DK0874640T3 - Cyclosporinformulering - Google Patents

Cyclosporinformulering

Info

Publication number
DK0874640T3
DK0874640T3 DK97901147T DK97901147T DK0874640T3 DK 0874640 T3 DK0874640 T3 DK 0874640T3 DK 97901147 T DK97901147 T DK 97901147T DK 97901147 T DK97901147 T DK 97901147T DK 0874640 T3 DK0874640 T3 DK 0874640T3
Authority
DK
Denmark
Prior art keywords
pct
weight
compositions
dimethyl
sec
Prior art date
Application number
DK97901147T
Other languages
Danish (da)
English (en)
Inventor
Milan Stuchlik
Tomas Andrysek
Alexander Jegorov
Ales Husek
Vladimir Matha
Josef Stuchlik
Original Assignee
Ivax Pharmaceuticals Sro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Pharmaceuticals Sro filed Critical Ivax Pharmaceuticals Sro
Application granted granted Critical
Publication of DK0874640T3 publication Critical patent/DK0874640T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97901147T 1996-01-18 1997-01-17 Cyclosporinformulering DK0874640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ1996169A CZ288631B6 (cs) 1996-01-18 1996-01-18 Léčivé přípravky s obsahem cyklosporinu
PCT/GB1997/000131 WO1997026003A1 (en) 1996-01-18 1997-01-17 Cyclosporin formulation

Publications (1)

Publication Number Publication Date
DK0874640T3 true DK0874640T3 (da) 2003-11-17

Family

ID=5461334

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97901147T DK0874640T3 (da) 1996-01-18 1997-01-17 Cyclosporinformulering

Country Status (12)

Country Link
US (1) US6046163A (ko)
EP (1) EP0874640B1 (ko)
JP (1) JP4005134B2 (ko)
KR (1) KR100471680B1 (ko)
AT (1) ATE245436T1 (ko)
AU (1) AU1449497A (ko)
CZ (1) CZ288631B6 (ko)
DE (1) DE69723671T2 (ko)
DK (1) DK0874640T3 (ko)
ES (1) ES2207714T3 (ko)
PT (1) PT874640E (ko)
WO (1) WO1997026003A1 (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
CZ288739B6 (cs) * 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
US6465016B2 (en) * 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
CZ267796A3 (cs) 1996-09-12 1998-04-15 Galena A.S. Léčivé přípravky, zejména pro vnitřní aplikaci, ve formě samomikroemulgujících terapeutických systémů
JP4761093B2 (ja) 1997-12-10 2011-08-31 シクロスポリン セラポイティクス リミテッド オメガ−３脂肪酸油を含む医薬組成物
US6136985A (en) * 1997-12-23 2000-10-24 Dcv, Inc. CLA esters and uses thereof
US6395810B1 (en) 1998-03-04 2002-05-28 Ato B.V. Bicyclooctane derivatives as plasticizers
CA2333648C (en) 1998-05-29 2008-10-21 Rtp Pharma Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
DE60020382T2 (de) * 1999-09-21 2006-01-26 Skyepharma Canada Inc., Verdun Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AUPQ877300A0 (en) * 2000-07-13 2000-08-03 Johnson & Johnson Pacific Pty Limited Topical treatment of skin
ATE437629T1 (de) * 2001-10-19 2009-08-15 Isotechnika Inc Neue cyclosporin-analoge mikroemulsionsvorkonzentrate
WO2003103582A2 (en) * 2002-06-05 2003-12-18 Ivax Corporation Reduction of gelatin cross-linking
EP1437129B2 (de) * 2003-01-08 2012-05-09 Swiss Caps Rechte und Lizenzen AG Formkörper bestehend aus gelatinfreiem Material und gefüllt mit einer flüssigen Füllmasse
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) * 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
FR2971941B1 (fr) * 2011-02-24 2013-08-02 Physica Pharma Compositions pharmaceutiques administrables par voie cutanee et destinees au traitement local de la dermatite atopique canine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
AU609242B2 (en) * 1988-01-29 1991-04-26 Novartis Ag Cyclosporin compositions
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
ES2052289T3 (es) * 1990-02-23 1994-07-01 Basf Ag Empleo de mezclas a partir de esteres de acidos grasos de poliglicerina como emulsionantes en preparaciones cosmeticas y farmaceuticas.
CZ278863B6 (en) * 1992-09-07 1994-07-13 Galena Medicinal preparations with n-methylated cyclic undecapeptides
CN1077800C (zh) * 1993-07-01 2002-01-16 韩美药品工业株式会社 环孢菌素软胶囊组合物
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
EP0690697A1 (en) * 1993-12-24 1996-01-10 Koninklijke Philips Electronics N.V. Grase mri with read gradient polarity correction and t 2? measurement
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
KR0167613B1 (ko) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물

Also Published As

Publication number Publication date
ES2207714T3 (es) 2004-06-01
ATE245436T1 (de) 2003-08-15
DE69723671T2 (de) 2004-04-22
JP4005134B2 (ja) 2007-11-07
KR100471680B1 (ko) 2007-04-25
CZ288631B6 (cs) 2001-08-15
WO1997026003A1 (en) 1997-07-24
US6046163A (en) 2000-04-04
AU1449497A (en) 1997-08-11
CZ16996A3 (en) 1997-08-13
DE69723671D1 (de) 2003-08-28
EP0874640A1 (en) 1998-11-04
KR19990077360A (ko) 1999-10-25
EP0874640B1 (en) 2003-07-23
PT874640E (pt) 2003-12-31
JP2000503314A (ja) 2000-03-21

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