DK0675717T3 - Anvendelse af 2-amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) som lægemiddel med antidepressiv virknin - Google Patents

Anvendelse af 2-amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) som lægemiddel med antidepressiv virknin

Info

Publication number
DK0675717T3
DK0675717T3 DK94902661T DK94902661T DK0675717T3 DK 0675717 T3 DK0675717 T3 DK 0675717T3 DK 94902661 T DK94902661 T DK 94902661T DK 94902661 T DK94902661 T DK 94902661T DK 0675717 T3 DK0675717 T3 DK 0675717T3
Authority
DK
Denmark
Prior art keywords
tetrahydrobenzothiazole
pramipexole
propylamino
drug
amino
Prior art date
Application number
DK94902661T
Other languages
Danish (da)
English (en)
Inventor
Rudolf Hammer
Joachim Mierau
Erich Lehr
Franco Borsini
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK0675717T3 publication Critical patent/DK0675717T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK94902661T 1992-12-05 1993-12-02 Anvendelse af 2-amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) som lægemiddel med antidepressiv virknin DK0675717T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241013A DE4241013A1 (de) 1992-12-05 1992-12-05 Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
PCT/EP1993/003389 WO1994013287A1 (de) 1992-12-05 1993-12-02 Verwendung von 2-amino-6-a-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) als arzneimittel mit antidepressiver wirkung

Publications (1)

Publication Number Publication Date
DK0675717T3 true DK0675717T3 (da) 2000-02-28

Family

ID=6474503

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94902661T DK0675717T3 (da) 1992-12-05 1993-12-02 Anvendelse af 2-amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) som lægemiddel med antidepressiv virknin

Country Status (28)

Country Link
US (1) US6191153B1 (cs)
EP (1) EP0675717B1 (cs)
JP (1) JP3221880B2 (cs)
KR (1) KR100311165B1 (cs)
CN (1) CN1052400C (cs)
AT (1) ATE183091T1 (cs)
AU (1) AU674378B2 (cs)
BG (1) BG62475B1 (cs)
CA (1) CA2150131C (cs)
CZ (1) CZ282679B6 (cs)
DE (2) DE4241013A1 (cs)
DK (1) DK0675717T3 (cs)
ES (1) ES2136725T3 (cs)
FI (1) FI952734A0 (cs)
GR (1) GR3031521T3 (cs)
HU (1) HU221014B1 (cs)
IL (1) IL107870A (cs)
MX (1) MX9307644A (cs)
NO (1) NO306930B1 (cs)
NZ (1) NZ258876A (cs)
PL (1) PL309282A1 (cs)
RU (1) RU2157685C2 (cs)
SG (1) SG49228A1 (cs)
SK (1) SK281441B6 (cs)
TW (1) TW362973B (cs)
UA (1) UA35604C2 (cs)
WO (1) WO1994013287A1 (cs)
ZA (1) ZA939065B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650420A (en) * 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
US6156777A (en) 1994-12-15 2000-12-05 Pharmacia & Upjohn Company Use of pramipexole as a neuroprotective agent
US6001861A (en) 1998-01-16 1999-12-14 Pharmacia & Upjohn Company Use of pramipexole in the treatment of restless legs syndrome
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
WO2000006162A1 (de) * 1998-07-27 2000-02-10 Boehringer Ingelheim Pharma Kg Mittel mit antidepressiver wirkung, mit pramipexol und einem weiteren antidepressivum
PE20011074A1 (es) 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
CA2415815A1 (en) * 2000-07-06 2002-01-17 Nigel H. Greig Tetrahydrobenzothiazole analogues as neuroprotective agents
US20020165246A1 (en) * 2001-03-05 2002-11-07 Andrew Holman Administration of sleep restorative agents
EP1260221A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
US6727247B2 (en) * 2001-12-10 2004-04-27 Hoffman-La Roche Inc. Substituted benzothiazole amide derivatives
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
GB2394951A (en) * 2002-11-04 2004-05-12 Cipla Ltd One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole
DE102004006808A1 (de) 2004-02-11 2005-09-01 Grünenthal GmbH Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen
ES2355735T5 (es) * 2004-08-13 2014-06-27 Boehringer Ingelheim International Gmbh Formulación en comprimidos de liberación extendida que contiene pramipexol o una de sus sales farmac�uticamente aceptables, método para su fabricación y su uso
EP2431026A1 (en) * 2004-08-13 2012-03-21 Boehringer Ingelheim International GmbH Extended release pellet formulation containing Pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
US20090042861A1 (en) * 2005-04-04 2009-02-12 Takeda Pharmaceutical Company Limited Prophylactic or Therapeutic Agent for Depression or Anxiety Disorder
US20080262053A1 (en) * 2005-10-18 2008-10-23 Juergen Reess Use of Pramipexole for Treating Moderate to Severe Restless Legs Syndrome (Rls)
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
EP1988875A2 (en) * 2006-02-10 2008-11-12 Boehringer Ingelheim International GmbH Modified release formulation
IL312486B2 (en) * 2017-04-10 2025-05-01 Chase Therapeutics Corp NK1 antagonist combination and method for treating synucleinopathies
ES3009607T3 (en) 2017-06-30 2025-03-27 Chase Therapeutics Corp Nk-1 antagonist compositions and methods for use in treating depression
TWI672472B (zh) * 2018-08-15 2019-09-21 鄭映芳 飲料製冰機裝置
CN110028464B (zh) * 2019-04-26 2022-11-18 浙江海洋大学 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186087B1 (de) * 1984-12-22 1989-08-23 Dr. Karl Thomae GmbH Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel
DE3843227A1 (de) * 1988-12-22 1990-07-05 Boehringer Ingelheim Kg Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol
DE3930282A1 (de) * 1989-09-11 1991-03-21 Boehringer Ingelheim Kg Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit

Also Published As

Publication number Publication date
DE59309733D1 (de) 1999-09-16
SG49228A1 (en) 1998-05-18
JP3221880B2 (ja) 2001-10-22
KR950703953A (ko) 1995-11-17
EP0675717A1 (de) 1995-10-11
HUT71798A (en) 1996-02-28
RU2157685C2 (ru) 2000-10-20
CN1091635A (zh) 1994-09-07
FI952734L (fi) 1995-06-05
IL107870A0 (en) 1994-04-12
ZA939065B (en) 1994-08-04
US6191153B1 (en) 2001-02-20
WO1994013287A1 (de) 1994-06-23
NO306930B1 (no) 2000-01-17
NO952207D0 (no) 1995-06-02
CZ282679B6 (cs) 1997-08-13
EP0675717B1 (de) 1999-08-11
CA2150131C (en) 2004-09-21
BG99700A (bg) 1996-04-30
CZ144095A3 (en) 1996-03-13
HU221014B1 (hu) 2002-07-29
UA35604C2 (uk) 2001-04-16
DE4241013A1 (de) 1994-06-09
MX9307644A (es) 1994-06-30
FI952734A7 (fi) 1995-06-05
ATE183091T1 (de) 1999-08-15
GR3031521T3 (en) 2000-01-31
PL309282A1 (en) 1995-10-02
NZ258876A (en) 1997-07-27
SK74095A3 (en) 1996-05-08
JPH08504201A (ja) 1996-05-07
CA2150131A1 (en) 1994-06-23
HK1019003A1 (en) 2000-01-14
HU9501623D0 (en) 1995-08-28
AU674378B2 (en) 1996-12-19
TW362973B (en) 1999-07-01
ES2136725T3 (es) 1999-12-01
KR100311165B1 (ko) 2001-12-28
SK281441B6 (sk) 2001-03-12
NO952207L (no) 1995-06-02
AU5715294A (en) 1994-07-04
IL107870A (en) 1996-12-05
CN1052400C (zh) 2000-05-17
BG62475B1 (bg) 1999-12-30
FI952734A0 (fi) 1995-06-05

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