DK1119564T3 - Aryl-4-fluor-4-(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl-methanon-derivater som agonister for 5-HT1-receptoren - Google Patents

Aryl-4-fluor-4-(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl-methanon-derivater som agonister for 5-HT1-receptoren

Info

Publication number
DK1119564T3
DK1119564T3 DK99970390T DK99970390T DK1119564T3 DK 1119564 T3 DK1119564 T3 DK 1119564T3 DK 99970390 T DK99970390 T DK 99970390T DK 99970390 T DK99970390 T DK 99970390T DK 1119564 T3 DK1119564 T3 DK 1119564T3
Authority
DK
Denmark
Prior art keywords
piperidin
ethylamino
pyridin
fluoro
methyl
Prior art date
Application number
DK99970390T
Other languages
Danish (da)
English (en)
Inventor
Bernard Vacher
Bernard Bonnaud
Wouter Koek
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of DK1119564T3 publication Critical patent/DK1119564T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99970390T 1998-10-09 1999-10-07 Aryl-4-fluor-4-(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl-methanon-derivater som agonister for 5-HT1-receptoren DK1119564T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9812660A FR2784378B1 (fr) 1998-10-09 1998-10-09 Nouveaux derives d'aryl-(4-fluoro-4-[(2-pyridin-2-yl- ethylamino)-methyl]-piperidin-1-yl)-methanone, leur procede de preparation et leur utilisation a titre de medicaments
PCT/FR1999/002401 WO2000021953A1 (fr) 1998-10-09 1999-10-07 Derives d'aryl-{4-fluoro-4-[(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl}-methanone comme agonistes du recepteur 5-ht1

Publications (1)

Publication Number Publication Date
DK1119564T3 true DK1119564T3 (da) 2003-04-07

Family

ID=9531367

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99970390T DK1119564T3 (da) 1998-10-09 1999-10-07 Aryl-4-fluor-4-(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl-methanon-derivater som agonister for 5-HT1-receptoren

Country Status (14)

Country Link
US (1) US6448268B1 (zh)
EP (1) EP1119564B1 (zh)
JP (1) JP2003514764A (zh)
CN (1) CN1160348C (zh)
AT (1) ATE229951T1 (zh)
AU (1) AU761122B2 (zh)
BR (1) BR9914331A (zh)
CA (1) CA2346506C (zh)
DE (1) DE69904626T2 (zh)
DK (1) DK1119564T3 (zh)
ES (1) ES2187215T3 (zh)
FR (1) FR2784378B1 (zh)
WO (1) WO2000021953A1 (zh)
ZA (1) ZA200102942B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2840900B1 (fr) * 2002-06-18 2005-02-25 Pf Medicament Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments
FR2852244B1 (fr) * 2003-03-13 2007-09-07 Pf Medicament Utilisation de derives de pyridin-2-yl-methylamine pour la preparation d'un medicament destine au traitement des symptomes de la douleur chronique d'origine neuropathique ou psychogene
EP3260452A1 (en) * 2016-06-24 2017-12-27 Neurolixis Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-ht1a receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
FR2755967B1 (fr) * 1996-11-21 1999-01-29 Pf Medicament Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
US6448268B1 (en) 2002-09-10
FR2784378A1 (fr) 2000-04-14
EP1119564B1 (fr) 2002-12-18
EP1119564A1 (fr) 2001-08-01
ES2187215T3 (es) 2003-05-16
FR2784378B1 (fr) 2000-12-29
BR9914331A (pt) 2001-06-26
AU5990599A (en) 2000-05-01
ZA200102942B (en) 2002-05-02
WO2000021953A1 (fr) 2000-04-20
DE69904626D1 (en) 2003-01-30
ATE229951T1 (de) 2003-01-15
AU761122B2 (en) 2003-05-29
DE69904626T2 (de) 2003-10-23
CN1325396A (zh) 2001-12-05
CA2346506C (fr) 2009-01-13
JP2003514764A (ja) 2003-04-22
CN1160348C (zh) 2004-08-04
CA2346506A1 (fr) 2000-04-20

Similar Documents

Publication Publication Date Title
ATE433962T1 (de) Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors
NO20026094L (no) Kondenserte azepinderivater og deres anvendelse som antidiuretiske midler
IL155702A0 (en) Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5-ht2 receptor
MX2009002229A (es) Benzotriazoles como moduladores de cinasas.
MA27040A1 (fr) Nucleosides substitues en 4'
UY26754A1 (es) Derivados de la 1, 3, 8, -triaza-spiro (4,5) decan-4-ona
PT1204654E (pt) Benzofurilpiperazinas agonistas do receptor 5-ht2c da serotonina
PA8467101A1 (es) Compuestos 4-(2-ceto-1-benzilimidazolinil)piperidina como agonistas del receptor orli
DE60211223D1 (de) Piperidinderivate als Kalium-Kanal Blockers
ES2188095T3 (es) Carboxamidas heterociclicas.
HK1155146A1 (zh) 作為藥物活性劑的茚衍生物
ATE416157T1 (de) Inhibitoren von integrin alpha-v-beta-6
MA27921A1 (fr) Systemes emulsifiants contenant des derives d'azetidine
IT1312115B1 (it) Composti amorfi e relative composizioni farmaceutiche
DE69708968D1 (de) Arylacrylamidderivate als 5HT1 Agoniste oder Antagoniste
BR0212353A (pt) Composto, composição farmacêutica, e, uso de um composto
PT952154E (pt) N-acil- e n-aroil-aralquilamidas
AP2001002188A0 (en) 5HT1 antagonists for antidepressant therapy.
DK1119564T3 (da) Aryl-4-fluor-4-(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl-methanon-derivater som agonister for 5-HT1-receptoren
ATE253058T1 (de) Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten
GB0202635D0 (en) Formulation containing novel anti-inflammatory androstane derivative
DE60216948D1 (en) 4'-methansulfonylbiphenylderivate als hochselektive cyclooxygenase-2-inhibitoren
MXPA03002532A (es) Nuevos compuestos de indolina, un proceso para su preparacion y composiciones farmaceuticas que los contienen.
AU2000246281A1 (en) Piperidine compounds and process for providing such
YU39603A (sh) Jedinjenja piperazinilpirazina kao antagonisti serotonin 5-ht2 receptora