ATE229951T1 - Aryl-4-fluoro-4-(2-pyridin-2-yl-ethylamino)- methyl)-piperidin-1-yl-methanone derivate als 5- ht1-rezeptor-agonisten - Google Patents

Aryl-4-fluoro-4-(2-pyridin-2-yl-ethylamino)- methyl)-piperidin-1-yl-methanone derivate als 5- ht1-rezeptor-agonisten

Info

Publication number
ATE229951T1
ATE229951T1 AT99970390T AT99970390T ATE229951T1 AT E229951 T1 ATE229951 T1 AT E229951T1 AT 99970390 T AT99970390 T AT 99970390T AT 99970390 T AT99970390 T AT 99970390T AT E229951 T1 ATE229951 T1 AT E229951T1
Authority
AT
Austria
Prior art keywords
ethylamino
fluoro
methyl
piperidine
pyridine
Prior art date
Application number
AT99970390T
Other languages
English (en)
Inventor
Bernard Vacher
Bernard Bonnaud
Wouter Koek
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of ATE229951T1 publication Critical patent/ATE229951T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99970390T 1998-10-09 1999-10-07 Aryl-4-fluoro-4-(2-pyridin-2-yl-ethylamino)- methyl)-piperidin-1-yl-methanone derivate als 5- ht1-rezeptor-agonisten ATE229951T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9812660A FR2784378B1 (fr) 1998-10-09 1998-10-09 Nouveaux derives d'aryl-(4-fluoro-4-[(2-pyridin-2-yl- ethylamino)-methyl]-piperidin-1-yl)-methanone, leur procede de preparation et leur utilisation a titre de medicaments
PCT/FR1999/002401 WO2000021953A1 (fr) 1998-10-09 1999-10-07 Derives d'aryl-{4-fluoro-4-[(2-pyridin-2-yl-ethylamino)-methyl]-piperidin-1-yl}-methanone comme agonistes du recepteur 5-ht1

Publications (1)

Publication Number Publication Date
ATE229951T1 true ATE229951T1 (de) 2003-01-15

Family

ID=9531367

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970390T ATE229951T1 (de) 1998-10-09 1999-10-07 Aryl-4-fluoro-4-(2-pyridin-2-yl-ethylamino)- methyl)-piperidin-1-yl-methanone derivate als 5- ht1-rezeptor-agonisten

Country Status (14)

Country Link
US (1) US6448268B1 (de)
EP (1) EP1119564B1 (de)
JP (1) JP2003514764A (de)
CN (1) CN1160348C (de)
AT (1) ATE229951T1 (de)
AU (1) AU761122B2 (de)
BR (1) BR9914331A (de)
CA (1) CA2346506C (de)
DE (1) DE69904626T2 (de)
DK (1) DK1119564T3 (de)
ES (1) ES2187215T3 (de)
FR (1) FR2784378B1 (de)
WO (1) WO2000021953A1 (de)
ZA (1) ZA200102942B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2840900B1 (fr) * 2002-06-18 2005-02-25 Pf Medicament Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments
FR2852244B1 (fr) * 2003-03-13 2007-09-07 Pf Medicament Utilisation de derives de pyridin-2-yl-methylamine pour la preparation d'un medicament destine au traitement des symptomes de la douleur chronique d'origine neuropathique ou psychogene
EP3260452A1 (de) * 2016-06-24 2017-12-27 Neurolixis Verbindungen zur behandlung von serotoninsensitiven erkrankungen gesteuert durch 5-ht1a rezeptoren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0661266A1 (de) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituierte cyclische Aminverbindungen als 5HT2 Antagonisten
FR2755967B1 (fr) * 1996-11-21 1999-01-29 Pf Medicament Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
US6448268B1 (en) 2002-09-10
FR2784378A1 (fr) 2000-04-14
EP1119564B1 (de) 2002-12-18
EP1119564A1 (de) 2001-08-01
ES2187215T3 (es) 2003-05-16
FR2784378B1 (fr) 2000-12-29
BR9914331A (pt) 2001-06-26
AU5990599A (en) 2000-05-01
ZA200102942B (en) 2002-05-02
WO2000021953A1 (fr) 2000-04-20
DE69904626D1 (en) 2003-01-30
AU761122B2 (en) 2003-05-29
DE69904626T2 (de) 2003-10-23
DK1119564T3 (da) 2003-04-07
CN1325396A (zh) 2001-12-05
CA2346506C (fr) 2009-01-13
JP2003514764A (ja) 2003-04-22
CN1160348C (zh) 2004-08-04
CA2346506A1 (fr) 2000-04-20

Similar Documents

Publication Publication Date Title
ATE433962T1 (de) Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors
ES2188095T3 (es) Carboxamidas heterociclicas.
ATE314383T1 (de) 2-amino-propanol derivate
DE60134874D1 (de) Benzodiazepin-derivate als gamma-secretase inhibitoren
PA8467101A1 (es) Compuestos 4-(2-ceto-1-benzilimidazolinil)piperidina como agonistas del receptor orli
PT1204654E (pt) Benzofurilpiperazinas agonistas do receptor 5-ht2c da serotonina
DE60032524D1 (de) EP4 Rezeptor Ligand und Verwendung gegen neuropatischen Schmerzen, Colon Krebs, HIV und Migräne
SE9702773D0 (sv) Novel compounds
BR0209149A (pt) Ftalazinonas
ATE416157T1 (de) Inhibitoren von integrin alpha-v-beta-6
DE69708968D1 (de) Arylacrylamidderivate als 5HT1 Agoniste oder Antagoniste
ATE498600T1 (de) Inden derivate als pharmazeutika
PT952154E (pt) N-acil- e n-aroil-aralquilamidas
ATE229951T1 (de) Aryl-4-fluoro-4-(2-pyridin-2-yl-ethylamino)- methyl)-piperidin-1-yl-methanone derivate als 5- ht1-rezeptor-agonisten
DE602004018811D1 (de) Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
DE60036558D1 (de) Phthalazinon-derivate als pde 4 hemmer
CY1107287T1 (el) Χρηση της ερυθροποιητινης, καθως και παραγωγων αυτης για τη θεραπεια σχιζοφρενειων και συναφων ψυχωσεων
TR200102205T2 (tr) Anti-konvülsan türevlerinin bulimia nevruza tedavisinde kullanılmaları.
DE60319743D1 (de) Phthalazinderivate als phosphodiesterase-4-hemmer
AU2000246281A1 (en) Piperidine compounds and process for providing such
ATE330671T1 (de) Verwendung von alkyl 3-(n- alkylacetamino)propionat derivaten als feuchthaltemittel
ECSP992845A (es) Compuestos quimicos
YU39603A (sh) Jedinjenja piperazinilpirazina kao antagonisti serotonin 5-ht2 receptora
HUP9800542A2 (hu) Epoxi-azetidinonok, eljárás előállításukra és alkalmazásuk

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1119564

Country of ref document: EP

REN Ceased due to non-payment of the annual fee