DK0656211T3 - Stabilt lyofiliseret thiotepa-præparat - Google Patents

Stabilt lyofiliseret thiotepa-præparat

Info

Publication number
DK0656211T3
DK0656211T3 DK94117666T DK94117666T DK0656211T3 DK 0656211 T3 DK0656211 T3 DK 0656211T3 DK 94117666 T DK94117666 T DK 94117666T DK 94117666 T DK94117666 T DK 94117666T DK 0656211 T3 DK0656211 T3 DK 0656211T3
Authority
DK
Denmark
Prior art keywords
stably
preparation
thiotepa
lyophilized
lyophilized thiotepa
Prior art date
Application number
DK94117666T
Other languages
Danish (da)
English (en)
Inventor
Mannching S Ku
Jorge Velez
Joe Hoffman
Lourdes Zamora
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0656211T3 publication Critical patent/DK0656211T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94117666T 1993-11-09 1994-11-09 Stabilt lyofiliseret thiotepa-præparat DK0656211T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15050193A 1993-11-09 1993-11-09

Publications (1)

Publication Number Publication Date
DK0656211T3 true DK0656211T3 (da) 1999-11-15

Family

ID=22534834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94117666T DK0656211T3 (da) 1993-11-09 1994-11-09 Stabilt lyofiliseret thiotepa-præparat

Country Status (29)

Country Link
US (1) US5561121A (fr)
EP (1) EP0656211B1 (fr)
JP (1) JP3726255B2 (fr)
KR (1) KR100348382B1 (fr)
CN (1) CN1111130A (fr)
AR (1) AR023045A2 (fr)
AT (1) ATE180670T1 (fr)
AU (1) AU690143B2 (fr)
CA (1) CA2135265A1 (fr)
CZ (1) CZ287052B6 (fr)
DE (1) DE69418832T2 (fr)
DK (1) DK0656211T3 (fr)
ES (1) ES2133152T3 (fr)
FI (1) FI116036B (fr)
GR (1) GR3031122T3 (fr)
HK (1) HK1011283A1 (fr)
HU (1) HU218216B (fr)
IL (1) IL111534A (fr)
NO (1) NO305274B1 (fr)
NZ (1) NZ264861A (fr)
PE (1) PE22995A1 (fr)
PH (1) PH31219A (fr)
PL (1) PL176984B1 (fr)
RU (1) RU2134112C1 (fr)
SG (1) SG63584A1 (fr)
SI (1) SI0656211T1 (fr)
SK (1) SK280840B6 (fr)
TW (1) TW344662B (fr)
ZA (1) ZA948833B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726343D0 (en) * 1997-12-13 1998-02-11 Auffret Anthony The use of excipients to accelerate freeze-drying
AU2002302814A1 (en) * 2001-06-08 2002-12-23 Powderject Vaccines, Inc. Spray freeze-dried compositions
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
WO2010036702A1 (fr) 2008-09-25 2010-04-01 Cephalon, Inc. Formulations liquides de bendamustine
JP2012515210A (ja) 2009-01-15 2012-07-05 セファロン、インク. ベンダムスチン遊離塩基の新規の形態
CA2850513A1 (fr) * 2011-09-29 2013-04-04 Janssen Pharmaceutica Nv Procede de preparation de derives de sulfamides
CN104349417B (zh) * 2013-08-07 2017-11-21 中国科学院声学研究所 基于短生命周期的区域性水下通信网的组网方法
WO2018227112A1 (fr) 2017-06-09 2018-12-13 The Trustees Of Columbia University In The City Of New York Oligomères tat courts pour l'administration de médicaments
CN109956972A (zh) * 2017-12-22 2019-07-02 四川科瑞德凯华制药有限公司 塞替派晶型i及其制备方法和用途
CN110917146A (zh) * 2019-12-03 2020-03-27 黑龙江福和制药集团股份有限公司 一种塞替派粉针及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2670347A (en) * 1952-01-08 1954-02-23 American Cyanamid Co Thiophosphoric acid derivatives and method of preparing the same
GB845823A (en) * 1957-09-19 1960-08-24 Sumitomo Chemical Co Stabilised compositions comprising therapeutic imine derivatives and the preparation thereof
DE1951822C3 (de) * 1969-10-14 1980-12-11 Kowa Co., Ltd., Nagoya, Aichi (Japan) Pharmazeutisches Präparat zur Krebsbehandlung
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
EP0120907A1 (fr) * 1982-10-13 1984-10-10 Aston Molecules Limited Preparations pharmaceutiques utilisees en therapie antitumorale
EP0140255B1 (fr) * 1983-10-14 1991-05-15 Sumitomo Pharmaceuticals Company, Limited Injections à libération prolongée
CH676508A5 (fr) * 1986-10-13 1991-01-31 Anawa Lab Ag
US4918199A (en) * 1988-01-21 1990-04-17 American Cyanamid Company Process for producing thiotepa
US5122367A (en) * 1989-03-31 1992-06-16 Massachusetts Institute Of Technology Polyanhydride bioerodible controlled release implants for administration of stabilized growth hormone
EP0419890A3 (en) * 1989-09-29 1991-05-29 American Cyanamid Company Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method

Also Published As

Publication number Publication date
JP3726255B2 (ja) 2005-12-14
KR100348382B1 (ko) 2002-11-23
CA2135265A1 (fr) 1995-05-10
CZ287052B6 (en) 2000-08-16
JPH07196517A (ja) 1995-08-01
PH31219A (en) 1998-05-05
EP0656211B1 (fr) 1999-06-02
PE22995A1 (es) 1995-09-08
NO944256D0 (no) 1994-11-08
SK280840B6 (sk) 2000-08-14
DE69418832D1 (de) 1999-07-08
IL111534A0 (en) 1995-01-24
RU94040150A (ru) 1996-09-20
TW344662B (en) 1998-11-11
FI116036B (fi) 2005-09-15
CN1111130A (zh) 1995-11-08
PL176984B1 (pl) 1999-08-31
HUT70762A (en) 1995-10-30
FI945252A0 (fi) 1994-11-08
SK135294A3 (en) 1996-01-10
SG63584A1 (en) 1999-03-30
CZ271894A3 (en) 1995-07-12
IL111534A (en) 1999-06-20
FI945252A (fi) 1995-05-10
ATE180670T1 (de) 1999-06-15
AR023045A2 (es) 2002-09-04
AU7768994A (en) 1995-05-18
GR3031122T3 (en) 1999-12-31
PL305752A1 (en) 1995-05-15
SI0656211T1 (en) 1999-08-31
NO305274B1 (no) 1999-05-03
AU690143B2 (en) 1998-04-23
RU2134112C1 (ru) 1999-08-10
NZ264861A (en) 1995-10-26
HK1011283A1 (en) 1999-07-09
ES2133152T3 (es) 1999-09-01
EP0656211A1 (fr) 1995-06-07
ZA948833B (en) 1995-07-14
US5561121A (en) 1996-10-01
HU218216B (hu) 2000-06-28
NO944256L (no) 1995-05-10
DE69418832T2 (de) 1999-09-23
HU9403210D0 (en) 1995-01-30

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