DK0754682T3 - Aminostilbazolderivat og lægemiddel - Google Patents
Aminostilbazolderivat og lægemiddelInfo
- Publication number
- DK0754682T3 DK0754682T3 DK95914513T DK95914513T DK0754682T3 DK 0754682 T3 DK0754682 T3 DK 0754682T3 DK 95914513 T DK95914513 T DK 95914513T DK 95914513 T DK95914513 T DK 95914513T DK 0754682 T3 DK0754682 T3 DK 0754682T3
- Authority
- DK
- Denmark
- Prior art keywords
- represents hydrogen
- drug
- hydroxy
- ring
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6825294 | 1994-04-06 | ||
| PCT/JP1995/000658 WO1995027699A1 (fr) | 1994-04-06 | 1995-04-05 | Derive d'aminostilbazole et medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0754682T3 true DK0754682T3 (da) | 2002-02-04 |
Family
ID=13368389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95914513T DK0754682T3 (da) | 1994-04-06 | 1995-04-05 | Aminostilbazolderivat og lægemiddel |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5972976A (zh) |
| EP (1) | EP0754682B9 (zh) |
| JP (1) | JP3080405B2 (zh) |
| KR (1) | KR100293867B1 (zh) |
| CN (1) | CN1053658C (zh) |
| AT (1) | ATE207057T1 (zh) |
| CA (1) | CA2187214C (zh) |
| DE (1) | DE69523298T2 (zh) |
| DK (1) | DK0754682T3 (zh) |
| ES (1) | ES2165911T3 (zh) |
| PT (1) | PT754682E (zh) |
| RU (1) | RU2138482C1 (zh) |
| TW (1) | TW308586B (zh) |
| WO (1) | WO1995027699A1 (zh) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69824895T2 (de) * | 1998-04-15 | 2005-06-30 | Hidaka, Hiroyoshi, Nagoya | Verfahren zur bestimmung des gens eines zielproteins mit hilfe eines medikamentes |
| EP2316467A1 (en) * | 1998-05-12 | 2011-05-04 | GHC Research Development Corporation | Use of a prolactin variant for treating cancer |
| WO2000064875A1 (fr) * | 1999-04-23 | 2000-11-02 | Nippon Shinyaku Co., Ltd. | Procede de pulverisation |
| US6521658B1 (en) | 1999-05-28 | 2003-02-18 | Abbott Laboratories | Cell proliferation inhibitors |
| KR20020060998A (ko) * | 1999-12-14 | 2002-07-19 | 니뽄 신야쿠 가부시키가이샤 | 복소환 유도체 및 의약 |
| JP2004359545A (ja) * | 2001-03-08 | 2004-12-24 | D Western Therapeutics Institute | 抗癌剤耐性克服剤 |
| JP4228700B2 (ja) * | 2001-04-10 | 2009-02-25 | 日本新薬株式会社 | 慢性関節リウマチの治療剤 |
| US7148244B2 (en) | 2001-04-26 | 2006-12-12 | Nippon Shinyaku Co. Ltd. | Medicines in controlling Vpr function |
| US6951875B2 (en) * | 2001-10-29 | 2005-10-04 | Hoffmann-La Roche Inc. | Conjugated aromatic compounds with a pyridine substituent |
| FR2838437B1 (fr) * | 2002-04-11 | 2004-06-04 | Aventis Pharma Sa | Procedes de preparation de combretastatines |
| US20060128762A1 (en) * | 2002-09-06 | 2006-06-15 | D.Western Therapeutics Institute | Medicinal composition and method for treating malignant tumor and utilization thereof |
| WO2006078941A2 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Novel sirtuin activating compounds and methods of use thereof |
| WO2007137196A2 (en) * | 2006-05-19 | 2007-11-29 | Threshold Pharmaceuticals, Inc. | Tubulin binding anti cancer compounds and prodrugs thereof |
| US20100198262A1 (en) * | 2009-01-30 | 2010-08-05 | Mckinley Laurence M | Axial offset bone fastener system |
| MX2015014470A (es) | 2013-04-19 | 2016-02-22 | Univ Arkansas | Analogos de combretastatina. |
| US10640431B2 (en) | 2013-12-13 | 2020-05-05 | Eurochem Agro Gmbh | Fertilizer mixture containing nitrification inhibitor |
| WO2015153635A1 (en) | 2014-03-31 | 2015-10-08 | Board Of Trustees Of The University Of Arkansas | Disubstituted triazole analogs |
| DE102017201608A1 (de) | 2017-02-01 | 2018-08-02 | Eurochem Agro Gmbh | 3,4-Dimethylpyrazol enthaltende Mischung und ihre Verwendung |
| CN112110829B (zh) * | 2019-06-19 | 2023-08-01 | 复旦大学 | 一种能结合α-突触核蛋白聚集体的小分子化合物、其制备方法及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69129611T2 (de) * | 1990-08-20 | 1998-12-17 | Eisai Co., Ltd., Tokio/Tokyo | Sulfonamid-Derivate |
| JP2790926B2 (ja) * | 1990-08-20 | 1998-08-27 | エーザイ株式会社 | スルホンアミド誘導体 |
| JP2692467B2 (ja) * | 1991-12-09 | 1997-12-17 | ダイキン工業株式会社 | 空調制御装置の電力供給装置 |
| JP3342485B2 (ja) * | 1991-12-10 | 2002-11-11 | 塩野義製薬株式会社 | 芳香族スルホンアミド系ヒドロキサム酸誘導体 |
-
1995
- 1995-04-05 DK DK95914513T patent/DK0754682T3/da active
- 1995-04-05 ES ES95914513T patent/ES2165911T3/es not_active Expired - Lifetime
- 1995-04-05 KR KR1019960705560A patent/KR100293867B1/ko not_active IP Right Cessation
- 1995-04-05 PT PT95914513T patent/PT754682E/pt unknown
- 1995-04-05 WO PCT/JP1995/000658 patent/WO1995027699A1/ja active IP Right Grant
- 1995-04-05 CA CA002187214A patent/CA2187214C/en not_active Expired - Lifetime
- 1995-04-05 US US08/765,131 patent/US5972976A/en not_active Expired - Lifetime
- 1995-04-05 RU RU96121800A patent/RU2138482C1/ru active
- 1995-04-05 CN CN95192423A patent/CN1053658C/zh not_active Expired - Lifetime
- 1995-04-05 EP EP95914513A patent/EP0754682B9/en not_active Expired - Lifetime
- 1995-04-05 AT AT95914513T patent/ATE207057T1/de active
- 1995-04-05 DE DE69523298T patent/DE69523298T2/de not_active Expired - Lifetime
- 1995-04-05 JP JP07526235A patent/JP3080405B2/ja not_active Expired - Lifetime
- 1995-04-28 TW TW084104225A patent/TW308586B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0754682A1 (en) | 1997-01-22 |
| JP3080405B2 (ja) | 2000-08-28 |
| CN1145066A (zh) | 1997-03-12 |
| PT754682E (pt) | 2002-03-28 |
| ATE207057T1 (de) | 2001-11-15 |
| MX9604540A (es) | 1997-09-30 |
| TW308586B (zh) | 1997-06-21 |
| ES2165911T3 (es) | 2002-04-01 |
| CA2187214A1 (en) | 1995-10-19 |
| CA2187214C (en) | 2002-03-12 |
| KR970702253A (ko) | 1997-05-13 |
| CN1053658C (zh) | 2000-06-21 |
| US5972976A (en) | 1999-10-26 |
| DE69523298D1 (de) | 2001-11-22 |
| EP0754682A4 (en) | 1998-03-04 |
| KR100293867B1 (ko) | 2001-09-17 |
| RU2138482C1 (ru) | 1999-09-27 |
| EP0754682B9 (en) | 2003-09-17 |
| EP0754682B1 (en) | 2001-10-17 |
| WO1995027699A1 (fr) | 1995-10-19 |
| DE69523298T2 (de) | 2002-06-27 |
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