GR3034023T3 - Phenyl carboxamide-isoxazole-derivatives and salts, process for their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. - Google Patents
Phenyl carboxamide-isoxazole-derivatives and salts, process for their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them.Info
- Publication number
- GR3034023T3 GR3034023T3 GR20000401711T GR20000401711T GR3034023T3 GR 3034023 T3 GR3034023 T3 GR 3034023T3 GR 20000401711 T GR20000401711 T GR 20000401711T GR 20000401711 T GR20000401711 T GR 20000401711T GR 3034023 T3 GR3034023 T3 GR 3034023T3
- Authority
- GR
- Greece
- Prior art keywords
- group
- carbon atoms
- salts
- preparation
- isoxazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939320299A GB9320299D0 (en) | 1993-10-01 | 1993-10-01 | Isoxazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3034023T3 true GR3034023T3 (en) | 2000-11-30 |
Family
ID=10742865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20000401711T GR3034023T3 (en) | 1993-10-01 | 2000-07-26 | Phenyl carboxamide-isoxazole-derivatives and salts, process for their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. |
Country Status (11)
Country | Link |
---|---|
US (2) | US5476866A (el) |
EP (1) | EP0646578B1 (el) |
JP (1) | JP3723589B2 (el) |
AT (1) | ATE193531T1 (el) |
CA (1) | CA2133140C (el) |
DE (1) | DE69424734T2 (el) |
DK (1) | DK0646578T3 (el) |
ES (1) | ES2146643T3 (el) |
GB (1) | GB9320299D0 (el) |
GR (1) | GR3034023T3 (el) |
PT (1) | PT646578E (el) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5721277A (en) * | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
DE19539638A1 (de) * | 1995-10-25 | 1997-04-30 | Hoechst Ag | Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen |
CA2302438A1 (en) * | 1997-05-19 | 1998-11-26 | Sugen, Inc. | Heteroarylcarboxamide compounds active against protein tyrosine kinase related disorders |
US6316479B1 (en) | 1997-05-19 | 2001-11-13 | Sugen, Inc. | Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders |
ATE207065T1 (de) | 1997-08-08 | 2001-11-15 | Aventis Pharma Gmbh | Kristallform von n-(4-trifluormethylphenyl)-5- methylisoxazol-4-carbonsäureamid |
US6579880B2 (en) | 2000-06-06 | 2003-06-17 | Ortho-Mcneil Pharmaceutical, Inc. | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 |
WO2002007783A2 (en) * | 2000-07-20 | 2002-01-31 | Regents Of The University Of Minnesota | Radiolabeled immunotoxins |
WO2003006424A1 (en) | 2001-07-10 | 2003-01-23 | 4Sc Ag | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
KR20030063046A (ko) * | 2002-01-22 | 2003-07-28 | 주식회사 엘지생명과학 | 엘비84068을 함유하는 염증으로 인한 질환의 예방 및치료용 조성물 및 이를 포함하는 제제 |
NZ541382A (en) | 2002-12-23 | 2009-04-30 | 4Sc Ag | Aromatic compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
UA108760C2 (uk) | 2010-07-01 | 2015-06-10 | Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби | |
CN105916522A (zh) | 2013-11-22 | 2016-08-31 | 建新公司 | 用于治疗神经变性疾病的新方法 |
CN111836795B (zh) | 2018-03-16 | 2024-03-29 | 埃慕尼克股份公司 | 作为抗炎剂、免疫调节剂和抗增殖剂的钙盐多晶型物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL178596C (nl) * | 1975-06-05 | 1986-04-16 | Hoechst Ag | Werkwijze voor het bereiden van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor het bereiden van daarin als geneeskrachtige verbindingen te gebruiken 5-methylisoxazool-4-carbonzuuraniliden. |
GB8619432D0 (en) * | 1986-08-08 | 1986-09-17 | Lilly Industries Ltd | Pharmaceutical compounds |
US4935434A (en) * | 1988-01-26 | 1990-06-19 | Bristol-Myers Company | Antiarthritic isoxazole-4-carboxamides |
GB9209330D0 (en) * | 1992-04-30 | 1992-06-17 | Roussel Lab Ltd | Chemical compounds |
-
1993
- 1993-10-01 GB GB939320299A patent/GB9320299D0/en active Pending
-
1994
- 1994-08-22 US US08/293,840 patent/US5476866A/en not_active Expired - Lifetime
- 1994-09-28 CA CA002133140A patent/CA2133140C/en not_active Expired - Lifetime
- 1994-09-29 DK DK94402183T patent/DK0646578T3/da active
- 1994-09-29 JP JP25902694A patent/JP3723589B2/ja not_active Expired - Lifetime
- 1994-09-29 ES ES94402183T patent/ES2146643T3/es not_active Expired - Lifetime
- 1994-09-29 EP EP94402183A patent/EP0646578B1/fr not_active Expired - Lifetime
- 1994-09-29 AT AT94402183T patent/ATE193531T1/de active
- 1994-09-29 PT PT94402183T patent/PT646578E/pt unknown
- 1994-09-29 DE DE69424734T patent/DE69424734T2/de not_active Expired - Lifetime
- 1994-12-05 US US08/350,255 patent/US5506249A/en not_active Expired - Lifetime
-
2000
- 2000-07-26 GR GR20000401711T patent/GR3034023T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0646578A1 (fr) | 1995-04-05 |
CA2133140A1 (en) | 1995-04-02 |
EP0646578B1 (fr) | 2000-05-31 |
JP3723589B2 (ja) | 2005-12-07 |
PT646578E (pt) | 2000-09-29 |
ATE193531T1 (de) | 2000-06-15 |
US5476866A (en) | 1995-12-19 |
DE69424734T2 (de) | 2000-11-16 |
GB9320299D0 (en) | 1993-11-17 |
ES2146643T3 (es) | 2000-08-16 |
DE69424734D1 (de) | 2000-07-06 |
US5506249A (en) | 1996-04-09 |
CA2133140C (en) | 2006-07-25 |
DK0646578T3 (da) | 2000-10-30 |
JPH07149743A (ja) | 1995-06-13 |
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