MX9605716A - Metodos y composiciones para el tratamiento de restenosis y cancer usando ribozimas. - Google Patents

Metodos y composiciones para el tratamiento de restenosis y cancer usando ribozimas.

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Publication number
MX9605716A
MX9605716A MX9605716A MX9605716A MX9605716A MX 9605716 A MX9605716 A MX 9605716A MX 9605716 A MX9605716 A MX 9605716A MX 9605716 A MX9605716 A MX 9605716A MX 9605716 A MX9605716 A MX 9605716A
Authority
MX
Mexico
Prior art keywords
ribozymes
restenosis
cancer
compositions
treatment
Prior art date
Application number
MX9605716A
Other languages
English (en)
Inventor
Dan T Stinchcomb
Kenneth Draper
James Mcswiggen
Thale Jarvis
Original Assignee
Ribozyme Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribozyme Pharm Inc filed Critical Ribozyme Pharm Inc
Publication of MX9605716A publication Critical patent/MX9605716A/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
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    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
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    • A61K38/00—Medicinal preparations containing peptides
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Abstract

Una molécula de ácido nucleico enzimático que difiere ARN c-myb, en donde los brazos de enlace de dicho ácido nucleico contienen secuencias complementarias a las secuencias definidas en los cuadros II, XII-XXIV.
MX9605716A 1994-05-18 1995-05-18 Metodos y composiciones para el tratamiento de restenosis y cancer usando ribozimas. MX9605716A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24546694A 1994-05-18 1994-05-18
US08/373,124 US5646042A (en) 1992-08-26 1995-01-13 C-myb targeted ribozymes
PCT/US1995/006368 WO1995031541A2 (en) 1994-05-18 1995-05-18 Methods and compositions for treatment of restenosis and cancer using ribozymes

Publications (1)

Publication Number Publication Date
MX9605716A true MX9605716A (es) 1998-05-31

Family

ID=26937257

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605716A MX9605716A (es) 1994-05-18 1995-05-18 Metodos y composiciones para el tratamiento de restenosis y cancer usando ribozimas.

Country Status (7)

Country Link
US (2) US5646042A (es)
EP (1) EP0763106A1 (es)
JP (1) JPH10500309A (es)
AU (1) AU2642295A (es)
CA (1) CA2190513A1 (es)
MX (1) MX9605716A (es)
WO (1) WO1995031541A2 (es)

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