissue
BRPI0713327A2 (pt) * 2006-07-05 2012-03-13 Tti Ellebeau, Inc. Dispositivo de liberação tendo polímeros dendríticos de auto-motagem e método de uso deste
US20100100005A1 (en) * 2006-07-11 2010-04-22 Infotonics Technology Center, Inc. Minimally invasive allergy testing system with coated allergens
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
WO2008027440A2 (en) * 2006-08-29 2008-03-06 Tti Ellebeau, Inc. An iontophoresis device and method for operation with a usb (universal serial bus) power source
CA2661879A1 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
WO2008030496A2 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Non-destructive systems, devices, and methods for evaluating iontophoresis drug delivery devices
RU2009112392A (ru) * 2006-09-05 2010-10-20 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Импедансные системы, устройства и способы для оценки ионтофоретических свойств соединений
US20100298764A1 (en) * 2006-09-06 2010-11-25 Ofer Yodfat Fluid delivery system with optical sensing of analyte concentration levels
JP2010507627A (ja) * 2006-10-25 2010-03-11 パンテック バイオソリューションズ アクチェンゲゼルシャフト 皮膚に関連した症状の広域疑似全身的治療
US7842006B2 (en) * 2006-11-17 2010-11-30 Cfd Research Corporation Thrombectomy microcatheter
TW200838576A (en) 2006-12-01 2008-10-01 Transcu Ltd Systems, devices and methods for powering and/or controlling transdermal delivery devices
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
WO2008087884A1 (ja) * 2007-01-16 2008-07-24 Tti Ellebeau, Inc. 薬物投与量の予測方法及びそのプログラム
WO2008091878A1 (en) 2007-01-22 2008-07-31 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US7713196B2 (en) * 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
US20080228056A1 (en) 2007-03-13 2008-09-18 Michael Blomquist Basal rate testing using frequent blood glucose input
US20100210932A1 (en) * 2007-03-20 2010-08-19 Bayer Healthcare Llc Method of analyzing an analyte
US20100121259A1 (en) * 2007-03-29 2010-05-13 Yacov Lutski Device and system for skin treatment
RU2482841C2 (ru) * 2007-05-18 2013-05-27 ТиТиАй Эллебо, Инк. Устройства для трансдермальной доставки, обеспечивающие улучшенное высвобождение действующего начала через биологическую поверхность
US7751907B2 (en) 2007-05-24 2010-07-06 Smiths Medical Asd, Inc. Expert system for insulin pump therapy
US8221345B2 (en) 2007-05-30 2012-07-17 Smiths Medical Asd, Inc. Insulin pump based expert system
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
US20090012446A1 (en) * 2007-07-03 2009-01-08 Xinyan Cui Devices, systems and methods for release of chemical agents
US8328720B2 (en) * 2007-08-10 2012-12-11 Infotonics Technology Center, Inc. MEMS interstitial prothrombin time test
EP2200666B1 (en) 2007-10-09 2014-12-03 Syneron Medical Ltd. Magnetic patch coupling
CA2696227A1 (en) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
US8500697B2 (en) 2007-10-19 2013-08-06 Pressure Products Medical Supplies, Inc. Transseptal guidewire
WO2009052866A1 (en) * 2007-10-25 2009-04-30 Pantec Biosolutions Ag Laser device and method for ablating biological tissue
EP2211918B1 (en) * 2007-10-29 2017-10-18 Syneron Medical Ltd. Vertical patch drying
AU2008332738B2 (en) 2007-12-05 2013-08-15 Syneron Medical Ltd. A disposable electromagnetic energy applicator and method of using it
CN103961792B (zh) 2007-12-17 2016-09-21 新世界药品有限公司 整合的真皮内递送、诊断和通讯系统
US7963947B2 (en) * 2008-01-16 2011-06-21 Pressure Products Medical Supplies, Inc. Apparatus, system, and method of shielding the sharp tip of a transseptal guidewire
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
NZ604092A (en) * 2008-03-31 2015-08-28 Nitto Denko Corp Permeant delivery system and methods for use thereof
USD610690S1 (en) 2008-04-16 2010-02-23 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
JP2011524345A (ja) * 2008-06-04 2011-09-01 コーダ セラピューティクス， インコーポレイテッド ギャップジャンクション調節化合物を用いる疼痛の治療
US8834446B2 (en) * 2008-06-12 2014-09-16 DePuy Synthes Products, LLC Pulsatile flux drug delivery
DE102008002520A1 (de) * 2008-06-19 2009-12-24 Robert Bosch Gmbh Vorrichtung zur Bestimmung und/oder Überwachung des Flüssigkeitsgehalts der Haut
US9913806B2 (en) * 2008-06-25 2018-03-13 Fe3 Medical, Inc. Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
US8404255B2 (en) * 2008-07-29 2013-03-26 Matt Gibson System and method for transdermal drug delivery
CA2964564C (en) * 2008-08-21 2019-10-22 Ninepoint Medical, Inc. Device for drug evaluation and local treatment
CA2736495A1 (en) * 2008-09-10 2010-03-18 Gregory A. Smith Apparatus and method to dispense hpc-based viscous liquids into porous substrates, e.g., continuous web-based process
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US8617487B2 (en) 2009-03-25 2013-12-31 Venture Lending & Leasing Vi, Inc. Saliva sample collection systems
US8821945B2 (en) 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20100286628A1 (en) * 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US20100312168A1 (en) * 2009-06-09 2010-12-09 Yoshimasa Yoshida Long life high capacity electrode, device, and method of manufacture
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US8641671B2 (en) 2009-07-30 2014-02-04 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
JP5406646B2 (ja) * 2009-09-16 2014-02-05 シスメックス株式会社 組織液収集方法に用いる組織液収集キット及び組織液収集シート
WO2011041463A2 (en) 2009-09-30 2011-04-07 Dexcom, Inc. Transcutaneous analyte sensor
SG170622A1 (en) * 2009-10-09 2011-05-30 Nitto Denko Corp A passive drug delivery device and a method of drug delivery
FR2955024B1 (fr) * 2010-01-14 2012-02-10 Commissariat Energie Atomique Dispositif de mise en contact transitoire d'au moins une unite de capture de cibles biologiques avec un fluide les contenant, et procede de recuperation des cibles capturees
US9993664B2 (en) * 2010-03-03 2018-06-12 Lumenis Ltd. System and methods of tissue microablation using fractional treatment patterns
WO2011115328A1 (ko) * 2010-03-16 2011-09-22 서울대학교 산학협력단 마이크로젯 약물 전달 시스템
US9327105B2 (en) 2010-03-26 2016-05-03 Itrace Biomedical Inc. Active transdermal drug delivery system and the method thereof
US9604039B2 (en) * 2010-06-18 2017-03-28 The Regents Of The University Of California Unobstructing microdevices for self-clearing implantable catheters
CN108175762A (zh) * 2010-09-23 2018-06-19 莫诺索尔克斯有限公司 用于直接在包装表面上形成药用产品的方法和系统
EP2438938A1 (en) * 2010-10-11 2012-04-11 PharmaSens AG Syringe type pump
US10707570B1 (en) * 2010-11-22 2020-07-07 Ncap Licensing, Llc Techniques for pain relief
US10244981B2 (en) * 2011-03-30 2019-04-02 SensiVida Medical Technologies, Inc. Skin test image analysis apparatuses and methods thereof
US20140303546A1 (en) * 2011-06-24 2014-10-09 University Of Miami Laser assisted delivery of functional cells, peptides and nucleotides
US9700245B2 (en) * 2011-09-23 2017-07-11 Itrace Biomedical Inc. Transdermal analyte extraction and detection system and the method thereof
US20150005595A1 (en) 2011-12-30 2015-01-01 Kibur Medical, Inc. Implantable devices and methods for evaluation of active agents
EP2797582B1 (en) 2011-12-30 2019-03-13 Kibur Medical, Inc. Implantable devices and methods for the evaluation of active agent
JP2015513905A (ja) 2012-03-27 2015-05-18 コーダ セラピューティクス， インコーポレイテッド カドヘリン調節に基づく組成物および処置
KR102183581B1 (ko) 2012-04-18 2020-11-27 싸이노슈어, 엘엘씨 피코초 레이저 장치 및 그를 사용한 표적 조직의 치료 방법
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
EP2849774A4 (en) 2012-05-18 2015-11-25 Otago Innovation Ltd COMBINATION TREATMENTS AND COMPOSITIONS FOR WOUND HEALING
US20140213866A1 (en) 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140107450A1 (en) 2012-10-12 2014-04-17 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
US10179239B2 (en) 2013-01-15 2019-01-15 Itrace Biomedical Inc. Personalized pain management treatments
US9710607B2 (en) 2013-01-15 2017-07-18 Itrace Biomedical Inc. Portable electronic therapy device and the method thereof
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9603995B2 (en) 2013-03-15 2017-03-28 Tandem Diabetes Care. Inc. Device and method for setting therapeutic parameters for an infusion device
EP2973894A2 (en) 2013-03-15 2016-01-20 Cynosure, Inc. Picosecond optical radiation systems and methods of use
US10046151B2 (en) 2013-07-03 2018-08-14 Lts Lohmann Therapie-Systeme, Ag Transdermal therapeutic system with electronic component
US10413359B2 (en) 2013-07-18 2019-09-17 International Business Machines Corporation Laser-assisted transdermal delivery of nanoparticulates and hydrogels
US9341639B2 (en) 2013-07-26 2016-05-17 Industrial Technology Research Institute Apparatus for microfluid detection
US20150289788A1 (en) 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
CN106456568B (zh) 2014-05-20 2020-03-27 Lts勒曼治疗系统股份公司 包含界面调节剂的经皮递送系统
WO2015177204A1 (en) 2014-05-20 2015-11-26 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system containing rotigotine
CA2948219C (en) 2014-05-20 2023-04-04 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
WO2016187132A1 (en) 2015-05-15 2016-11-24 ClearIt, LLC Systems and methods for tattoo removal using cold plasma
US20200324099A1 (en) * 2016-04-06 2020-10-15 Mupharma Pty Ltd Acoustic wave mediated non-invasive drug delivery
EP3338853A1 (en) 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medicament delivery device
JP6842059B2 (ja) * 2017-01-11 2021-03-17 帝人フロンティア株式会社 圧電構造体及びそれを用いたデバイス
EP3609686A4 (en) 2017-04-12 2020-09-09 The Government of the United States of America, as represented by the Secretary of the Navy TEMPERATURE-CONTROLLED ELECTRO-WIRING SUBSTRATE
ES2885062T3 (es) * 2017-06-28 2021-12-13 Fundacion Tecnalia Res & Innovation Dispositivo para la administración transdérmica controlada y vigilada de principios activos y uso del mismo
US11418000B2 (en) 2018-02-26 2022-08-16 Cynosure, Llc Q-switched cavity dumped sub-nanosecond laser
EP3801733A4 (en) * 2018-05-30 2022-07-13 Tze Guan Ong NON-INVASIVE TRANSPORTATION METHOD
DE102018215324A1 (de) * 2018-09-10 2020-03-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Herstellung von Mikrostrukturen
CN113329707B (zh) 2018-12-19 2024-10-18 科利尔皮内技术公司 用于使用所施加的电场去除纹身的系统和方法
US12138425B2 (en) 2019-05-21 2024-11-12 Tandem Diabetes Care, Inc. System and method for incorporating exercise into closed-loop diabetes therapy
AU2020306026B2 (en) * 2019-06-28 2026-01-08 Passport Technologies, Inc. Methods and systems for delivering drugs through skin of a body
US11969576B2 (en) 2019-07-03 2024-04-30 Tandem Diabetes Care, Inc. Methods of incorporating CGM data into diabetes therapy
CN110664439B (zh) * 2019-09-05 2021-07-27 华中科技大学 一种可提取皮肤组织液的微针及其制备方法
US11654236B2 (en) 2019-11-22 2023-05-23 Tandem Diabetes Care, Inc. Systems and methods for automated insulin delivery for diabetes therapy
JPWO2024080052A1 (enExample) * 2022-10-12 2024-04-18
WO2024080052A1 (ja) * 2022-10-12 2024-04-18 ヤーマン株式会社 肌処理装置及び導電シート
US12485280B1 (en) * 2024-07-15 2025-12-02 Tav-Tech Ltd Unitary enhanced jet spray dermal treatment handpiece

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5224928A (en) 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US4775361A (en) 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
US5380272A (en) * 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
AU725269B2 (en) * 1995-07-25 2000-10-12 Massachusetts Institute Of Technology Enhanced transdermal transport using ultrasound
TR199800347T1 (xx) * 1995-08-29 1998-05-21 Spectrx, Inc. �la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi.
US6234990B1 (en) * 1996-06-28 2001-05-22 Sontra Medical, Inc. Ultrasound enhancement of transdermal transport
EP0921840B1 (en) * 1996-07-03 2003-05-28 Altea Therapeutics Corporation Multiple mechanical microporation of skin or mucosa
JP4153999B2 (ja) * 1996-12-20 2008-09-24 アルザ・コーポレーション 経皮作用剤流量を強化するための組成物と方法
DE69737836T2 (de) 1996-12-31 2008-03-06 Altea Therapeutics Corp. Mikroporation von Gewebe zur Verabreichung von bioaktiven Substanzen
US6050988A (en) * 1997-12-11 2000-04-18 Alza Corporation Device for enhancing transdermal agent flux
CN1170603C (zh) * 1997-12-11 2004-10-13 阿尔扎有限公司 增强透皮物剂流量的装置
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
AU2988899A (en) 1998-03-06 1999-09-20 Altea Technologies, Inc. Integrated tissue poration, fluid harvesting and analysis device, and method therefor
PT1124607E (pt) 1998-07-14 2008-12-31 Altea Therapeutics Corp Remoção controlada de membranas biológicas por carga pirotécnica, para transporte transmembranar
EP1098594B1 (en) 1998-07-21 2007-12-12 SPECTRX, Inc. System and method for continuous analyte monitoring
DE69929979D1 (de) 1998-07-21 2006-04-27 Spectrx Inc Vorrichtung zur kontinuierlichen entnahme und analyse von flüssigkeiten
JP4531983B2 (ja) 1998-09-10 2010-08-25 アルテア セラピューティクス コーポレイション 検体の検出および／または連続的監視用の属性の補償
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6251083B1 (en) * 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body

Also Published As

Publication number Publication date
EP1189660A2 (en) 2002-03-27
CN100402105C (zh) 2008-07-16
EP2168497A3 (en) 2010-12-01
ES2260021T3 (es) 2006-11-01
JP2004505652A (ja) 2004-02-26
JP4412874B2 (ja) 2010-02-10
DE60027720T2 (de) 2007-04-26
WO2000074767A3 (en) 2001-07-05
CA2376368C (en) 2009-08-11
EP1645305A1 (en) 2006-04-12
EP2168497A2 (en) 2010-03-31
ATE324922T1 (de) 2006-06-15
WO2000074767A2 (en) 2000-12-14
CY1107518T1 (el) 2013-03-13
EP2286868A3 (en) 2012-05-16
AU5479900A (en) 2000-12-28
CN1420795A (zh) 2003-05-28
EP1189660B1 (en) 2006-05-03
EP2286868A2 (en) 2011-02-23
ZA200109966B (en) 2006-04-26
PT1189660E (pt) 2006-09-29
DE60027720D1 (de) 2006-06-08
JP2009148588A (ja) 2009-07-09
US6692456B1 (en) 2004-02-17
JP2010158554A (ja) 2010-07-22
JP5460419B2 (ja) 2014-04-02
AU780752B2 (en) 2005-04-14
CA2376368A1 (en) 2000-12-14

Similar Documents

Publication Publication Date Title
DK1189660T3 (da) Apparat til mikroperforering af biologiske membraner ved hjælp af tyndfilms-vævsgrænseflade-anordninger samt fremgangsmåde til fremstilling deraf
DE60010128D1 (de) Vorrichtung und verfahren zum spinnen von materialien
ATE313218T1 (de) Vorrichtung zur parallaxbildaufnahme und parallaxbildverarbeitung
DE502005007262D1 (de) Vorrichtung zur Durchführung einer Bestrahlungstherapie
DE60026750D1 (de) Verfahren, Vorrichtung und System zur Übertragung von optischen Überwachungssignalen
ATE346676T1 (de) Scherkraft trennverfahren und vorrichtung
SI1654387T1 (sl) Materiali in postopki za ujetje patogenov in odstranitev avrintrikarboksilne kisline iz vzorca
GB0207813D0 (en) Electrochemical detector systems
DK1088212T3 (da) Apparat og fremgangsmåde til indsamling og førstebehandling af vævsprøver til molekylærgenetisk diagnostik
DE60137166D1 (de) Verfahren, Vorrichtung, und System zur Regenerierung von optischen Signalen
DK1086408T3 (da) Styreindretning til en maskine, et system eller et apparat og en fremgangsmåde til overvågning af styreindretningen.
DE60207235D1 (de) Hohler gegenstand, vorrichtung und verfahren zur herstellung des hohlengegenständes, und mit dem hohlen gegenstand aufgebautes flüssigkeitstransportsystem
DE60111033D1 (de) Vorrichtung und verfahren zur entnahme von milchproben
BR0116529B1 (pt) aparelho, sistema e método de geração de ìon negativo.
DE60108616D1 (de) Vorrichtung und verfahren zur entnahme von milchprodukten
BRPI0309262A2 (pt) método, aparelho de transmissão de tom, e, sistema de transmissão.
DE60008599D1 (de) Endkasten für einen elektrodialysator und elektro-dialyse-verfahren
GB2441944A (en) Fieldbus system with shared redundancy system
DE60008159D1 (de) Trenn- und Analyseverfahren für Lipoproteine, Vorrichtung zur Durchführung desselben, sowie ein die Vorrichtung enthaltendes System
ATE274322T1 (de) Verfahren und vorrichtung zur eröffnung von eiern
DE69938688D1 (de) Optische Abtastvorrichtung, Vorrichtung zur Fehlerdetektion, und Detektionsverfahren dafür
EP3848183A4 (en) 3D PRINTING SYSTEM FOR MANUFACTURING AN ARTIFICIAL BLOOD VESSEL AND METHOD FOR MANUFACTURING AN ARTIFICIAL BLOOD VESSEL THEREFORE
ATE443256T1 (de) Verfahren und vorrichtung zur feststellung des blutsauerstofftransportes
DE58905677D1 (de) Vorrichtung zur Durchführung von Membrantrennprozessen.
ITRM20010197A1 (it) Dispositivo, apparato e metodo per elettrostimolazione.