MX9603891A - Compuestos de 9-desoxotaxano. - Google Patents

Compuestos de 9-desoxotaxano.

Info

Publication number
MX9603891A
MX9603891A MX9603891A MX9603891A MX9603891A MX 9603891 A MX9603891 A MX 9603891A MX 9603891 A MX9603891 A MX 9603891A MX 9603891 A MX9603891 A MX 9603891A MX 9603891 A MX9603891 A MX 9603891A
Authority
MX
Mexico
Prior art keywords
compounds
deoxotaxane
oxygenated
paclitaxel
hydrogen
Prior art date
Application number
MX9603891A
Other languages
English (en)
Other versions
MXPA96003891A (es
Inventor
Larry L Klein
Clinton M Yeung
Leping Li
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX9603891A publication Critical patent/MX9603891A/es
Publication of MXPA96003891A publication Critical patent/MXPA96003891A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Compuestos que tienen la formula (i) en donde -OR1 comprende alcanoilo o la cadena lateral C-13 de paclitaxel; R2, R3 y R4 pueden ser oxigenadas o hidrogeno en varias combinaciones; y R4 y R5 son grupos acilo, así como un procedimiento para la preparacion de los mismos, composiciones farmacéuticas que contienen los compuestos anteriores, y un método para utilizarse en la inhibicion del crecimiento de tumores.
MXPA/A/1996/003891A 1994-03-09 1995-03-01 Compuestos de 9-desoxotaxano MXPA96003891A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/208,509 US5440056A (en) 1992-04-17 1994-03-09 9-deoxotaxane compounds
US08208509 1994-03-09
PCT/US1995/002524 WO1995024402A1 (en) 1994-03-09 1995-03-01 9-deoxotaxane compounds

Publications (2)

Publication Number Publication Date
MX9603891A true MX9603891A (es) 1997-07-31
MXPA96003891A MXPA96003891A (es) 1997-12-01

Family

ID=

Also Published As

Publication number Publication date
ATE201019T1 (de) 2001-05-15
EP0749432B1 (en) 2001-05-09
AU688946B2 (en) 1998-03-19
PH31271A (en) 1998-06-18
IL112880A0 (en) 1995-06-29
GR3036286T3 (en) 2001-10-31
CA2182103A1 (en) 1995-09-14
DK0749432T3 (da) 2001-07-30
PT749432E (pt) 2001-09-28
US5616740A (en) 1997-04-01
JPH09511235A (ja) 1997-11-11
DE69520880D1 (de) 2001-06-13
ES2158093T3 (es) 2001-09-01
US5440056A (en) 1995-08-08
EP0749432A1 (en) 1996-12-27
WO1995024402A1 (en) 1995-09-14
KR970701708A (ko) 1997-04-12
AU3104795A (en) 1995-09-25
DE69520880T2 (de) 2001-12-20

Similar Documents

Publication Publication Date Title
PH31271A (en) 9-Deoxotaxane compounds.
AP9701019A0 (en) Phenylamino-substituted tricycle derivatives.
PL349028A1 (en) Cancer treatment composition and method using natural plant essential oils
GEP20032896B (en) 4-Aminothiazole Derivatives, Containing Them Pharmaceutical Compositions Inhibiting Cyclin-Dependent Kinases and Methods for Treatment
DE69104991T2 (de) Mometason-furoate-monohydrat, verfahren zu seiner herstellung und das enthaltende pharmazeutische zusammensetzungen.
BG103947A (en) Derivatives of 9-oxymerythromycin
GEP20032953B (en) Antitumor Agents
TW365604B (en) Anthracyclinone derivatives
PL313078A1 (en) Novel bis-naphtalimides for use in treating carcinoma
MX9601635A (es) Derivados de antraciclina.
GEP20032975B (en) Echinocandin Derivatives, Preparation Method and Pharmaceutical Composition
ZA876542B (en) Novel 3-methylphtalimides
AP9901567A0 (en) Steroids substituted in composition 11, their preparation process, their use as medicaments and the pharmaceutical compounds containing them.
ES8601200A1 (es) Un procedimiento para preparar compuestos de 3-(2-haloetil)-4-oxopirazolo-(5, 1-d)-1, 2, 3, 5-tetrazin-8-carboxamida
DE3576154D1 (de) 5-cyanopyridine-2-diazohydroxide, basische salze und verfahren zu ihrer herstellung und anwendung.
DE69116423D1 (de) 3'-Deamino-4'-deoxy-4'-amino-8-fluoranthracycline und Verfahren zu ihrer Herstellung
AU1032197A (en) New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds
ES8702373A1 (es) Un procedimiento para preparar diazohidroxidos de pirazina.
IL114646A (en) Pharmaceutical compositions containing phenylurea derivatives for inhibiting leukotriene biosynthesis
MX9802933A (es) Derivados novedosos de amina de 2", 3"-didesoxiglicosidos de epipodofilotoxina, metodo de preparacion de los mismos y uso de los mismos con un farmaco y para tratamientos anticancer.
IL117734A (en) Anellated beta-carbolines their preparation and pharmaceutical compositions containing them
HU9201553D0 (en) New carbamide derivatives, process for their production and for the production of medical compositions containing them

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees