BRPI0810717A2 - sulfonato hidroxi de composto de quinona e seus usos - Google Patents
sulfonato hidroxi de composto de quinona e seus usosInfo
- Publication number
- BRPI0810717A2 BRPI0810717A2 BRPI0810717A BRPI0810717A BRPI0810717A2 BR PI0810717 A2 BRPI0810717 A2 BR PI0810717A2 BR PI0810717 A BRPI0810717 A BR PI0810717A BR PI0810717 A BRPI0810717 A BR PI0810717A BR PI0810717 A2 BRPI0810717 A2 BR PI0810717A2
- Authority
- BR
- Brazil
- Prior art keywords
- quinone compound
- hydroxy sulfonate
- sulfonate
- hydroxy
- quinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91497107P | 2007-04-30 | 2007-04-30 | |
PCT/US2008/005656 WO2008134088A1 (en) | 2007-04-30 | 2008-04-30 | Hydroxy sulfonate of quinone compounds and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0810717A2 true BRPI0810717A2 (pt) | 2016-05-24 |
Family
ID=39494644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0810717A BRPI0810717A2 (pt) | 2007-04-30 | 2008-04-30 | sulfonato hidroxi de composto de quinona e seus usos |
Country Status (14)
Country | Link |
---|---|
US (1) | US7790765B2 (pt) |
EP (1) | EP2152686B1 (pt) |
JP (1) | JP2010526072A (pt) |
KR (1) | KR20100017483A (pt) |
CN (1) | CN101687835B (pt) |
AU (1) | AU2008246067B2 (pt) |
BR (1) | BRPI0810717A2 (pt) |
CA (1) | CA2685739C (pt) |
DK (1) | DK2152686T3 (pt) |
ES (1) | ES2532656T3 (pt) |
HK (1) | HK1139411A1 (pt) |
MX (1) | MX2009011822A (pt) |
TW (1) | TWI401081B (pt) |
WO (1) | WO2008134088A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009048251A2 (en) * | 2007-10-11 | 2009-04-16 | Mazence Inc. | Pharmaceutical composition containing micronized particles of naphthoquinone-based compound |
KR101405823B1 (ko) * | 2007-12-24 | 2014-06-12 | 주식회사 케이티앤지생명과학 | 녹내장의 치료 및 예방을 위한 약제 조성물 |
KR20090071829A (ko) * | 2007-12-28 | 2009-07-02 | 주식회사 머젠스 | 신장질환의 치료 및 예방을 위한 약제 조성물 |
EP2649994B1 (de) * | 2011-01-31 | 2017-08-30 | LUCOLAS-M.D. Ltd. | Kombinationen von aromatase inhibitoren und antioxidanzien |
US9343930B2 (en) * | 2012-05-25 | 2016-05-17 | Baldor Electric Company | Segmented stator assembly |
US10246066B2 (en) * | 2014-07-10 | 2019-04-02 | Robert Bosch Gmbh | Motor module and ABS hydraulic unit |
US10450289B2 (en) | 2015-06-08 | 2019-10-22 | University of Pittsburgh—of the Commonwealth System of Higher Education | Substituted β-lapachones for treating cancer |
US11090389B2 (en) | 2016-10-13 | 2021-08-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Mitochondrially targeted PARP inhibitor, and uses thereof |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0040506B1 (en) | 1980-05-21 | 1986-08-20 | Teijin Limited | Reactive polymer and process for the preparation thereof |
US4963565A (en) | 1986-07-30 | 1990-10-16 | National Jewish Center For Immunology And Respiratory Medicine | In vivo treatment of mycobacterial infections with 6-cyclo octylamino-5,8-quinoline quinone |
US5120843A (en) | 1987-04-27 | 1992-06-09 | Upjohn | Pharmaceutically active amines |
FI102273B (fi) | 1989-09-11 | 1998-11-13 | Eisai Co Ltd | Kinonijohdannaiset, niiden valmistaminen ja niiden farmakologinen käyt tö |
JP3111099B2 (ja) | 1991-10-31 | 2000-11-20 | 科学技術振興事業団 | 水溶性高分子化薬剤の製造法 |
US5559156A (en) | 1993-09-30 | 1996-09-24 | Glaxo Wellcome, Inc. | Method for treating animals infected with Babesia spp. |
WO1994004145A1 (en) | 1992-08-21 | 1994-03-03 | Dana Farber Cancer Institute | Treatment of human viral infections |
US5672607A (en) | 1993-01-29 | 1997-09-30 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral naphthoquinone compounds, compositions and uses thereof |
GB2282384B8 (en) | 1993-08-18 | 1997-09-04 | Europ Economic Community | Drug delivery agents incorporating mitomycin |
EP0640609A1 (en) | 1993-08-24 | 1995-03-01 | Ono Pharmaceutical Co., Ltd. | Fused phenol derivatives having inhibitory activity on TXA2 synthetase, and 5-lipoxygenase and scavenging activity on oxygen species |
US5880131A (en) | 1993-10-20 | 1999-03-09 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
US5840900A (en) | 1993-10-20 | 1998-11-24 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
US5763625A (en) | 1995-04-25 | 1998-06-09 | Wisconsin Alumni Research Foundation | Synthesis and use of β-lapachone analogs |
US5674900A (en) | 1995-06-06 | 1997-10-07 | Shaman Pharmaceuticals, Inc. | Terpenoid-type quinones for treatment of diabetes |
US6245807B1 (en) | 1995-08-24 | 2001-06-12 | Dana-Farber Cancer Institute | Treatment of human prostate disease |
US5824700A (en) | 1996-02-20 | 1998-10-20 | Wisconsin Alumni Research Foundation | Ortho-quinone derivatives novel synthesis therefor and their use in the inhibition of neoplastic cell growth |
SI0932399T1 (sl) | 1996-03-12 | 2006-10-31 | Pg Txl Co Lp | Vodotopna paklitakselna predzdravila |
AU2411197A (en) | 1996-04-30 | 1997-11-19 | Affymax Technologies N.V. | Methods for the synthesis of fmoc protected amines |
DE60031268T2 (de) | 1999-04-14 | 2007-05-24 | Dana-Farber Cancer Institute, Inc., Boston | Verfahren und zusammansetzung zur behandlung von krebs |
JP2002543163A (ja) | 1999-04-30 | 2002-12-17 | スリル バイオメディカル コーポレイション | 癌および前立腺疾患のための治療としての結合体 |
US6376470B1 (en) | 1999-09-23 | 2002-04-23 | Enzon, Inc. | Polymer conjugates of ara-C and ara-C derivatives |
HUP0203123A3 (en) | 1999-10-12 | 2004-12-28 | Cell Therapeutics Inc Seattle | Process for preparation of polyglutamate-therapeutic agent conjugates |
CA2402643A1 (en) | 2000-03-17 | 2001-09-27 | Cell Therapeutics, Inc. | Polyglutamic acid-camptothecin conjugates and methods of preparation |
JP4244141B2 (ja) | 2000-11-07 | 2009-03-25 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 血液腫瘍および血液癌を処置する方法 |
US6458974B1 (en) | 2001-01-25 | 2002-10-01 | Cyclis Pharmaceuticals, Inc. | Synthesis of β-lapachone and its intermediates |
US6962944B2 (en) | 2001-07-31 | 2005-11-08 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
US7074824B2 (en) | 2001-07-31 | 2006-07-11 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
CZ293787B6 (cs) | 2001-12-20 | 2004-07-14 | Zentiva, A.S. | pH senzitivní polymerní konjugáty antracyklinového kancerostatika pro cílenou terapii |
US6890950B2 (en) | 2002-04-23 | 2005-05-10 | Case Western Reserve University | Lapachone delivery systems, compositions and uses related thereto |
US6608076B1 (en) | 2002-05-16 | 2003-08-19 | Enzon, Inc. | Camptothecin derivatives and polymeric conjugates thereof |
WO2004006849A2 (en) | 2002-07-15 | 2004-01-22 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
TW200510367A (en) | 2002-11-18 | 2005-03-16 | Arqule Inc | Novel lapachone compounds, their preparation, and the use thereof |
WO2005082356A2 (en) | 2004-02-20 | 2005-09-09 | Arqule, Inc. | Use of beta-lapachone for the treatment of lung cancer |
JP2007523191A (ja) | 2004-02-20 | 2007-08-16 | アークル・インコーポレーテツド | 血液腫瘍の治療のためのβ−ラパコンの使用 |
US8614228B2 (en) | 2004-08-11 | 2013-12-24 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
CA2583700A1 (en) | 2004-08-11 | 2006-02-23 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
WO2006128120A2 (en) | 2005-05-26 | 2006-11-30 | Arqule, Inc. | Novel lapachone compounds and methods of use thereof |
-
2008
- 2008-04-30 EP EP08754188.4A patent/EP2152686B1/en active Active
- 2008-04-30 KR KR1020097024913A patent/KR20100017483A/ko not_active Application Discontinuation
- 2008-04-30 BR BRPI0810717A patent/BRPI0810717A2/pt not_active Application Discontinuation
- 2008-04-30 CN CN200880022708.XA patent/CN101687835B/zh active Active
- 2008-04-30 JP JP2010506326A patent/JP2010526072A/ja not_active Withdrawn
- 2008-04-30 TW TW097115955A patent/TWI401081B/zh active
- 2008-04-30 AU AU2008246067A patent/AU2008246067B2/en active Active
- 2008-04-30 DK DK08754188.4T patent/DK2152686T3/en active
- 2008-04-30 CA CA2685739A patent/CA2685739C/en active Active
- 2008-04-30 US US12/150,914 patent/US7790765B2/en active Active
- 2008-04-30 ES ES08754188.4T patent/ES2532656T3/es active Active
- 2008-04-30 WO PCT/US2008/005656 patent/WO2008134088A1/en active Application Filing
- 2008-04-30 MX MX2009011822A patent/MX2009011822A/es active IP Right Grant
-
2010
- 2010-06-24 HK HK10106231.4A patent/HK1139411A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
TW200913986A (en) | 2009-04-01 |
KR20100017483A (ko) | 2010-02-16 |
US7790765B2 (en) | 2010-09-07 |
HK1139411A1 (en) | 2010-09-17 |
EP2152686B1 (en) | 2014-12-17 |
ES2532656T3 (es) | 2015-03-30 |
AU2008246067B2 (en) | 2011-10-20 |
MX2009011822A (es) | 2010-01-14 |
CN101687835B (zh) | 2015-08-19 |
TWI401081B (zh) | 2013-07-11 |
WO2008134088A1 (en) | 2008-11-06 |
US20090028952A1 (en) | 2009-01-29 |
CA2685739C (en) | 2016-06-14 |
EP2152686A1 (en) | 2010-02-17 |
DK2152686T3 (en) | 2015-01-12 |
CN101687835A (zh) | 2010-03-31 |
JP2010526072A (ja) | 2010-07-29 |
AU2008246067A1 (en) | 2008-11-06 |
CA2685739A1 (en) | 2008-11-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |