DK1135401T3 - Glycerylnucleotider, fremgangsmåder til deres fremstilling og deres anvendelse - Google Patents

Glycerylnucleotider, fremgangsmåder til deres fremstilling og deres anvendelse

Info

Publication number
DK1135401T3
DK1135401T3 DK99958161T DK99958161T DK1135401T3 DK 1135401 T3 DK1135401 T3 DK 1135401T3 DK 99958161 T DK99958161 T DK 99958161T DK 99958161 T DK99958161 T DK 99958161T DK 1135401 T3 DK1135401 T3 DK 1135401T3
Authority
DK
Denmark
Prior art keywords
radicals
nucleoside
compounds
processes
group
Prior art date
Application number
DK99958161T
Other languages
Danish (da)
English (en)
Inventor
Herbert Schott
Peter Stephan Ludwig
Original Assignee
Herbert Schott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Herbert Schott filed Critical Herbert Schott
Application granted granted Critical
Publication of DK1135401T3 publication Critical patent/DK1135401T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK99958161T 1998-12-04 1999-12-03 Glycerylnucleotider, fremgangsmåder til deres fremstilling og deres anvendelse DK1135401T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19855963A DE19855963A1 (de) 1998-12-04 1998-12-04 Amphiphile Glycerylnucleotide, Verfahren zu ihrer Herstellung und ihre Verwendung
PCT/EP1999/009461 WO2000034298A1 (fr) 1998-12-04 1999-12-03 Glyceryle-nucleotides, leur procede de production et leur utilisation

Publications (1)

Publication Number Publication Date
DK1135401T3 true DK1135401T3 (da) 2003-10-06

Family

ID=7889957

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99958161T DK1135401T3 (da) 1998-12-04 1999-12-03 Glycerylnucleotider, fremgangsmåder til deres fremstilling og deres anvendelse

Country Status (10)

Country Link
US (1) US6787525B1 (fr)
EP (1) EP1135401B1 (fr)
JP (1) JP4879398B2 (fr)
AT (1) ATE243220T1 (fr)
AU (1) AU1558800A (fr)
CA (1) CA2352229C (fr)
DE (2) DE19855963A1 (fr)
DK (1) DK1135401T3 (fr)
ES (1) ES2201805T3 (fr)
WO (1) WO2000034298A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10228059B4 (de) * 2002-06-19 2005-12-29 Eberhard-Karls-Universität Tübingen Verwendung von amphiphilen Nucleosid-Phosphonoameisensäure-Derivaten zur Behandlung von viralen Infektionskrankheiten
US7593913B2 (en) * 2006-01-11 2009-09-22 Siemens Medical Solutions Usa, Inc. Systems and method for integrative medical decision support
WO2012040124A1 (fr) 2010-09-22 2012-03-29 Alios Biopharma, Inc. Azido nucléosides et analogues nucléotidiques
CN104114568B (zh) 2011-12-22 2017-09-01 艾丽奥斯生物制药有限公司 取代的核苷、核苷酸及其类似物
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
PL2861611T3 (pl) 2012-05-25 2017-08-31 Janssen Sciences Ireland Uc Nukleozydy uracylowe spirooksetanu
EA201590943A1 (ru) 2012-12-21 2016-01-29 Алиос Биофарма, Инк. Замещенные нуклеозиды, нуклеотиды и их аналоги
CN113712989A (zh) 2013-10-11 2021-11-30 艾丽奥斯生物制药有限公司 取代的核苷、核苷酸及其类似物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03236396A (ja) * 1990-02-10 1991-10-22 Tosoh Corp 修飾オリゴデオキシヌクレオチド及びそれを含むｄｎａ
JPH0421694A (ja) * 1990-05-16 1992-01-24 Asahi Chem Ind Co Ltd 新規なヌクレオシド―リン脂質複合体
DE69119074T2 (de) * 1990-06-15 1996-12-12 University Of North Carolina At Chapel Hill, Chapel Hill, N.C. Kovalente-ther lipidnukleosid-konjugate
CA2129986C (fr) * 1992-02-13 2003-12-09 Albert Reto Schwendener Analogues de nucleosidephosphates amphiphiles
DE4418690A1 (de) * 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
JP4259611B2 (ja) * 1994-08-29 2009-04-30 ウェイク フォレスト ユニバーシティ ウィルス感染を治療するための脂質アナログ
AU3120797A (en) * 1996-05-08 1998-07-31 Weider Nutrition Group, Inc. Structured glycerols and structured phosphatides
US6686462B2 (en) 1997-02-28 2004-02-03 The Regents Of The University Of California Antiviral compounds and methods of administration

Also Published As

Publication number Publication date
JP4879398B2 (ja) 2012-02-22
ATE243220T1 (de) 2003-07-15
ES2201805T3 (es) 2004-03-16
DE59906041D1 (de) 2003-07-24
JP2002531573A (ja) 2002-09-24
WO2000034298A1 (fr) 2000-06-15
CA2352229A1 (fr) 2000-06-15
CA2352229C (fr) 2009-06-09
EP1135401B1 (fr) 2003-06-18
AU1558800A (en) 2000-06-26
DE19855963A1 (de) 2000-06-08
US6787525B1 (en) 2004-09-07
EP1135401A1 (fr) 2001-09-26

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