AU1032197A - New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds - Google Patents

New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds

Info

Publication number
AU1032197A
AU1032197A AU10321/97A AU1032197A AU1032197A AU 1032197 A AU1032197 A AU 1032197A AU 10321/97 A AU10321/97 A AU 10321/97A AU 1032197 A AU1032197 A AU 1032197A AU 1032197 A AU1032197 A AU 1032197A
Authority
AU
Australia
Prior art keywords
compounds
processes
production
pharmaceutical agents
agents containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU10321/97A
Other versions
AU729334B2 (en
Inventor
Angelika Esswein
Walter-Gunar Friebe
Lothar Kling
Ulrike Leser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of AU1032197A publication Critical patent/AU1032197A/en
Assigned to ROCHE DIAGNOSTICS GMBH reassignment ROCHE DIAGNOSTICS GMBH Amend patent request/document other than specification (104) Assignors: BOEHRINGER MANNHEIM GMBH
Application granted granted Critical
Publication of AU729334B2 publication Critical patent/AU729334B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton

Abstract

Compounds of formula Iin whichR1 denotes hydrogen or methylR2 denotes lower straight-chained or branched alkyl with 1 to 10 carbon atomsR3 denotes hydrogen or lower alkyln denotes 0-12R4 denotes alkyl, alkenyl or alkinyl with 6 to 24 carbon atoms,processes for the production thereof as well as pharmaceutical agents containing these compounds for the treatment of osteoporosis.
AU10321/97A 1995-11-30 1996-11-26 New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds Ceased AU729334B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19544635A DE19544635A1 (en) 1995-11-30 1995-11-30 Novel amino alcohol derivatives, processes for their preparation and medicaments containing these compounds
DE19544635 1995-11-30
PCT/EP1996/005212 WO1997019909A1 (en) 1995-11-30 1996-11-26 Amino alcohol derivatives, methods of producing said derivatives and medicaments containing them

Publications (2)

Publication Number Publication Date
AU1032197A true AU1032197A (en) 1997-06-19
AU729334B2 AU729334B2 (en) 2001-02-01

Family

ID=7778803

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10321/97A Ceased AU729334B2 (en) 1995-11-30 1996-11-26 New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds

Country Status (17)

Country Link
US (1) US6444832B1 (en)
EP (1) EP0865422B1 (en)
JP (1) JP2000502056A (en)
KR (1) KR100490005B1 (en)
CN (1) CN1154632C (en)
AT (1) ATE203010T1 (en)
AU (1) AU729334B2 (en)
BR (1) BR9611805A (en)
DE (2) DE19544635A1 (en)
DK (1) DK0865422T3 (en)
ES (1) ES2160847T3 (en)
GR (1) GR3036868T3 (en)
MX (1) MX9804290A (en)
PT (1) PT865422E (en)
TR (1) TR199800974T2 (en)
WO (1) WO1997019909A1 (en)
ZA (1) ZA9610040B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911553B1 (en) 1997-10-02 2005-06-28 Roche Diagnostics Gmbh Osteoblast-specific mitogens and drugs containing such compounds
EP0906759A1 (en) * 1997-10-02 1999-04-07 Roche Diagnostics GmbH Novel osteoblastic specific mitogenes: process for their preparation and drugs containing these compounds
WO2009109973A2 (en) * 2008-03-04 2009-09-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compounds and methods of treating obesity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795611A (en) * 1970-12-28 1974-03-05 Colgate Palmolive Co Fabric softening compositions
US3846449A (en) * 1971-08-31 1974-11-05 Us Agriculture N-substituted fatty acid amide lubricants
DE3309948A1 (en) * 1982-03-30 1983-10-13 Sandoz-Patent-GmbH, 7850 Lörrach LOST LOW-AVOIDING CONNECTIONS FOR HOLE-PROCESSING LIQUIDS
IL103932A (en) * 1992-11-30 1997-02-18 Yissum Res & Dev Fatty acid and pharmaceutical compositions containing them
DE69412538T2 (en) * 1993-05-18 1998-12-24 Takeda Chemical Industries Ltd Benzopyran derivatives and their use
AU7957494A (en) * 1993-09-20 1995-04-10 Waters Corporation Chiral surfactants and methods for their use in chiral separations

Also Published As

Publication number Publication date
AU729334B2 (en) 2001-02-01
ES2160847T3 (en) 2001-11-16
BR9611805A (en) 1999-02-17
JP2000502056A (en) 2000-02-22
MX9804290A (en) 1998-09-30
KR19990071788A (en) 1999-09-27
CN1154632C (en) 2004-06-23
DE19544635A1 (en) 1997-06-05
GR3036868T3 (en) 2002-01-31
DE59607280D1 (en) 2001-08-16
PT865422E (en) 2001-12-28
ZA9610040B (en) 1998-06-12
EP0865422A1 (en) 1998-09-23
DK0865422T3 (en) 2001-10-22
EP0865422B1 (en) 2001-07-11
WO1997019909A1 (en) 1997-06-05
US6444832B1 (en) 2002-09-03
TR199800974T2 (en) 1998-08-21
KR100490005B1 (en) 2005-12-21
ATE203010T1 (en) 2001-07-15
CN1207724A (en) 1999-02-10

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Legal Events

Date Code Title Description
SREP Specification republished
FGA Letters patent sealed or granted (standard patent)