DK1146892T3 - BAFF, inhibitorer deraf og deres anvendelse i modulationen af B-celle responset - Google Patents

BAFF, inhibitorer deraf og deres anvendelse i modulationen af B-celle responset

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Publication number
DK1146892T3
DK1146892T3 DK00909970T DK00909970T DK1146892T3 DK 1146892 T3 DK1146892 T3 DK 1146892T3 DK 00909970 T DK00909970 T DK 00909970T DK 00909970 T DK00909970 T DK 00909970T DK 1146892 T3 DK1146892 T3 DK 1146892T3
Authority
DK
Denmark
Prior art keywords
cell growth
baff
immunoglobulin production
ligand
cell
Prior art date
Application number
DK00909970T
Other languages
Danish (da)
English (en)
Inventor
Jeffrey Browning
Christine Ambrose
Jurg Tschopp
Pascal Schneider
Fabienne Mackay
Original Assignee
Apoxis Sa
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26815006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1146892(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Apoxis Sa, Biogen Inc filed Critical Apoxis Sa
Application granted granted Critical
Publication of DK1146892T3 publication Critical patent/DK1146892T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2227/10—Mammal
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DK00909970T 1999-01-25 2000-01-25 BAFF, inhibitorer deraf og deres anvendelse i modulationen af B-celle responset DK1146892T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11716999P 1999-01-25 1999-01-25
US14322899P 1999-07-09 1999-07-09
PCT/US2000/001788 WO2000043032A2 (en) 1999-01-25 2000-01-25 Baff, inhibitors thereof and their use in the modulation of b-cell response

Publications (1)

Publication Number Publication Date
DK1146892T3 true DK1146892T3 (da) 2003-11-24

Family

ID=26815006

Family Applications (2)

Application Number Title Priority Date Filing Date
DK00909970T DK1146892T3 (da) 1999-01-25 2000-01-25 BAFF, inhibitorer deraf og deres anvendelse i modulationen af B-celle responset
DK03018879.1T DK1415659T3 (da) 1999-01-25 2000-01-25 BAFF, inhibitorer og anvendelse deraf i modulering af B-cellerespons

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03018879.1T DK1415659T3 (da) 1999-01-25 2000-01-25 BAFF, inhibitorer og anvendelse deraf i modulering af B-cellerespons

Country Status (29)

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US (1) US6869605B2 (pt)
EP (5) EP2298332B1 (pt)
JP (5) JP5066314B2 (pt)
KR (1) KR100834809B1 (pt)
CN (1) CN100340292C (pt)
AT (2) ATE247482T1 (pt)
AU (1) AU762839B2 (pt)
BR (1) BR0007719A (pt)
CA (1) CA2360062A1 (pt)
CY (2) CY1107453T1 (pt)
CZ (1) CZ299819B6 (pt)
DE (1) DE60004635T2 (pt)
DK (2) DK1146892T3 (pt)
EA (1) EA006108B1 (pt)
EE (1) EE05699B1 (pt)
ES (1) ES2204528T3 (pt)
HK (2) HK1040628B (pt)
HU (1) HUP0105283A3 (pt)
IL (3) IL144202A0 (pt)
IS (1) IS5993A (pt)
MX (1) MXPA01007464A (pt)
NO (2) NO20013641L (pt)
NZ (1) NZ513284A (pt)
PL (1) PL198934B1 (pt)
PT (2) PT1415659E (pt)
SI (1) SI1146892T1 (pt)
SK (1) SK286665B6 (pt)
TR (2) TR200102147T2 (pt)
WO (1) WO2000043032A2 (pt)

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UA74798C2 (uk) 1999-10-06 2006-02-15 Байоджен Айдек Ма Інк. Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами
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