ATE66471T1 - Verfahren zur herstellung von retinoylchloriden. - Google Patents
Verfahren zur herstellung von retinoylchloriden.Info
- Publication number
- ATE66471T1 ATE66471T1 AT87308333T AT87308333T ATE66471T1 AT E66471 T1 ATE66471 T1 AT E66471T1 AT 87308333 T AT87308333 T AT 87308333T AT 87308333 T AT87308333 T AT 87308333T AT E66471 T1 ATE66471 T1 AT E66471T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- retinoyl
- chlorides
- retinoyl chlorides
- chem
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- XAEXWGDKGUEINI-UHFFFAOYSA-N n,n-dimethylcarbamimidoyl chloride;hydrochloride Chemical compound [Cl-].C[N+](C)=C(N)Cl XAEXWGDKGUEINI-UHFFFAOYSA-N 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- -1 retinoyl chlorides Chemical class 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/909,794 US4743400A (en) | 1986-09-22 | 1986-09-22 | Process for preparing retinoyl chlorides |
| EP87308333A EP0261911B1 (de) | 1986-09-22 | 1987-09-21 | Verfahren zur Herstellung von Retinoylchloriden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE66471T1 true ATE66471T1 (de) | 1991-09-15 |
Family
ID=25427847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87308333T ATE66471T1 (de) | 1986-09-22 | 1987-09-21 | Verfahren zur herstellung von retinoylchloriden. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4743400A (de) |
| EP (1) | EP0261911B1 (de) |
| JP (1) | JPH07107044B2 (de) |
| AT (1) | ATE66471T1 (de) |
| CA (1) | CA1278310C (de) |
| DE (1) | DE3772308D1 (de) |
| ES (1) | ES2024515B3 (de) |
| GR (1) | GR3002588T3 (de) |
| HK (1) | HK2092A (de) |
| HU (1) | HU201523B (de) |
| IE (1) | IE62102B1 (de) |
| SG (1) | SG96791G (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5057502A (en) * | 1987-06-02 | 1991-10-15 | Walsh William E | Composition and topical and systemic treatments of conditions caused by heavy, oily or greasy secretions |
| US5399757A (en) * | 1993-07-20 | 1995-03-21 | Ortho Pharmaceutical Corporation | Process for the preparation of N-(4-hydroxyphenyl)-retinamide |
| DE60234024D1 (de) * | 2001-05-29 | 2009-11-26 | Chebigen Co Ltd | Neue retinoidderivate und eine pharmazeutische anti-krebs-zusammensetzung, die diese verbindungen enthält |
| JP2005020400A (ja) * | 2003-06-26 | 2005-01-20 | Hitachi Communication Technologies Ltd | 無線基地局、無線通信システム、無線基地局の通信制御方法、および、無線通信網の構築方法 |
| US20080176952A1 (en) * | 2004-02-17 | 2008-07-24 | Rando Robert R | Management of Ophthalmologic Disorders, Including Macular Degeneration |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| SG140607A1 (en) | 2004-06-23 | 2008-03-28 | Sirion Therapeutics Inc | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
| US7432307B2 (en) * | 2004-11-04 | 2008-10-07 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation |
| CA2584845C (en) | 2004-12-08 | 2009-02-17 | Sirion Therapeutics, Inc. | Methods, assays and compositions for treating retinol-related diseases |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| KR101875394B1 (ko) * | 2015-12-07 | 2018-07-06 | 엔프라니 주식회사 | 도파민을 함유하는 레티노이드 화합물 및 그의 제조방법 |
| CN114436924B (zh) * | 2022-02-21 | 2023-09-29 | 青岛三人行化学有限公司 | 一种羟基频哪酮视黄酸酯的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2300107C2 (de) * | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
| DE2306112A1 (de) * | 1973-02-08 | 1974-08-15 | Basf Ag | Thioharnstoffderivate der vitamin-asaeure |
| DE2456959A1 (de) * | 1974-12-03 | 1976-06-16 | Basf Ag | 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen |
| US4055659A (en) * | 1975-11-03 | 1977-10-25 | Johnson & Johnson | Retinoic acid derivatives |
| US4190594A (en) * | 1975-11-03 | 1980-02-26 | Johnson & Johnson | Retinoic acid derivatives |
| US4108880A (en) * | 1975-11-03 | 1978-08-22 | Johnson & Johnson | Esters of retinoic acid |
| US4323581A (en) * | 1978-07-31 | 1982-04-06 | Johnson & Johnson | Method of treating carcinogenesis |
| DE2843870A1 (de) * | 1978-10-07 | 1980-04-24 | Basf Ag | N-hydroxypropylamide der all-e- und 13-z-retinsaeure |
-
1986
- 1986-09-22 US US06/909,794 patent/US4743400A/en not_active Expired - Lifetime
-
1987
- 1987-09-21 JP JP62235043A patent/JPH07107044B2/ja not_active Expired - Lifetime
- 1987-09-21 IE IE254287A patent/IE62102B1/en not_active IP Right Cessation
- 1987-09-21 DE DE8787308333T patent/DE3772308D1/de not_active Expired - Lifetime
- 1987-09-21 EP EP87308333A patent/EP0261911B1/de not_active Expired - Lifetime
- 1987-09-21 AT AT87308333T patent/ATE66471T1/de not_active IP Right Cessation
- 1987-09-21 CA CA000547388A patent/CA1278310C/en not_active Expired - Lifetime
- 1987-09-21 HU HU874254A patent/HU201523B/hu unknown
- 1987-09-21 ES ES87308333T patent/ES2024515B3/es not_active Expired - Lifetime
-
1991
- 1991-08-22 GR GR91401162T patent/GR3002588T3/el unknown
- 1991-11-15 SG SG967/91A patent/SG96791G/en unknown
-
1992
- 1992-01-02 HK HK20/92A patent/HK2092A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07107044B2 (ja) | 1995-11-15 |
| GR3002588T3 (en) | 1993-01-25 |
| US4743400A (en) | 1988-05-10 |
| EP0261911A2 (de) | 1988-03-30 |
| ES2024515B3 (es) | 1992-03-01 |
| EP0261911A3 (en) | 1988-06-01 |
| IE62102B1 (en) | 1994-12-14 |
| SG96791G (en) | 1992-01-17 |
| HK2092A (en) | 1992-01-10 |
| DE3772308D1 (de) | 1991-09-26 |
| HU201523B (en) | 1990-11-28 |
| HUT45009A (en) | 1988-05-30 |
| CA1278310C (en) | 1990-12-27 |
| IE872542L (en) | 1988-03-22 |
| EP0261911B1 (de) | 1991-08-21 |
| JPS63119456A (ja) | 1988-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |