DK0612352T3 - Diagnostiske anvendelser af dobbelt-D-sløjfedannelse - Google Patents

Diagnostiske anvendelser af dobbelt-D-sløjfedannelse

Info

Publication number
DK0612352T3
DK0612352T3 DK92918877.9T DK92918877T DK0612352T3 DK 0612352 T3 DK0612352 T3 DK 0612352T3 DK 92918877 T DK92918877 T DK 92918877T DK 0612352 T3 DK0612352 T3 DK 0612352T3
Authority
DK
Denmark
Prior art keywords
pct
date
probe
dna
double
Prior art date
Application number
DK92918877.9T
Other languages
Danish (da)
English (en)
Inventor
Elissa P Sena
Cornelia J Calhoun
David A Zarling
Original Assignee
Daikin Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/520,321 external-priority patent/US5223414A/en
Priority claimed from US07/755,462 external-priority patent/US5273881A/en
Application filed by Daikin Ind Ltd filed Critical Daikin Ind Ltd
Application granted granted Critical
Publication of DK0612352T3 publication Critical patent/DK0612352T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK92918877.9T 1990-05-07 1992-09-04 Diagnostiske anvendelser af dobbelt-D-sløjfedannelse DK0612352T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/520,321 US5223414A (en) 1990-05-07 1990-05-07 Process for nucleic acid hybridization and amplification
US07/755,462 US5273881A (en) 1990-05-07 1991-09-04 Diagnostic applications of double D-loop formation
US91079192A 1992-07-09 1992-07-09

Publications (1)

Publication Number Publication Date
DK0612352T3 true DK0612352T3 (da) 1997-06-30

Family

ID=27414753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92918877.9T DK0612352T3 (da) 1990-05-07 1992-09-04 Diagnostiske anvendelser af dobbelt-D-sløjfedannelse

Country Status (13)

Country Link
US (1) US5670316A (no)
EP (1) EP0612352B1 (no)
JP (1) JP2745816B2 (no)
KR (1) KR100245284B1 (no)
AT (1) ATE153707T1 (no)
AU (1) AU661505B2 (no)
CA (1) CA2116215C (no)
DE (1) DE69220084T2 (no)
DK (1) DK0612352T3 (no)
ES (1) ES2101867T3 (no)
FI (1) FI941016A (no)
NO (1) NO313557B1 (no)
WO (1) WO1993005178A1 (no)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5506098A (en) * 1991-09-04 1996-04-09 Daikin Industries, Ltd. In situ hybridization method
WO1993022443A1 (en) * 1992-04-24 1993-11-11 Sri International In vivo homologous sequence targeting in eukaryotic cells
US5929043A (en) * 1995-01-31 1999-07-27 Pangene Corporation Recombinase mediated DNA therapies
FR2737502B1 (fr) * 1995-07-31 1997-10-24 Genset Sa Procede de detection d'acides nucleiques utilisant des sondes nucleotidiques permettant a la fois une capture specifique et une detection
WO1998008975A1 (en) * 1996-08-29 1998-03-05 Daikin Industries, Ltd. Methods for targeting, enriching, detecting and/or isolating target nucleic acid sequence using reca-like recombinase
JP3891620B2 (ja) * 1996-11-14 2007-03-14 株式会社アイシン・コスモス研究所 ヘアピン型構造の核酸プローブ分子、及び該核酸プローブ分子を利用した核酸検出方法
US5948653A (en) * 1997-03-21 1999-09-07 Pati; Sushma Sequence alterations using homologous recombination
US6342350B1 (en) * 1997-09-05 2002-01-29 The General Hospital Corporation Alpha-2-macroglobulin diagnostic test
AU762766B2 (en) 1997-12-11 2003-07-03 Napro Biotherapeutics, Inc. The use of consensus sequences for targeted homologous gene isolation and recombination in gene families
EP1068360B1 (de) * 1998-04-01 2003-07-16 ATTO-TEC GmbH Verfahren und vorrichtung zur quantifizierung von dna und rna
US6287772B1 (en) * 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
US6541227B1 (en) * 1998-10-12 2003-04-01 Aisin Seiki Kabushiki Kaisha Preparation of labeled DNA
JP4265028B2 (ja) * 1999-04-14 2009-05-20 アイシン精機株式会社 二本鎖ｄｎａの特異的切断方法およびそのためのキット
AU4657500A (en) 1999-04-21 2000-11-02 Pangene Corporation Locked nucleic acid hybrids and methods of use
BR0016621A (pt) * 1999-12-21 2002-09-03 Johnson & Johnson Detecção de ácidos nucléicos
WO2001048249A2 (en) * 1999-12-28 2001-07-05 Pangene Corporation Recombinase mediated gene chip detection
WO2002077286A1 (en) * 2001-02-21 2002-10-03 Gene Check, Inc. Mutation detection using muts and reca
AU2002303176A1 (en) * 2001-03-27 2002-10-15 University Of Delaware Genomics applications for modified oligonucleotides
CA2444649C (en) * 2001-04-20 2012-10-02 The Penn State Research Foundation Methods for nucleic acid manipulation
US7468244B2 (en) 2001-09-27 2008-12-23 University Of Delaware Polymorphism detection and separation
WO2003027640A2 (en) * 2001-09-28 2003-04-03 University Of Delaware Polymorphism detection and separation
US7244562B2 (en) * 2001-11-01 2007-07-17 Gene Check, Inc. RecA assisted detection of mutations, single nucleotide polymorphisms and specific sequences
JP4340543B2 (ja) * 2002-02-21 2009-10-07 エーエスエム サイエンティフィック， インコーポレイテッド リコンビナーゼポリメラーゼ増幅
US7399590B2 (en) * 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
EP1500710A4 (en) * 2002-05-08 2006-10-04 Arkray Inc METHOD FOR DETECTING TARGET NUCLEIC ACID
AU2003251986A1 (en) * 2002-07-17 2004-02-02 U.S.Genomics, Inc. Methods and compositions for analyzing polymers using chimeric tags
EP1613768A4 (en) * 2003-03-11 2006-05-31 Gene Check Inc RECA-SUPPORTED ALLELSPECIFIC OLIGONUCLEOTIDE EXTENSION PROCESS
EP1651778A1 (en) * 2003-08-01 2006-05-03 U.S. Genomics, Inc. Methods and compositions related to the use of sequence-specific endonucleases for analyzing nucleic acids under non-cleaving conditions
WO2005017205A2 (en) * 2003-08-04 2005-02-24 U. S. Genomics, Inc. Nucleic acid mapping using linear analysis
ES2718482T3 (es) * 2004-06-01 2019-07-02 Alere San Diego Inc Kit para amplificación de recombinasa polimerasa
JP2006055065A (ja) * 2004-08-19 2006-03-02 Toyo Kohan Co Ltd 非対称ｐｃｒを用いた核酸の検出方法、ポリヌクレオチドプローブ、それを固定するプローブ固定化担体およびキット
WO2006051988A1 (ja) * 2004-11-15 2006-05-18 Riken 核酸の増幅方法
JP5027126B2 (ja) * 2005-07-25 2012-09-19 アリーア サン ディエゴ， インコーポレイテッド リコンビナーゼポリメラーゼ増幅を多重化するための方法
US20090064377A1 (en) * 2005-09-29 2009-03-05 Daphne Yvette Rainey-Wittich Method and means for targeted nucleotide exchange
US20070202522A1 (en) * 2006-02-27 2007-08-30 Salinas Frank G Isothermal screening of tumor cell related nucleic acids
US20090061413A1 (en) * 2006-02-27 2009-03-05 Salinas Frank G Isothermal screening of hiv-1 related nucleic acids
US20080003600A1 (en) * 2006-02-27 2008-01-03 Salinas Frank G Isothermal screening of breast cancer related nucleic acid
US20080220421A1 (en) * 2006-02-27 2008-09-11 Salinas Frank G Isothermal screening for nucleic acids associated with diseases and conditions of the gi tract
JP2009535053A (ja) 2006-05-04 2009-10-01 エーエスエム サイエンティフィック， インコーポレイテッド レコンビナーゼポリメラーゼ増幅
EP2432795B1 (en) 2009-05-20 2015-03-04 Alere San Diego, Inc. Dna glycosylase/lyase and ap endonuclease substrates
EP2438196B1 (en) 2009-06-05 2016-12-21 Alere San Diego, Inc. Recombinase polymerase amplification reagents and kits
CN102859003B (zh) 2010-03-08 2014-07-30 达纳-法伯癌症研究院有限公司 使用参考封闭序列的全cold-pcr富集
EP2691541B1 (en) 2011-03-31 2017-10-18 Dana-Farber Cancer Institute, Inc. Method for enriching in single-stranded mutant sequences from mixture of wild-type and mutant sequences
EP2694666B1 (en) 2011-04-07 2018-05-23 Alere San Diego, Inc. Monitoring recombinase polymerase amplification mixtures
EP2839026B1 (en) 2012-04-19 2016-08-10 Life Technologies Corporation Nucleic acid amplification
CN114854832A (zh) 2012-04-19 2022-08-05 生命技术公司 核酸扩增
US20150197787A1 (en) * 2012-08-02 2015-07-16 Qiagen Gmbh Recombinase mediated targeted dna enrichment for next generation sequencing
EP3257952B1 (en) 2012-09-11 2020-02-12 Life Technologies Corporation Nucleic acid amplification
WO2014043143A1 (en) 2012-09-11 2014-03-20 Life Technologies Corporation Nucleic acid amplification
CN106103713B (zh) 2014-02-03 2021-05-28 赛默飞世尔科技波罗的海封闭股份公司 用于经控制dna片段化的方法
EP3155127B1 (en) 2014-06-13 2020-07-22 Life Technologies Corporation Multiplex nucleic acid amplification
JP6698708B2 (ja) 2015-06-09 2020-05-27 ライフ テクノロジーズ コーポレーション 分子タグ付けのための方法、システム、組成物、キット、装置、及びコンピュータ可読媒体
JP6941568B2 (ja) * 2015-06-24 2021-09-29 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド ヌクレアーゼを使用する野生型ｄｎａの選択的分解および突然変異体対立遺伝子の濃縮
EP3387147A1 (en) 2015-12-09 2018-10-17 Life Technologies Corporation Detection and quantification of nucleic acid molecules associated with a surface
US10626383B2 (en) 2016-01-15 2020-04-21 Thermo Fisher Scientific Baltics Uab Thermophilic DNA polymerase mutants
WO2017214561A1 (en) 2016-06-10 2017-12-14 Life Technologies Corporation Methods and compositions for nucleic acid amplification
WO2018071522A1 (en) 2016-10-11 2018-04-19 Life Technologies Corporation Rapid amplification of nucleic acids
EP3551756A4 (en) 2016-12-12 2020-07-15 Dana Farber Cancer Institute, Inc. COMPOSITIONS AND METHODS FOR MOLECULAR BARCODING OF DNA MOLECULES BEFORE MUTATION ENRICHMENT AND / OR MUTATION DETECTION
US11542540B2 (en) 2017-06-16 2023-01-03 Life Technologies Corporation Control nucleic acids, and compositions, kits, and uses thereof
EP3645710A1 (en) 2017-06-26 2020-05-06 Thermo Fisher Scientific Baltics Uab Thermophilic dna polymerase mutants
DE102017114537A1 (de) * 2017-06-29 2019-01-03 Endress+Hauser Conducta Gmbh+Co. Kg Sensormembran, Sensorkappe und optischer Sensor
CN111566223B (zh) 2017-11-07 2024-04-12 生命技术公司 用于操纵核酸的方法和组合物
WO2020227031A1 (en) 2019-05-03 2020-11-12 Life Technologies Corporation Methods and compositions for manipulating nucleic acids
KR20220062302A (ko) 2019-08-21 2022-05-16 라이프 테크놀로지스 코포레이션 시퀀싱을 위한 시스템 및 방법
US20220170093A1 (en) 2020-11-16 2022-06-02 Life Technologies Corporation System and method for sequencing
NL2033124B1 (en) 2022-09-23 2024-03-29 Rapidemic B V Methods and device for multiple-label nucleic acid amplification and detection

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4766062A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay method and polynucleotide complex reagent therefor
CA1254114A (en) * 1984-05-07 1989-05-16 Allied Corporation Displacement polynucleotide assay employing recombination protein and diagnostic kit
JPS61502282A (ja) * 1984-06-01 1986-10-09 ナショナル・バイオメディカル・リサ−チ・ファウンデ−ション 酵素剤を用いた触媒作用による核酸交雑方法
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4888274A (en) * 1985-09-18 1989-12-19 Yale University RecA nucleoprotein filament and methods
AU6403886A (en) * 1985-09-18 1987-04-07 Yale University Reca nucleoprotein filament and methods
EP0322311B1 (en) * 1987-12-21 1994-03-23 Applied Biosystems, Inc. Method and kit for detecting a nucleic acid sequence
AU2735988A (en) * 1987-12-21 1989-07-13 Amoco Corporation Target and background capture methods with amplification for affinity assays
US5223414A (en) * 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
US5273881A (en) * 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
US5506098A (en) * 1991-09-04 1996-04-09 Daikin Industries, Ltd. In situ hybridization method

Also Published As

Publication number Publication date
DE69220084D1 (de) 1997-07-03
ATE153707T1 (de) 1997-06-15
JPH06510201A (ja) 1994-11-17
EP0612352B1 (en) 1997-05-28
EP0612352A1 (en) 1994-08-31
JP2745816B2 (ja) 1998-04-28
KR100245284B1 (ko) 2000-03-02
CA2116215A1 (en) 1993-03-05
US5670316A (en) 1997-09-23
ES2101867T3 (es) 1997-07-16
DE69220084T2 (de) 1997-09-11
FI941016A0 (fi) 1994-03-03
CA2116215C (en) 1998-12-22
WO1993005178A1 (en) 1993-03-18
AU2540192A (en) 1993-04-05
NO313557B1 (no) 2002-10-21
AU661505B2 (en) 1995-07-27
NO940744L (no) 1994-05-02
NO940744D0 (no) 1994-03-03
FI941016A (fi) 1994-05-03

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