DK0804246T3 - Mitomycinholdige lægemiddelleveringssystemer - Google Patents

Mitomycinholdige lægemiddelleveringssystemer

Info

Publication number
DK0804246T3
DK0804246T3 DK94923825T DK94923825T DK0804246T3 DK 0804246 T3 DK0804246 T3 DK 0804246T3 DK 94923825 T DK94923825 T DK 94923825T DK 94923825 T DK94923825 T DK 94923825T DK 0804246 T3 DK0804246 T3 DK 0804246T3
Authority
DK
Denmark
Prior art keywords
mmc
pct
groups
carrier polymer
spacer
Prior art date
Application number
DK94923825T
Other languages
English (en)
Inventor
Etienne Honore Schacht
Paolo Ferruti
Ruth Duncan
Original Assignee
Europ Economic Community
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europ Economic Community filed Critical Europ Economic Community
Application granted granted Critical
Publication of DK0804246T3 publication Critical patent/DK0804246T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
DK94923825T 1993-08-18 1994-08-17 Mitomycinholdige lægemiddelleveringssystemer DK0804246T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9317213A GB2282384B8 (en) 1993-08-18 1993-08-18 Drug delivery agents incorporating mitomycin
PCT/IB1994/000259 WO1995005200A1 (en) 1993-08-18 1994-08-17 Drug delivery agents incorporating mitomycin

Publications (1)

Publication Number Publication Date
DK0804246T3 true DK0804246T3 (da) 2000-11-13

Family

ID=10740702

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94923825T DK0804246T3 (da) 1993-08-18 1994-08-17 Mitomycinholdige lægemiddelleveringssystemer

Country Status (12)

Country Link
US (1) US5738864A (da)
EP (1) EP0804246B1 (da)
JP (1) JPH09501674A (da)
AT (1) ATE192933T1 (da)
CA (1) CA2168007C (da)
DE (1) DE69424577T2 (da)
DK (1) DK0804246T3 (da)
ES (1) ES2145832T3 (da)
GB (1) GB2282384B8 (da)
GR (1) GR3034174T3 (da)
PT (1) PT804246E (da)
WO (1) WO1995005200A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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US5850855A (en) * 1990-01-09 1998-12-22 Ems-Inventa Ag Flexible coolant conduit and method of making same
AU6667198A (en) * 1997-02-26 1998-09-18 Eli Lilly And Company Process for preparing pharmaceutical compounds
US6251866B1 (en) 1997-08-05 2001-06-26 Watson Laboratories, Inc. Conjugates targeted to the interleukin-2 receptor
AU765409B2 (en) * 1998-10-30 2003-09-18 Daiichi Pharmaceutical Co., Ltd. DDS compounds and method for assaying the same
ES2294026T3 (es) * 2000-09-06 2008-04-01 Ap Pharma, Inc. Polimeros degradables de poliacetal.
US20030124742A1 (en) * 2001-08-22 2003-07-03 Prakash Ramesh K. Conjugates targeted to target receptors
ATE461681T1 (de) * 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
US8614228B2 (en) 2004-08-11 2013-12-24 Arqule, Inc. Quinone prodrug compositions and methods of use
WO2006020719A2 (en) 2004-08-11 2006-02-23 Arqule, Inc. Aminoacid conjugates of beta - lapachone for tumor targeting
JP5237821B2 (ja) 2005-12-05 2013-07-17 日東電工株式会社 ポリグルタミン酸−アミノ酸結合体および方法
US20080181852A1 (en) * 2007-01-29 2008-07-31 Nitto Denko Corporation Multi-functional Drug Carriers
JP5286822B2 (ja) * 2007-02-22 2013-09-11 Ｊｓｒ株式会社 ポリアミノ酸またはポリアミノ酸系共重合体の製造方法
CN104800856A (zh) * 2007-04-10 2015-07-29 日东电工株式会社 多功能聚谷氨酸盐药物载体
CN101687835B (zh) 2007-04-30 2015-08-19 艾科尔公司 苯醌化合物的羟基磺酸盐和它们的应用
WO2008141111A2 (en) * 2007-05-09 2008-11-20 Nitto Denko Corporation Polymers conjugated with platinum drugs
EP2155255B1 (en) 2007-05-09 2013-08-14 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
JP2010526917A (ja) * 2007-05-09 2010-08-05 日東電工株式会社 複数種の薬物を有するポリグルタミン酸塩複合体及びポリグルタミン酸塩−アミノ酸複合体
WO2009111271A1 (en) * 2008-03-06 2009-09-11 Nitto Denko Corporation Polymer paclitaxel conjugates and methods for treating cancer
WO2019016208A1 (en) * 2017-07-17 2019-01-24 Technische Universiteit Eindhoven APPLICABLE CHEMICAL COMPOSITION COMPRISING AN AGENT CONJUGATED TO A HYDROPHOBIC PART AND A SUPPORT

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1541436A (en) * 1976-02-02 1979-02-28 Searle & Co Immunological materials
JP2528477B2 (ja) * 1987-09-07 1996-08-28 三共株式会社 高分子制癌剤の増強剤
JPH04500513A (ja) * 1988-08-23 1992-01-30 ジョージタウン・ユニバーシティー 低骨髄毒性マイトマイシン誘導体、その製造方法およびその使用
JPH0762049B2 (ja) * 1991-03-18 1995-07-05 工業技術院長 高分子マイトマイシンｃ誘導体及びその製造方法
JPH05252673A (ja) * 1992-03-05 1993-09-28 Honda Motor Co Ltd 電源装置

Also Published As

Publication number Publication date
GB2282384B (en) 1997-09-03
ATE192933T1 (de) 2000-06-15
DE69424577T2 (de) 2001-02-22
EP0804246B1 (en) 2000-05-17
GB9317213D0 (en) 1993-10-06
GB2282384B8 (en) 1997-09-04
WO1995005200A1 (en) 1995-02-23
EP0804246A1 (en) 1997-11-05
CA2168007C (en) 2001-06-12
CA2168007A1 (en) 1995-02-23
US5738864A (en) 1998-04-14
GB2282384A (en) 1995-04-05
JPH09501674A (ja) 1997-02-18
ES2145832T3 (es) 2000-07-16
DE69424577D1 (de) 2000-06-21
GR3034174T3 (en) 2000-11-30
PT804246E (pt) 2000-08-31

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