DK1126874T3 - Multikomponent Meningococcus Vaccine - Google Patents

Multikomponent Meningococcus Vaccine

Info

Publication number
DK1126874T3
DK1126874T3 DK99954130T DK99954130T DK1126874T3 DK 1126874 T3 DK1126874 T3 DK 1126874T3 DK 99954130 T DK99954130 T DK 99954130T DK 99954130 T DK99954130 T DK 99954130T DK 1126874 T3 DK1126874 T3 DK 1126874T3
Authority
DK
Denmark
Prior art keywords
multicomponent
meningococcus vaccine
meningococcus
vaccine
outer membrane
Prior art date
Application number
DK99954130T
Other languages
English (en)
Other versions
DK1126874T4 (da
DK1126874T5 (da
Inventor
Andrew Robinson
Andrew R Gorringe
Michael John Hudson
Karen M Reddin
Original Assignee
Health Prot Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10841713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1126874(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Health Prot Agency filed Critical Health Prot Agency
Publication of DK1126874T3 publication Critical patent/DK1126874T3/da
Publication of DK1126874T4 publication Critical patent/DK1126874T4/da
Application granted granted Critical
Publication of DK1126874T5 publication Critical patent/DK1126874T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DK99954130T 1998-11-02 1999-11-02 Multikomponent Meningococcus Vaccine DK1126874T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9823978.3A GB9823978D0 (en) 1998-11-02 1998-11-02 Multicomponent meningococcal vaccine
PCT/GB1999/003626 WO2000025811A2 (en) 1998-11-02 1999-11-02 Multicomponent meningococcal vaccine

Publications (3)

Publication Number Publication Date
DK1126874T3 true DK1126874T3 (da) 2003-09-29
DK1126874T4 DK1126874T4 (da) 2008-10-13
DK1126874T5 DK1126874T5 (da) 2008-12-01

Family

ID=10841713

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99954130T DK1126874T5 (da) 1998-11-02 1999-11-02 Multikomponent Meningococcus Vaccine

Country Status (13)

Country Link
US (2) US6821521B1 (da)
EP (3) EP1126874B2 (da)
JP (2) JP2002528515A (da)
AT (1) ATE242640T1 (da)
AU (1) AU760858B2 (da)
BR (1) BR9914946A (da)
CA (1) CA2349331A1 (da)
DE (1) DE69908805T3 (da)
DK (1) DK1126874T5 (da)
ES (1) ES2197688T5 (da)
GB (1) GB9823978D0 (da)
PT (1) PT1126874E (da)
WO (1) WO2000025811A2 (da)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030215469A1 (en) * 1998-11-02 2003-11-20 Microbiological Research Authority Multicomponent meningococcal vaccine
GB9823978D0 (en) * 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
US10967045B2 (en) 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
US7081244B2 (en) 1999-02-22 2006-07-25 Health Protection Agency Neisserial vaccine compositions and methods
JP4982009B2 (ja) * 1999-02-22 2012-07-25 ヘルス プロテクション エージェンシー ナイセリアワクチン組成物および方法
DK2270173T3 (da) 1999-05-19 2016-03-07 Glaxosmithkline Biolog Sa Neisseriale kombinationssammensætninger
DK1248647T3 (da) 2000-01-17 2010-09-27 Novartis Vaccines & Diagnostic Ydre membranvesikel (OMV) vaccine omfattende N. meningitidis serogruppe B ydre membranproteiner
MXPA03000822A (es) 2000-07-27 2004-11-01 Childrens Hosp & Res Ct Oak Vacunas para proteccion de espectro amplio contra enfermedades causadas por neisseria meningitidis.
GB0130123D0 (en) * 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
PT2255826E (pt) * 2002-08-02 2016-06-08 Glaxosmithkline Biologicals Sa Composições de vacina de neisseria compreendendo uma combinação de antigénios
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
ES2608048T3 (es) 2002-10-11 2017-04-05 Glaxosmithkline Biologicals Sa Vacunas polipeptídicas para protección amplia contra linajes meningocócicos hipervirulentos
US20070059329A1 (en) 2002-11-15 2007-03-15 Nathalie Norais Unexpected surface proteins in meningococcus
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
CA2514328C (en) 2003-01-30 2020-01-14 Chiron Srl Injectable vaccines against multiple meningococcal serogroups
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
CU23377A1 (es) * 2003-11-04 2009-05-28 Ct De Ingenieria Genetica Y Biotecnologia Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
CN101107007B (zh) 2005-01-27 2011-08-17 奥克兰儿童医院及研究中心 对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US7917240B2 (en) 2006-09-29 2011-03-29 Fisher-Rosemount Systems, Inc. Univariate method for monitoring and analysis of multivariate data
US7378713B2 (en) * 2006-10-25 2008-05-27 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor devices with dual-metal gate structures and fabrication methods thereof
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
DK2200642T3 (da) 2007-10-19 2012-07-16 Novartis Ag Meningococvaccinepræparater
CA2716212A1 (en) 2008-02-21 2009-08-27 Novartis Ag Meningococcal fhbp polypeptides
US8466167B2 (en) 2008-03-03 2013-06-18 Irm Llc Compounds and compositions as TLR activity modulators
JP5723768B2 (ja) 2008-05-30 2015-05-27 ザ ユナイテッド ステイツ オブ アメリカ， アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー， オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ 髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
CA2747340A1 (en) 2008-12-17 2010-06-24 Novartis Ag Meningococcal vaccines including hemoglobin receptor
WO2010130899A1 (fr) * 2009-05-14 2010-11-18 Sanofi Pasteur Vaccin meningocoque a base de lipooligosaccharide (los) et de proteine de neisseria meningitidis
CA2761916A1 (fr) 2009-05-14 2010-11-18 Sanofi Pasteur Procede pour adjuver le lipopolysaccharide (lps) des bacteries a gram-negatif
CA2765112A1 (en) 2009-06-10 2010-12-16 Novartis Ag Benzonaphthyridine-containing vaccines
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
CA2772104A1 (en) 2009-08-27 2011-03-03 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
GB0916557D0 (en) 2009-09-21 2009-10-28 Health Prot Agency Commensal neisserial stress protein complexes
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
CA2779816A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
US9408907B2 (en) 2009-12-15 2016-08-09 Glaxosmithkline Biologicals Sa Homogenous suspension of immunopotentiating compounds and uses thereof
JP2013521327A (ja) 2010-03-10 2013-06-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原性組成物
CA2793510A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
EP2549990A1 (en) 2010-03-23 2013-01-30 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
WO2012038801A1 (en) 2010-09-21 2012-03-29 National Institute Of Immunology A spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles
WO2012153302A1 (en) 2011-05-12 2012-11-15 Novartis Ag Antipyretics to enhance tolerability of vesicle-based vaccines
GB201110980D0 (en) 2011-06-28 2011-08-10 Health Prot Agency Neisserial compositions and expression constructs
RU2014135522A (ru) 2012-02-02 2016-03-27 Новартис Аг Промоторы для увеличенной экспрессии белка у менингококка
WO2014016152A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
US9526776B2 (en) 2012-09-06 2016-12-27 Glaxosmithkline Biologicals Sa Combination vaccines with serogroup B meningococcus and D/T/P
MX2016011176A (es) 2014-02-28 2017-02-23 Glaxosmithkline Biologicals Sa Polipeptidos fhbp meningococicos modificados.
EP3302511A1 (en) * 2015-06-02 2018-04-11 De Staat der Nederlanden, vert. door de Minister van VWS Surface display of antigens on gram-negative outer membrane vesicles

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
RU2023448C1 (ru) 1987-07-30 1994-11-30 Сентро Насьональ Де Биопрепарадос Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
US5292869A (en) * 1989-04-27 1994-03-08 The Board Of Governors Of The University Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
FR2682041B1 (fr) 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
NL9201716A (nl) * 1992-10-02 1994-05-02 Nederlanden Staat Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
US6287574B1 (en) * 1995-03-17 2001-09-11 Biochem Pharma Inc. Proteinase K resistant surface protein of neisseria meningitidis
US6180111B1 (en) 1995-05-18 2001-01-30 University Of Maryland Vaccine delivery system
US6558677B2 (en) * 1996-10-15 2003-05-06 Wendell D. Zollinger Vaccine against gram negative bacteria
GB9711964D0 (en) 1997-06-09 1997-08-06 Medical Res Council Live attenuated vaccines
AU748973B2 (en) * 1997-07-17 2002-06-13 Baxter Healthcare Sa Immunogenic conjugates comprising a group B meningococcal porin and an H. influenzae polysaccharide
US10967045B2 (en) * 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
GB9823978D0 (en) * 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
DK2270173T3 (da) * 1999-05-19 2016-03-07 Glaxosmithkline Biolog Sa Neisseriale kombinationssammensætninger
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
DK1248647T3 (da) * 2000-01-17 2010-09-27 Novartis Vaccines & Diagnostic Ydre membranvesikel (OMV) vaccine omfattende N. meningitidis serogruppe B ydre membranproteiner
MXPA03000822A (es) * 2000-07-27 2004-11-01 Childrens Hosp & Res Ct Oak Vacunas para proteccion de espectro amplio contra enfermedades causadas por neisseria meningitidis.
GB0130123D0 (en) * 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
PT2255826E (pt) * 2002-08-02 2016-06-08 Glaxosmithkline Biologicals Sa Composições de vacina de neisseria compreendendo uma combinação de antigénios
US20070059329A1 (en) * 2002-11-15 2007-03-15 Nathalie Norais Unexpected surface proteins in meningococcus
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
CA2695467A1 (en) * 2007-08-02 2009-03-26 Children's Hospital & Research Center At Oakland Fhbp- and lpxl1-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis

Also Published As

Publication number Publication date
ES2197688T5 (es) 2008-12-16
ES2197688T3 (es) 2004-01-01
BR9914946A (pt) 2001-07-10
JP2012025774A (ja) 2012-02-09
DE69908805D1 (de) 2003-07-17
EP1126874A2 (en) 2001-08-29
ATE242640T1 (de) 2003-06-15
EP1126874B1 (en) 2003-06-11
GB9823978D0 (en) 1998-12-30
EP2248535A1 (en) 2010-11-10
AU1056900A (en) 2000-05-22
DE69908805T2 (de) 2004-05-19
DE69908805T3 (de) 2008-12-24
EP1297844A2 (en) 2003-04-02
US20090148469A1 (en) 2009-06-11
WO2000025811A3 (en) 2000-10-05
PT1126874E (pt) 2003-10-31
US6821521B1 (en) 2004-11-23
EP1126874B2 (en) 2008-06-25
CA2349331A1 (en) 2000-05-11
WO2000025811A2 (en) 2000-05-11
DK1126874T4 (da) 2008-10-13
EP1297844A3 (en) 2004-01-14
DK1126874T5 (da) 2008-12-01
JP2002528515A (ja) 2002-09-03
AU760858B2 (en) 2003-05-22

Similar Documents

Publication Publication Date Title
DK1126874T3 (da) Multikomponent Meningococcus Vaccine
IT1283222B1 (it) Membrana composita integrale
NO951655D0 (no) Brannmotstandsdyktig treplate med orienterte fibre som konstruksjonselement
DE69201113T2 (de) Aromastoffe enthaltende, orale Peroxid-Bicarbonat Zusammensetzung.
DK0741779T3 (da) Fortykket, stabil, sur rengøringssammensætning i form af en mikroemulsion
NO20000202L (no) Immunogene konjugater som omfatter en gruppe B- meningokokkporin og et H. influenzae-polysakkarid
DE69115514D1 (de) Liposomenhaltige intranasale Impfstofformulierung
PL352011A1 (en) Compositions for dyeing kerating fibres, containing para-phenylenediamine derivatives with pyrrolidinyl group
BR9504358A (pt) Membrana anisotrópica
NO972219D0 (no) Immunogenpreparater
FR2749751B1 (fr) Ensemble moteur-piece a main a contre-angle avec un moteur pas-a-pas
FI880819A0 (fi) Smaeltugn och foerfarande foer matning av det material, som behandlas in i den.
ATE109465T1 (de) 4-aryl-4-piperidine (oder -pyrrolidin- oder - hexahydroazepin-) carbinole und heterocyclische analoga davon.
FR2711730B1 (fr) Turbomachine équipée de moyens de pilotage des jeux entre rotor et stator.
ES2146279T3 (es) 1-ciclopropiltetrazolinonas herbicidas.
DE59309355D1 (de) Neue Phospholipidderivate
NO965161L (no) Tiopyridiner som bekjempelsesmiddel mot heliobacter-bakterier
DK0407321T3 (da) Slåmaskine/konditioneringsapparat forsynet med organer til modifikation af den luftstrøm, der frembringes af skæreorganerne
DK53791A (da) Fremgangsmaade til rensning af sugesystemet, f.eks. sugeslangen, i en tandlaegesugeindretning
FR2727965B1 (fr) 4,4'-(phenylenediisopropyl )-bis- (2.6-dialkylphenylisocyanates)
DE29606762U1 (de) Schrittantrieb
NO952255D0 (no) Rotor med skovler for blandemaskin
BR7201977U (pt) Membrana periodontal.
TR26707A (tr) Tikama tertibatinin sizdirmaz hale getirilmesi.
NO883647D0 (no) Fremgangsmaate for fremstilling av en vaksine mot de forskjellige patogene serotyper av gruppe b neisseria meningitidis.