DK1154987T3 - Phenylalaninolderivater - Google Patents
PhenylalaninolderivaterInfo
- Publication number
- DK1154987T3 DK1154987T3 DK00903692T DK00903692T DK1154987T3 DK 1154987 T3 DK1154987 T3 DK 1154987T3 DK 00903692 T DK00903692 T DK 00903692T DK 00903692 T DK00903692 T DK 00903692T DK 1154987 T3 DK1154987 T3 DK 1154987T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- lower alkyl
- alkanoyl
- aryl
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/80—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12049899P | 1999-02-18 | 1999-02-18 | |
| PCT/EP2000/001168 WO2000048988A1 (en) | 1999-02-18 | 2000-02-12 | Phenylalaninol derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1154987T3 true DK1154987T3 (da) | 2004-08-09 |
Family
ID=22390691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00903692T DK1154987T3 (da) | 1999-02-18 | 2000-02-12 | Phenylalaninolderivater |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6420600B1 (de) |
| EP (1) | EP1154987B1 (de) |
| JP (1) | JP2002537283A (de) |
| KR (1) | KR100636458B1 (de) |
| CN (1) | CN1213020C (de) |
| AT (1) | ATE264835T1 (de) |
| AU (1) | AU771938B2 (de) |
| BR (1) | BR0008368A (de) |
| CA (1) | CA2362833C (de) |
| CZ (1) | CZ20012984A3 (de) |
| DE (1) | DE60010049T2 (de) |
| DK (1) | DK1154987T3 (de) |
| ES (1) | ES2218116T3 (de) |
| HK (1) | HK1043589A1 (de) |
| HR (1) | HRP20010594B1 (de) |
| HU (1) | HUP0200343A3 (de) |
| ID (1) | ID30057A (de) |
| IL (2) | IL144641A0 (de) |
| MA (1) | MA26772A1 (de) |
| MX (1) | MXPA01008178A (de) |
| NO (1) | NO20013946L (de) |
| PL (1) | PL349463A1 (de) |
| PT (1) | PT1154987E (de) |
| RU (1) | RU2238265C2 (de) |
| SI (1) | SI1154987T1 (de) |
| TR (1) | TR200102395T2 (de) |
| WO (1) | WO2000048988A1 (de) |
| YU (1) | YU58601A (de) |
| ZA (1) | ZA200106075B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6939855B2 (en) | 1997-07-31 | 2005-09-06 | Elan Pharmaceuticals, Inc. | Anti-inflammatory compositions and method |
| JP2003506491A (ja) * | 1999-08-13 | 2003-02-18 | バイオジェン インコーポレイテッド | 細胞接着インヒビター |
| US6380387B1 (en) | 1999-12-06 | 2002-04-30 | Hoffmann-La Roche Inc. | 4-Pyrimidinyl-n-acyl-l phenylalanines |
| US6388084B1 (en) | 1999-12-06 | 2002-05-14 | Hoffmann-La Roche Inc. | 4-pyridinyl-n-acyl-l-phenylalanines |
| AU2004240940A1 (en) | 2003-05-20 | 2004-12-02 | Genentech, Inc. | Thiocarbamate inhibitors of alpha-4 integrins |
| WO2006081986A1 (en) * | 2005-02-07 | 2006-08-10 | F.Hoffmann-La Roche Ag | Bambuterol and integrin inhibitor combination |
| WO2006094640A2 (en) * | 2005-03-04 | 2006-09-14 | F.Hoffmann-La Roche Ag | Roflumilast and integrin inhibitor combination and method of treatment |
| IL172896A0 (en) * | 2005-12-29 | 2006-06-11 | Yeda Res & Dev | Cxcr4 inhibition |
| US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE584914A (de) | 1958-11-24 | |||
| US3527793A (en) | 1967-08-18 | 1970-09-08 | Bristol Myers Co | Phenylglycine derivatives |
| IT1190378B (it) | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| US5039805A (en) | 1988-12-08 | 1991-08-13 | Hoffmann-La Roche Inc. | Novel benzoic and phenylacetic acid derivatives |
| US5463116A (en) | 1991-07-30 | 1995-10-31 | Ajinomoto Co., Inc. | Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them |
| WO1995035296A1 (en) | 1994-06-20 | 1995-12-28 | Takeda Chemical Industries, Ltd. | Condensed imidazole compounds, their production and use |
| US6306840B1 (en) | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| US5804595A (en) | 1995-12-05 | 1998-09-08 | Regents Of The University Of Minnesota | Kappa opioid receptor agonists |
| ES2162676T3 (es) | 1996-03-29 | 2002-01-01 | Searle & Co | Derivados de fenileno sustituidos en meta y su uso como antagonistas o inhibidores de integrina alfav,beta3. |
| PT891325E (pt) * | 1996-03-29 | 2002-07-31 | Searle & Co | Derivados do acido fenilpropanoico para-substituido como antagonistas de integrina |
| ID19155A (id) * | 1996-12-13 | 1998-06-18 | Tanabe Seiyaku Co | Turunan-turunan piridin, pembuatannya dan intermediet untuk pembuatannya |
| CA2291778A1 (en) * | 1997-05-29 | 1998-12-03 | Merck & Co., Inc. | Heterocyclic amide compounds as cell adhesion inhibitors |
| HU229362B1 (en) * | 1997-08-22 | 2013-11-28 | Hoffmann La Roche | N-alkanoylphenylalanine derivatives |
| ES2214728T3 (es) * | 1997-08-22 | 2004-09-16 | F. Hoffmann-La Roche Ag | Derivados de n-aroilfenilalanina. |
| EP1056714B1 (de) | 1998-02-26 | 2004-08-11 | Celltech Therapeutics Limited | Phenylalaninderivate als inhibitoren von alpha4 integrinen |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| GB9811159D0 (en) | 1998-05-22 | 1998-07-22 | Celltech Therapeutics Ltd | Chemical compounds |
-
2000
- 2000-02-12 PL PL00349463A patent/PL349463A1/xx not_active Application Discontinuation
- 2000-02-12 CN CNB008038694A patent/CN1213020C/zh not_active Expired - Fee Related
- 2000-02-12 KR KR1020017010537A patent/KR100636458B1/ko not_active IP Right Cessation
- 2000-02-12 SI SI200030405T patent/SI1154987T1/xx unknown
- 2000-02-12 CA CA002362833A patent/CA2362833C/en not_active Expired - Fee Related
- 2000-02-12 MX MXPA01008178A patent/MXPA01008178A/es active IP Right Grant
- 2000-02-12 AT AT00903692T patent/ATE264835T1/de not_active IP Right Cessation
- 2000-02-12 BR BR0008368-2A patent/BR0008368A/pt not_active Application Discontinuation
- 2000-02-12 AU AU25486/00A patent/AU771938B2/en not_active Ceased
- 2000-02-12 ID IDW00200101769A patent/ID30057A/id unknown
- 2000-02-12 PT PT00903692T patent/PT1154987E/pt unknown
- 2000-02-12 EP EP00903692A patent/EP1154987B1/de not_active Expired - Lifetime
- 2000-02-12 ES ES00903692T patent/ES2218116T3/es not_active Expired - Lifetime
- 2000-02-12 DK DK00903692T patent/DK1154987T3/da active
- 2000-02-12 WO PCT/EP2000/001168 patent/WO2000048988A1/en active IP Right Grant
- 2000-02-12 RU RU2001124601A patent/RU2238265C2/ru not_active IP Right Cessation
- 2000-02-12 CZ CZ20012984A patent/CZ20012984A3/cs unknown
- 2000-02-12 TR TR2001/02395T patent/TR200102395T2/xx unknown
- 2000-02-12 DE DE60010049T patent/DE60010049T2/de not_active Expired - Lifetime
- 2000-02-12 YU YU58601A patent/YU58601A/sh unknown
- 2000-02-12 HU HU0200343A patent/HUP0200343A3/hu unknown
- 2000-02-12 JP JP2000599729A patent/JP2002537283A/ja active Pending
- 2000-02-12 IL IL14464100A patent/IL144641A0/xx active IP Right Grant
- 2000-02-17 US US09/506,062 patent/US6420600B1/en not_active Expired - Fee Related
-
2001
- 2001-07-24 ZA ZA200106075A patent/ZA200106075B/en unknown
- 2001-07-30 IL IL144641A patent/IL144641A/en not_active IP Right Cessation
- 2001-08-10 HR HR20010594A patent/HRP20010594B1/xx not_active IP Right Cessation
- 2001-08-14 NO NO20013946A patent/NO20013946L/no not_active Application Discontinuation
- 2001-08-17 MA MA26298A patent/MA26772A1/fr unknown
-
2002
- 2002-07-22 HK HK02105393A patent/HK1043589A1/xx not_active IP Right Cessation
Also Published As
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