DK0646578T3 - Phenylcarboxamidisoxazoler og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmace - Google Patents

Phenylcarboxamidisoxazoler og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmace

Info

Publication number
DK0646578T3
DK0646578T3 DK94402183T DK94402183T DK0646578T3 DK 0646578 T3 DK0646578 T3 DK 0646578T3 DK 94402183 T DK94402183 T DK 94402183T DK 94402183 T DK94402183 T DK 94402183T DK 0646578 T3 DK0646578 T3 DK 0646578T3
Authority
DK
Denmark
Prior art keywords
group
carbon atoms
salts
preparation
ncx3
Prior art date
Application number
DK94402183T
Other languages
Danish (da)
English (en)
Inventor
Elizabeth Anne Kuo
Robert Westwood
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0646578T3 publication Critical patent/DK0646578T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94402183T 1993-10-01 1994-09-29 Phenylcarboxamidisoxazoler og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmace DK0646578T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939320299A GB9320299D0 (en) 1993-10-01 1993-10-01 Isoxazole derivatives

Publications (1)

Publication Number Publication Date
DK0646578T3 true DK0646578T3 (da) 2000-10-30

Family

ID=10742865

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94402183T DK0646578T3 (da) 1993-10-01 1994-09-29 Phenylcarboxamidisoxazoler og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmace

Country Status (11)

Country Link
US (2) US5476866A (es)
EP (1) EP0646578B1 (es)
JP (1) JP3723589B2 (es)
AT (1) ATE193531T1 (es)
CA (1) CA2133140C (es)
DE (1) DE69424734T2 (es)
DK (1) DK0646578T3 (es)
ES (1) ES2146643T3 (es)
GB (1) GB9320299D0 (es)
GR (1) GR3034023T3 (es)
PT (1) PT646578E (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721277A (en) * 1995-04-21 1998-02-24 Sugen, Inc. Compounds and methods for inhibiting hyper-proliferative cell growth
DE19539638A1 (de) * 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen
CA2302438A1 (en) * 1997-05-19 1998-11-26 Sugen, Inc. Heteroarylcarboxamide compounds active against protein tyrosine kinase related disorders
US6316479B1 (en) 1997-05-19 2001-11-13 Sugen, Inc. Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders
EP0987256B1 (de) 1997-08-08 2001-10-17 Aventis Pharma Deutschland GmbH Kristallform von N-(4-Trifluormethylphenyl)-5-methylisoxazol-4-carbonsäureamid
US6579880B2 (en) 2000-06-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
US20020048550A1 (en) * 2000-07-20 2002-04-25 Vallera Daniel A. Radiolabeled immunotoxins
MXPA04000224A (es) 2001-07-10 2005-07-25 4Sc Ag Novedosos compuestos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
KR20030063046A (ko) * 2002-01-22 2003-07-28 주식회사 엘지생명과학 엘비84068을 함유하는 염증으로 인한 질환의 예방 및치료용 조성물 및 이를 포함하는 제제
ES2368735T3 (es) 2002-12-23 2011-11-21 4Sc Ag Compuestos aromáticos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
UA108760C2 (uk) 2010-07-01 2015-06-10 Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби
MX2016006678A (es) 2013-11-22 2016-09-13 Genzyme Corp Nuevos metodos para tratar enfermedades neurodegenerativas.
RS65563B1 (sr) 2018-03-16 2024-06-28 Immunic Ag Novi polimorfi kalcijumove soli kao anti-inflamatorni, imunomodulatorni i anti-proliferativni agensi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178596C (nl) * 1975-06-05 1986-04-16 Hoechst Ag Werkwijze voor het bereiden van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor het bereiden van daarin als geneeskrachtige verbindingen te gebruiken 5-methylisoxazool-4-carbonzuuraniliden.
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
US4935434A (en) * 1988-01-26 1990-06-19 Bristol-Myers Company Antiarthritic isoxazole-4-carboxamides
GB9209330D0 (en) * 1992-04-30 1992-06-17 Roussel Lab Ltd Chemical compounds

Also Published As

Publication number Publication date
GB9320299D0 (en) 1993-11-17
CA2133140C (en) 2006-07-25
US5506249A (en) 1996-04-09
JPH07149743A (ja) 1995-06-13
GR3034023T3 (en) 2000-11-30
JP3723589B2 (ja) 2005-12-07
CA2133140A1 (en) 1995-04-02
DE69424734D1 (de) 2000-07-06
EP0646578B1 (fr) 2000-05-31
ATE193531T1 (de) 2000-06-15
DE69424734T2 (de) 2000-11-16
ES2146643T3 (es) 2000-08-16
PT646578E (pt) 2000-09-29
EP0646578A1 (fr) 1995-04-05
US5476866A (en) 1995-12-19

Similar Documents

Publication Publication Date Title
ES2044187T3 (es) Mercapto-4 butiramidas n-mono o n,n-disubstituidas por un radical mono o polihidroxialquilo, y su utilizacion como agentes reductores en un procedimiento para la deformacion permanente del cabello.
JPS568361A (en) Pyroglutamic acid derivative and analogue
ZA919181B (en) Oxazolopyridine derivatives,processes for preparing these and pharmaceutical compositions containing them
DK0646578T3 (da) Phenylcarboxamidisoxazoler og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmace
PH25859A (en) Composition for treatment of ischemic disorder
ES2123039T3 (es) Nuevas 3-(hidroxi-bencilidenil)-indolin-2-onas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ATE83773T1 (de) 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
DK0573318T3 (da) 4-phenylcarbamoyl-3-isoxazolcarboxylsyreforbindelser, fremgangsmåde til deres fremstilling, farmaceutiske præparater med in
FR2713085B1 (fr) Composition tinctoriale contenant des p-phénylènediamines soufrées et procédés de teinture correspondants, nouvelles p-phénylènediamines soufrées et leur procédé de préparation.
ES2103440T3 (es) Nuevas amidas y sulfonamidas naftalenicas, procedimiento de preparacion y composiciones farmaceuticas que las contienen.
FI935318A (fi) 15-deoksispergualiinianalogit, menetelmä niiden valmistamiseksi ja niiden käyttö terapiassa
DE69102477D1 (de) 3-Aminochroman-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.
GB1550496A (en) 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications
DK0732332T3 (da) Substituerede benzothienylpiperaziner, deres anvendelse som lægemidler og fremgangsmåder til fremstilling deraf
DK0387489T3 (da) Anvendelse af 2,2,6,6-tetramethyl-4-aminopiperidinamider som fungicider
ES8702379A1 (es) Un procedimiento para la produccion de 1h-tetrazol-5-carboxamidas-n-sustituidas.
ES2123728T3 (es) Derivados de pirrolo-pirazina de actividad 5-ht3.
SE7403176L (es)
NZ216125A (en) Isoxazoles and pharmaceutical compositions
DK13986A (da) N-(phosphonomethylglycyl)-sulfonylaminer og landbrugsmaessigt acceptable salte deraf, deres fremstilling og anvendelse som herbicider
ES8900162A1 (es) Procedimiento para la obtencion de 3-acilaminobenzisotiazol-s,s-dioxidos
FI903701A0 (fi) Reninhaemmande amino-oligohydroxiderivat.
DK553482A (da) Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider
DE68922596D1 (de) 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1-azabicycloheptan, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen.
DK0424248T3 (da) 20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf