DK0646379T3 - Insulinformulering - Google Patents
InsulinformuleringInfo
- Publication number
- DK0646379T3 DK0646379T3 DK94305883T DK94305883T DK0646379T3 DK 0646379 T3 DK0646379 T3 DK 0646379T3 DK 94305883 T DK94305883 T DK 94305883T DK 94305883 T DK94305883 T DK 94305883T DK 0646379 T3 DK0646379 T3 DK 0646379T3
- Authority
- DK
- Denmark
- Prior art keywords
- insulin
- formulation
- zinc
- total
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/106,106 US5534488A (en) | 1993-08-13 | 1993-08-13 | Insulin formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0646379T3 true DK0646379T3 (da) | 2001-12-03 |
Family
ID=22309529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94305883T DK0646379T3 (da) | 1993-08-13 | 1994-08-09 | Insulinformulering |
Country Status (27)
Country | Link |
---|---|
US (1) | US5534488A (es) |
EP (1) | EP0646379B1 (es) |
JP (1) | JPH07149660A (es) |
KR (1) | KR950005324A (es) |
CN (1) | CN1109364A (es) |
AT (1) | ATE207761T1 (es) |
AU (1) | AU674975B2 (es) |
BR (1) | BR9403204A (es) |
CA (1) | CA2129763A1 (es) |
CO (1) | CO4230235A1 (es) |
CZ (1) | CZ193794A3 (es) |
DE (1) | DE69428860T2 (es) |
DK (1) | DK0646379T3 (es) |
ES (1) | ES2164691T3 (es) |
HU (1) | HUT67853A (es) |
IL (1) | IL110581A0 (es) |
NO (1) | NO942959L (es) |
NZ (1) | NZ264197A (es) |
PE (1) | PE14495A1 (es) |
PH (1) | PH30757A (es) |
PL (1) | PL177002B1 (es) |
PT (1) | PT646379E (es) |
RU (1) | RU2135205C1 (es) |
TW (1) | TW326394B (es) |
UA (1) | UA27874C2 (es) |
YU (1) | YU50494A (es) |
ZA (1) | ZA945939B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5578238A (en) * | 1992-10-30 | 1996-11-26 | Lord Corporation | Magnetorheological materials utilizing surface-modified particles |
AR002976A1 (es) * | 1995-03-31 | 1998-05-27 | Lilly Co Eli | Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas |
EP1396272A1 (en) * | 1997-12-23 | 2004-03-10 | Eli Lilly & Company | Insoluble Insulin Compositions for Controlling Blood Glucose |
CO4970787A1 (es) * | 1997-12-23 | 2000-11-07 | Lilly Co Eli | Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea |
US6956021B1 (en) * | 1998-08-25 | 2005-10-18 | Advanced Inhalation Research, Inc. | Stable spray-dried protein formulations |
WO2001000675A1 (en) * | 1999-06-29 | 2001-01-04 | Eli Lilly And Company | Protamine-free insoluble acylated insulin compositions |
US7678364B2 (en) | 1999-08-25 | 2010-03-16 | Alkermes, Inc. | Particles for inhalation having sustained release properties |
AU4935701A (en) * | 2000-03-24 | 2001-10-08 | Genentech Inc | Use of insulin for the treatment of cartilagenous disorders |
EP1247283B1 (en) | 2000-10-06 | 2006-08-16 | The Adviser - Defence Research & Development Organisation | A magneto sensitive fluid composition and a process for preparation thereof |
WO2002045102A1 (en) * | 2000-11-29 | 2002-06-06 | The Adviser Defence Research & Development Organisation, Ministry Of Defence, Government Of India | A magnetorheological fluid composition and a process for preparation thereof |
JP4489352B2 (ja) * | 2001-02-09 | 2010-06-23 | ジェネンテック, インコーポレイテッド | Igf−1の結晶化 |
DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
CA2471144C (en) | 2002-01-09 | 2011-06-07 | Emisphere Technologies, Inc. | Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate |
DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
CA2553392A1 (en) * | 2004-01-16 | 2005-08-11 | Biodel Inc | Sublingual drug delivery device |
US20080096800A1 (en) * | 2004-03-12 | 2008-04-24 | Biodel, Inc. | Rapid mucosal gel or film insulin compositions |
PT2319500E (pt) * | 2004-03-12 | 2013-01-23 | Biodel Inc | Composições de distribuição de fármacos de actuação rápida |
US20080090753A1 (en) * | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
US20080085298A1 (en) * | 2004-03-12 | 2008-04-10 | Biodel, Inc. | Rapid Mucosal Gel or Film Insulin Compositions |
SG153039A1 (en) | 2004-05-06 | 2009-06-29 | Emisphere Tech Inc | Crystalline polymorphic forms of monosodium n-[8- (2hydroxybenzoyl)amino]caprylate |
AU2005249410A1 (en) * | 2004-05-14 | 2005-12-15 | Emisphere Technologies, Inc. | Aryl ketone compounds and compositions for delivering active agents |
WO2006014673A2 (en) | 2004-07-19 | 2006-02-09 | Nobex Corporation | Insulin-oligomer conjugates, formulations and uses thereof |
WO2006017541A2 (en) * | 2004-08-03 | 2006-02-16 | Emisphere Technologies, Inc. | Antidiabetic oral insulin-biguanide combination |
US20060078622A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
US8084420B2 (en) * | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
US7713929B2 (en) * | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
EP2012817A2 (en) * | 2006-04-12 | 2009-01-14 | Biodel, Inc. | Rapid acting and long acting insulin combination formulations |
ES2579229T3 (es) | 2007-03-13 | 2016-08-08 | Jds Therapeutics, Llc | Procedimientos y composiciones para la liberación sostenida de cromo |
WO2008124522A2 (en) * | 2007-04-04 | 2008-10-16 | Biodel, Inc. | Amylin formulations |
WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
PL2203181T3 (pl) | 2007-10-16 | 2018-07-31 | Biocon Limited | Podawana doustnie stała kompozycja farmaceutyczna i jej sposób |
CA2711561A1 (en) * | 2008-01-04 | 2009-07-16 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
CA3016451A1 (en) | 2008-10-17 | 2010-04-22 | Sanofi-Aventis Deutschland Gmbh | Combination of an insulin and a glp-1 agonist |
US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
ES2534191T3 (es) | 2009-11-13 | 2015-04-20 | Sanofi-Aventis Deutschland Gmbh | Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina |
NZ599847A (en) | 2009-11-13 | 2013-09-27 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a glp-1 agonist and methionine |
SG183106A1 (en) * | 2010-02-22 | 2012-09-27 | Univ Case Western Reserve | Long-acting insulin analogue preparations in soluble and crystalline forms |
US20140148384A1 (en) | 2010-08-30 | 2014-05-29 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
EP2680861B1 (en) | 2011-03-01 | 2022-05-04 | Nutrition 21, LLC | Compositions of insulin and chromium for the treatment and prevention of diabetes, hypoglycemia and related disorders |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
AR087744A1 (es) | 2011-09-01 | 2014-04-16 | Sanofi Aventis Deutschland | Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa |
HUE062573T2 (hu) | 2014-12-12 | 2023-11-28 | Sanofi Aventis Deutschland | Glargin inzulin/lixiszenatid rögzített arányú készítmény |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
WO2017139337A1 (en) | 2016-02-11 | 2017-08-17 | Nutrition 21, Llc | Chromium containing compositions for improving health and fitness |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2626228A (en) * | 1945-05-17 | 1953-01-20 | Novo Terapeutisk Labor As | Method of producing crystalline insulin |
US2882202A (en) * | 1950-04-05 | 1959-04-14 | Novo Terapeutisk Labor As | Insulin crystal preparations and methods of producing them |
US2882203A (en) * | 1951-06-26 | 1959-04-14 | Novo Terapeutisk Labor As | Injectable insulin preparation with protracted effect |
US2849370A (en) * | 1953-06-04 | 1958-08-26 | Novo Terapeutisk Labortorium A | Injectable insulin preparations with protracted effect and process of producing same |
US3102077A (en) * | 1953-08-19 | 1963-08-27 | Christensen Henry Marinus | Preparation of insulin containing 2.75 to 8 percent zinc content |
US2819999A (en) * | 1953-11-13 | 1958-01-14 | Novo Terapeutisk Labor As | Process for crystallization of insulin using freeze dried insulin as seeding material |
US2799622A (en) * | 1953-11-14 | 1957-07-16 | Novo Terapeutisk Labor As | Process of producing insulin crystals of substantially uniform size and compositions thereof |
US3060093A (en) * | 1957-07-18 | 1962-10-23 | Nordisk Insulinlab | Slowly acting insulin preparation in crystalline form and method of preparation |
DE2933946A1 (de) * | 1979-08-22 | 1981-03-12 | Hoechst Ag, 6000 Frankfurt | Insulinkristallsuspension und verfahren zu ihrer herstellung. |
FI78616C (fi) * | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
PH23446A (en) * | 1986-10-20 | 1989-08-07 | Novo Industri As | Peptide preparations |
DE3827533A1 (de) * | 1988-08-13 | 1990-02-15 | Hoechst Ag | Pharmazeutische zubereitung zur behandlung des diabetes mellitus |
-
1993
- 1993-08-13 US US08/106,106 patent/US5534488A/en not_active Expired - Fee Related
-
1994
- 1994-08-04 HU HU9402287A patent/HUT67853A/hu unknown
- 1994-08-08 ZA ZA945939A patent/ZA945939B/xx unknown
- 1994-08-08 PE PE1994248043A patent/PE14495A1/es not_active Application Discontinuation
- 1994-08-08 IL IL11058194A patent/IL110581A0/xx not_active IP Right Cessation
- 1994-08-08 NZ NZ264197A patent/NZ264197A/en unknown
- 1994-08-08 BR BR9403204A patent/BR9403204A/pt not_active Application Discontinuation
- 1994-08-09 EP EP94305883A patent/EP0646379B1/en not_active Expired - Lifetime
- 1994-08-09 PH PH48764A patent/PH30757A/en unknown
- 1994-08-09 PL PL94304600A patent/PL177002B1/pl unknown
- 1994-08-09 TW TW083107259A patent/TW326394B/zh active
- 1994-08-09 DK DK94305883T patent/DK0646379T3/da active
- 1994-08-09 CA CA002129763A patent/CA2129763A1/en not_active Abandoned
- 1994-08-09 KR KR1019940019550A patent/KR950005324A/ko active IP Right Grant
- 1994-08-09 AT AT94305883T patent/ATE207761T1/de not_active IP Right Cessation
- 1994-08-09 UA UA94085696A patent/UA27874C2/uk unknown
- 1994-08-09 ES ES94305883T patent/ES2164691T3/es not_active Expired - Lifetime
- 1994-08-09 CO CO94035010A patent/CO4230235A1/es unknown
- 1994-08-09 PT PT94305883T patent/PT646379E/pt unknown
- 1994-08-09 DE DE69428860T patent/DE69428860T2/de not_active Expired - Fee Related
- 1994-08-09 NO NO942959A patent/NO942959L/no not_active Application Discontinuation
- 1994-08-09 RU RU94028671A patent/RU2135205C1/ru active
- 1994-08-10 CN CN94109082A patent/CN1109364A/zh active Pending
- 1994-08-10 CZ CZ941937A patent/CZ193794A3/cs unknown
- 1994-08-10 JP JP6188204A patent/JPH07149660A/ja not_active Withdrawn
- 1994-08-10 YU YU50494A patent/YU50494A/sh unknown
- 1994-08-12 AU AU70247/94A patent/AU674975B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ATE207761T1 (de) | 2001-11-15 |
KR950005324A (ko) | 1995-03-20 |
AU7024794A (en) | 1995-02-23 |
PT646379E (pt) | 2002-03-28 |
HU9402287D0 (en) | 1994-09-28 |
PE14495A1 (es) | 1995-06-02 |
NZ264197A (en) | 1997-01-29 |
CA2129763A1 (en) | 1995-02-14 |
UA27874C2 (uk) | 2000-10-16 |
PL304600A1 (en) | 1995-02-20 |
CZ193794A3 (en) | 1995-03-15 |
JPH07149660A (ja) | 1995-06-13 |
IL110581A0 (en) | 1994-11-11 |
RU2135205C1 (ru) | 1999-08-27 |
NO942959L (no) | 1995-02-14 |
TW326394B (en) | 1998-02-11 |
AU674975B2 (en) | 1997-01-16 |
PL177002B1 (pl) | 1999-09-30 |
DE69428860D1 (de) | 2001-12-06 |
CO4230235A1 (es) | 1995-10-19 |
YU50494A (sh) | 1997-01-08 |
HUT67853A (en) | 1995-05-29 |
ZA945939B (en) | 1996-02-08 |
NO942959D0 (no) | 1994-08-09 |
CN1109364A (zh) | 1995-10-04 |
BR9403204A (pt) | 1995-04-18 |
DE69428860T2 (de) | 2002-05-02 |
ES2164691T3 (es) | 2002-03-01 |
EP0646379A1 (en) | 1995-04-05 |
EP0646379B1 (en) | 2001-10-31 |
PH30757A (en) | 1997-10-17 |
US5534488A (en) | 1996-07-09 |
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