DK0769945T3 - Brug af 2-phenyl-3-aroylbenzothiophenderivater til fremstilling af et medikament til behandling af knogler og knoglebrud - Google Patents

Brug af 2-phenyl-3-aroylbenzothiophenderivater til fremstilling af et medikament til behandling af knogler og knoglebrud

Info

Publication number
DK0769945T3
DK0769945T3 DK95930874T DK95930874T DK0769945T3 DK 0769945 T3 DK0769945 T3 DK 0769945T3 DK 95930874 T DK95930874 T DK 95930874T DK 95930874 T DK95930874 T DK 95930874T DK 0769945 T3 DK0769945 T3 DK 0769945T3
Authority
DK
Denmark
Prior art keywords
bone
phenyl
medicament
manufacture
treatment
Prior art date
Application number
DK95930874T
Other languages
Danish (da)
English (en)
Inventor
George Joseph Cullinan
Masahiko Sato
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0769945T3 publication Critical patent/DK0769945T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95930874T 1994-08-22 1995-08-21 Brug af 2-phenyl-3-aroylbenzothiophenderivater til fremstilling af et medikament til behandling af knogler og knoglebrud DK0769945T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/294,130 US5502074A (en) 1994-08-22 1994-08-22 Benzothiophenes for bone healing and fracture repair
PCT/US1995/010618 WO1996005825A1 (en) 1994-08-22 1995-08-21 Methods for bone healing and fracture repair

Publications (1)

Publication Number Publication Date
DK0769945T3 true DK0769945T3 (da) 2003-06-10

Family

ID=23132010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930874T DK0769945T3 (da) 1994-08-22 1995-08-21 Brug af 2-phenyl-3-aroylbenzothiophenderivater til fremstilling af et medikament til behandling af knogler og knoglebrud

Country Status (20)

Country Link
US (1) US5502074A (es)
EP (1) EP0769945B1 (es)
JP (1) JPH10504578A (es)
KR (1) KR970705385A (es)
AT (1) ATE240101T1 (es)
AU (1) AU701946B2 (es)
CA (1) CA2198012A1 (es)
CZ (1) CZ51997A3 (es)
DE (1) DE69530771T2 (es)
DK (1) DK0769945T3 (es)
ES (1) ES2197207T3 (es)
FI (1) FI970715A0 (es)
HU (1) HUT76855A (es)
IL (1) IL115016A (es)
MX (1) MX9701332A (es)
NO (1) NO970785L (es)
PH (1) PH31620A (es)
PT (1) PT769945E (es)
WO (1) WO1996005825A1 (es)
ZA (1) ZA956989B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856340A (en) 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
ES2187195T3 (es) 1998-09-11 2003-05-16 Gerhard Dr Schmidmaier Implantes biologicamente activos.
ATE301129T1 (de) 1999-05-04 2005-08-15 Strakan Int Ltd Androgen glykoside und die androgenische aktivität davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
DE4122484A1 (de) * 1991-07-06 1993-01-07 Teves Gmbh Alfred Schaltungsanordnung zur erkennung von radsensordefekten
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
TW303299B (es) * 1993-07-22 1997-04-21 Lilly Co Eli

Also Published As

Publication number Publication date
DE69530771T2 (de) 2004-03-11
ZA956989B (en) 1997-02-21
NO970785D0 (no) 1997-02-20
IL115016A (en) 1999-09-22
FI970715A (fi) 1997-02-20
ES2197207T3 (es) 2004-01-01
WO1996005825A1 (en) 1996-02-29
PT769945E (pt) 2003-09-30
EP0769945B1 (en) 2003-05-14
FI970715A0 (fi) 1997-02-20
AU3409795A (en) 1996-03-14
CA2198012A1 (en) 1996-02-29
AU701946B2 (en) 1999-02-11
DE69530771D1 (de) 2003-06-18
ATE240101T1 (de) 2003-05-15
HUT76855A (en) 1997-12-29
EP0769945A1 (en) 1997-05-02
JPH10504578A (ja) 1998-05-06
IL115016A0 (en) 1995-12-08
US5502074A (en) 1996-03-26
NO970785L (no) 1997-02-20
CZ51997A3 (en) 1997-08-13
KR970705385A (ko) 1997-10-09
PH31620A (en) 1999-01-12
MX9701332A (es) 1997-05-31
EP0769945A4 (en) 1997-09-03

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