ATE83773T1 - 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. - Google Patents
3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.Info
- Publication number
- ATE83773T1 ATE83773T1 AT88100798T AT88100798T ATE83773T1 AT E83773 T1 ATE83773 T1 AT E83773T1 AT 88100798 T AT88100798 T AT 88100798T AT 88100798 T AT88100798 T AT 88100798T AT E83773 T1 ATE83773 T1 AT E83773T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- alkyl
- branched
- straight chained
- pyridazinone
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 11
- 239000001257 hydrogen Substances 0.000 abstract 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 10
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 229910052736 halogen Chemical group 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1023187 | 1987-01-20 | ||
| EP88100798A EP0275997B1 (de) | 1987-01-20 | 1988-01-20 | 3(2H)Pyridazinon, Verfahren zu dessen Herstellung und dieses enthaltendes Mittel gegen SRS-A |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE83773T1 true ATE83773T1 (de) | 1993-01-15 |
Family
ID=11744513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88100798T ATE83773T1 (de) | 1987-01-20 | 1988-01-20 | 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4978665A (de) |
| EP (1) | EP0275997B1 (de) |
| AT (1) | ATE83773T1 (de) |
| AU (1) | AU597141B2 (de) |
| CA (1) | CA1324792C (de) |
| DD (1) | DD287497A5 (de) |
| DE (2) | DE3876813T4 (de) |
| HU (1) | HU198696B (de) |
| SU (1) | SU1584750A3 (de) |
| ZA (1) | ZA88309B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| IE62890B1 (en) * | 1988-12-06 | 1995-03-08 | Hafslund Nycomed Pharma | New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure |
| JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
| DE4009761A1 (de) * | 1989-07-28 | 1991-01-31 | Bayer Ag | 2h-pyridazinon-derivate |
| HU208124B (en) * | 1990-04-25 | 1993-08-30 | Nissan Chemical Ind Ltd | Process for producing pyridazinone derivatives and pharmaceutical compositions comprising such derivatives as active ingredient |
| JPH0517357A (ja) * | 1991-07-05 | 1993-01-26 | Nissan Chem Ind Ltd | 血小板減少療法剤 |
| IL110040A (en) * | 1993-06-29 | 2000-07-16 | Nissan Chemical Ind Ltd | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
| AU681694B2 (en) * | 1993-09-06 | 1997-09-04 | Ishihara Sangyo Kaisha Ltd. | Pyridazinone derivatives or their salts, processes for theirproduction, and anti-shock agents containing them |
| NZ270130A (en) * | 1993-12-16 | 1995-12-21 | Nihon Nohyaku Co Ltd | Pyridazinone derivatives, preparation and pharmaceutical compositions thereof |
| KR100318653B1 (ko) * | 1994-01-25 | 2002-04-22 | 도쿠시마 히데이치 | 피리다지논유도체 |
| IL112695A (en) * | 1994-02-22 | 1999-04-11 | Green Cross Corp | Pharmaceutical compositions containing pyridazinone derivatives |
| DE19516350A1 (de) * | 1995-05-04 | 1996-11-07 | Du Pont Deutschland | Photothermographisches lichtempfindliches Aufzeichnungsmaterial mit vermindertem Schleier |
| NZ512754A (en) * | 1998-12-07 | 2002-10-25 | Nissan Chemical Ind Ltd | Remedial agent for erectile dysfunction containing a 3(2H)-pyridazinone derivative |
| US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| US7132445B2 (en) | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| MXPA04003439A (es) | 2001-10-12 | 2004-07-08 | Schering Corp | Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc. |
| US6878709B2 (en) | 2002-01-04 | 2005-04-12 | Schering Corporation | 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists |
| EP1485089B1 (de) | 2002-03-18 | 2013-04-17 | Merck Sharp & Dohme Corp. | Kombinationsbehandlungen für chemokine-bedingte erkrankungen |
| PE20040570A1 (es) | 2002-10-09 | 2004-08-30 | Pharmacopeia Drug Discovery | Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocina |
| EP1694659B8 (de) | 2003-12-19 | 2008-10-08 | Schering Corporation | Thiadiazole als cxc- und cc-chemokinrezeptorliganden |
| CA2550540A1 (en) | 2003-12-22 | 2005-07-28 | Schering Corporation | Isothiazole dioxides as cxc- and cc- chemokine receptor ligands |
| MX2008000366A (es) | 2005-06-29 | 2008-03-07 | Schering Corp | Oxadiazoles di-sustituidos como ligandos del receptor cxc-quimiocina. |
| WO2007005403A1 (en) | 2005-06-29 | 2007-01-11 | Schering Corporation | 5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as cxc-chemokine receptor ligands |
| IL281497B2 (en) * | 2018-09-27 | 2024-03-01 | Fmc Corp | Intermediates for preparing herbicidal pyridazinones |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA784639A (en) * | 1968-05-07 | C. Olson Harold | Herbicidal compositions | |
| FR1441438A (fr) * | 1963-11-13 | 1966-06-10 | Basf Ag | Procédé pour la préparation de nitro-4 amino-5 pyridazones-6 |
| FR1413955A (fr) * | 1964-06-03 | 1965-10-15 | Basf Ag | Procédé pour la préparation d'amino-4 halogéno-5 pyridazones-6 |
| US4296120A (en) * | 1980-08-28 | 1981-10-20 | Pfizer Inc. | (Carboxy-oxo-pyrrolidino)phenylalkenamides and esters thereof as SRS-A antagonists |
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| JPH0641454B2 (ja) * | 1985-02-27 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| US4892947A (en) * | 1985-04-27 | 1990-01-09 | Nissan Chemical Industries Ltd. | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it |
-
1988
- 1988-01-15 HU HU88152A patent/HU198696B/hu not_active IP Right Cessation
- 1988-01-15 US US07/144,173 patent/US4978665A/en not_active Expired - Fee Related
- 1988-01-18 ZA ZA880309A patent/ZA88309B/xx unknown
- 1988-01-18 CA CA000556722A patent/CA1324792C/en not_active Expired - Fee Related
- 1988-01-19 AU AU10396/88A patent/AU597141B2/en not_active Ceased
- 1988-01-19 DD DD88312298A patent/DD287497A5/de not_active IP Right Cessation
- 1988-01-19 SU SU884355078A patent/SU1584750A3/ru active
- 1988-01-20 AT AT88100798T patent/ATE83773T1/de not_active IP Right Cessation
- 1988-01-20 DE DE3876813T patent/DE3876813T4/de not_active Expired - Lifetime
- 1988-01-20 DE DE8888100798A patent/DE3876813D1/de not_active Expired - Fee Related
- 1988-01-20 EP EP88100798A patent/EP0275997B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1039688A (en) | 1988-07-21 |
| HUT46313A (en) | 1988-10-28 |
| US4978665A (en) | 1990-12-18 |
| EP0275997B1 (de) | 1992-12-23 |
| EP0275997A1 (de) | 1988-07-27 |
| ZA88309B (en) | 1988-07-01 |
| SU1584750A3 (ru) | 1990-08-07 |
| DD287497A5 (de) | 1991-02-28 |
| DE3876813T2 (de) | 1993-04-29 |
| DE3876813T4 (de) | 1995-05-11 |
| DE3876813D1 (de) | 1993-02-04 |
| CA1324792C (en) | 1993-11-30 |
| AU597141B2 (en) | 1990-05-24 |
| HU198696B (en) | 1989-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3876813D1 (de) | 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. | |
| JPS568361A (en) | Pyroglutamic acid derivative and analogue | |
| FI892787A0 (fi) | Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi | |
| MY102866A (en) | Amide derivatives. | |
| EP0787726A4 (de) | ||
| TW368501B (en) | 7-(2-aminoethyl)-benzothiazolones | |
| NO933452D0 (no) | Et terapeutisk middel for parkinson's sykdom | |
| GB0018272D0 (en) | Chemical compounds IV | |
| DE69129175D1 (de) | 1-Methylcarbapenemderivate und Verfahren zu ihrer Herstellung | |
| ATE44748T1 (de) | 4-substituierte 6-alkylidene-androsten-3,17-dion- derivate und verfahren zu ihrer herstellung. | |
| CO4980887A1 (es) | Nueva 3,4-diariltiazolina-2-uno o 2-tiono derivados, sus metodos de preparacion y su uso terapeutico | |
| ATE53032T1 (de) | 2-thiazolylimidazo(1,2-a)pyrimidine und ihre salze, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und diese enthaltende zubereitungen. | |
| ES2073258T3 (es) | Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica. | |
| NZ221699A (en) | Pyridazinone derivatives; pharmaceutical compositions and intermediates | |
| GB9209330D0 (en) | Chemical compounds | |
| GR3005961T3 (de) | ||
| ES467069A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol | |
| MY109714A (en) | Process for preparing 8-chloroquinolone derivatives | |
| AP1518A (en) | Novel octahydro-6, 10-dioxo-6h-pyridazino/1,2-a/ /1,2/diazepin-1-carboxylic acid derivatives, preparation method and use for preparing therapeutically active compounds. | |
| ZA807337B (en) | 2-phenylamino-imidazolines-(2),processes for their preparation,and pharmaceutical compositions thereof | |
| NZ504299A (en) | 1-aza-2-alkyl-6-aryl-cycloalkane compounds, a process for their preparation and pharmaceutical compositions containing them | |
| ES479110A1 (es) | Procedimiento para preparar derivados de benzamidina. | |
| ATE52509T1 (de) | Thiazolidinderivate und verfahren zu ihrer herstellung. | |
| DE69303352D1 (de) | Verfahren zur Herstellung 5-Pyrazolomerkaptan-Derivate und dessen zwischenprodukte | |
| ATE53839T1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |