DK1137808T3 - Fremgangsmåde til fremstilling af rekombinante celler - Google Patents

Fremgangsmåde til fremstilling af rekombinante celler

Info

Publication number
DK1137808T3
DK1137808T3 DK99961864T DK99961864T DK1137808T3 DK 1137808 T3 DK1137808 T3 DK 1137808T3 DK 99961864 T DK99961864 T DK 99961864T DK 99961864 T DK99961864 T DK 99961864T DK 1137808 T3 DK1137808 T3 DK 1137808T3
Authority
DK
Denmark
Prior art keywords
recombinant
cell lines
recombinant cells
producing recombinant
amino acid
Prior art date
Application number
DK99961864T
Other languages
Danish (da)
English (en)
Inventor
Peter R Rhode
Jorge L Acevedo
Original Assignee
Sunol Molecular Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunol Molecular Corp filed Critical Sunol Molecular Corp
Application granted granted Critical
Publication of DK1137808T3 publication Critical patent/DK1137808T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK99961864T 1998-12-03 1999-11-30 Fremgangsmåde til fremstilling af rekombinante celler DK1137808T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/204,979 US6156514A (en) 1998-12-03 1998-12-03 Methods for making recombinant cells
EP99961864A EP1137808B1 (de) 1998-12-03 1999-11-30 Methode zur herstellung von rekombinanten zellen

Publications (1)

Publication Number Publication Date
DK1137808T3 true DK1137808T3 (da) 2005-01-31

Family

ID=22760275

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99961864T DK1137808T3 (da) 1998-12-03 1999-11-30 Fremgangsmåde til fremstilling af rekombinante celler

Country Status (12)

Country Link
US (2) US6156514A (de)
EP (1) EP1137808B1 (de)
JP (1) JP2002531103A (de)
CN (1) CN1202261C (de)
AT (1) ATE278024T1 (de)
AU (1) AU770119B2 (de)
CA (1) CA2353575A1 (de)
DE (1) DE69920747T2 (de)
DK (1) DK1137808T3 (de)
ES (1) ES2230908T3 (de)
TW (1) TWI221483B (de)
WO (1) WO2000032821A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030224415A1 (en) * 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
US6852510B2 (en) * 2000-07-03 2005-02-08 Gala Design Inc Host cells containing multiple integrating vectors
WO2003064659A1 (en) * 2002-01-11 2003-08-07 Genetica, Inc. Methods and compositions for optimizing recombinant expression
CA2486464A1 (en) 2002-05-21 2003-11-27 Resistentia Pharmaceuticals Ab Chimeric ige polypeptides and host cells
BRPI0406470A (pt) * 2003-01-09 2005-12-06 Genentech Inc Método para a purificação de polipeptìdeo heterólogo e caldo ou homogeneizado de fermentação
US20050221429A1 (en) * 2004-01-16 2005-10-06 Cardinal Health Pts, Llc Host cells containing multiple integrating vectors comprising an amplifiable marker
EP1982176A1 (de) * 2006-01-30 2008-10-22 Dako Denmark A/S Quantifizierung antigenspezifischer t-zellen in vollblut mit hoher geschwindigkeit mittels durchflusszytometrie
EP2155782A2 (de) 2007-03-26 2010-02-24 Dako Denmark A/S Mhc-peptid-komplexe und anwendungen davon bei infektionskrankheiten
EP2167536A1 (de) * 2007-07-03 2010-03-31 Dako Denmark A/S Mhc-multimere, verfahren zu ihrer herstellung, markierung und verwendung
WO2009039854A2 (en) 2007-09-27 2009-04-02 Dako Denmark A/S Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
US10722562B2 (en) * 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US10369204B2 (en) 2008-10-02 2019-08-06 Dako Denmark A/S Molecular vaccines for infectious disease
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
US20100183558A1 (en) 2008-10-17 2010-07-22 Zhennan Lai Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules
WO2017007994A1 (en) 2015-07-08 2017-01-12 American Gene Technologies International Inc. Hiv pre-immunization and immunotherapy
WO2017123918A1 (en) 2016-01-15 2017-07-20 American Gene Technologies International Inc. Methods and compositons for the activation of gamma-delta t-cells
US10137144B2 (en) 2016-01-15 2018-11-27 American Gene Technologies International Inc. Methods and compositions for the activation of gamma-delta T-cells
US10888613B2 (en) 2016-02-08 2021-01-12 American Gene Technologies International Inc. Method of producing cells resistant to HIV infection
EP4036231A1 (de) 2016-03-09 2022-08-03 American Gene Technologies International Inc. Kombinationsvektoren und verfahren zur behandlung von krebs
EP3468617A4 (de) * 2016-06-08 2020-01-22 American Gene Technologies International Inc. System zur nichtintegralen viralen ausgabe und verfahren im zusammenhang damit
AU2017292582C1 (en) 2016-07-08 2021-11-11 American Gene Technologies International Inc. HIV pre-immunization and immunotherapy
WO2018017882A1 (en) 2016-07-21 2018-01-25 American Gene Technologies International Inc. Viral vectors for treating parkinson's disease
EP3607072A4 (de) 2017-04-03 2021-01-06 American Gene Technologies International Inc. Zusammensetzungen und verfahren zur behandlung von phenylketonurie

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3167442D1 (en) * 1980-07-07 1985-01-10 Nat Res Dev Improvements in or relating to cell lines
US4766067A (en) * 1985-05-31 1988-08-23 President And Fellows Of Harvard College Gene amplification
IL80511A0 (en) * 1985-11-05 1987-02-27 Genetics Inst Multiply amplifiable vectors for high level expression of exogenous dna
RU2091487C1 (ru) * 1987-02-27 1997-09-27 Гист-Брокейдс Н.В. Способ получения штамма bacillus, содержащего две копии последовательности днк, кодирующей фермент с гидролазной активностью
US4956288A (en) * 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
WO1989010959A1 (en) * 1988-05-06 1989-11-16 Codon Supertransformants for high expression rates in eukaryotic cells
AU4741090A (en) * 1988-12-08 1990-06-26 Damon Biotech Inc. Expression induction method employing mutant dhfr gene
ATE263837T1 (de) * 1991-05-31 2004-04-15 Genentech Inc Expressionsteigerung durch gentargeting in endogene retrovirus-ähnliche sequenzen
US5733761A (en) * 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5420019A (en) * 1993-02-02 1995-05-30 Xoma Corporation Stable bactericidal/permeability-increasing protein muteins
SG48813A1 (en) * 1993-08-12 1998-05-18 Cytotherapeutics Inc Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5585237A (en) * 1993-10-25 1996-12-17 Creative Biomolecules, Inc. Methods and compositions for high protein production from recombinant DNA
US5733782A (en) * 1993-10-25 1998-03-31 Creative Biomolecules, Inc. Methods and compositions for high protein production from non-native DNA
WO1995017513A1 (en) * 1993-12-23 1995-06-29 Novo Nordisk A/S Retransformation of filamentous fungi
US5776746A (en) * 1996-05-01 1998-07-07 Genitope Corporation Gene amplification methods

Also Published As

Publication number Publication date
TWI221483B (en) 2004-10-01
EP1137808A1 (de) 2001-10-04
EP1137808B1 (de) 2004-09-29
AU770119B2 (en) 2004-02-12
DE69920747D1 (de) 2004-11-04
ES2230908T3 (es) 2005-05-01
DE69920747T2 (de) 2005-10-06
CA2353575A1 (en) 2000-06-08
CN1202261C (zh) 2005-05-18
US6306605B1 (en) 2001-10-23
US6156514A (en) 2000-12-05
EP1137808A4 (de) 2002-10-02
ATE278024T1 (de) 2004-10-15
JP2002531103A (ja) 2002-09-24
WO2000032821A1 (en) 2000-06-08
CN1328605A (zh) 2001-12-26
AU1835600A (en) 2000-06-19

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