DK0778844T3 - Funktionelle terpyridinkomplekser, fremgangsmåder til fremstilling deraf og oligonukleotidkonjugater med terpyridinmetalkomplekser - Google Patents

Funktionelle terpyridinkomplekser, fremgangsmåder til fremstilling deraf og oligonukleotidkonjugater med terpyridinmetalkomplekser

Info

Publication number
DK0778844T3
DK0778844T3 DK95931224T DK95931224T DK0778844T3 DK 0778844 T3 DK0778844 T3 DK 0778844T3 DK 95931224 T DK95931224 T DK 95931224T DK 95931224 T DK95931224 T DK 95931224T DK 0778844 T3 DK0778844 T3 DK 0778844T3
Authority
DK
Denmark
Prior art keywords
terpyridine
complexes
pct
preparation
functional
Prior art date
Application number
DK95931224T
Other languages
English (en)
Inventor
Dieter Huesken
Robert Haener
Jonathan Hall
Uwe Pieles
Heinz Moser
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0778844T3 publication Critical patent/DK0778844T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/40Rare earth chelates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK95931224T 1994-09-02 1995-08-30 Funktionelle terpyridinkomplekser, fremgangsmåder til fremstilling deraf og oligonukleotidkonjugater med terpyridinmetalkomplekser DK0778844T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH269394 1994-09-02
PCT/EP1995/003409 WO1996007668A1 (de) 1994-09-02 1995-08-30 Funktionelle terpyridin-metallkomplexe, verfahren zu deren herstellung und oligonukleotid-konjugate mit terpyridin-metallkomplexen

Publications (1)

Publication Number Publication Date
DK0778844T3 true DK0778844T3 (da) 2003-03-31

Family

ID=4239459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95931224T DK0778844T3 (da) 1994-09-02 1995-08-30 Funktionelle terpyridinkomplekser, fremgangsmåder til fremstilling deraf og oligonukleotidkonjugater med terpyridinmetalkomplekser

Country Status (15)

Country Link
US (1) US5925744A (da)
EP (1) EP0778844B1 (da)
JP (1) JPH10505354A (da)
AT (1) ATE229969T1 (da)
AU (1) AU695749B2 (da)
CA (1) CA2197788A1 (da)
CY (1) CY2435B1 (da)
DE (1) DE59510515D1 (da)
DK (1) DK0778844T3 (da)
ES (1) ES2191060T3 (da)
FI (1) FI970740A (da)
HU (1) HU217774B (da)
NO (1) NO316866B1 (da)
PT (1) PT778844E (da)
WO (1) WO1996007668A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000514799A (ja) * 1996-07-03 2000-11-07 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ オリゴヌクレオチドリンカーおよび固定化および結合オリゴヌクレオチドを用いる技術
US6376664B1 (en) * 1999-03-17 2002-04-23 The Ohio State University Cyclic bis-benzimidazole ligands and metal complexes thereof
US6407089B1 (en) 1999-12-23 2002-06-18 Trinapco Inc. Triazatrinaphthyrins and the use thereof
JP4758582B2 (ja) * 1999-12-23 2011-08-31 トリナプコ インコーポレイテッド トリアザトリナフチリンおよびその用途
GB0007764D0 (en) * 2000-03-30 2000-05-17 Bp Chem Int Ltd Polymerisation catalyst
FR2810406B1 (fr) * 2000-06-15 2002-09-20 Cis Bio Int Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence
WO2007125173A2 (en) 2006-05-03 2007-11-08 Baltic Technology Development, Ltd. Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease
CA2724552C (en) 2008-05-27 2018-10-09 Dako Denmark A/S Compositions and methods for detection of chromosomal aberrations with hybridization buffers comprising a polar aprotic solvent
WO2010097655A1 (en) 2009-02-26 2010-09-02 Dako Denmark A/S Compositions and methods for rna hybridization applications
US20110151457A1 (en) 2009-12-22 2011-06-23 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
EP2761028A1 (en) 2011-09-30 2014-08-06 Dako Denmark A/S Hybridization compositions and methods using formamide
EP3252173A1 (en) 2011-10-21 2017-12-06 Dako Denmark A/S Hybridization compositions and methods
CN114315702A (zh) * 2022-02-11 2022-04-12 南京邮电大学 一种基于低维镧系金属配合物X射线激发闪烁体Eu-TPC及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806463A (en) * 1986-05-23 1989-02-21 Worcester Foundation For Experimental Biology Inhibition of HTLV-III by exogenous oligonucleotides
EP0266099A3 (en) * 1986-10-28 1990-09-19 The Johns Hopkins University Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids
DE68925278T2 (de) * 1988-02-26 1996-09-19 Worcester Found Ex Biology Hemmung von htlv-iii durch exogene oligonukleotide
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
US5760191A (en) * 1993-02-05 1998-06-02 Nycomed Imaging As Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods

Also Published As

Publication number Publication date
ATE229969T1 (de) 2003-01-15
NO970886D0 (no) 1997-02-27
NO316866B1 (no) 2004-06-07
ES2191060T3 (es) 2003-09-01
US5925744A (en) 1999-07-20
FI970740A0 (fi) 1997-02-21
EP0778844B1 (de) 2002-12-18
CY2435B1 (en) 2004-11-12
PT778844E (pt) 2003-04-30
AU695749B2 (en) 1998-08-20
HUT77933A (hu) 1998-11-30
DE59510515D1 (de) 2003-01-30
CA2197788A1 (en) 1996-03-14
WO1996007668A1 (de) 1996-03-14
AU3474495A (en) 1996-03-27
NO970886L (no) 1997-04-25
EP0778844A1 (de) 1997-06-18
FI970740A (fi) 1997-02-21
HU217774B (hu) 2000-04-28
JPH10505354A (ja) 1998-05-26

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