DK1102781T3 - Nye cofaktorer for methyltransferaser - Google Patents
Nye cofaktorer for methyltransferaserInfo
- Publication number
- DK1102781T3 DK1102781T3 DK99938363T DK99938363T DK1102781T3 DK 1102781 T3 DK1102781 T3 DK 1102781T3 DK 99938363 T DK99938363 T DK 99938363T DK 99938363 T DK99938363 T DK 99938363T DK 1102781 T3 DK1102781 T3 DK 1102781T3
- Authority
- DK
- Denmark
- Prior art keywords
- methyltransferases
- cofactors
- novel
- novel cofactors
- adenosyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/048—Pyridine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/125—Methyl transferase, i.e. methylase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98114201 | 1998-07-29 | ||
| PCT/EP1999/005405 WO2000006587A1 (en) | 1998-07-29 | 1999-07-28 | New cofactors for methyltransferases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1102781T3 true DK1102781T3 (da) | 2004-04-05 |
Family
ID=8232369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99938363T DK1102781T3 (da) | 1998-07-29 | 1999-07-28 | Nye cofaktorer for methyltransferaser |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6875750B1 (de) |
| EP (1) | EP1102781B1 (de) |
| JP (1) | JP2002521488A (de) |
| AT (1) | ATE256696T1 (de) |
| CA (1) | CA2338721C (de) |
| DE (1) | DE69913705T2 (de) |
| DK (1) | DK1102781T3 (de) |
| ES (1) | ES2211138T3 (de) |
| PT (1) | PT1102781E (de) |
| WO (1) | WO2000006587A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2281205A1 (en) | 1997-02-12 | 1998-08-13 | Eugene Y. Chan | Methods and products for analyzing polymers |
| US6927065B2 (en) | 1999-08-13 | 2005-08-09 | U.S. Genomics, Inc. | Methods and apparatus for characterization of single polymers |
| EP1354064A2 (de) | 2000-12-01 | 2003-10-22 | Visigen Biotechnologies, Inc. | Enzymatische nukleinsäuresynthese: zusammensetzungen und verfahren, um die zuverlässigkeit des monomereinbaus zu erhöhen |
| AU2002318336A1 (en) * | 2001-06-08 | 2002-12-23 | U.S. Genomics, Inc. | Methods and products for analyzing nucleic acids based on methylation status |
| WO2005121361A2 (en) * | 2004-06-14 | 2005-12-22 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Sequence-specific detection of methylation in biomolecules |
| ATE482396T1 (de) * | 2004-12-28 | 2010-10-15 | Advanced Life Science Inst Inc | Blockierter enzymsondenkomplex |
| US7465544B2 (en) | 2006-01-11 | 2008-12-16 | Wisconsin Alumni Research Foundation | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use |
| US20100137154A1 (en) * | 2008-12-01 | 2010-06-03 | Ach Robert A | Genome analysis using a methyltransferase |
| LT5708B (en) | 2009-04-02 | 2011-01-25 | Biotechnologijos Inst | Derivatization of biomolecules by covalent coupling of non-cofactor compounds using methyltransferases |
| EP2577275A1 (de) | 2010-06-04 | 2013-04-10 | Katholieke Universiteit Leuven K.U. Leuven R&D | Optisches mapping von genomischer dna |
| GB201119903D0 (en) | 2011-11-17 | 2011-12-28 | Univ Vilnius | Nucleic acid production and sequence analysis |
| CN106029909B (zh) | 2014-02-18 | 2021-02-02 | 生物纳米基因公司 | 测定核酸结构信息的改进方法 |
| EP3497239A4 (de) | 2016-08-10 | 2020-02-26 | Ramot at Tel-Aviv University Ltd. | Analyse des methylierungsstatus und kopienzahl |
-
1999
- 1999-07-28 DE DE69913705T patent/DE69913705T2/de not_active Expired - Lifetime
- 1999-07-28 AT AT99938363T patent/ATE256696T1/de active
- 1999-07-28 JP JP2000562384A patent/JP2002521488A/ja active Pending
- 1999-07-28 DK DK99938363T patent/DK1102781T3/da active
- 1999-07-28 ES ES99938363T patent/ES2211138T3/es not_active Expired - Lifetime
- 1999-07-28 CA CA002338721A patent/CA2338721C/en not_active Expired - Lifetime
- 1999-07-28 WO PCT/EP1999/005405 patent/WO2000006587A1/en active IP Right Grant
- 1999-07-28 PT PT99938363T patent/PT1102781E/pt unknown
- 1999-07-28 EP EP99938363A patent/EP1102781B1/de not_active Expired - Lifetime
- 1999-07-28 US US09/744,641 patent/US6875750B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2338721A1 (en) | 2000-02-10 |
| ES2211138T3 (es) | 2004-07-01 |
| ATE256696T1 (de) | 2004-01-15 |
| WO2000006587A1 (en) | 2000-02-10 |
| EP1102781B1 (de) | 2003-12-17 |
| DE69913705T2 (de) | 2004-09-30 |
| CA2338721C (en) | 2008-11-18 |
| JP2002521488A (ja) | 2002-07-16 |
| US6875750B1 (en) | 2005-04-05 |
| PT1102781E (pt) | 2004-04-30 |
| DE69913705D1 (de) | 2004-01-29 |
| EP1102781A1 (de) | 2001-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2182234T3 (es) | Inhibidores de metaloproteasa. | |
| DE60225671D1 (de) | Pharmazeutisch wirksame piperidinderivate | |
| DK1102781T3 (da) | Nye cofaktorer for methyltransferaser | |
| ATE360627T1 (de) | Pyrrolidindion-substituierte piperidin- phthalazone als pde4-inhibitoren | |
| DK0923554T3 (da) | N-Benzylpiperidin- og tetrahydropyridinderivater | |
| DK1070056T3 (da) | Phthalazinon-PDE III/IV-inhibitorer | |
| BR0207278A (pt) | Derivados de ftalazinona-piperidina como inibidores de pde4 | |
| PT1001930E (pt) | Derivados de n-hidroxiformamida como inibidores de metaloproteinases de matriz | |
| EA200000826A1 (ru) | Галоидированные производные амидиноаминокислот, применимые в качестве ингибиторов no-синтазы | |
| SE0103710D0 (sv) | Compounds | |
| ATE288922T1 (de) | Bestimmte heteroaryl substituierte thiol inhibitoren von endothelin wechselnden enzymen | |
| EA200000628A1 (ru) | Ингибиторы металлопротеаз матрикса | |
| BR0115996A (pt) | Sulfamidotienopirimidinas | |
| BRPI0415285A (pt) | derivados de aminoalcanol | |
| BRPI0415034A (pt) | derivados de aminopiridina como inibidores de não-sintase induzìveis | |
| BR9912307A (pt) | Inibidores fkbp | |
| ATE320422T1 (de) | Metalloproteinase inhibitoren | |
| ATE403741T1 (de) | 7-alkoxycumarinverbindungen als cytochrom p450- substrate | |
| TR200402470T4 (tr) | Aminometil-aril-sikloheksanol-türevlerinin enzimatik rasemat ayırma yöntemi. | |
| EA200600609A1 (ru) | Производные имидазопиридина в качестве ингибиторов индуцируемой no-синтазы | |
| PA8478901A1 (es) | Isoquinolinas | |
| PT1104419E (pt) | Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao | |
| AP2001002047A0 (en) | Isoquinoliness as urokinase inhibitors. | |
| DK1140932T3 (da) | Derivater af benzo-1,8-naphtyridin | |
| ATE238781T1 (de) | Verwendung von katecholderivaten als proteinaseinhibitoren |