FI970740A - Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa - Google Patents

Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa Download PDF

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Publication number
FI970740A
FI970740A FI970740A FI970740A FI970740A FI 970740 A FI970740 A FI 970740A FI 970740 A FI970740 A FI 970740A FI 970740 A FI970740 A FI 970740A FI 970740 A FI970740 A FI 970740A
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FI
Finland
Prior art keywords
terpyridine
metal complexes
pct
preparation
functional
Prior art date
Application number
FI970740A
Other languages
English (en)
Swedish (sv)
Other versions
FI970740A0 (fi
Inventor
Robert Haener
Jonathan Hall
Dieter Huesken
Uwe Pieles
Heinz Moser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI970740A publication Critical patent/FI970740A/fi
Publication of FI970740A0 publication Critical patent/FI970740A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/40Rare earth chelates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI970740A 1994-09-02 1997-02-21 Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa FI970740A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH269394 1994-09-02
PCT/EP1995/003409 WO1996007668A1 (de) 1994-09-02 1995-08-30 Funktionelle terpyridin-metallkomplexe, verfahren zu deren herstellung und oligonukleotid-konjugate mit terpyridin-metallkomplexen

Publications (2)

Publication Number Publication Date
FI970740A true FI970740A (fi) 1997-02-21
FI970740A0 FI970740A0 (fi) 1997-02-21

Family

ID=4239459

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970740A FI970740A0 (fi) 1994-09-02 1997-02-21 Funktionaaliset terpyridiini-metallikompleksit, menetelmät niiden valmistamiseksi ja oligonukleotidikonjugaatit terpyridiini-metallikompleksien kanssa

Country Status (15)

Country Link
US (1) US5925744A (fi)
EP (1) EP0778844B1 (fi)
JP (1) JPH10505354A (fi)
AT (1) ATE229969T1 (fi)
AU (1) AU695749B2 (fi)
CA (1) CA2197788A1 (fi)
CY (1) CY2435B1 (fi)
DE (1) DE59510515D1 (fi)
DK (1) DK0778844T3 (fi)
ES (1) ES2191060T3 (fi)
FI (1) FI970740A0 (fi)
HU (1) HU217774B (fi)
NO (1) NO316866B1 (fi)
PT (1) PT778844E (fi)
WO (1) WO1996007668A1 (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2259493A1 (en) * 1996-07-03 1998-01-08 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
US6376664B1 (en) * 1999-03-17 2002-04-23 The Ohio State University Cyclic bis-benzimidazole ligands and metal complexes thereof
US6407089B1 (en) 1999-12-23 2002-06-18 Trinapco Inc. Triazatrinaphthyrins and the use thereof
KR100747613B1 (ko) * 1999-12-23 2007-08-09 트리나프코 인크. 트리아자트리나프티린 및 이의 용도
GB0007764D0 (en) * 2000-03-30 2000-05-17 Bp Chem Int Ltd Polymerisation catalyst
FR2810406B1 (fr) * 2000-06-15 2002-09-20 Cis Bio Int Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence
JP2009535383A (ja) 2006-05-03 2009-10-01 バルティック テクロノジー デヴェロプメント,リミテッド 強く結合した塩基で修飾されたオリゴヌクレオチドと人工ヌクレアーゼを組み合わせたアンチセンス作用物質
EP2285979B2 (en) 2008-05-27 2020-02-19 Dako Denmark A/S Hybridization compositions and methods
US9303287B2 (en) 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
WO2011087707A1 (en) 2009-12-22 2011-07-21 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
EP2761028A1 (en) 2011-09-30 2014-08-06 Dako Denmark A/S Hybridization compositions and methods using formamide
EP2768974B1 (en) 2011-10-21 2017-07-19 Dako Denmark A/S Hybridization compositions and methods
CN114315702A (zh) * 2022-02-11 2022-04-12 南京邮电大学 一种基于低维镧系金属配合物X射线激发闪烁体Eu-TPC及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806463A (en) * 1986-05-23 1989-02-21 Worcester Foundation For Experimental Biology Inhibition of HTLV-III by exogenous oligonucleotides
EP0266099A3 (en) * 1986-10-28 1990-09-19 The Johns Hopkins University Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids
JPH04501052A (ja) * 1988-02-26 1992-02-27 ザ・ウスター・フアウンデーシヨン・フオー・バイオメデイカル・リサーチ 外来性オリゴヌクレオチドによるhtlv―3の抑制
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
US5760191A (en) * 1993-02-05 1998-06-02 Nycomed Imaging As Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods

Also Published As

Publication number Publication date
EP0778844B1 (de) 2002-12-18
NO316866B1 (no) 2004-06-07
DK0778844T3 (da) 2003-03-31
US5925744A (en) 1999-07-20
AU3474495A (en) 1996-03-27
DE59510515D1 (de) 2003-01-30
EP0778844A1 (de) 1997-06-18
AU695749B2 (en) 1998-08-20
HU217774B (hu) 2000-04-28
NO970886L (no) 1997-04-25
CY2435B1 (en) 2004-11-12
ATE229969T1 (de) 2003-01-15
JPH10505354A (ja) 1998-05-26
NO970886D0 (no) 1997-02-27
CA2197788A1 (en) 1996-03-14
FI970740A0 (fi) 1997-02-21
ES2191060T3 (es) 2003-09-01
WO1996007668A1 (de) 1996-03-14
HUT77933A (hu) 1998-11-30
PT778844E (pt) 2003-04-30

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