DK0872554T3 - Forbedret carotenoidproduktion ved fermentering - Google Patents

Forbedret carotenoidproduktion ved fermentering

Info

Publication number
DK0872554T3
DK0872554T3 DK97120324T DK97120324T DK0872554T3 DK 0872554 T3 DK0872554 T3 DK 0872554T3 DK 97120324 T DK97120324 T DK 97120324T DK 97120324 T DK97120324 T DK 97120324T DK 0872554 T3 DK0872554 T3 DK 0872554T3
Authority
DK
Denmark
Prior art keywords
fermentation
carotenoid production
adonixanthin
astaxanthin
directed
Prior art date
Application number
DK97120324T
Other languages
English (en)
Inventor
Luis Pasamontes
Yuri Tsygankov
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0872554T3 publication Critical patent/DK0872554T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
DK97120324T 1996-12-02 1997-11-20 Forbedret carotenoidproduktion ved fermentering DK0872554T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96810839 1996-12-02

Publications (1)

Publication Number Publication Date
DK0872554T3 true DK0872554T3 (da) 2003-08-25

Family

ID=8225762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97120324T DK0872554T3 (da) 1996-12-02 1997-11-20 Forbedret carotenoidproduktion ved fermentering

Country Status (11)

Country Link
US (3) US6291204B1 (da)
EP (1) EP0872554B1 (da)
JP (1) JPH10155497A (da)
CN (1) CN1325648C (da)
AT (1) ATE242812T1 (da)
BR (1) BR9705676A (da)
DE (1) DE69722766T2 (da)
DK (1) DK0872554T3 (da)
ES (1) ES2200110T3 (da)
ID (1) ID17683A (da)
IN (1) IN190903B (da)

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DE19909637A1 (de) * 1999-03-05 2000-09-07 Peter Beyer Verfahren zur Verbesserung des agronomischen Wertes und der ernährungsphysiologischen Eigenschaften von Pflanzen
FR2792335A1 (fr) * 1999-04-19 2000-10-20 Thallia Pharmaceuticals Cyanobacteries sur-exprimant un gene implique dans la voie de biosynthese des carotenoides
US20050005310A1 (en) * 1999-07-12 2005-01-06 Genentech, Inc. Expression vectors and methods
WO2001007567A1 (en) * 1999-07-27 2001-02-01 Food Industry Research And Development Institute Engineering of metabolic control
US6818424B2 (en) * 2000-09-01 2004-11-16 E. I. Du Pont De Nemours And Company Production of cyclic terpenoids
US6660507B2 (en) 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
ATE405638T1 (de) 2001-06-06 2008-09-15 Dsm Ip Assets Bv Verbesserte isoprenoid herstellung
JP2003304875A (ja) * 2002-04-15 2003-10-28 Nippon Oil Corp カンタキサンチンの製造方法
EP1543144B1 (en) * 2002-09-27 2007-05-02 DSM IP Assets B.V. Production of zeaxanthin and beta-cryptoxanthin by phaffia
JP2006500046A (ja) * 2002-09-27 2006-01-05 ディーエスエム アイピー アセッツ ビー．ブイ． ファフィアによるカンタキサンチンの製造方法
US7091031B2 (en) * 2004-08-16 2006-08-15 E. I. Du Pont De Nemours And Company Carotenoid hydroxylase enzymes
US7074604B1 (en) 2004-12-29 2006-07-11 E. I. Du Pont De Nemours And Company Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes
GB0501365D0 (en) * 2005-01-21 2005-03-02 Promar As Compositions
BRPI0609040B1 (pt) 2005-03-18 2018-07-31 Microbia, Inc. Fungo recombinante do gênero yarrowia, método de produção de um carotenóide e método de preparo de um aditivo alimentício ou ração contendo um carotenóide
CN100387726C (zh) * 2005-03-28 2008-05-14 浙江省农业科学院 一种β-胡萝卜素的生产方法
JP2006280297A (ja) * 2005-04-01 2006-10-19 Tosoh Corp ゲラニルゲラニル２リン酸合成酵素及びその遺伝子等
DE102005049072A1 (de) * 2005-10-13 2007-04-19 Peter und Traudl Engelhorn-Stiftung zur Förderung der Biotechnologie und Gentechnik Astaxanthinbiosynthese in Eukaryoten
JP5023474B2 (ja) * 2005-10-28 2012-09-12 東ソー株式会社 カロテノイド合成微生物の作製方法およびカロテノイドの製造方法
WO2007049416A1 (ja) * 2005-10-28 2007-05-03 Tosoh Corporation カロテノイド合成微生物の作製方法およびカロテノイドの製造方法
US7393671B2 (en) * 2006-03-30 2008-07-01 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolases
US7422873B2 (en) * 2006-03-31 2008-09-09 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolase
EP2078092A2 (en) 2006-09-28 2009-07-15 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US7629823B2 (en) * 2006-10-04 2009-12-08 Power Integrations, Inc. Method and apparatus for pulse width modulation
KR100832584B1 (ko) * 2007-04-05 2008-05-27 에스케이에너지 주식회사 라이코펜의 생합성에 관여하는 유전자, 그 유전자를포함하는 재조합 벡터, 및 그 재조합 벡터로 형질전환된미생물
KR101441613B1 (ko) 2007-05-04 2014-09-26 아미코젠주식회사 재조합 대장균을 이용한 라이코펜 생산 방법
JP4969370B2 (ja) * 2007-08-29 2012-07-04 Ｊｘ日鉱日石エネルギー株式会社 カロテノイドの製造方法
TW200934872A (en) 2008-02-05 2009-08-16 Echem Hightech Co Ltd A strain of genetically reengineered escherichia coli for biosynthesis of high yield carotenoids after mutation screening
US8313659B2 (en) * 2009-07-10 2012-11-20 Seagate Technology Llc Fabrication of multi-dimensional microstructures
IN2014CN01129A (da) * 2011-08-08 2015-04-10 Evolva Sa
CN106801028B (zh) * 2017-01-17 2019-12-31 中山大学 产高含量玉米黄素或虾青素工程菌及其应用
WO2018222946A1 (en) 2017-06-01 2018-12-06 Knipbio, Inc. Heterologous carotenoid production in microorganisms
CN108148763A (zh) * 2018-03-08 2018-06-12 青岛旭能生物工程有限责任公司 一种通过流加方法提高摇瓶发酵纤细裸藻产量的方法
CN109609519A (zh) * 2018-10-31 2019-04-12 昆明理工大学 一种基因RKcrtYB及其应用
CN109536518A (zh) * 2018-10-31 2019-03-29 昆明理工大学 一种八氢番茄红素脱氢酶基因RKcrtI及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69018117T2 (de) 1989-04-21 1995-10-26 Kirin Brewery Zur Synthese von Karotinoiden verwendbare DNA-Sequenzen.
JP3782442B2 (ja) * 1990-03-02 2006-06-07 ビーピー・コーポレーション・ノース・アメリカ・インコーポレーテッド 遺伝子操作した宿主におけるカロテノイドの生合成
US5607839A (en) 1993-07-22 1997-03-04 Nippon Oil Company, Ltd. Bacteria belonging to new genus process for production of carotenoids using same
AU702584B2 (en) * 1993-12-27 1999-02-25 Kirin Holdings Kabushiki Kaisha DNA strands useful for the synthesis of xanthophylls and the process for producing the xanthophylls
DK0747483T3 (da) * 1995-06-09 2004-06-28 Dsm Ip Assets Bv Fermentativ carotenoid-produktion

Also Published As

Publication number Publication date
EP0872554A3 (en) 2000-06-07
EP0872554A2 (en) 1998-10-21
US7063956B2 (en) 2006-06-20
US20040058410A1 (en) 2004-03-25
CN1325648C (zh) 2007-07-11
US6291204B1 (en) 2001-09-18
IN190903B (da) 2003-08-30
US6677134B2 (en) 2004-01-13
CN1184159A (zh) 1998-06-10
DE69722766T2 (de) 2004-04-22
DE69722766D1 (de) 2003-07-17
ATE242812T1 (de) 2003-06-15
ID17683A (id) 1998-01-22
EP0872554B1 (en) 2003-06-11
JPH10155497A (ja) 1998-06-16
US20030022273A1 (en) 2003-01-30
ES2200110T3 (es) 2004-03-01
BR9705676A (pt) 1999-05-25

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