DK0929577T3 - Stabiliserede proteinholdige protease-inhibitorer og varianter deraf - Google Patents

Stabiliserede proteinholdige protease-inhibitorer og varianter deraf

Info

Publication number
DK0929577T3
DK0929577T3 DK97941633T DK97941633T DK0929577T3 DK 0929577 T3 DK0929577 T3 DK 0929577T3 DK 97941633 T DK97941633 T DK 97941633T DK 97941633 T DK97941633 T DK 97941633T DK 0929577 T3 DK0929577 T3 DK 0929577T3
Authority
DK
Denmark
Prior art keywords
variants
protease inhibitors
proteinaceous protease
stabilized
stabilized proteinaceous
Prior art date
Application number
DK97941633T
Other languages
English (en)
Inventor
Paul Elliott Correa
Charles Winston Saunders
Michael Laskowski Jr
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of DK0929577T3 publication Critical patent/DK0929577T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK97941633T 1996-09-24 1997-09-23 Stabiliserede proteinholdige protease-inhibitorer og varianter deraf DK0929577T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2694496P 1996-09-24 1996-09-24
PCT/US1997/016355 WO1998013387A1 (en) 1996-09-24 1997-09-23 Stabilized proteinaceous protease inhibitors and variants thereof

Publications (1)

Publication Number Publication Date
DK0929577T3 true DK0929577T3 (da) 2003-10-06

Family

ID=21834705

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97941633T DK0929577T3 (da) 1996-09-24 1997-09-23 Stabiliserede proteinholdige protease-inhibitorer og varianter deraf

Country Status (10)

Country Link
US (1) US6579698B1 (da)
EP (1) EP0929577B1 (da)
JP (1) JP2000506394A (da)
AR (1) AR009819A1 (da)
AT (1) ATE242270T1 (da)
BR (1) BR9711540A (da)
CA (1) CA2266323A1 (da)
DE (1) DE69722639T2 (da)
DK (1) DK0929577T3 (da)
WO (1) WO1998013387A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004500007A (ja) * 1998-06-26 2004-01-08 ザ、プロクター、エンド、ギャンブル、カンパニー ストレプトマイセス属のサブチリシンインヒビターの安定化変異体
BR9911891A (pt) * 1998-07-07 2001-03-27 Procter & Gamble Proteases fundidas com variantes de inibidor de subtilisina de streptomyces
US20040038845A1 (en) * 2000-08-21 2004-02-26 Pedersen Poul Erik Method for production of a protease-inhibitor complex
US20080255058A1 (en) * 2004-09-29 2008-10-16 Kao Corporation Composition for Oral Cavity
US7759299B2 (en) * 2006-07-24 2010-07-20 Ecolab Inc. Warewashing composition for use in automatic dishwashing machines
US20080090745A1 (en) * 2006-10-13 2008-04-17 Fox Bryan P Expression of Streptomyces subtilism inhibitor (SSI) proteins in Bacillus and Streptomyces sp.
EP2412792A1 (en) * 2010-07-29 2012-02-01 The Procter & Gamble Company Liquid detergent composition
JP2012180514A (ja) * 2011-02-10 2012-09-20 Sanyo Chem Ind Ltd 液体洗剤組成物
JP5953312B2 (ja) * 2011-10-12 2016-07-20 三洋化成工業株式会社 タンパク質性プロテアーゼインヒビター並びにこれを含有するタンパク質溶液及び洗剤組成物
JP6214382B2 (ja) * 2013-12-19 2017-10-18 花王株式会社 衣料用洗浄剤組成物
DE102022205593A1 (de) * 2022-06-01 2023-12-07 Henkel Ag & Co. Kgaa Wasch- und reinigungsmittel mit verbesserter enzymstabilität

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3324534A1 (de) 1983-07-07 1985-01-17 Ciba-Geigy Ag, Basel Modifizierte protease-inhibitoren, verfahren zu ihrer herstellung und daraus bereitete pharmazeutische mittel
US4801537A (en) 1984-06-08 1989-01-31 Genex Corporation Vector for expression of polypeptides in bacilli
US4760130A (en) * 1984-12-06 1988-07-26 Synergen Biologicals, Inc. Serine protease inhibitors and methods for isolation of same
DE3785102T2 (de) 1986-01-03 1993-07-22 Genetics Inst Verfahren zur herstellung von faktor-viii:c-typ-proteinen.
US5180667A (en) 1988-03-07 1993-01-19 Ciba-Geigy Corporation Genes encoding eglin C mutants
ES2063161T3 (es) 1988-03-07 1995-01-01 Ciba Geigy Ag Proteinas modificadas.
US5039446A (en) 1988-07-01 1991-08-13 Genencor International, Inc. Liquid detergent with stabilized enzyme
JPH0648988B2 (ja) 1988-07-26 1994-06-29 工業技術院長 トロンビン阻害物質の製造法
WO1990002175A1 (en) 1988-08-16 1990-03-08 Novo Nordisk A/S A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors
US5550042A (en) 1989-03-06 1996-08-27 The Board Of Regents Of The University Of Texas System Serine protease mutants of the chymotrypsin superfamily resistant to inhibition by their cognate inhibitors and genes encoding the same and serine protease inhibitor mutants and genes encoding the same
JPH0399099A (ja) * 1989-09-12 1991-04-24 Tsumura & Co ポリペプチドおよび該ポリペプチドを有効成分とするプロテアーゼ阻害剤
DK204290D0 (da) 1990-08-24 1990-08-24 Novo Nordisk As Enzymatisk detergentkomposition og fremgangsmaade til enzymstabilisering
US5674833A (en) 1990-09-18 1997-10-07 Novo Nordisk A/S Detergent compositions containing protease and novel inhibitors for use therein
DK223790D0 (da) 1990-09-18 1990-09-18 Novo Nordisk As Proteaseholdig detergentkomposition
US5178789A (en) 1991-06-27 1993-01-12 Genencor International, Inc. Liquid detergent with stabilized enzyme
US5527487A (en) 1991-11-27 1996-06-18 Novo Nordisk A/S Enzymatic detergent composition and method for enzyme stabilization
US5371198A (en) 1991-12-16 1994-12-06 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DK23692D0 (da) 1992-02-25 1992-02-25 Novo Nordisk As Detergentkomposition
US5623059A (en) 1992-03-09 1997-04-22 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DK43192D0 (da) 1992-03-31 1992-03-31 Novo Nordisk As Detergentkomposition
WO1995002055A1 (en) * 1993-07-09 1995-01-19 Michael Laskowski Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain
US5616485A (en) 1993-12-23 1997-04-01 Cangene Corporation Streptomyces proteases and improved streptomyces strains for expression of peptides and polypeptides
JPH0838191A (ja) 1994-05-27 1996-02-13 Japan Energy Corp プロテア−ゼインヒビタ−ｓｓｉと異種蛋白質との融合蛋白質の製造方法
WO1997015670A1 (en) 1995-10-25 1997-05-01 Arris Pharmaceutical Corporation Novel subtilisin inhibitors

Also Published As

Publication number Publication date
EP0929577B1 (en) 2003-06-04
ATE242270T1 (de) 2003-06-15
WO1998013387A1 (en) 1998-04-02
EP0929577A1 (en) 1999-07-21
US6579698B1 (en) 2003-06-17
DE69722639D1 (de) 2003-07-10
BR9711540A (pt) 2001-06-19
JP2000506394A (ja) 2000-05-30
AR009819A1 (es) 2000-05-03
CA2266323A1 (en) 1998-04-02
DE69722639T2 (de) 2004-04-29

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