DK0808367T3 - Vaskulære slimhindeaddressiner samt anvendelse deraf - Google Patents
Vaskulære slimhindeaddressiner samt anvendelse derafInfo
- Publication number
- DK0808367T3 DK0808367T3 DK96906504T DK96906504T DK0808367T3 DK 0808367 T3 DK0808367 T3 DK 0808367T3 DK 96906504 T DK96906504 T DK 96906504T DK 96906504 T DK96906504 T DK 96906504T DK 0808367 T3 DK0808367 T3 DK 0808367T3
- Authority
- DK
- Denmark
- Prior art keywords
- madcam
- primate
- recombinant
- proteins
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/386,857 US6551593B1 (en) | 1995-02-10 | 1995-02-10 | Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam |
US08/523,004 US7750137B2 (en) | 1995-09-01 | 1995-09-01 | Mucosal vascular addressins |
PCT/US1996/002153 WO1996024673A1 (en) | 1995-02-10 | 1996-02-12 | Mucosal vascular addressins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0808367T3 true DK0808367T3 (da) | 2007-11-05 |
Family
ID=27011628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96906504T DK0808367T3 (da) | 1995-02-10 | 1996-02-12 | Vaskulære slimhindeaddressiner samt anvendelse deraf |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0808367B1 (da) |
JP (1) | JP4205162B2 (da) |
AT (1) | ATE366809T1 (da) |
AU (1) | AU4986296A (da) |
CA (1) | CA2212702C (da) |
DE (1) | DE69637155T2 (da) |
DK (1) | DK0808367T3 (da) |
ES (1) | ES2290955T3 (da) |
MX (1) | MX9706049A (da) |
NZ (1) | NZ303523A (da) |
PT (1) | PT808367E (da) |
WO (1) | WO1996024673A1 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0948597A4 (en) * | 1996-11-01 | 2002-07-10 | Human Genome Sciences Inc | Human, mucous membrane-specific addressin cell adhesion molecule (MAdCAM-1) and its splice variants |
AU7348798A (en) * | 1997-05-09 | 1998-12-08 | John P. Robarts Research Institute, The | Method for dislodging infiltrated leukocytes from a tissue |
AU2007201698B2 (en) * | 1998-05-13 | 2011-10-13 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
US7090845B2 (en) | 1998-05-13 | 2006-08-15 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
CA2330000C (en) * | 1998-05-13 | 2015-06-23 | Genentech, Inc. | Diagnosis and treatment of hepatic disorders |
AUPR524101A0 (en) | 2001-05-25 | 2001-06-21 | Council Of The Queensland Institute Of Medical Research, The | Antigen targeting |
WO2003047526A2 (en) * | 2001-11-30 | 2003-06-12 | Incyte Genomics, Inc. | Cell adhesion and extracellular matrix proteins |
WO2004081049A1 (en) * | 2003-03-10 | 2004-09-23 | Auckland Uniservices Limited | Monoclonal antibodies that recognise mucosal addressin cell adhesion molecule-1 (madcam-1), soluble madcam-1 and uses thereof |
JP4613300B2 (ja) | 2003-05-01 | 2011-01-12 | ザ スクリプス リサーチ インスティチュート | 選択的r−カドヘリンアンタゴニストおよび方法 |
JP4315982B2 (ja) | 2004-01-09 | 2009-08-19 | ファイザー インコーポレイティッド | MAdCAMに対する抗体 |
RU2453558C2 (ru) | 2004-09-03 | 2012-06-20 | Дженентек, Инк. | Гуманизированные антагонистические антитела против бета7 и их применение |
EP1904531B1 (en) * | 2005-07-08 | 2010-10-06 | Pfizer Limited | Madcam antibodies |
WO2007007152A2 (en) * | 2005-07-11 | 2007-01-18 | Pfizer Limited | Anti-madcam antibodies to treat metastatic cancers and chloroma |
EP2279004B1 (en) * | 2008-05-16 | 2015-01-14 | F. Hoffmann-La Roche AG | Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7integrin antagonists |
UA116189C2 (uk) | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
CN108969469A (zh) | 2011-05-02 | 2018-12-11 | 米伦纽姆医药公司 | 抗α4β7抗体的制剂 |
JP2017537105A (ja) | 2014-11-26 | 2017-12-14 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | 瘻孔を伴うクローン病の治療用ベドリズマブ |
JP6904905B2 (ja) | 2014-12-24 | 2021-07-21 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | 抗α4β7インテグリン抗体による治療の結果の予測 |
MA41636A (fr) | 2015-03-06 | 2018-01-09 | Millennium Pharm Inc | Méthode de traitement de la cholangite sclérosante primitive |
US20200002422A1 (en) | 2016-03-14 | 2020-01-02 | Millennium Pharmaceuticals, Inc. | Method of preventing graft versus host disease |
CN109153721A (zh) | 2016-03-14 | 2019-01-04 | 千禧制药公司 | 治疗或预防移植物抗宿主疾病的方法 |
TW201735949A (zh) | 2016-03-24 | 2017-10-16 | 千禧製藥公司 | 治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法 |
EP3433275A1 (en) | 2016-03-24 | 2019-01-30 | Millennium Pharmaceuticals, Inc. | Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments |
MA44864A (fr) | 2016-05-04 | 2019-03-13 | Icahn School Med Mount Sinai | Trithérapie pour le traitement d'une maladie intestinale inflammatoire |
MA45245A (fr) | 2016-06-12 | 2019-04-17 | Millennium Pharm Inc | Méthode de traitement de maladie intestinale inflammatoire |
WO2018104893A1 (en) | 2016-12-06 | 2018-06-14 | Glaxosmithkline Intellectual Property Development Limited | Alpha4-beta7 antibodies with incrased fcrn binding and/or half-life |
KR20190141148A (ko) | 2017-04-28 | 2019-12-23 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 소아 장애를 치료하는 방법 |
CR20200076A (es) * | 2017-07-14 | 2020-06-10 | Pfizer | ANTICUERPOS CONTRA MAdCAM |
US11739146B2 (en) * | 2019-05-20 | 2023-08-29 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994013312A1 (en) * | 1992-12-15 | 1994-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Mucosal vascular addressin, dna and expression |
-
1996
- 1996-02-12 CA CA2212702A patent/CA2212702C/en not_active Expired - Lifetime
- 1996-02-12 EP EP96906504A patent/EP0808367B1/en not_active Revoked
- 1996-02-12 JP JP52449196A patent/JP4205162B2/ja not_active Expired - Fee Related
- 1996-02-12 DE DE69637155T patent/DE69637155T2/de not_active Expired - Lifetime
- 1996-02-12 NZ NZ303523A patent/NZ303523A/en not_active IP Right Cessation
- 1996-02-12 PT PT96906504T patent/PT808367E/pt unknown
- 1996-02-12 AT AT96906504T patent/ATE366809T1/de active
- 1996-02-12 ES ES96906504T patent/ES2290955T3/es not_active Expired - Lifetime
- 1996-02-12 MX MX9706049A patent/MX9706049A/es active IP Right Grant
- 1996-02-12 WO PCT/US1996/002153 patent/WO1996024673A1/en active IP Right Grant
- 1996-02-12 AU AU49862/96A patent/AU4986296A/en not_active Abandoned
- 1996-02-12 DK DK96906504T patent/DK0808367T3/da active
Also Published As
Publication number | Publication date |
---|---|
AU4986296A (en) | 1996-08-27 |
ATE366809T1 (de) | 2007-08-15 |
ES2290955T3 (es) | 2008-02-16 |
PT808367E (pt) | 2007-10-22 |
CA2212702A1 (en) | 1996-08-15 |
EP0808367A1 (en) | 1997-11-26 |
DE69637155T2 (de) | 2008-02-07 |
CA2212702C (en) | 2010-04-20 |
DE69637155D1 (de) | 2007-08-23 |
WO1996024673A1 (en) | 1996-08-15 |
JPH10513365A (ja) | 1998-12-22 |
JP4205162B2 (ja) | 2009-01-07 |
MX9706049A (es) | 1998-02-28 |
EP0808367B1 (en) | 2007-07-11 |
NZ303523A (en) | 2002-02-01 |
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