DK110384A - Kondenserede imidazolforbindelser - Google Patents

Kondenserede imidazolforbindelser Download PDF

Info

Publication number
DK110384A
DK110384A DK110384A DK110384A DK110384A DK 110384 A DK110384 A DK 110384A DK 110384 A DK110384 A DK 110384A DK 110384 A DK110384 A DK 110384A DK 110384 A DK110384 A DK 110384A
Authority
DK
Denmark
Prior art keywords
imidazole compounds
condensed imidazole
condensed
compounds
imidazole
Prior art date
Application number
DK110384A
Other languages
Danish (da)
English (en)
Other versions
DK110384D0 (da
Inventor
Ikuo Ueda
Masayuki Kato
Masanobu Nagano
Atsushi Akahane
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK110384D0 publication Critical patent/DK110384D0/da
Publication of DK110384A publication Critical patent/DK110384A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK110384A 1983-03-22 1984-02-27 Kondenserede imidazolforbindelser DK110384A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838307865A GB8307865D0 (en) 1983-03-22 1983-03-22 Benzimidazole derivatives

Publications (2)

Publication Number Publication Date
DK110384D0 DK110384D0 (da) 1984-02-27
DK110384A true DK110384A (da) 1984-09-23

Family

ID=10540007

Family Applications (1)

Application Number Title Priority Date Filing Date
DK110384A DK110384A (da) 1983-03-22 1984-02-27 Kondenserede imidazolforbindelser

Country Status (13)

Country Link
US (1) US4563455A (xx)
EP (1) EP0125756A3 (xx)
JP (1) JPS59176277A (xx)
KR (1) KR840008016A (xx)
AU (1) AU2587384A (xx)
DK (1) DK110384A (xx)
ES (1) ES530810A0 (xx)
FI (1) FI841082A (xx)
GB (1) GB8307865D0 (xx)
GR (1) GR79774B (xx)
IL (1) IL71310A0 (xx)
NO (1) NO841106L (xx)
ZA (1) ZA841393B (xx)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK585485A (da) * 1984-12-18 1986-08-08 Utsuka Pharm Co Ltd Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse
US4728741A (en) * 1985-01-08 1988-03-01 Smithkline Beckman Corporation 1-substituted-2-mercapto benzimidazole compounds and intermediates
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
CA1327010C (en) * 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
US5433959A (en) 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
US6749864B2 (en) * 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
GB8612796D0 (en) * 1986-05-27 1986-07-02 Fbc Ltd Fungicides
US4772600A (en) * 1986-06-09 1988-09-20 A. H. Robins Company, Inc. Fused imidazoheterocyclic compounds and pharmaceutical compositions
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
DE3634066A1 (de) * 1986-10-07 1988-04-21 Boehringer Mannheim Gmbh Neue 5-alkylbenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
DE69011645T2 (de) * 1989-11-29 1995-01-12 Toa Eiyo Ltd Cycloheptenopyridinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Antiulkusmitteln.
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
NO306992B1 (no) * 1993-01-28 2000-01-24 Takeda Chemical Industries Ltd Quinolinderivater, farmasoeytiske preparater inneholdende forbindelsene og anvendelsen av forbindelsene
KR0156327B1 (ko) * 1995-07-12 1998-11-16 김종인 벤즈 또는 피리도이미다졸 유도체
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
JP3256513B2 (ja) 1998-02-11 2002-02-12 ファイザー製薬株式会社 ベンゾイミダゾールシクロオキシゲナーゼ−2阻害剤
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
BR0308785A (pt) * 2002-03-27 2005-01-11 Altana Pharma Ag Derivados de alcoxipiridina
JP2006518724A (ja) 2003-02-25 2006-08-17 アルタナ ファルマ アクチエンゲゼルシャフト イミダゾ(4,5)キノリン誘導体およびno−シンターゼ阻害剤としてのそれらの使用
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
DE10344897A1 (de) * 2003-09-26 2005-04-21 Bosch Gmbh Robert Ventil zur Steuerung einer Verbindung in einem Hochdruckflüssigkeitssystem, insbesondere einer Kraftstoffeinspritzeinrichtung für eine Brennkraftmaschine
BRPI0415038A (pt) 2003-10-01 2006-12-12 Altana Pharma Ag derivados de imidazo (4,5-b) piridina como inibidores sem ser da sintase que podem ser induzidos
EA200600609A1 (ru) * 2003-10-01 2006-10-27 Алтана Фарма Аг Производные имидазопиридина в качестве ингибиторов индуцируемой no-синтазы
EA200600601A1 (ru) * 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
WO2005030770A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
RS20060196A (xx) * 2003-10-01 2008-08-07 Altana Pharma Ag., Imidazopiridinski derivati kao inhibitori inducibilne no-sintaze
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
PE20070427A1 (es) * 2005-08-30 2007-04-21 Novartis Ag Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
FR2949469A1 (fr) * 2009-08-25 2011-03-04 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
TWI481607B (zh) 2009-12-17 2015-04-21 Lundbeck & Co As H 作為pde10a酵素抑制劑的2-芳基咪唑衍生物
TWI485151B (zh) 2009-12-17 2015-05-21 Lundbeck & Co As H 作為pde10a酵素抑制劑之雜芳香族苯基咪唑衍生物
TWI487705B (zh) 2009-12-17 2015-06-11 Lundbeck & Co As H 作為pde10a酵素抑制劑之雜芳香族芳基三唑衍生物
TW201206935A (en) 2010-07-16 2012-02-16 Lundbeck & Co As H Triazolo-and pyrazoloquinazoline derivatives as PDE10A enzyme inhibitor
JO3089B1 (ar) 2010-11-19 2017-03-15 H Lundbeck As مشتقات ايميدازول كمثبطات لانزيمات pde10a

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH262959A (de) * 1944-12-21 1949-07-31 Ciba Geigy Verfahren zur Herstellung des neuen a-(Benzthiazyl-(2))-B-(benzimidazyl-(2))-äthylens.
BE569485A (xx) * 1957-07-17
FR1476560A (fr) * 1965-08-05 1967-04-14 Chimetron Sarl Thiazolylalcoyl-2 benzimidazoles et thiadiazolylalcoyl-2 benzimidazoles alpha-halogénés ou alpha-aminés
FR2104717A1 (en) * 1970-09-28 1972-04-21 Dynachim Sarl Organophosphorus pesticides stabilised with benzimidazole derivs - - for controlling insects and internal parasites of animals
US3897432A (en) * 1971-04-21 1975-07-29 Merck & Co Inc Substituted benzimidazole derivatives
SU455104A1 (ru) * 1971-08-11 1974-12-30 Ордена Трудового Красного Знамени Институт Тонкой Органической Химии Им. А.Л.Мнджояна Способ получени 2-метил-3-( -алкил -бензимидазолил-2")-этилиндолов
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4294837A (en) * 1980-03-28 1981-10-13 Sterling Drug Inc. 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use
GB2101115A (en) * 1980-10-23 1983-01-12 Pfizer Ltd Thromboxane synthetase inhibitors

Also Published As

Publication number Publication date
ES8506001A1 (es) 1985-06-16
ES530810A0 (es) 1985-06-16
GB8307865D0 (en) 1983-04-27
EP0125756A3 (en) 1987-04-08
IL71310A0 (en) 1984-06-29
ZA841393B (en) 1984-10-31
FI841082A (fi) 1984-09-23
EP0125756A2 (en) 1984-11-21
AU2587384A (en) 1984-09-27
GR79774B (xx) 1984-10-31
US4563455A (en) 1986-01-07
NO841106L (no) 1984-09-24
DK110384D0 (da) 1984-02-27
FI841082A0 (fi) 1984-03-19
KR840008016A (ko) 1984-12-12
JPS59176277A (ja) 1984-10-05

Similar Documents

Publication Publication Date Title
DK110384D0 (da) Kondenserede imidazolforbindelser
DOP1983004163A (es) Compuestos biciclicos
DK281883A (da) Heterocycliske forbindelser
DK573482A (da) Tetrahydrophthalimidforbindelser
DK583684D0 (da) Kemiske forbindelser
FR2544384B1 (fr) Turbomoteur compound perfectionne
DK442283A (da) Polyvinylpyrrolidongel forbindsstoffer
DK372385A (da) Imidazolderivater
DK54883A (da) Heterocykliske forbindelser
DK247783D0 (da) Heterocykliske forbindelser
DK416284A (da) Azolforbindelser
DK356684D0 (da) Tripamidinklusionsforbindelser
DK17385D0 (da) Oxadiazinonforbindelser
IT1154570B (it) Composti triarilboranoisociano-metallici
DK163662C (da) N-chlorsulfonyl-2-oxindol-1-carboxamid-forbindelser
DK148585D0 (da) Imidazolderivater
DK36584A (da) Imidazolderivater
TR22132A (tr) Pestisid benzoiluere bilesikleri
DK335684A (da) Azolforbindelser
DK325784D0 (da) Kemiske forbindelser
DK267383D0 (da) Imidazolforbindelser
DE3379655D1 (de) Azetidinone compounds
DK462784D0 (da) Triazolforbindelser
NO831890L (no) Imidazol forbindelser
DK376084A (da) Phosphordithioforbindelser

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment