BR9914946A - Composição meningocócica de multicomponentes, vacina compreendendo a referida composição e respectivo processo de preparação - Google Patents

Composição meningocócica de multicomponentes, vacina compreendendo a referida composição e respectivo processo de preparação

Info

Publication number
BR9914946A
BR9914946A BR9914946-0A BR9914946A BR9914946A BR 9914946 A BR9914946 A BR 9914946A BR 9914946 A BR9914946 A BR 9914946A BR 9914946 A BR9914946 A BR 9914946A
Authority
BR
Brazil
Prior art keywords
composition
vaccine
preparation process
meningococcal
respective preparation
Prior art date
Application number
BR9914946-0A
Other languages
English (en)
Inventor
Andrew Robinson
Andrew Richard Gorringe
Michael John Hudson
Karen Margaret Reddin
Original Assignee
Microbiological Res Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10841713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9914946(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Microbiological Res Authority filed Critical Microbiological Res Authority
Publication of BR9914946A publication Critical patent/BR9914946A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçãO MENINGOCóCICA DE MULTICOMPONENTES, VACINA COMPREENDENDO A REFERIDA COMPOSIçãO E RESPECTIVO PROCESSO DE PREPARAçãO''<D> Descreve-se uma composição contendo proteínas de ligação de transferrina A e B (TbpA e TbpB). A composição é adequada para uso em vacinas e para o tratamento de infecção bacteriana gram negativa, particularmente infecção meningocócica, demostrando um amplo espectro de proteção para inúmeros patógenos bacterianos diferentes. Também são descritas composições compreendendo Tbp's e outros componentes, tais como vesículas de membranas externas neisseriais e Cu, Zn-Superóxido Dismutase. Processos para preparação dessas composições e seus usos em vacinação contra doenças são adicionalmente fornecidos.
BR9914946-0A 1998-11-02 1999-11-02 Composição meningocócica de multicomponentes, vacina compreendendo a referida composição e respectivo processo de preparação BR9914946A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9823978.3A GB9823978D0 (en) 1998-11-02 1998-11-02 Multicomponent meningococcal vaccine
PCT/GB1999/003626 WO2000025811A2 (en) 1998-11-02 1999-11-02 Multicomponent meningococcal vaccine

Publications (1)

Publication Number Publication Date
BR9914946A true BR9914946A (pt) 2001-07-10

Family

ID=10841713

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914946-0A BR9914946A (pt) 1998-11-02 1999-11-02 Composição meningocócica de multicomponentes, vacina compreendendo a referida composição e respectivo processo de preparação

Country Status (13)

Country Link
US (2) US6821521B1 (pt)
EP (3) EP1297844A3 (pt)
JP (2) JP2002528515A (pt)
AT (1) ATE242640T1 (pt)
AU (1) AU760858B2 (pt)
BR (1) BR9914946A (pt)
CA (1) CA2349331A1 (pt)
DE (1) DE69908805T3 (pt)
DK (1) DK1126874T5 (pt)
ES (1) ES2197688T5 (pt)
GB (1) GB9823978D0 (pt)
PT (1) PT1126874E (pt)
WO (1) WO2000025811A2 (pt)

Families Citing this family (53)

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GB9823978D0 (en) * 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
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US10967045B2 (en) 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
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EP1322328B1 (en) 2000-07-27 2014-08-20 Children's Hospital & Research Center at Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
EP1961427A3 (en) 2002-08-02 2009-11-04 GlaxoSmithKline Biologicals S.A. Neisserial vaccine compositions comprising a combination of antigens
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DE60335477D1 (de) 2002-10-11 2011-02-03 Novartis Vaccines & Diagnostic Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
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GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
EP2172213B1 (en) 2003-01-30 2013-04-03 Novartis AG Injectable vaccines against multiple meningococcal serogroups
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GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
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GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US7853431B2 (en) 2006-09-29 2010-12-14 Fisher-Rosemount Systems, Inc. On-line monitoring and diagnostics of a process using multivariate statistical analysis
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EP2200642B1 (en) 2007-10-19 2012-04-18 Novartis AG Meningococcal vaccine formulations
AU2009215364B2 (en) 2008-02-21 2014-09-18 Glaxosmithkline Biologicals S.A. Meningococcal fHBP polypeptides
MY150481A (en) 2008-03-03 2014-01-30 Irm Llc Compounds and compositions as tlr activity modulators
AU2009262893B2 (en) * 2008-05-30 2015-05-21 The U.S.A., as represented by The Secretary of the Army, on behalf of Walter Reed Army Institute Of Research Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
EP2367568A2 (en) 2008-12-17 2011-09-28 Novartis AG Meningococcal vaccines including hemoglobin receptor
CA2761916A1 (fr) 2009-05-14 2010-11-18 Sanofi Pasteur Procede pour adjuver le lipopolysaccharide (lps) des bacteries a gram-negatif
US20120156281A1 (en) * 2009-05-14 2012-06-21 Sanofi Pasteur Meningococcal Vaccine Based on Lipooligosaccharide (LOS) and Neisseria Meningitidis Protein
US9517263B2 (en) 2009-06-10 2016-12-13 Glaxosmithkline Biologicals Sa Benzonaphthyridine-containing vaccines
CA2772103A1 (en) 2009-08-27 2011-03-03 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
AU2010288240B2 (en) 2009-08-27 2014-03-27 Novartis Ag Hybrid polypeptides including meningococcal fHBP sequences
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
TWI445708B (zh) 2009-09-02 2014-07-21 Irm Llc 作為ｔｌｒ活性調節劑之化合物及組合物
GB0916557D0 (en) 2009-09-21 2009-10-28 Health Prot Agency Commensal neisserial stress protein complexes
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
JP5960055B2 (ja) 2009-10-27 2016-08-02 ノバルティス アーゲー 改変髄膜炎菌ｆＨＢＰポリペプチド
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG181712A1 (en) 2009-12-15 2012-07-30 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
CN102869378A (zh) 2010-03-10 2013-01-09 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
CA2793510A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
CA2792938C (en) 2010-03-23 2018-07-31 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
WO2012038801A1 (en) 2010-09-21 2012-03-29 National Institute Of Immunology A spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles
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GB201110980D0 (en) 2011-06-28 2011-08-10 Health Prot Agency Neisserial compositions and expression constructs
RU2014135522A (ru) 2012-02-02 2016-03-27 Новартис Аг Промоторы для увеличенной экспрессии белка у менингококка
JP2015524418A (ja) 2012-07-27 2015-08-24 アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 血管内皮細胞への髄膜炎菌の線毛媒介接着の受容体としてのｃｄ１４７
AU2013311702A1 (en) 2012-09-06 2015-02-19 Novartis Ag Combination vaccines with serogroup B meningococcus and D/T/P
CA2940447C (en) 2014-02-28 2023-07-11 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
CN107847532A (zh) * 2015-06-02 2018-03-27 由卫生福利和体育大臣代表的荷兰王国 革兰氏阴性菌外膜囊泡抗原表面展示

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EP1322328B1 (en) * 2000-07-27 2014-08-20 Children's Hospital & Research Center at Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0130123D0 (en) * 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
EP1961427A3 (en) * 2002-08-02 2009-11-04 GlaxoSmithKline Biologicals S.A. Neisserial vaccine compositions comprising a combination of antigens
AU2003288660A1 (en) * 2002-11-15 2004-06-15 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
US20090035328A1 (en) * 2007-08-02 2009-02-05 Dan Granoff fHbp- AND LPXL1-BASED VESICLE VACCINES FOR BROAD SPECTRUM PROTECTION AGAINST DISEASES CAUSED BY NEISSERIA MENINGITIDIS

Also Published As

Publication number Publication date
EP1297844A2 (en) 2003-04-02
GB9823978D0 (en) 1998-12-30
EP1126874B2 (en) 2008-06-25
WO2000025811A3 (en) 2000-10-05
DK1126874T5 (da) 2008-12-01
DE69908805T3 (de) 2008-12-24
CA2349331A1 (en) 2000-05-11
EP1126874A2 (en) 2001-08-29
JP2002528515A (ja) 2002-09-03
PT1126874E (pt) 2003-10-31
ES2197688T5 (es) 2008-12-16
US20090148469A1 (en) 2009-06-11
AU1056900A (en) 2000-05-22
JP2012025774A (ja) 2012-02-09
EP1297844A3 (en) 2004-01-14
WO2000025811A2 (en) 2000-05-11
DE69908805T2 (de) 2004-05-19
DE69908805D1 (de) 2003-07-17
AU760858B2 (en) 2003-05-22
DK1126874T3 (da) 2003-09-29
ES2197688T3 (es) 2004-01-01
US6821521B1 (en) 2004-11-23
ATE242640T1 (de) 2003-06-15
DK1126874T4 (da) 2008-10-13
EP2248535A1 (en) 2010-11-10
EP1126874B1 (en) 2003-06-11

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B25A Requested transfer of rights approved

Owner name: HEALTH PROTECTION AGENCY (UK)

Free format text: TRANSFERIDO DE: MICROBIOLOGICAL RESEARCH AUTHORITY CAMR

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 13, 24 E 25 DA LPI.

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B25A Requested transfer of rights approved

Owner name: THE SECRETARY OF STATE FOR HEALTH (GB)