DK0808367T3 - Vaskulære slimhindeaddressiner samt anvendelse deraf - Google Patents
Vaskulære slimhindeaddressiner samt anvendelse derafInfo
- Publication number
- DK0808367T3 DK0808367T3 DK96906504T DK96906504T DK0808367T3 DK 0808367 T3 DK0808367 T3 DK 0808367T3 DK 96906504 T DK96906504 T DK 96906504T DK 96906504 T DK96906504 T DK 96906504T DK 0808367 T3 DK0808367 T3 DK 0808367T3
- Authority
- DK
- Denmark
- Prior art keywords
- madcam
- primate
- recombinant
- proteins
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/386,857 US6551593B1 (en) | 1995-02-10 | 1995-02-10 | Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam |
US08/523,004 US7750137B2 (en) | 1995-09-01 | 1995-09-01 | Mucosal vascular addressins |
PCT/US1996/002153 WO1996024673A1 (en) | 1995-02-10 | 1996-02-12 | Mucosal vascular addressins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0808367T3 true DK0808367T3 (da) | 2007-11-05 |
Family
ID=27011628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96906504T DK0808367T3 (da) | 1995-02-10 | 1996-02-12 | Vaskulære slimhindeaddressiner samt anvendelse deraf |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0808367B1 (de) |
JP (1) | JP4205162B2 (de) |
AT (1) | ATE366809T1 (de) |
AU (1) | AU4986296A (de) |
CA (1) | CA2212702C (de) |
DE (1) | DE69637155T2 (de) |
DK (1) | DK0808367T3 (de) |
ES (1) | ES2290955T3 (de) |
MX (1) | MX9706049A (de) |
NZ (1) | NZ303523A (de) |
PT (1) | PT808367E (de) |
WO (1) | WO1996024673A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0948597A4 (de) * | 1996-11-01 | 2002-07-10 | Human Genome Sciences Inc | Menschliches, Schleimhaut-spezifisches Addressin-Zelladhäsionsmolekül (MAdCAM-1) und dessen Spleissvarianten |
WO1998051345A2 (en) * | 1997-05-09 | 1998-11-19 | The John P. Robarts Research Institute | Method for dislodging infiltrated leukocytes from a tissue |
AU2007201698B2 (en) * | 1998-05-13 | 2011-10-13 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
US7090845B2 (en) | 1998-05-13 | 2006-08-15 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
ATE424417T1 (de) * | 1998-05-13 | 2009-03-15 | Genentech Inc | Diagnose und behandlung von hepatischen krankheiten |
AUPR524101A0 (en) * | 2001-05-25 | 2001-06-21 | Council Of The Queensland Institute Of Medical Research, The | Antigen targeting |
WO2003047526A2 (en) * | 2001-11-30 | 2003-06-12 | Incyte Genomics, Inc. | Cell adhesion and extracellular matrix proteins |
US20070202097A1 (en) * | 2003-03-10 | 2007-08-30 | Krissansen Geoffrey W | Monoclonal Antibodies That Recognise Mucosal Addressin Cell Adhesion Molecule-1 (Madcam-1), Soluble Madcam-1 And Uses Thereof |
CN1812804B (zh) | 2003-05-01 | 2013-06-12 | 斯克里普斯研究学院 | 选择性r-钙黏着蛋白拮抗剂和方法 |
ATE522547T1 (de) * | 2004-01-09 | 2011-09-15 | Pfizer | Antikörper zu madcam |
LT3530673T (lt) * | 2004-09-03 | 2022-06-10 | Genentech, Inc. | Humanizuoti anti-beta7 antagonistai ir jų panaudojimas |
JP2009500390A (ja) * | 2005-07-08 | 2009-01-08 | ファイザー・リミテッド | 新規MAdCAM抗体 |
WO2007007152A2 (en) * | 2005-07-11 | 2007-01-18 | Pfizer Limited | Anti-madcam antibodies to treat metastatic cancers and chloroma |
MX2010012368A (es) * | 2008-05-16 | 2010-12-06 | Genentech Inc | Uso de biomarcadores para evaluar un tratamiento contra trastornos inflamatorios gastrointestinales con antagonistas de beta7-integrina. |
DK2704742T3 (en) | 2011-05-02 | 2017-10-23 | Millennium Pharm Inc | FORMULATION FOR ANTI-4-7 ANTIBODY |
UA116189C2 (uk) | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
JP2017537105A (ja) | 2014-11-26 | 2017-12-14 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | 瘻孔を伴うクローン病の治療用ベドリズマブ |
US20170360926A1 (en) | 2014-12-24 | 2017-12-21 | Millennium Pharmaceuticals, Inc. | PREDICTING OUTCOME OF TREATMENT WITH AN ANTI-alpha4beta7 INTEGRIN ANTIBODY |
MA41636A (fr) | 2015-03-06 | 2018-01-09 | Millennium Pharm Inc | Méthode de traitement de la cholangite sclérosante primitive |
IL261750B1 (en) | 2016-03-14 | 2024-03-01 | Millennium Pharm Inc | A method for preventing graft-versus-host disease |
MX2018011025A (es) | 2016-03-14 | 2019-01-10 | Millennium Pharm Inc | Metodos para tratar o prevenir la enfermedad del injerto contra huésped. |
JP7069032B2 (ja) | 2016-03-24 | 2022-05-17 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | がん免疫治療における胃腸の免疫関連有害事象の治療方法 |
WO2017165742A1 (en) | 2016-03-24 | 2017-09-28 | Millennium Pharmaceuticals, Inc. | Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments |
MA44864A (fr) | 2016-05-04 | 2019-03-13 | Icahn School Med Mount Sinai | Trithérapie pour le traitement d'une maladie intestinale inflammatoire |
US11389533B2 (en) | 2016-06-12 | 2022-07-19 | Takeda Pharmaceutical Company Limited | Method of treating inflammatory bowel disease |
WO2018104893A1 (en) | 2016-12-06 | 2018-06-14 | Glaxosmithkline Intellectual Property Development Limited | Alpha4-beta7 antibodies with incrased fcrn binding and/or half-life |
WO2018200818A2 (en) | 2017-04-28 | 2018-11-01 | Millennium Pharmaceuticals, Inc. | Method of treating pediatric disorders |
US20190169291A1 (en) | 2017-07-14 | 2019-06-06 | Pfizer Inc. | Antibodies to MAdCAM |
AU2020279240A1 (en) * | 2019-05-20 | 2021-12-23 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5675794A (en) * | 1992-12-15 | 1994-07-04 | Board Of Trustees Of The Leland Stanford Junior University | Mucosal vascular addressin, dna and expression |
-
1996
- 1996-02-12 PT PT96906504T patent/PT808367E/pt unknown
- 1996-02-12 DE DE69637155T patent/DE69637155T2/de not_active Expired - Lifetime
- 1996-02-12 ES ES96906504T patent/ES2290955T3/es not_active Expired - Lifetime
- 1996-02-12 AT AT96906504T patent/ATE366809T1/de active
- 1996-02-12 WO PCT/US1996/002153 patent/WO1996024673A1/en active IP Right Grant
- 1996-02-12 MX MX9706049A patent/MX9706049A/es active IP Right Grant
- 1996-02-12 NZ NZ303523A patent/NZ303523A/en not_active IP Right Cessation
- 1996-02-12 AU AU49862/96A patent/AU4986296A/en not_active Abandoned
- 1996-02-12 DK DK96906504T patent/DK0808367T3/da active
- 1996-02-12 JP JP52449196A patent/JP4205162B2/ja not_active Expired - Fee Related
- 1996-02-12 CA CA2212702A patent/CA2212702C/en not_active Expired - Lifetime
- 1996-02-12 EP EP96906504A patent/EP0808367B1/de not_active Revoked
Also Published As
Publication number | Publication date |
---|---|
DE69637155D1 (de) | 2007-08-23 |
JPH10513365A (ja) | 1998-12-22 |
NZ303523A (en) | 2002-02-01 |
JP4205162B2 (ja) | 2009-01-07 |
CA2212702C (en) | 2010-04-20 |
AU4986296A (en) | 1996-08-27 |
MX9706049A (es) | 1998-02-28 |
EP0808367B1 (de) | 2007-07-11 |
DE69637155T2 (de) | 2008-02-07 |
CA2212702A1 (en) | 1996-08-15 |
EP0808367A1 (de) | 1997-11-26 |
WO1996024673A1 (en) | 1996-08-15 |
ES2290955T3 (es) | 2008-02-16 |
PT808367E (pt) | 2007-10-22 |
ATE366809T1 (de) | 2007-08-15 |
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