DE60211223D1 - Piperidinderivate als Kalium-Kanal Blockers - Google Patents
Piperidinderivate als Kalium-Kanal BlockersInfo
- Publication number
- DE60211223D1 DE60211223D1 DE60211223T DE60211223T DE60211223D1 DE 60211223 D1 DE60211223 D1 DE 60211223D1 DE 60211223 T DE60211223 T DE 60211223T DE 60211223 T DE60211223 T DE 60211223T DE 60211223 D1 DE60211223 D1 DE 60211223D1
- Authority
- DE
- Germany
- Prior art keywords
- channel blockers
- potassium channel
- piperidine derivatives
- formula
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0104251 | 2001-12-14 | ||
SE0104251A SE0104251D0 (sv) | 2001-12-14 | 2001-12-14 | Novel compounds |
PCT/SE2002/002304 WO2003051839A1 (en) | 2001-12-14 | 2002-12-11 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60211223D1 true DE60211223D1 (de) | 2006-06-08 |
DE60211223T2 DE60211223T2 (de) | 2007-04-19 |
Family
ID=20286353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60211223T Expired - Lifetime DE60211223T2 (de) | 2001-12-14 | 2002-12-11 | Piperidinderivate als Kalium-Kanal Blockers |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1499590B8 (de) |
AT (1) | ATE325095T1 (de) |
AU (1) | AU2002359122A1 (de) |
CA (1) | CA2487365C (de) |
CY (1) | CY1106132T1 (de) |
DE (1) | DE60211223T2 (de) |
DK (1) | DK1499590T3 (de) |
ES (1) | ES2261773T3 (de) |
HK (1) | HK1071134A1 (de) |
MY (1) | MY128924A (de) |
PT (1) | PT1499590E (de) |
SE (1) | SE0104251D0 (de) |
TW (1) | TWI255185B (de) |
WO (1) | WO2003051839A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
US8017762B2 (en) | 2003-04-17 | 2011-09-13 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
US7851615B2 (en) | 2003-04-17 | 2010-12-14 | Alnylam Pharmaceuticals, Inc. | Lipophilic conjugated iRNA agents |
US7723509B2 (en) | 2003-04-17 | 2010-05-25 | Alnylam Pharmaceuticals | IRNA agents with biocleavable tethers |
US8796436B2 (en) | 2003-04-17 | 2014-08-05 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
EP2669377A3 (de) | 2003-04-17 | 2015-10-14 | Alnylam Pharmaceuticals Inc. | Modifizierte iRNA-Wirkstoffe |
EP1912942A1 (de) * | 2005-08-01 | 2008-04-23 | AstraZeneca AB | Neue piperidinderivate als für die behandlung von atemwegserkrankungen geeignete modulatoren des chemokinrezeptors |
TW200734305A (en) * | 2005-08-02 | 2007-09-16 | Astrazeneca Ab | New salt III |
TW200738635A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200738634A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
BRPI0615064A2 (pt) * | 2005-08-26 | 2011-05-03 | Astrazeneca Ab | combinação de compostos que pode ser usada no tratamento de doenças respiratórias, especialmente, doença pulmonar obstrutiva crÈnica (dpoc) e asma |
TW200744612A (en) * | 2005-08-26 | 2007-12-16 | Astrazeneca Ab | New combination |
ES2340604T3 (es) | 2005-12-21 | 2010-06-07 | F. Hoffmann-La Roche Ag | Lineas celulares estables que expresan herg. |
US20080064884A1 (en) * | 2006-05-10 | 2008-03-13 | Astrazeneca Ab | Novel Process 1 |
GB0702456D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
US20110136843A1 (en) * | 2007-02-23 | 2011-06-09 | Tomas Eriksson | Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma |
WO2008121065A1 (en) * | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | Novel pyrrolidine derivatives as antagonists of the chemokine receptor |
JP2011507593A (ja) | 2007-12-20 | 2011-03-10 | アストラゼネカ・アクチエボラーグ | 粉末854を脱凝集解体する装置ならびに方法 |
US9289565B2 (en) | 2008-10-08 | 2016-03-22 | Astrazeneca Ab | Inhaler with indexing linked to movement of cover |
TW201036957A (en) | 2009-02-20 | 2010-10-16 | Astrazeneca Ab | Novel salt 628 |
NZ597009A (en) | 2009-07-01 | 2014-05-30 | Astrazeneca Ab | Dispenser and method for entraining powder in an airflow |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
WO2011073662A1 (en) | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
CA2788015A1 (en) | 2010-02-10 | 2011-08-18 | Astrazeneca Uk Limited | Process for providing a filled canister for an inhaler |
US20140000601A1 (en) | 2010-07-21 | 2014-01-02 | Astrazeneca Ab | Inhaler |
CN103118726B (zh) | 2010-07-21 | 2015-07-22 | 阿斯利康(瑞典)有限公司 | 吸入器 |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
WO2012163848A1 (en) | 2011-05-27 | 2012-12-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of crohn's disease |
GB201115874D0 (en) | 2011-09-14 | 2011-10-26 | Astrazeneca Ab | Inhaler |
GB201115870D0 (en) | 2011-09-14 | 2011-10-26 | Astrazeneca Ab | Inhaler |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5300399A1 (es) * | 2000-02-25 | 2003-07-31 | Astrazeneca Ab | Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen |
-
2001
- 2001-12-14 SE SE0104251A patent/SE0104251D0/xx unknown
-
2002
- 2002-12-11 WO PCT/SE2002/002304 patent/WO2003051839A1/en not_active Application Discontinuation
- 2002-12-11 DE DE60211223T patent/DE60211223T2/de not_active Expired - Lifetime
- 2002-12-11 AT AT02793633T patent/ATE325095T1/de not_active IP Right Cessation
- 2002-12-11 AU AU2002359122A patent/AU2002359122A1/en not_active Abandoned
- 2002-12-11 PT PT02793633T patent/PT1499590E/pt unknown
- 2002-12-11 EP EP02793633A patent/EP1499590B8/de not_active Expired - Lifetime
- 2002-12-11 DK DK02793633T patent/DK1499590T3/da active
- 2002-12-11 ES ES02793633T patent/ES2261773T3/es not_active Expired - Lifetime
- 2002-12-11 CA CA002487365A patent/CA2487365C/en not_active Expired - Fee Related
- 2002-12-13 TW TW091136138A patent/TWI255185B/zh not_active IP Right Cessation
- 2002-12-13 MY MYPI20024681A patent/MY128924A/en unknown
-
2005
- 2005-05-09 HK HK05103887A patent/HK1071134A1/xx not_active IP Right Cessation
-
2006
- 2006-07-27 CY CY20061101043T patent/CY1106132T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2261773T3 (es) | 2006-11-16 |
PT1499590E (pt) | 2006-08-31 |
DK1499590T3 (da) | 2006-07-31 |
CA2487365A1 (en) | 2003-06-26 |
WO2003051839A1 (en) | 2003-06-26 |
MY128924A (en) | 2007-02-28 |
EP1499590A1 (de) | 2005-01-26 |
DE60211223T2 (de) | 2007-04-19 |
ATE325095T1 (de) | 2006-06-15 |
CA2487365C (en) | 2009-06-16 |
CY1106132T1 (el) | 2011-06-08 |
TWI255185B (en) | 2006-05-21 |
EP1499590B1 (de) | 2006-05-03 |
TW200409631A (en) | 2004-06-16 |
HK1071134A1 (en) | 2005-07-08 |
SE0104251D0 (sv) | 2001-12-14 |
EP1499590B8 (de) | 2006-08-02 |
AU2002359122A1 (en) | 2003-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |