DK0975334T3 - Biologisk nedbrydelige mikropartikler til langvarig frigivelse af terapeutiske midler - Google Patents

Biologisk nedbrydelige mikropartikler til langvarig frigivelse af terapeutiske midler

Info

Publication number
DK0975334T3
DK0975334T3 DK98918424T DK98918424T DK0975334T3 DK 0975334 T3 DK0975334 T3 DK 0975334T3 DK 98918424 T DK98918424 T DK 98918424T DK 98918424 T DK98918424 T DK 98918424T DK 0975334 T3 DK0975334 T3 DK 0975334T3
Authority
DK
Denmark
Prior art keywords
long
therapeutic agents
term release
biodegradable microparticles
relates
Prior art date
Application number
DK98918424T
Other languages
Danish (da)
English (en)
Inventor
Subodh Shah
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/843,975 external-priority patent/US6020004A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK0975334T3 publication Critical patent/DK0975334T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK98918424T 1997-04-17 1998-04-17 Biologisk nedbrydelige mikropartikler til langvarig frigivelse af terapeutiske midler DK0975334T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/843,975 US6020004A (en) 1997-04-17 1997-04-17 Biodegradable microparticles for the sustained delivery of therapeutic drugs
US6166598A 1998-04-16 1998-04-16
PCT/US1998/007856 WO1998046212A1 (fr) 1997-04-17 1998-04-17 Microparticules biodegradables pour administration soutenue de medicaments therapeutiques

Publications (1)

Publication Number Publication Date
DK0975334T3 true DK0975334T3 (da) 2004-01-19

Family

ID=26741350

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98918424T DK0975334T3 (da) 1997-04-17 1998-04-17 Biologisk nedbrydelige mikropartikler til langvarig frigivelse af terapeutiske midler

Country Status (11)

Country Link
EP (1) EP0975334B1 (fr)
JP (1) JP2002514215A (fr)
AT (1) ATE252375T1 (fr)
AU (1) AU7134898A (fr)
CA (1) CA2287534C (fr)
DE (1) DE69819145T2 (fr)
DK (1) DK0975334T3 (fr)
ES (1) ES2205481T3 (fr)
HK (1) HK1022265A1 (fr)
PT (1) PT975334E (fr)
WO (1) WO1998046212A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100354270B1 (ko) 1993-11-19 2003-02-11 알커메스 컨트롤드 테라포이틱스 인코퍼레이티드 Ii 마이크로캡슐화된3-피페리디닐-치환된1,2-벤즈이속사졸및1,2-벤즈이소티아졸
US6291013B1 (en) 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles
WO2001030320A1 (fr) * 1999-10-22 2001-05-03 Amgen Inc. Microparticules biodegradables contenant une nouvelle proteine stimulant l'erythropoietine
US7029700B2 (en) 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
ATE462413T1 (de) * 2000-01-14 2010-04-15 Univ Brown Res Found Verfahren zur herstellung von mikronisierte gefriergetrocknete partikeln
EP2316490A3 (fr) 2000-10-31 2012-02-01 PR Pharmaceuticals, Inc. Methodes et compositions pour améliorer l'administration de molécules bioactives
AU2003231082A1 (en) * 2002-05-02 2003-11-17 Pr Pharmaceuticals, Inc. Controlled release compositions of estradiol metabolites
EP1829529A1 (fr) * 2002-05-03 2007-09-05 PR Pharmaceuticals, Inc. Compositions à libération contrôlée de métabolites d'éstradiol
EP2599502B1 (fr) 2003-04-11 2017-03-01 Antriabio, Inc. Procédé de préparation de conjugués de protéines spécifiques de site
WO2005112894A1 (fr) 2004-05-12 2005-12-01 Baxter International Inc. Production et administration de microsphères d’acide nucléique
PT1758558E (pt) 2004-05-12 2013-12-05 Baxter Healthcare Sa Microesferas contendo oligonucleótidos, sua utilização para o fabrico de um medicamento para o tratamento de diabetes do tipo 1
EP1679065A1 (fr) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Formulation destinée à la libération contrôlée d'interferone par un copolymère bloc PEGT/PBT
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
CN105168146A (zh) 2006-08-04 2015-12-23 巴克斯特国际公司 预防和/或逆转新发作自身免疫糖尿病的基于微球的组合物
US8808747B2 (en) 2007-04-17 2014-08-19 Baxter International Inc. Nucleic acid microparticles for pulmonary delivery
WO2009135854A2 (fr) * 2008-05-06 2009-11-12 Glaxo Group Limited Encapsulation d’agents biologiquement actifs
EP2299990A1 (fr) * 2008-06-09 2011-03-30 Boehringer Ingelheim International GmbH Nouvelles particules à principe actif incorporé pour inhalation
KR20100037389A (ko) * 2008-10-01 2010-04-09 연세대학교 산학협력단 다중 약물방출조절이 가능한 솔리드 마이크로구조체 및 이의 제조방법
US10363281B2 (en) 2016-07-18 2019-07-30 Tissuegen, Inc. Methods and compositions for maintaining the conformation and structural integrity of biomolecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058915A (ja) * 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd 薬物含有脂質小胞体製剤
JP2653255B2 (ja) * 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
WO1996022786A1 (fr) * 1995-01-23 1996-08-01 Takeda Chemical Industries, Ltd. Preparation a diffusion prolongee et son emploi

Also Published As

Publication number Publication date
ES2205481T3 (es) 2004-05-01
CA2287534A1 (fr) 1998-10-22
EP0975334A1 (fr) 2000-02-02
WO1998046212A1 (fr) 1998-10-22
ATE252375T1 (de) 2003-11-15
EP0975334B1 (fr) 2003-10-22
PT975334E (pt) 2004-03-31
HK1022265A1 (en) 2000-08-04
AU7134898A (en) 1998-11-11
JP2002514215A (ja) 2002-05-14
CA2287534C (fr) 2004-12-28
DE69819145T2 (de) 2004-08-19
DE69819145D1 (de) 2003-11-27

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