SG63584A1 - Stable lyophilized thiotepa composition - Google Patents

Stable lyophilized thiotepa composition

Info

Publication number
SG63584A1
SG63584A1 SG1996003935A SG1996003935A SG63584A1 SG 63584 A1 SG63584 A1 SG 63584A1 SG 1996003935 A SG1996003935 A SG 1996003935A SG 1996003935 A SG1996003935 A SG 1996003935A SG 63584 A1 SG63584 A1 SG 63584A1
Authority
SG
Singapore
Prior art keywords
stable lyophilized
composition
thiotepa composition
lyophilized thiotepa
stable
Prior art date
Application number
SG1996003935A
Other languages
English (en)
Inventor
Lourdes Zamora
Joe Hoffman
Jorge Velez
Mannching S Lu
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SG63584A1 publication Critical patent/SG63584A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG1996003935A 1993-11-09 1994-11-09 Stable lyophilized thiotepa composition SG63584A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15050193A 1993-11-09 1993-11-09

Publications (1)

Publication Number Publication Date
SG63584A1 true SG63584A1 (en) 1999-03-30

Family

ID=22534834

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996003935A SG63584A1 (en) 1993-11-09 1994-11-09 Stable lyophilized thiotepa composition

Country Status (29)

Country Link
US (1) US5561121A (fr)
EP (1) EP0656211B1 (fr)
JP (1) JP3726255B2 (fr)
KR (1) KR100348382B1 (fr)
CN (1) CN1111130A (fr)
AR (1) AR023045A2 (fr)
AT (1) ATE180670T1 (fr)
AU (1) AU690143B2 (fr)
CA (1) CA2135265A1 (fr)
CZ (1) CZ287052B6 (fr)
DE (1) DE69418832T2 (fr)
DK (1) DK0656211T3 (fr)
ES (1) ES2133152T3 (fr)
FI (1) FI116036B (fr)
GR (1) GR3031122T3 (fr)
HK (1) HK1011283A1 (fr)
HU (1) HU218216B (fr)
IL (1) IL111534A (fr)
NO (1) NO305274B1 (fr)
NZ (1) NZ264861A (fr)
PE (1) PE22995A1 (fr)
PH (1) PH31219A (fr)
PL (1) PL176984B1 (fr)
RU (1) RU2134112C1 (fr)
SG (1) SG63584A1 (fr)
SI (1) SI0656211T1 (fr)
SK (1) SK280840B6 (fr)
TW (1) TW344662B (fr)
ZA (1) ZA948833B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726343D0 (en) * 1997-12-13 1998-02-11 Auffret Anthony The use of excipients to accelerate freeze-drying
JP2004532277A (ja) * 2001-06-08 2004-10-21 パウダージェクト ワクチンズ,インコーポレーテッド 噴霧凍結乾燥組成物
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
CA2735899A1 (fr) 2008-09-25 2010-04-01 Cephalon, Inc. Formulations liquides de bendamustine
MX2011007557A (es) 2009-01-15 2011-08-12 Cephalon Inc Formas nuevas de bendamustina como base libre.
AU2012316279A1 (en) * 2011-09-29 2014-04-17 Janssen Pharmaceutica Nv Process for the preparation of sulfamide derivatives
CN104349417B (zh) * 2013-08-07 2017-11-21 中国科学院声学研究所 基于短生命周期的区域性水下通信网的组网方法
WO2018227112A1 (fr) * 2017-06-09 2018-12-13 The Trustees Of Columbia University In The City Of New York Oligomères tat courts pour l'administration de médicaments
CN109956972A (zh) * 2017-12-22 2019-07-02 四川科瑞德凯华制药有限公司 塞替派晶型i及其制备方法和用途
CN110917146A (zh) * 2019-12-03 2020-03-27 黑龙江福和制药集团股份有限公司 一种塞替派粉针及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2670347A (en) * 1952-01-08 1954-02-23 American Cyanamid Co Thiophosphoric acid derivatives and method of preparing the same
GB845823A (en) * 1957-09-19 1960-08-24 Sumitomo Chemical Co Stabilised compositions comprising therapeutic imine derivatives and the preparation thereof
DE1951822C3 (de) * 1969-10-14 1980-12-11 Kowa Co., Ltd., Nagoya, Aichi (Japan) Pharmazeutisches Präparat zur Krebsbehandlung
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
WO1984001506A1 (fr) * 1982-10-13 1984-04-26 Univ Birmingham Preparations pharmaceutiques utilisees en therapie antitumorale
DE3484584D1 (de) * 1983-10-14 1991-06-20 Sumitomo Pharma Injektionen mit verzoegerter abgabe.
CH676508A5 (fr) * 1986-10-13 1991-01-31 Anawa Lab Ag
US4918199A (en) * 1988-01-21 1990-04-17 American Cyanamid Company Process for producing thiotepa
US5122367A (en) * 1989-03-31 1992-06-16 Massachusetts Institute Of Technology Polyanhydride bioerodible controlled release implants for administration of stabilized growth hormone
EP0419890A3 (en) * 1989-09-29 1991-05-29 American Cyanamid Company Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method

Also Published As

Publication number Publication date
GR3031122T3 (en) 1999-12-31
SI0656211T1 (en) 1999-08-31
CZ287052B6 (en) 2000-08-16
JPH07196517A (ja) 1995-08-01
AR023045A2 (es) 2002-09-04
AU7768994A (en) 1995-05-18
CA2135265A1 (fr) 1995-05-10
NO305274B1 (no) 1999-05-03
TW344662B (en) 1998-11-11
EP0656211A1 (fr) 1995-06-07
RU94040150A (ru) 1996-09-20
NZ264861A (en) 1995-10-26
CN1111130A (zh) 1995-11-08
DE69418832D1 (de) 1999-07-08
DK0656211T3 (da) 1999-11-15
HU218216B (hu) 2000-06-28
FI945252A (fi) 1995-05-10
NO944256L (no) 1995-05-10
SK135294A3 (en) 1996-01-10
ZA948833B (en) 1995-07-14
IL111534A0 (en) 1995-01-24
HK1011283A1 (en) 1999-07-09
ATE180670T1 (de) 1999-06-15
SK280840B6 (sk) 2000-08-14
PH31219A (en) 1998-05-05
RU2134112C1 (ru) 1999-08-10
EP0656211B1 (fr) 1999-06-02
JP3726255B2 (ja) 2005-12-14
DE69418832T2 (de) 1999-09-23
PL176984B1 (pl) 1999-08-31
HUT70762A (en) 1995-10-30
IL111534A (en) 1999-06-20
ES2133152T3 (es) 1999-09-01
AU690143B2 (en) 1998-04-23
FI945252A0 (fi) 1994-11-08
NO944256D0 (no) 1994-11-08
FI116036B (fi) 2005-09-15
PL305752A1 (en) 1995-05-15
KR100348382B1 (ko) 2002-11-23
US5561121A (en) 1996-10-01
CZ271894A3 (en) 1995-07-12
HU9403210D0 (en) 1995-01-30
PE22995A1 (es) 1995-09-08

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