DK1073723T3 - STE20-relaterede proteinkinaser - Google Patents

STE20-relaterede proteinkinaser

Info

Publication number
DK1073723T3
DK1073723T3 DK99918539T DK99918539T DK1073723T3 DK 1073723 T3 DK1073723 T3 DK 1073723T3 DK 99918539 T DK99918539 T DK 99918539T DK 99918539 T DK99918539 T DK 99918539T DK 1073723 T3 DK1073723 T3 DK 1073723T3
Authority
DK
Denmark
Prior art keywords
ste20
protein kinases
nucleic acid
acid molecules
molecules encoding
Prior art date
Application number
DK99918539T
Other languages
Danish (da)
English (en)
Inventor
Gregory Plowman
Ricardo Martinez
David Whyte
Original Assignee
Sugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen Inc filed Critical Sugen Inc
Application granted granted Critical
Publication of DK1073723T3 publication Critical patent/DK1073723T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99918539T 1998-04-14 1999-04-13 STE20-relaterede proteinkinaser DK1073723T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8178498P 1998-04-14 1998-04-14

Publications (1)

Publication Number Publication Date
DK1073723T3 true DK1073723T3 (da) 2006-01-02

Family

ID=22166386

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99918539T DK1073723T3 (da) 1998-04-14 1999-04-13 STE20-relaterede proteinkinaser

Country Status (10)

Country Link
US (5) US6680170B2 (enExample)
EP (1) EP1073723B1 (enExample)
JP (1) JP2002522009A (enExample)
AT (1) ATE302269T1 (enExample)
AU (1) AU3642499A (enExample)
CA (1) CA2369172A1 (enExample)
DE (1) DE69926742T2 (enExample)
DK (1) DK1073723T3 (enExample)
ES (1) ES2248997T3 (enExample)
WO (1) WO1999053036A2 (enExample)

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US7078182B1 (en) * 1998-04-14 2006-07-18 Board Of Regents, The University Of Texas System TAO protein kinase polypeptides and methods of use therefor
US6013500A (en) 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase
WO2000015805A1 (en) * 1998-09-10 2000-03-23 Smithkline Beecham P.L.C. Use of protein kinase kiaa0551 as pharmaceutical
AU2654900A (en) * 1999-02-19 2000-09-04 Mcmaster University A caspase activated protein kinase
WO2000060062A2 (en) * 1999-04-01 2000-10-12 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
US6558903B1 (en) * 1999-06-30 2003-05-06 Millennium Pharmaceuticals, Inc. Kinases and uses thereof
WO2001009316A1 (en) * 1999-07-29 2001-02-08 Helix Research Institute Novel genes encoding protein kinase/protein phosphatase
US20030104622A1 (en) * 1999-09-01 2003-06-05 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
US6861239B1 (en) 1999-09-20 2005-03-01 New York University Genes and polynucleotides associated with ultraviolet radiation-mediated skin damage and uses thereof
EP1244774A2 (en) * 1999-11-15 2002-10-02 Pharmacia Italia S.p.A. Pak5 a member of the p21-activated kinase (pak) protein family, nucleic acids and methods related to the same
EP1254214A2 (en) * 2000-01-25 2002-11-06 Sugen, Inc. Human protein kinases and protein kinase-like enzymes
US20040072184A1 (en) * 2000-09-20 2004-04-15 Thillainathan Yoganathan Cancer associated protein kinases and their uses
WO2002055738A2 (en) * 2001-01-12 2002-07-18 Incyte Genomics Inc Molecules for disease detection and treatment
US7265214B2 (en) * 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
JP2005518198A (ja) 2001-12-28 2005-06-23 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Ｐａｋ５関連の組成物及び方法
EP1539956B1 (en) * 2002-07-05 2011-01-26 Sugen, Inc. GEF-H1b: BIOMARKERS, COMPLEXES, ASSAYS AND THERAPEUTIC USES THEREOF
GB0220770D0 (en) * 2002-09-06 2002-10-16 Ares Trading Sa Proteins
SI2055786T1 (sl) * 2002-11-27 2011-04-29 Sugen Inc Fosfospecifična PAK-protitelesa in diagnostični kompleti
WO2004056982A2 (en) * 2002-12-23 2004-07-08 Devgen Nv Kinase sequences
GB2396615A (en) * 2002-12-23 2004-06-30 Devgen Nv Kinase sequences useful for developing compounds for the prevention and/or treatment of metabolic diseases
US20040242461A1 (en) * 2003-04-08 2004-12-02 Schneider Michael D. Modulators of telomere stability
ES2398394T3 (es) * 2003-08-13 2013-03-15 Novartis Vaccines And Diagnostics, Inc. Reactivos peptídicos específicos de prión
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
JP4989225B2 (ja) * 2003-09-25 2012-08-01 コーリー ファーマシューティカル グループ，インコーポレイテッド 核酸親油性接合体
WO2005111234A2 (en) * 2004-05-12 2005-11-24 Sugen, Inc. Methods of using zc1 and zc3 kinase substrate phosphorylation as biomarkers
US20090130774A1 (en) * 2005-01-13 2009-05-21 David Peretz Elisa assays using prion-specific peptide reagents
WO2006076497A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Osplation of pathogenic prions
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
WO2007030804A1 (en) * 2005-09-09 2007-03-15 Novartis Ag Prion-specific peptoid reagents
JP2011520108A (ja) * 2008-04-30 2011-07-14 ノバルティス アーゲー 病原性配座異性体についてのアッセイ
KR101219395B1 (ko) * 2010-07-15 2013-01-11 전자부품연구원 리튬이차전지용 양극재료 및 그의 제조방법

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US4343940A (en) 1979-02-13 1982-08-10 Mead Johnson & Company Anti-tumor quinazoline compounds
EP0031237B1 (en) 1979-12-19 1984-10-17 National Research Development Corporation Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
DE3611194A1 (de) 1986-04-04 1987-10-08 Bayer Ag Cancerostatisches mittel
US5217999A (en) 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
DE3920029C2 (de) 1988-06-30 1999-05-20 Clariant Finance Bvi Ltd Farbstoffe zum Färben von Kunststoffen
ES2064101T3 (es) 1990-04-02 1995-01-16 Pfizer Compuestos de acido bencilfosfonico inhibidores de la quinasa de tirosina.
US5302606A (en) 1990-04-16 1994-04-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase
DE69222637T2 (de) 1991-05-10 1998-02-26 Rhone Poulenc Rorer Int Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase
JPH06503095A (ja) 1991-05-29 1994-04-07 ファイザー・インコーポレーテッド 三環式ポリヒドロキシ系のチロシンキナーゼ阻害薬
NZ243082A (en) 1991-06-28 1995-02-24 Ici Plc 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
US5298422A (en) 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
AU661533B2 (en) 1992-01-20 1995-07-27 Astrazeneca Ab Quinazoline derivatives
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EP0654024A1 (en) 1992-08-06 1995-05-24 Warner-Lambert Company 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties
US5330992A (en) 1992-10-23 1994-07-19 Sterling Winthrop Inc. 1-cyclopropyl-4-pyridyl-quinolinones
US5366889A (en) * 1992-11-30 1994-11-22 The General Hospital Corporation DNA encoding a protein-coupled receptor kinase
GB9226855D0 (en) 1992-12-23 1993-02-17 Erba Carlo Spa Vinylene-azaindole derivatives and process for their preparation
GB9501567D0 (en) 1995-01-26 1995-03-15 Pharmacia Spa Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors
WO1997042212A1 (en) 1996-05-07 1997-11-13 The General Hospital Corporation Sok-1 and methods of use
WO1998015635A2 (en) 1996-10-04 1998-04-16 Connaught Laboratories Limited Treatment of cancer using a recombinant poxvirus containing a nucleic acid sequence encoding a cytokine
AU8296698A (en) * 1997-07-08 1999-02-08 Cadus Pharmaceutical Corporation (kds) protein kinase molecules and uses related thereto
AU8778698A (en) * 1997-08-11 1999-03-01 Ontogeny, Inc. Serine/threonine kinase, and uses related thereto
GB9719920D0 (en) * 1997-09-19 1997-11-19 Zeneca Ltd Human Ste20-Like Stress Activated Serine/Threonine Kinase
GB9726851D0 (en) * 1997-12-19 1998-02-18 Zeneca Ltd Human signal transduction serine/threonine kinase
US6013500A (en) * 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase

Also Published As

Publication number Publication date
US20050142625A1 (en) 2005-06-30
EP1073723B1 (en) 2005-08-17
ES2248997T3 (es) 2006-03-16
ATE302269T1 (de) 2005-09-15
DE69926742T2 (de) 2006-06-14
WO1999053036A9 (en) 2000-02-17
EP1073723A2 (en) 2001-02-07
US20030050230A1 (en) 2003-03-13
US20040224323A1 (en) 2004-11-11
AU3642499A (en) 1999-11-01
US20070072261A1 (en) 2007-03-29
CA2369172A1 (en) 1999-10-21
WO1999053036A3 (en) 2000-05-11
JP2002522009A (ja) 2002-07-23
DE69926742D1 (de) 2005-09-22
US6680170B2 (en) 2004-01-20
WO1999053036A2 (en) 1999-10-21
US6656716B1 (en) 2003-12-02

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