DK1071809T3 - Multiparameter FACS test til påvisning af ændringer i cellulære parametre - Google Patents
Multiparameter FACS test til påvisning af ændringer i cellulære parametreInfo
- Publication number
- DK1071809T3 DK1071809T3 DK99917563T DK99917563T DK1071809T3 DK 1071809 T3 DK1071809 T3 DK 1071809T3 DK 99917563 T DK99917563 T DK 99917563T DK 99917563 T DK99917563 T DK 99917563T DK 1071809 T3 DK1071809 T3 DK 1071809T3
- Authority
- DK
- Denmark
- Prior art keywords
- detect changes
- cellular parameters
- cell
- facs test
- multiparameter
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4718—Lipocortins
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/062,330 US6897031B1 (en) | 1998-04-17 | 1998-04-17 | Multiparameter FACS assays to detect alterations in exocytosis |
| US09/157,748 US6461813B2 (en) | 1998-09-21 | 1998-09-21 | Multiparameter FACS assays to detect alterations in cell cycle regulation |
| PCT/US1999/008345 WO1999054494A2 (en) | 1998-04-17 | 1999-04-16 | Multiparameter facs assays to detect alterations in cellular parameters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1071809T3 true DK1071809T3 (da) | 2003-12-01 |
Family
ID=26742137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99917563T DK1071809T3 (da) | 1998-04-17 | 1999-04-16 | Multiparameter FACS test til påvisning af ændringer i cellulære parametre |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP1071809B1 (de) |
| JP (1) | JP4511033B2 (de) |
| CN (1) | CN100334227C (de) |
| AT (1) | ATE248226T1 (de) |
| AU (1) | AU3565499A (de) |
| CA (1) | CA2325597C (de) |
| DE (1) | DE69910756T2 (de) |
| DK (1) | DK1071809T3 (de) |
| ES (1) | ES2207203T3 (de) |
| NZ (1) | NZ508120A (de) |
| PT (1) | PT1071809E (de) |
| WO (1) | WO1999054494A2 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030215798A1 (en) | 1997-06-16 | 2003-11-20 | Diversa Corporation | High throughput fluorescence-based screening for novel enzymes |
| US7090976B2 (en) | 1999-11-10 | 2006-08-15 | Rigel Pharmaceuticals, Inc. | Methods and compositions comprising Renilla GFP |
| US6651008B1 (en) | 1999-05-14 | 2003-11-18 | Cytokinetics, Inc. | Database system including computer code for predictive cellular bioinformatics |
| US6743576B1 (en) | 1999-05-14 | 2004-06-01 | Cytokinetics, Inc. | Database system for predictive cellular bioinformatics |
| US7151847B2 (en) | 2001-02-20 | 2006-12-19 | Cytokinetics, Inc. | Image analysis of the golgi complex |
| DE60135652D1 (de) * | 2000-06-01 | 2008-10-16 | Pasteur Institut | Chimäres GPF-Aequorin als bioluminiszenter Ca++ Marker auf Einzelzellniveau |
| US7218764B2 (en) | 2000-12-04 | 2007-05-15 | Cytokinetics, Inc. | Ploidy classification method |
| US7016787B2 (en) | 2001-02-20 | 2006-03-21 | Cytokinetics, Inc. | Characterizing biological stimuli by response curves |
| US6956961B2 (en) | 2001-02-20 | 2005-10-18 | Cytokinetics, Inc. | Extracting shape information contained in cell images |
| US7393656B2 (en) | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
| US7381535B2 (en) | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
| DE60233574D1 (de) | 2001-07-10 | 2009-10-15 | Univ R | Verfahren und zusammensetzungen zum nachweis des aktivierungszustands multipler proteine in einzelzellen |
| WO2005010677A2 (en) | 2003-07-18 | 2005-02-03 | Cytokinetics, Inc. | Characterizing biological stimuli by response curves |
| US7235353B2 (en) | 2003-07-18 | 2007-06-26 | Cytokinetics, Inc. | Predicting hepatotoxicity using cell based assays |
| US20050014217A1 (en) | 2003-07-18 | 2005-01-20 | Cytokinetics, Inc. | Predicting hepatotoxicity using cell based assays |
| CN1860363B (zh) * | 2003-08-28 | 2011-12-28 | 赛路拉公司 | 用于在微流通道网络中使用光学开关将细胞分类的方法和设备 |
| JP4454998B2 (ja) * | 2003-09-29 | 2010-04-21 | 株式会社ニコン | 細胞観察装置および細胞観察方法 |
| US7323318B2 (en) | 2004-07-15 | 2008-01-29 | Cytokinetics, Inc. | Assay for distinguishing live and dead cells |
| JP4557685B2 (ja) * | 2004-11-15 | 2010-10-06 | 独立行政法人理化学研究所 | 蛍光蛋白質 |
| EP1943332A4 (de) | 2005-10-14 | 2011-04-13 | Medimmune Inc | Zellpräsentation von antikörperbibliotheken |
| FR2902440B1 (fr) * | 2006-06-19 | 2008-08-29 | Univ Paris Curie | Methode de detection et de denombrement des cellules en cytodierese |
| US20090098594A1 (en) | 2007-08-21 | 2009-04-16 | Nodality, Inc. | Methods for diagnosis prognosis and methods of treatment |
| EP2304436A1 (de) | 2008-07-10 | 2011-04-06 | Nodality, Inc. | Diagnose-, prognose- und behandlungsverfahren |
| US8309306B2 (en) | 2008-11-12 | 2012-11-13 | Nodality, Inc. | Detection composition |
| US9459246B2 (en) | 2009-09-08 | 2016-10-04 | Nodality, Inc. | Induced intercellular communication |
| US20110193950A1 (en) * | 2010-02-09 | 2011-08-11 | Stephen Liye Chen | Application of microscopic linear array scanner for measuring rate of change of live organisms |
| CA2806294C (en) * | 2010-07-28 | 2018-06-12 | Canvax Biotech Sl | Novel ultrasensitive cell based sensors and uses thereof |
| US9005909B2 (en) | 2011-01-06 | 2015-04-14 | Rigel Pharmaceuticals, Inc. | Whole blood assay for measuring AMPK activation |
| US9766224B2 (en) | 2015-03-25 | 2017-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis using secondary ion mass spectrometry |
| CA3020542A1 (en) | 2016-04-11 | 2017-10-19 | Board Of Regents, The University Of Texas System | Methods and compositions for detecting single t cell receptor affinity and sequence |
| CN110412179A (zh) * | 2018-04-26 | 2019-11-05 | 缪荣明 | 一种液相色谱检测颗粒酶a的方法 |
| EP3880838A4 (de) | 2018-11-15 | 2022-11-02 | The Board of Trustees of the Leland Stanford Junior University | Zusammensetzungen und verfahren zur prognose und klassifizierung von präeklampsie |
| WO2021079656A1 (ja) * | 2019-10-24 | 2021-04-29 | 国立大学法人千葉大学 | 細胞内脂質代謝酵素活性測定法及び細胞内脂質代謝酵素活性測定用物質 |
| EP4343775A1 (de) | 2022-09-22 | 2024-03-27 | SurgeCare | Verfahren zur bestimmung eines medizinischen ergebnisses für eine person, zugehöriges elektronisches system und computerprogramm |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304720A (en) * | 1980-04-30 | 1981-12-08 | Merck & Co., Inc. | Fluorescein esters and ethers and the preparation thereof |
| US5266464A (en) * | 1988-02-10 | 1993-11-30 | Ict Pharmaceuticals, Inc. | Method of screening for protein inhibitors and activators |
| AU6179690A (en) * | 1989-08-09 | 1991-03-11 | Michael Reese Hospital And Medical Center | Method for detection and treatment of multiple drug-resistant tumor cells and useful colchicine derivative probes |
| US5264341A (en) * | 1989-08-30 | 1993-11-23 | Eli Lilly And Company | Selective cloning for high monoclonal antibody secreting hybridomas |
| JPH04252128A (ja) * | 1990-08-03 | 1992-09-08 | Systemix Inc | 免疫化された宿主における変性された異種移植器官系 |
| US5723288A (en) * | 1994-05-06 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor |
| GB9506466D0 (en) * | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
| GB9516138D0 (en) * | 1995-08-05 | 1995-10-04 | Medical Res Council | Improvements in or relating to methods of screening substances |
| US20030215798A1 (en) * | 1997-06-16 | 2003-11-20 | Diversa Corporation | High throughput fluorescence-based screening for novel enzymes |
| BR9712410A (pt) * | 1996-10-18 | 1999-10-19 | Genentech Inc | Anticorpo isolado, composição, ácido nucleico, vetor, célula hospedeira, método para fazer um anticorpo anti-erbb2, método para a determinação da presença de erbb2, kit, método paa a indução da morte celular e artigo manufaturado |
-
1999
- 1999-04-16 NZ NZ508120A patent/NZ508120A/en not_active IP Right Cessation
- 1999-04-16 AT AT99917563T patent/ATE248226T1/de active
- 1999-04-16 JP JP2000544822A patent/JP4511033B2/ja not_active Expired - Lifetime
- 1999-04-16 EP EP99917563A patent/EP1071809B1/de not_active Expired - Lifetime
- 1999-04-16 ES ES99917563T patent/ES2207203T3/es not_active Expired - Lifetime
- 1999-04-16 WO PCT/US1999/008345 patent/WO1999054494A2/en active IP Right Grant
- 1999-04-16 AU AU35654/99A patent/AU3565499A/en not_active Abandoned
- 1999-04-16 DE DE69910756T patent/DE69910756T2/de not_active Expired - Lifetime
- 1999-04-16 DK DK99917563T patent/DK1071809T3/da active
- 1999-04-16 CN CNB998070904A patent/CN100334227C/zh not_active Expired - Lifetime
- 1999-04-16 CA CA2325597A patent/CA2325597C/en not_active Expired - Lifetime
- 1999-04-16 EP EP03019052A patent/EP1363127A3/de not_active Withdrawn
- 1999-04-16 PT PT99917563T patent/PT1071809E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69910756D1 (de) | 2003-10-02 |
| EP1071809B1 (de) | 2003-08-27 |
| PT1071809E (pt) | 2004-01-30 |
| ATE248226T1 (de) | 2003-09-15 |
| WO1999054494A2 (en) | 1999-10-28 |
| EP1363127A3 (de) | 2004-03-24 |
| JP2002512362A (ja) | 2002-04-23 |
| EP1071809A2 (de) | 2001-01-31 |
| ES2207203T3 (es) | 2004-05-16 |
| CN100334227C (zh) | 2007-08-29 |
| CA2325597A1 (en) | 1999-10-28 |
| WO1999054494A3 (en) | 2000-02-10 |
| CN1304489A (zh) | 2001-07-18 |
| JP4511033B2 (ja) | 2010-07-28 |
| DE69910756T2 (de) | 2004-07-08 |
| EP1363127A2 (de) | 2003-11-19 |
| NZ508120A (en) | 2003-10-31 |
| CA2325597C (en) | 2010-09-21 |
| AU3565499A (en) | 1999-11-08 |
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