DK0764157T3 - Benzopyraner og deres anvendelse som terapeutiske midler - Google Patents

Benzopyraner og deres anvendelse som terapeutiske midler

Info

Publication number
DK0764157T3
DK0764157T3 DK95921798T DK95921798T DK0764157T3 DK 0764157 T3 DK0764157 T3 DK 0764157T3 DK 95921798 T DK95921798 T DK 95921798T DK 95921798 T DK95921798 T DK 95921798T DK 0764157 T3 DK0764157 T3 DK 0764157T3
Authority
DK
Denmark
Prior art keywords
benzopyrans
therapeutic agents
therapeutic
agents
Prior art date
Application number
DK95921798T
Other languages
Danish (da)
English (en)
Inventor
Wai Ngor Chan
Helen Kate Ann Morgan
Mervyn Thompson
John Morris Evans
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9411632A external-priority patent/GB9411632D0/en
Priority claimed from GB9411798A external-priority patent/GB9411798D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of DK0764157T3 publication Critical patent/DK0764157T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
DK95921798T 1994-06-10 1995-05-31 Benzopyraner og deres anvendelse som terapeutiske midler DK0764157T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9411632A GB9411632D0 (en) 1994-06-10 1994-06-10 Novel treatment
GB9411798A GB9411798D0 (en) 1994-06-13 1994-06-13 Novel treatment
PCT/EP1995/002076 WO1995034545A1 (en) 1994-06-10 1995-05-31 Benzopyrans and their use as therapeutic agents

Publications (1)

Publication Number Publication Date
DK0764157T3 true DK0764157T3 (da) 2002-04-22

Family

ID=26305044

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95921798T DK0764157T3 (da) 1994-06-10 1995-05-31 Benzopyraner og deres anvendelse som terapeutiske midler
DK01200801T DK1114821T3 (da) 1994-06-10 1995-05-31 Benzopyraner og disses anvendelse som terapeutiske midler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01200801T DK1114821T3 (da) 1994-06-10 1995-05-31 Benzopyraner og disses anvendelse som terapeutiske midler

Country Status (29)

Country Link
US (1) US5760074A (no)
EP (2) EP0764157B1 (no)
JP (2) JP3575767B2 (no)
KR (1) KR100397721B1 (no)
CN (2) CN1234702C (no)
AP (1) AP714A (no)
AT (2) ATE211469T1 (no)
AU (1) AU701060B2 (no)
BG (1) BG63339B1 (no)
BR (1) BR9507980A (no)
CA (1) CA2192480C (no)
CY (1) CY2508B1 (no)
CZ (1) CZ286081B6 (no)
DE (2) DE69531801T2 (no)
DK (2) DK0764157T3 (no)
ES (2) ES2170798T3 (no)
FI (1) FI120686B (no)
HK (2) HK1001286A1 (no)
HU (1) HUT76136A (no)
NO (1) NO315651B1 (no)
NZ (1) NZ287872A (no)
OA (1) OA10593A (no)
PL (1) PL188134B1 (no)
PT (2) PT764157E (no)
RO (1) RO113463B1 (no)
SG (1) SG67930A1 (no)
SI (2) SI0764157T1 (no)
SK (1) SK281456B6 (no)
WO (1) WO1995034545A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010021780A1 (en) * 1992-12-11 2001-09-13 Smithkline Beecham P.L.C. Pharmaceutical composition containing bicyclic type compounds
GB9411635D0 (en) * 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
US6492415B2 (en) * 1996-09-18 2002-12-10 Smithkline Beecham P.L.C. Use of benzopyranols to treat neurological disorders
GB9619492D0 (en) * 1996-09-18 1996-10-30 Smithkline Beecham Plc Novel treatment
GB9726543D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel compositions
GB9813949D0 (en) * 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
ZA200708445B (en) * 2005-04-04 2009-03-25 Takeda Pharmaceutical Preventive or remedy for depression or anxiety neurosis
US20130281524A1 (en) * 2008-06-05 2013-10-24 Peter Blower Novel treatments
EP2296646A2 (en) * 2008-06-05 2011-03-23 Minster Research Limited Novel treatments
MX2012006352A (es) * 2009-12-03 2012-06-27 Proximagen Ltd Tratamiento de alodinia e hiperalgesia.
CA2782631A1 (en) 2009-12-03 2011-06-09 Proximagen Ltd Treatment of infectious diseases
AU2013285164A1 (en) 2012-07-03 2015-01-22 Proximagen Limited Pro-drug compounds
GB201304814D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds
GB201322932D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Pro-drug compounds
GB201322934D0 (en) 2013-12-23 2014-02-12 Proximagen Ltd Prodrug compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
GB9112721D0 (en) * 1991-06-13 1991-07-31 Smithkline Beecham Plc Novel treatment
EP0673373A1 (en) * 1992-12-11 1995-09-27 Smithkline Beecham Plc Bicyclic compounds with pharmaceutical activity
EP0673374B1 (en) * 1992-12-11 2000-03-01 Smithkline Beecham Plc Pharmaceutical composition containing bicyclic type compounds
US5536718A (en) * 1995-01-17 1996-07-16 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists

Also Published As

Publication number Publication date
HK1039115B (zh) 2004-08-13
JPH10501251A (ja) 1998-02-03
NZ287872A (en) 1998-05-27
PT764157E (pt) 2002-06-28
HUT76136A (en) 1997-06-30
BR9507980A (pt) 1997-08-12
SG67930A1 (en) 1999-10-19
FI120686B (fi) 2010-01-29
WO1995034545A1 (en) 1995-12-21
FI964936A0 (fi) 1996-12-10
EP0764157A1 (en) 1997-03-26
EP1114821A1 (en) 2001-07-11
SK281456B6 (sk) 2001-03-12
CZ361796A3 (en) 1997-08-13
SI1114821T1 (en) 2004-02-29
NO965260L (no) 1997-02-06
AP9600889A0 (en) 1997-01-31
JP2003238554A (ja) 2003-08-27
ATE211469T1 (de) 2002-01-15
JP3575767B2 (ja) 2004-10-13
AP714A (en) 1998-12-23
CZ286081B6 (cs) 2000-01-12
SI0764157T1 (en) 2002-06-30
KR100397721B1 (ko) 2004-04-28
DK1114821T3 (da) 2004-02-02
AU2672795A (en) 1996-01-05
HK1001286A1 (en) 1998-06-12
CY2508B1 (en) 2005-12-23
BG101040A (en) 1997-08-29
ATE250052T1 (de) 2003-10-15
CN1174975C (zh) 2004-11-10
US5760074A (en) 1998-06-02
RO113463B1 (ro) 1998-07-30
CA2192480C (en) 2007-07-24
NO315651B1 (no) 2003-10-06
ES2170798T3 (es) 2002-08-16
PL188134B1 (pl) 2004-12-31
HK1039115A1 (en) 2002-04-12
DE69531801D1 (de) 2003-10-23
CN1234702C (zh) 2006-01-04
DE69524871D1 (de) 2002-02-07
PT1114821E (pt) 2004-02-27
ES2207590T3 (es) 2004-06-01
DE69524871T2 (de) 2002-08-22
CN1336369A (zh) 2002-02-20
EP0764157B1 (en) 2002-01-02
CA2192480A1 (en) 1995-12-21
BG63339B1 (bg) 2001-10-31
FI964936A (fi) 1997-02-06
EP1114821B1 (en) 2003-09-17
CN1154698A (zh) 1997-07-16
SK158796A3 (en) 1997-07-09
OA10593A (en) 2002-07-10
PL317579A1 (en) 1997-04-14
DE69531801T2 (de) 2004-07-01
NO965260D0 (no) 1996-12-09
AU701060B2 (en) 1999-01-21
HU9603415D0 (en) 1997-02-28

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