DK1027047T3 - Eprosartan-arginyl-ladningsneutraliseringskompleks og fremgangsmåde til dets fremstilling og formulering - Google Patents

Eprosartan-arginyl-ladningsneutraliseringskompleks og fremgangsmåde til dets fremstilling og formulering

Info

Publication number
DK1027047T3
DK1027047T3 DK98939213T DK98939213T DK1027047T3 DK 1027047 T3 DK1027047 T3 DK 1027047T3 DK 98939213 T DK98939213 T DK 98939213T DK 98939213 T DK98939213 T DK 98939213T DK 1027047 T3 DK1027047 T3 DK 1027047T3
Authority
DK
Denmark
Prior art keywords
eprosartan
formulation
preparation
charge neutralization
arginyl charge
Prior art date
Application number
DK98939213T
Other languages
Danish (da)
English (en)
Inventor
Gopadi M Venkatesh
Manga R Gudipati
John M Jushchyshyn
Nageswara R Palepu
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DK1027047T3 publication Critical patent/DK1027047T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK98939213T 1997-08-06 1998-08-04 Eprosartan-arginyl-ladningsneutraliseringskompleks og fremgangsmåde til dets fremstilling og formulering DK1027047T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5499097P 1997-08-06 1997-08-06
PCT/US1998/016245 WO1999007365A1 (en) 1997-08-06 1998-08-04 Eprosartan arginyl charge-neutralization-complex and a process for its production and formulation

Publications (1)

Publication Number Publication Date
DK1027047T3 true DK1027047T3 (da) 2007-01-29

Family

ID=21994861

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98939213T DK1027047T3 (da) 1997-08-06 1998-08-04 Eprosartan-arginyl-ladningsneutraliseringskompleks og fremgangsmåde til dets fremstilling og formulering

Country Status (27)

Country Link
EP (1) EP1027047B1 (hu)
JP (1) JP4463975B2 (hu)
KR (1) KR100508044B1 (hu)
CN (1) CN1276724A (hu)
AR (1) AR015930A1 (hu)
AT (1) ATE341325T1 (hu)
AU (1) AU739295B2 (hu)
BR (1) BR9811926A (hu)
CA (1) CA2299470C (hu)
CO (1) CO4960666A1 (hu)
CY (1) CY1105851T1 (hu)
CZ (1) CZ296274B6 (hu)
DE (1) DE69836095T2 (hu)
DK (1) DK1027047T3 (hu)
ES (1) ES2273433T3 (hu)
HK (1) HK1031688A1 (hu)
HU (1) HUP0201624A3 (hu)
IL (1) IL134378A (hu)
NO (1) NO317771B1 (hu)
NZ (1) NZ502644A (hu)
PL (1) PL198875B1 (hu)
PT (1) PT1027047E (hu)
SA (1) SA98190592B1 (hu)
TR (1) TR200000350T2 (hu)
TW (1) TW570921B (hu)
WO (1) WO1999007365A1 (hu)
ZA (1) ZA987018B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA991922B (en) * 1998-03-11 1999-09-13 Smithkline Beecham Corp Novel compositions of eprosartan.
RU2239454C2 (ru) * 1999-04-28 2004-11-10 Такеда Кемикал Индастриз, Лтд. Фармацевтическая композиция для предотвращения, лечения или ингибирования развития простой ретинопатии и препролиферирующей ретинопатии
EA009983B1 (ru) 2003-01-31 2008-04-28 Дайити Санкио Компани, Лимитед Лекарственное средство для профилактики и лечения артериосклероза и гипертензии
NO323391B1 (no) 2005-09-28 2007-04-23 Hts Hans Torgersen & Sonn As Barnepose
US20100278909A1 (en) * 2007-06-06 2010-11-04 Dexcel Ltd. Process for forming solid oral dosage forms of angiotensin ii receptor antagonists
JP5476782B2 (ja) * 2009-04-21 2014-04-23 大正製薬株式会社 アルギニン含有錠剤の製造方法
JP5446716B2 (ja) * 2009-10-21 2014-03-19 大正製薬株式会社 アルギニン及びカルニチン含有錠剤の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185351A (en) * 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
JP3214856B2 (ja) * 1990-12-14 2001-10-02 スミスクライン・ビーチャム・コーポレイション イミダゾリル−アルケン酸
DE10399008I1 (de) * 1990-12-14 2006-06-08 Smithkline Beecham Corp Angiotensin-II-Rezeptor blockierende Zusammensetzungen
US5187159A (en) * 1991-10-07 1993-02-16 Merck & Co., Inc. Angiotensin II antagonists incorporating a substituted 1,3-benzodioxole or 1,3-benzodithiole
DE4208052A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Imidazolyl substituierte phenylessigsaeureamide
FR2688781B1 (fr) * 1992-03-23 1994-07-01 Sanofi Elf Imidazolines n-substituees par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
DE4210787A1 (de) * 1992-04-01 1993-10-07 Bayer Ag Cycloalkyl- und Heterocyclyl substituierte Imidazolylpropensäurederivate
JPH0841053A (ja) * 1994-07-28 1996-02-13 Nkk Corp ヘテロアリールアルキル基を有するピリミジン誘導体及 び該誘導体を有効成分として含有するアンジオテンシン ii拮抗剤
US5645839A (en) * 1995-06-07 1997-07-08 Trustees Of Boston University Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
CN1209129A (zh) * 1995-12-14 1999-02-24 麦克公司 促性腺激素释放激素的拮抗药

Also Published As

Publication number Publication date
KR20010022582A (ko) 2001-03-26
DE69836095T2 (de) 2007-04-12
NO317771B1 (no) 2004-12-13
IL134378A (en) 2004-02-19
ATE341325T1 (de) 2006-10-15
AR015930A1 (es) 2001-05-30
IL134378A0 (en) 2001-04-30
CZ296274B6 (cs) 2006-02-15
HUP0201624A3 (en) 2003-03-28
AU8768898A (en) 1999-03-01
NO20000577D0 (no) 2000-02-04
CO4960666A1 (es) 2000-09-25
JP2001513498A (ja) 2001-09-04
PT1027047E (pt) 2007-01-31
CN1276724A (zh) 2000-12-13
TR200000350T2 (tr) 2000-12-21
EP1027047A4 (en) 2002-09-18
CA2299470C (en) 2010-01-26
BR9811926A (pt) 2000-08-22
PL198875B1 (pl) 2008-07-31
CY1105851T1 (el) 2011-02-02
PL341562A1 (en) 2001-04-23
SA98190592B1 (ar) 2006-06-20
KR100508044B1 (ko) 2005-08-17
EP1027047B1 (en) 2006-10-04
WO1999007365A1 (en) 1999-02-18
CZ2000406A3 (cs) 2000-09-13
HUP0201624A2 (hu) 2002-12-28
DE69836095D1 (de) 2006-11-16
CA2299470A1 (en) 1999-02-18
TW570921B (en) 2004-01-11
HK1031688A1 (en) 2001-06-22
ES2273433T3 (es) 2007-05-01
JP4463975B2 (ja) 2010-05-19
EP1027047A1 (en) 2000-08-16
AU739295B2 (en) 2001-10-11
NZ502644A (en) 2002-03-01
NO20000577L (no) 2000-02-29
ZA987018B (en) 1999-02-08

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