DK0733614T3 - Reagens og fremgangsmåde til at knytte en substitueret difluormethylgruppe til en forbindelse, der har mindst en elektrofil funktion - Google Patents

Reagens og fremgangsmåde til at knytte en substitueret difluormethylgruppe til en forbindelse, der har mindst en elektrofil funktion

Info

Publication number
DK0733614T3
DK0733614T3 DK96400625T DK96400625T DK0733614T3 DK 0733614 T3 DK0733614 T3 DK 0733614T3 DK 96400625 T DK96400625 T DK 96400625T DK 96400625 T DK96400625 T DK 96400625T DK 0733614 T3 DK0733614 T3 DK 0733614T3
Authority
DK
Denmark
Prior art keywords
electrophilic
reagent
linking
compound
difluoromethyl group
Prior art date
Application number
DK96400625T
Other languages
Danish (da)
English (en)
Inventor
Gerard Forat
Jean-Manuel Mas
Laurent Saint-Jalmes
Original Assignee
Rhodia Chimie Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26231834&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0733614(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9503512A external-priority patent/FR2732010B1/fr
Priority claimed from FR9515763A external-priority patent/FR2743065B1/fr
Application filed by Rhodia Chimie Sa filed Critical Rhodia Chimie Sa
Application granted granted Critical
Publication of DK0733614T3 publication Critical patent/DK0733614T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C19/00—Acyclic saturated compounds containing halogen atoms
    • C07C19/08—Acyclic saturated compounds containing halogen atoms containing fluorine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
DK96400625T 1995-03-24 1996-03-22 Reagens og fremgangsmåde til at knytte en substitueret difluormethylgruppe til en forbindelse, der har mindst en elektrofil funktion DK0733614T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9503512A FR2732010B1 (fr) 1995-03-24 1995-03-24 Reactif et procede utiles pour greffer un groupement difluoromethyle substitue sur un compose comportant au moins une fonction electrophile
FR9515763A FR2743065B1 (fr) 1995-12-29 1995-12-29 Reactif et procede utiles pour greffer un groupement difluoromethyle substitue sur un compose comportant au moins une fonction electrophile

Publications (1)

Publication Number Publication Date
DK0733614T3 true DK0733614T3 (da) 2001-09-10

Family

ID=26231834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96400625T DK0733614T3 (da) 1995-03-24 1996-03-22 Reagens og fremgangsmåde til at knytte en substitueret difluormethylgruppe til en forbindelse, der har mindst en elektrofil funktion

Country Status (22)

Country Link
US (1) US5756849A (tr)
EP (1) EP0733614B2 (tr)
JP (1) JP4450875B2 (tr)
KR (1) KR100436787B1 (tr)
CN (1) CN1150148C (tr)
AT (1) ATE201393T1 (tr)
AU (1) AU4822896A (tr)
BR (1) BR9601109A (tr)
CA (1) CA2172450A1 (tr)
CZ (1) CZ85596A3 (tr)
DE (1) DE69612899T3 (tr)
DK (1) DK0733614T3 (tr)
ES (1) ES2157407T5 (tr)
HU (1) HU217027B (tr)
IL (1) IL117534A0 (tr)
PL (1) PL313435A1 (tr)
PT (1) PT733614E (tr)
RO (1) RO117911B1 (tr)
RU (1) RU2204545C2 (tr)
SK (1) SK37096A3 (tr)
TR (1) TR199600234A1 (tr)
UA (1) UA45324C2 (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19824488A1 (de) * 1998-06-02 1999-12-09 Bayer Ag Verfahren zur Herstellung von Perfluoralkyl-aryl-sulfiden und neue Perfluoralkyl-aryl-sulfide
AU2002236830A1 (en) 2001-01-26 2002-08-06 Chugai Seiyaku Kabushiki Kaisha Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors
WO2002064136A2 (en) 2001-01-26 2002-08-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
AU2002245294B2 (en) 2001-01-26 2005-09-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
DK1370260T3 (da) 2001-02-20 2011-03-14 Chugai Pharmaceutical Co Ltd Azoler, som malonyl-coa-decarboxylaseinhibitorer anvendelige som mataboliske modulatorer
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
FR2827285B1 (fr) * 2001-07-10 2003-12-05 Rhodia Chimie Sa Reactif et procede pour la perfluoroalcoylation
US6803477B2 (en) 2001-11-29 2004-10-12 University Of Southern California Magnesium mediated preparation of fluorinated alkyl silanes
EP1653957B1 (en) 2003-08-01 2008-07-09 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-coa decarboxylase inhibitors
US7285562B2 (en) 2003-08-01 2007-10-23 Chugai Seiyaku Kabushiki Kaisha Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
US7786145B2 (en) 2003-08-01 2010-08-31 Chugai Seiyaku Kabushiki Kaisha Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
ES2353306T3 (es) 2003-08-01 2011-03-01 Chugai Seiyaku Kabushiki Kaisha Compuestos heterocíclicos útiles como inhibidores de la malonil-coa-descarboxilasa.
US7710197B2 (en) * 2007-07-11 2010-05-04 Axiom Microdevices, Inc. Low offset envelope detector and method of use
US11028105B2 (en) 2018-06-29 2021-06-08 The Regents Of The University Of Michigan Difluoromethyl and difluoromethylene transfer reagents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822904A (en) * 1985-12-12 1989-04-18 Ethyl Corporation Perfluoroalkylation process
US4808748A (en) * 1985-12-12 1989-02-28 Ethyl Corporation Trifluoromethylation process
US4990699A (en) * 1988-10-17 1991-02-05 Ethyl Corporation Perfluoroalkylation process

Also Published As

Publication number Publication date
KR960034146A (ko) 1996-10-22
CN1137508A (zh) 1996-12-11
RU2204545C2 (ru) 2003-05-20
KR100436787B1 (ko) 2004-09-18
PL313435A1 (en) 1996-09-30
MX9601075A (es) 1997-07-31
DE69612899D1 (de) 2001-06-28
EP0733614B2 (fr) 2010-01-13
HU217027B (hu) 1999-11-29
EP0733614B1 (fr) 2001-05-23
ATE201393T1 (de) 2001-06-15
AU4822896A (en) 1996-10-03
TR199600234A1 (tr) 1997-03-21
JPH08319251A (ja) 1996-12-03
ES2157407T3 (es) 2001-08-16
DE69612899T3 (de) 2010-06-10
CN1150148C (zh) 2004-05-19
HUP9600724A1 (en) 1997-04-28
UA45324C2 (uk) 2002-04-15
BR9601109A (pt) 1998-01-06
EP0733614A1 (fr) 1996-09-25
HU9600724D0 (en) 1996-05-28
PT733614E (pt) 2001-08-30
CZ85596A3 (en) 1996-10-16
DE69612899T2 (de) 2001-10-11
IL117534A0 (en) 1996-07-23
RO117911B1 (ro) 2002-09-30
JP4450875B2 (ja) 2010-04-14
ES2157407T5 (es) 2010-04-20
US5756849A (en) 1998-05-26
CA2172450A1 (fr) 1996-09-25
SK37096A3 (en) 1997-07-09

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