DK0975971T3 - Fremgangsmåder til påvisning af celleapoptose - Google Patents

Fremgangsmåder til påvisning af celleapoptose

Info

Publication number
DK0975971T3
DK0975971T3 DK97946547T DK97946547T DK0975971T3 DK 0975971 T3 DK0975971 T3 DK 0975971T3 DK 97946547 T DK97946547 T DK 97946547T DK 97946547 T DK97946547 T DK 97946547T DK 0975971 T3 DK0975971 T3 DK 0975971T3
Authority
DK
Denmark
Prior art keywords
methods
apoptosis
cell apoptosis
detection
detecting cell
Prior art date
Application number
DK97946547T
Other languages
Danish (da)
English (en)
Inventor
Robert Siman
Sheryl L Meyer
Donna Bozyczko-Coyne
Ratan Venkatraman Bhat
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Application granted granted Critical
Publication of DK0975971T3 publication Critical patent/DK0975971T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK97946547T 1996-11-15 1997-11-13 Fremgangsmåder til påvisning af celleapoptose DK0975971T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3096196P 1996-11-15 1996-11-15
US08/967,625 US6048703A (en) 1996-11-15 1997-11-12 Methods for detecting cell apoptosis

Publications (1)

Publication Number Publication Date
DK0975971T3 true DK0975971T3 (da) 2006-07-03

Family

ID=26706638

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97946547T DK0975971T3 (da) 1996-11-15 1997-11-13 Fremgangsmåder til påvisning af celleapoptose

Country Status (9)

Country Link
US (2) US6048703A (xx)
EP (1) EP0975971B1 (xx)
AT (1) ATE320006T1 (xx)
AU (1) AU5169998A (xx)
CA (1) CA2270866A1 (xx)
DE (1) DE69735436T2 (xx)
DK (1) DK0975971T3 (xx)
HK (1) HK1026739A1 (xx)
WO (1) WO1998021590A1 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
DE69937835T2 (de) * 1998-09-24 2009-01-02 Promega Corp., Madison Antikörper für apoptosemarker und anwendungsverfahren
EP1173486A1 (en) * 1999-04-15 2002-01-23 Merck Frosst Canada & Co. Antibodies that recognize app cleaved by caspases and methods of use
US6482411B1 (en) * 1999-08-27 2002-11-19 Board Of Regents, The University Of Texas System Methods of reducing bone loss with CD40 ligand
ATE311595T1 (de) * 2000-07-21 2005-12-15 Evotec Ag Verfahren zur detektion der apoptose durch ermittlung von cytochrom c als apoptosespezifischem marker, der durch zelluläre ausschüttungsvorgänge ins extrazelluläre medium abgegeben wird
AU2002361642A1 (en) * 2001-11-16 2003-06-10 The University Of Tennessee Research Corporation Recombinant antibody fusion proteins and methods for detection of apoptotic cells
US7541150B2 (en) * 2002-04-08 2009-06-02 University Of Louisville Research Foundation, Inc Method for the diagnosis and prognosis of malignant diseases
US7357928B2 (en) * 2002-04-08 2008-04-15 University Of Louisville Research Foundation, Inc. Method for the diagnosis and prognosis of malignant diseases
JP2005530515A (ja) * 2002-06-26 2005-10-13 ユニヴァーシティー オヴ ルイスヴィル リサーチ ファウンデイション インコーポレイテッド アポトーシスの検出方法
US8492107B2 (en) * 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
ES2367311T3 (es) * 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
EP1745149A4 (en) 2004-04-15 2008-08-06 Univ Florida NEURO-PROTEINS USED AS BIOMARKERS TO DETECT NERVOUS SYSTEM AND OTHER NEUROLOGICAL DISORDERS
EP2236153A3 (en) 2005-01-25 2012-08-22 Five Prime Therapeutics, Inc. Compositons and methods for treating cardiac conditions
US8379197B2 (en) * 2006-01-05 2013-02-19 Chemimage Corporation Spectroscopic systems and methods for classifying and pharmaceutically treating cells
TWI429658B (zh) 2006-06-07 2014-03-11 Bioalliance Cv 辨認癌症細胞上表現的ｃｄ４３與ｃｅａ之含碳水化合物抗原決定區的抗體及其使用方法
WO2008021211A2 (en) * 2006-08-10 2008-02-21 Fred Hutchinson Cancer Research Center Compositions and methods for modulating apoptosis in cells over-expressing bcl-2 family member proteins
AU2008338313B2 (en) 2007-12-18 2014-01-16 Bioalliance C.V. Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same
WO2009088837A2 (en) * 2007-12-31 2009-07-16 The University Of Louisville Research Foundation, Inc. Methods and products to target, capture and characterize stem cells
CA2733990C (en) * 2008-08-11 2018-12-11 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
WO2011041731A2 (en) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Method of inhibiting bcl-2-related survival proteins
WO2011041737A2 (en) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Gain-of-function bcl-2 inhibitors
WO2011062997A2 (en) 2009-11-17 2011-05-26 Musc Foundation For Research Development Human monoclonal antibodies to human nucleolin
EP2714094B1 (en) 2011-06-02 2016-02-24 The University of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles
WO2016179394A1 (en) 2015-05-05 2016-11-10 Malik Mohammad Tariq Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08511690A (ja) * 1993-06-24 1996-12-10 ザ・ジェネラル・ホスピタル・コーポレーション プログラムされた細胞死遺伝子及びタンパク質
US5536639A (en) * 1994-03-25 1996-07-16 Cephalon, Inc. Methods for detecting calpain activation by detection of calpain activated spectrin breakdown products
US5605826A (en) * 1994-06-10 1997-02-25 Panorama Research, Inc. 24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
US6288037B1 (en) * 1996-01-29 2001-09-11 Basf Aktiengesellschaft Substrates and inhibitors for cysteine protease ICH-1

Also Published As

Publication number Publication date
EP0975971A4 (en) 2002-09-25
US7256252B1 (en) 2007-08-14
EP0975971B1 (en) 2006-03-08
CA2270866A1 (en) 1998-05-22
AU5169998A (en) 1998-06-03
EP0975971A1 (en) 2000-02-02
DE69735436D1 (de) 2006-05-04
ATE320006T1 (de) 2006-03-15
DE69735436T2 (de) 2006-10-26
HK1026739A1 (en) 2000-12-22
US6048703A (en) 2000-04-11
WO1998021590A1 (en) 1998-05-22

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