DK0808162T3 - Anvendelse af carbazolforbindelser til behandling af kongestiv hjertesvigt - Google Patents

Anvendelse af carbazolforbindelser til behandling af kongestiv hjertesvigt

Info

Publication number
DK0808162T3
DK0808162T3 DK96902984T DK96902984T DK0808162T3 DK 0808162 T3 DK0808162 T3 DK 0808162T3 DK 96902984 T DK96902984 T DK 96902984T DK 96902984 T DK96902984 T DK 96902984T DK 0808162 T3 DK0808162 T3 DK 0808162T3
Authority
DK
Denmark
Prior art keywords
heart failure
congestive heart
carbazole compounds
treat congestive
carvedilol
Prior art date
Application number
DK96902984T
Other languages
Danish (da)
English (en)
Inventor
Gisbert Sponer
Klaus Strein
Mary Ann Lukas-Laskey
Robert Ruffolo Jr
Neil Shusterman
Original Assignee
Boehringer Mannheim Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26012210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0808162(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE1995103995 external-priority patent/DE19503995C2/de
Application filed by Boehringer Mannheim Pharm Corp filed Critical Boehringer Mannheim Pharm Corp
Application granted granted Critical
Publication of DK0808162T3 publication Critical patent/DK0808162T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK96902984T 1995-02-08 1996-02-07 Anvendelse af carbazolforbindelser til behandling af kongestiv hjertesvigt DK0808162T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1995103995 DE19503995C2 (de) 1995-02-08 1995-02-08 Verwendung von Carvedilol zur Verminderung der Mortalität bei Patienten mit eingeschränkter myocardialer Funktion
US08/483,635 US5760069A (en) 1995-02-08 1995-06-07 Method of treatment for decreasing mortality resulting from congestive heart failure
PCT/EP1996/000498 WO1996024348A2 (en) 1995-02-08 1996-02-07 Use of carbazole compounds for the treatment of congestive heart failure

Publications (1)

Publication Number Publication Date
DK0808162T3 true DK0808162T3 (da) 1999-11-15

Family

ID=26012210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96902984T DK0808162T3 (da) 1995-02-08 1996-02-07 Anvendelse af carbazolforbindelser til behandling af kongestiv hjertesvigt

Country Status (27)

Country Link
US (6) US5760069A (ja)
EP (1) EP0808162B1 (ja)
JP (1) JP3546058B2 (ja)
KR (1) KR100295940B1 (ja)
CN (1) CN1093760C (ja)
AT (1) ATE179891T1 (ja)
AU (1) AU702106C (ja)
BR (1) BR9607111A (ja)
CA (1) CA2212548C (ja)
CZ (1) CZ292002B6 (ja)
DE (1) DE69602424T2 (ja)
DK (1) DK0808162T3 (ja)
ES (1) ES2134588T3 (ja)
FI (1) FI973255A0 (ja)
GR (1) GR3030966T3 (ja)
HK (1) HK1014861A1 (ja)
HU (1) HUP9900773A3 (ja)
NO (1) NO314830B1 (ja)
NZ (1) NZ301692A (ja)
PL (1) PL321737A1 (ja)
RO (1) RO121629B1 (ja)
RU (1) RU2197242C2 (ja)
SI (1) SI0808162T1 (ja)
SK (1) SK106897A3 (ja)
UA (1) UA55382C2 (ja)
WO (1) WO1996024348A2 (ja)
ZA (1) ZA96994B (ja)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
PL332638A1 (en) * 1996-10-09 1999-09-27 Boehringer Mannheim Pharm Corp Method of inhibiting stress-activated proteinous kinases
ZA989365B (en) * 1997-10-15 1999-04-15 Boehringer Mannheim Pharm Corp Preparation for treating alzheimer's disease
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
TR200001362T2 (tr) * 1997-11-12 2000-09-21 Boehringer Mannheim Pharm Corp.-Smithkline Beckman Yeni karvedilol oral dozaj formu
US6664284B2 (en) 1998-07-23 2003-12-16 Roche Diagnostics Gmbh Stabilized carvedilol injection solution
DE19833119A1 (de) * 1998-07-23 2000-01-27 Roche Diagnostics Gmbh Spritzfertige Injektionslösungen enthaltend Carvedilol
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
US6465463B1 (en) * 1999-09-08 2002-10-15 Nitromed, Inc. Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
US7235237B2 (en) * 1999-10-29 2007-06-26 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US7537785B2 (en) * 1999-10-29 2009-05-26 Nitromed, Inc. Composition for treating vascular diseases characterized by nitric oxide insufficiency
US7708989B2 (en) * 1999-10-29 2010-05-04 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
AU780261B2 (en) * 1999-10-29 2005-03-10 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
WO2002000216A1 (en) * 2000-06-28 2002-01-03 Teva Pharmaceutical Industries Ltd. Carvedilol
EP1385509A4 (en) * 2001-04-02 2004-06-30 Smithkline Beecham Corp TREATMENT METHOD
WO2003028718A1 (en) * 2001-10-01 2003-04-10 Smithkline Beecham Corporation Novel formulations of carvedilol
WO2003028649A2 (en) * 2001-10-02 2003-04-10 Smithkline Beecham Corporation Novel composition of carvedilol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
SE0103749D0 (sv) * 2001-11-08 2001-11-08 Sahltech Ab Treatment of congestive heart failure
JP2005515226A (ja) * 2002-01-15 2005-05-26 テバ ファーマシューティカル インダストリーズ リミティド カルベジロールの結晶質固体及びそれらを調製するための方法
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
EP1499310A4 (en) * 2002-04-30 2005-12-07 Sb Pharmco Inc MONOCITRATE MONOHYDRATE OF CARVEDILOL
US6951880B2 (en) * 2002-05-16 2005-10-04 Genelabs Technologies, Inc. Aryl and heteroaryl compounds as antibacterial and antifungal agents
CN103254114A (zh) * 2002-06-27 2013-08-21 史密斯克莱.比奇曼（科克）有限公司 卡维地洛磷酸盐和/或其溶剂合物相应的组合物和/或治疗方法
JP2005533822A (ja) * 2002-06-27 2005-11-10 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド 臭化水素酸カルベジロール
PT1362590E (pt) * 2002-07-25 2004-05-31 Boehringer Ingelheim Pharma Utilizacao de cilobradina ou dos seus sais farmaceuticamente aceitaveis para o tratamento ou prevencao de falha cardiaca
US6632832B1 (en) 2002-09-10 2003-10-14 Dabur Research Foundation Anti-cancer activity of carvedilol and its isomers
US20050032879A1 (en) * 2003-08-07 2005-02-10 Temple Okarter Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases
JP2007512372A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および／または治療方法
US8734850B2 (en) * 2003-11-25 2014-05-27 Flamel Technologies Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
EP1778267A4 (en) * 2004-07-16 2010-01-06 Nitromed Inc COMPOSITIONS AND METHODS ASSOCIATED WITH HEART FAILURE
WO2006135757A1 (en) * 2005-06-09 2006-12-21 Teva Pharmaceutical Industries Ltd. Crystalline forms of carvedilol and processes for their preparation
EP1984010A4 (en) * 2006-02-17 2010-09-08 Nitromed Inc METHOD FOR USE OF HYDRALAZIN COMPOUNDS AND ISOSORBIDE DINITRATE OR ISOSORBIDE MONONITRATE
US8367112B2 (en) * 2006-02-28 2013-02-05 Alkermes Pharma Ireland Limited Nanoparticulate carverdilol formulations
US8703804B2 (en) * 2006-03-26 2014-04-22 Uti Limited Partnership Ryanodine receptor inhibitors and methods relating thereto
US20090306081A1 (en) * 2006-05-16 2009-12-10 Letts L Gordon Solid Dosage Formulations of Hydralazine Compounds and Nitric Oxide Donor Compounds
EP1991527A2 (en) * 2006-06-28 2008-11-19 Teva Pharmaceutical Industries Ltd Polymorphous forms of carvedilol phosphate
WO2008105794A1 (en) * 2007-02-26 2008-09-04 Teva Pharmaceutical Industries Ltd. Process for the purification of carvedilol or its salts thereof
US20090076116A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched carvediolo
AU2009246114B2 (en) 2008-05-16 2013-01-31 Corthera, Inc. Treating dyspnea associated with acute heart failure with relaxin
MX355697B (es) 2010-04-12 2018-04-27 Supernus Pharmaceuticals Inc Métodos para producir sales de viloxazina y polimorfos novedosos de las mismas.
KR20140057604A (ko) 2011-08-12 2014-05-13 베링거잉겔하임베트메디카게엠베하 고양잇과 동물의 심부전을 치료 및 예방하는 방법에 사용하기 위한 퍼니 전류 억제제
BR112018075984A2 (pt) * 2016-06-13 2019-04-02 Ascendia Pharmaceuticals, Llc composição de distribuição de fármaco parenteral para liberação sustentada
US10772869B1 (en) 2019-07-24 2020-09-15 ECI Pharmaceuticals, LLC Pharmaceutical compositions including carvedilol and methods of using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
SE460945B (sv) * 1987-01-15 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av furosemid
US5312828A (en) * 1989-06-14 1994-05-17 Finkelstein Joseph A Substituted imidazoles having angiotensin II receptor blocking activity
US5308862A (en) * 1993-03-05 1994-05-03 Boehringer Mannheim Pharmaceuticals Corporation - Smithkline Beecham Corp., Ltd. Partnership No. 1 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure

Also Published As

Publication number Publication date
AU702106B2 (en) 1999-02-11
US20010044455A1 (en) 2001-11-22
SK106897A3 (en) 1999-03-12
KR19980702085A (ko) 1998-07-15
NO314830B1 (no) 2003-06-02
ES2134588T3 (es) 1999-10-01
HK1014861A1 (en) 1999-10-08
MX9706042A (es) 1998-06-30
USRE40000E1 (en) 2008-01-08
JP3546058B2 (ja) 2004-07-21
NO973667L (no) 1997-08-08
FI973255A (fi) 1997-08-07
UA55382C2 (uk) 2003-04-15
BR9607111A (pt) 1997-11-04
CA2212548A1 (en) 1996-08-15
HUP9900773A2 (hu) 1999-07-28
CZ292002B6 (cs) 2003-07-16
CN1185106A (zh) 1998-06-17
WO1996024348A3 (en) 1996-10-03
AU702106C (en) 2005-02-17
US5902821A (en) 1999-05-11
PL321737A1 (en) 1997-12-22
US20030105138A1 (en) 2003-06-05
NO973667D0 (no) 1997-08-08
EP0808162A2 (en) 1997-11-26
KR100295940B1 (ko) 2001-08-07
RO121629B1 (ro) 2008-01-30
RU2197242C2 (ru) 2003-01-27
ZA96994B (en) 1997-10-27
HUP9900773A3 (en) 2000-04-28
US5760069A (en) 1998-06-02
WO1996024348A2 (en) 1996-08-15
JPH10513463A (ja) 1998-12-22
DE69602424T2 (de) 1999-10-07
GR3030966T3 (en) 1999-11-30
CZ246397A3 (cs) 1998-11-11
DE69602424D1 (de) 1999-06-17
CA2212548C (en) 1999-08-24
NZ301692A (en) 2000-09-29
ATE179891T1 (de) 1999-05-15
CN1093760C (zh) 2002-11-06
SI0808162T1 (en) 1999-10-31
AU4718196A (en) 1996-08-27
FI973255A0 (fi) 1997-08-07
EP0808162B1 (en) 1999-05-12
USRE40707E1 (en) 2009-05-05

Similar Documents

Publication Publication Date Title
DK0808162T3 (da) Anvendelse af carbazolforbindelser til behandling af kongestiv hjertesvigt
NO20013727L (no) Anvendelse av Botulinumtoksin B for fremstilling av et medikament
AU2001272666A1 (en) 2-adamantylethylamines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
IS4923A (is) Meðferðaráform við inngjöf á H+,K+-ATPasa-blokkara
ATE400258T1 (de) Transdermales buprenorphin-dosierschema zwecks schmerzstillung
MX9602442A (es) Un tratamiento con fluoroquinolona a dosis unica elevada.
DE69424777T2 (de) 3,4-diarylchromane zur behandlung von dermatitis
DE69227583D1 (de) Arylmorpholine, herstellung und verwendung
DE69218200D1 (de) Behandlung von leberkrebs
NZ299006A (en) Use of 4-dichlorophenyl tetrahydro N-methyl-1-naphthalenamine (sertraline) for heart attack treatment
EP1292292A4 (en) METHOD FOR THE TREATMENT OF HEART FAILURE
DK0703781T3 (da) Anvendelse af Efaroxan og derivater deraf til fremstilling af et lægemiddel til behandling af Parkinsons sygdom
DE69528068T2 (de) Conagenine zur prävention und behandlung von diarrhöe
ATE207353T1 (de) Verwendung von benzydamin zur behandlung von krankheitszuständen, die durch tnf verursacht werden
PT1305020E (pt) Utilizacao de fibratos para a preparacao de um medicamento util no tratamento da insuficiencia cardiaca congestiva
FR2416890A1 (fr) Derives de 1,5-benzothiazepines, leur preparation et leurs utilisations therapeutiques
ATE74505T1 (de) Schmerzpraeparat.
UA36762A (uk) Спосіб лікування хворих на обмежену склеродермію
OA09519A (fr) D-acide aspartique b-hydroxamate en tant que medicament
UA22022A (uk) Спосіб лікуваhhя хворих з високим ризиком розвитку поліоргаhhої hедостатhості
HUP9802142A2 (hu) Na+/H+ -ioncsere inhibítorok alkalmazása a központi idegrendszer betegségeinek kezelésére és megelőzésére alkalmas gyógyszerkészítmények előállítására
ATE243695T1 (de) 5-bicycloindolverbindungen
RU98105539A (ru) Способ лечения псориаза
NZ336321A (en) Use of benzothiophene (raloxifene) for treating breast cancer
RU92001939A (ru) Способ лечения псориаза