ATE320006T1 - Methode zum nachweis von zell-apoptose - Google Patents

Methode zum nachweis von zell-apoptose

Info

Publication number
ATE320006T1
ATE320006T1 AT97946547T AT97946547T ATE320006T1 AT E320006 T1 ATE320006 T1 AT E320006T1 AT 97946547 T AT97946547 T AT 97946547T AT 97946547 T AT97946547 T AT 97946547T AT E320006 T1 ATE320006 T1 AT E320006T1
Authority
AT
Austria
Prior art keywords
apoptosis
methods
detection
cell apoptosis
detecting cell
Prior art date
Application number
AT97946547T
Other languages
English (en)
Inventor
Robert Siman
Donna Bozyczko-Coyne
Sheryl L Meyer
Ratan Venkatraman Bhat
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Application granted granted Critical
Publication of ATE320006T1 publication Critical patent/ATE320006T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97946547T 1996-11-15 1997-11-13 Methode zum nachweis von zell-apoptose ATE320006T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3096196P 1996-11-15 1996-11-15
US08/967,625 US6048703A (en) 1996-11-15 1997-11-12 Methods for detecting cell apoptosis

Publications (1)

Publication Number Publication Date
ATE320006T1 true ATE320006T1 (de) 2006-03-15

Family

ID=26706638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97946547T ATE320006T1 (de) 1996-11-15 1997-11-13 Methode zum nachweis von zell-apoptose

Country Status (9)

Country Link
US (2) US6048703A (de)
EP (1) EP0975971B1 (de)
AT (1) ATE320006T1 (de)
AU (1) AU5169998A (de)
CA (1) CA2270866A1 (de)
DE (1) DE69735436T2 (de)
DK (1) DK0975971T3 (de)
HK (1) HK1026739A1 (de)
WO (1) WO1998021590A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
ATE382148T1 (de) 1998-09-24 2008-01-15 Promega Corp Antikörper für apoptosemarker und anwendungsverfahren
EP1173486A1 (de) * 1999-04-15 2002-01-23 Merck Frosst Canada & Co. Antikörper, die durch caspase gespaltenes app erkennen und verfahren ihrer anwendung
WO2001016180A2 (en) * 1999-08-27 2001-03-08 Board Of Regents, The University Of Texas System Cd40 agonist compositions and methods of use
EP1301786B1 (de) * 2000-07-21 2005-11-30 Evotec AG Verfahren zur detektion der apoptose durch ermittlung von cytochrom c als apoptosespezifischem marker, der durch zelluläre ausschüttungsvorgänge ins extrazelluläre medium abgegeben wird
AU2002361642A1 (en) * 2001-11-16 2003-06-10 The University Of Tennessee Research Corporation Recombinant antibody fusion proteins and methods for detection of apoptotic cells
US7357928B2 (en) 2002-04-08 2008-04-15 University Of Louisville Research Foundation, Inc. Method for the diagnosis and prognosis of malignant diseases
US7541150B2 (en) * 2002-04-08 2009-06-02 University Of Louisville Research Foundation, Inc Method for the diagnosis and prognosis of malignant diseases
CA2489520A1 (en) * 2002-06-26 2004-01-08 University Of Louisville Research Foundation, Inc. A method for the detection of apoptosis
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
EP2207033B1 (de) 2004-04-15 2014-06-18 University of Florida Research Foundation, Inc. Neuralproteine als Biomarker für Verletzungen des Nervensystems und anderen neuralen Störungen
JP4885122B2 (ja) * 2004-04-15 2012-02-29 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 癌、器官傷害、および筋肉リハビリテーション／運動過剰訓練についての診断の生物マーカーとしてのタンパク質分解マーカー
CA2590338A1 (en) 2005-01-25 2006-08-03 Five Prime Therapeutics, Inc. Compositions and methods for treating cardiac conditions
US8379197B2 (en) * 2006-01-05 2013-02-19 Chemimage Corporation Spectroscopic systems and methods for classifying and pharmaceutically treating cells
HUE043255T2 (hu) * 2006-06-07 2019-08-28 Bioalliance Cv Antitestek, amelyek felismernek ráksejteken expresszált CD43-on és CEA-n jelenlévõ, szénhidrátot tartalmazó epitópot, és eljárások alkalmazásukra
WO2008021211A2 (en) * 2006-08-10 2008-02-21 Fred Hutchinson Cancer Research Center Compositions and methods for modulating apoptosis in cells over-expressing bcl-2 family member proteins
TWI439545B (zh) 2007-12-18 2014-06-01 Bioalliance Cv 辨別癌症細胞表現之ｃｅａ與ｃｄ－４３上含醣表位的抗體與其應用方法
WO2009088837A2 (en) * 2007-12-31 2009-07-16 The University Of Louisville Research Foundation, Inc. Methods and products to target, capture and characterize stem cells
AU2009282117B2 (en) 2008-08-11 2016-05-12 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
WO2011041731A2 (en) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Method of inhibiting bcl-2-related survival proteins
WO2011041737A2 (en) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Gain-of-function bcl-2 inhibitors
WO2011062997A2 (en) 2009-11-17 2011-05-26 Musc Foundation For Research Development Human monoclonal antibodies to human nucleolin
PL3446714T3 (pl) 2011-06-02 2021-11-22 University Of Louisville Research Foundation, Inc. Nanocząstki sprzężone z cząsteczką skierowaną przeciwko nukleolinie
US10857237B2 (en) 2015-05-05 2020-12-08 University Of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and MRI and/or X-ray contrast agents
JP2020500508A (ja) 2016-10-28 2020-01-16 バンヤン・バイオマーカーズ・インコーポレーテッド ユビキチンｃ末端ヒドロラーゼｌ１（ｕｃｈ−ｌ１）およびグリア線維酸性タンパク質（ｇｆａｐ）に対する抗体および関連する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08511690A (ja) * 1993-06-24 1996-12-10 ザ・ジェネラル・ホスピタル・コーポレーション プログラムされた細胞死遺伝子及びタンパク質
US5536639A (en) * 1994-03-25 1996-07-16 Cephalon, Inc. Methods for detecting calpain activation by detection of calpain activated spectrin breakdown products
US5605826A (en) * 1994-06-10 1997-02-25 Panorama Research, Inc. 24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
US6288037B1 (en) * 1996-01-29 2001-09-11 Basf Aktiengesellschaft Substrates and inhibitors for cysteine protease ICH-1

Also Published As

Publication number Publication date
EP0975971B1 (de) 2006-03-08
CA2270866A1 (en) 1998-05-22
DE69735436T2 (de) 2006-10-26
EP0975971A4 (de) 2002-09-25
WO1998021590A1 (en) 1998-05-22
DK0975971T3 (da) 2006-07-03
HK1026739A1 (en) 2000-12-22
AU5169998A (en) 1998-06-03
DE69735436D1 (de) 2006-05-04
US7256252B1 (en) 2007-08-14
EP0975971A1 (de) 2000-02-02
US6048703A (en) 2000-04-11

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