DK0603229T3 - Fremgangsmåde til og mellemprodukter ved fremstilling af quinuclidinestere og farmaceutiske præparater indeholdende dem - Google Patents
Fremgangsmåde til og mellemprodukter ved fremstilling af quinuclidinestere og farmaceutiske præparater indeholdende demInfo
- Publication number
- DK0603229T3 DK0603229T3 DK92918526T DK92918526T DK0603229T3 DK 0603229 T3 DK0603229 T3 DK 0603229T3 DK 92918526 T DK92918526 T DK 92918526T DK 92918526 T DK92918526 T DK 92918526T DK 0603229 T3 DK0603229 T3 DK 0603229T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- alkyl
- image
- intermediates
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919119705A GB9119705D0 (en) | 1991-09-14 | 1991-09-14 | Therapeutic compounds |
| PCT/EP1992/002067 WO1993006098A1 (en) | 1991-09-14 | 1992-09-03 | Quinuclidine esters process and intermediate for their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0603229T3 true DK0603229T3 (da) | 1998-10-12 |
Family
ID=10701448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92918526T DK0603229T3 (da) | 1991-09-14 | 1992-09-03 | Fremgangsmåde til og mellemprodukter ved fremstilling af quinuclidinestere og farmaceutiske præparater indeholdende dem |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5543419A (xx) |
| EP (1) | EP0603229B1 (xx) |
| JP (2) | JP2672030B2 (xx) |
| KR (1) | KR0135784B1 (xx) |
| CN (1) | CN1037269C (xx) |
| AT (1) | ATE167187T1 (xx) |
| AU (1) | AU659487B2 (xx) |
| BR (1) | BR9206499A (xx) |
| CA (1) | CA2116356C (xx) |
| CZ (1) | CZ281752B6 (xx) |
| DE (1) | DE69225897T2 (xx) |
| DK (1) | DK0603229T3 (xx) |
| EG (1) | EG20072A (xx) |
| ES (1) | ES2116343T3 (xx) |
| FI (1) | FI114707B (xx) |
| GB (1) | GB9119705D0 (xx) |
| GR (1) | GR3027667T3 (xx) |
| HU (1) | HU220594B1 (xx) |
| IL (1) | IL103078A (xx) |
| MX (1) | MX9205221A (xx) |
| MY (1) | MY108602A (xx) |
| NO (1) | NO305397B1 (xx) |
| NZ (1) | NZ244324A (xx) |
| PL (1) | PL170627B1 (xx) |
| PT (1) | PT100863B (xx) |
| RU (1) | RU2117669C1 (xx) |
| SG (1) | SG50414A1 (xx) |
| TW (1) | TW251285B (xx) |
| UA (1) | UA42686C2 (xx) |
| WO (1) | WO1993006098A1 (xx) |
| ZA (1) | ZA926939B (xx) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2147889T3 (es) * | 1996-01-19 | 2000-10-01 | Lonza Ag | Metodo para preparar 3-hidroxiquinuclidinol opticamente activo. |
| CZ54498A3 (cs) * | 1997-03-07 | 1998-11-11 | Lonza Ag | Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití |
| AU758370B2 (en) * | 1997-08-08 | 2003-03-20 | Duke University | Compositions, apparatus and methods for facilitating surgical procedures |
| US6711436B1 (en) | 1997-08-08 | 2004-03-23 | Duke University | Compositions, apparatus and methods for facilitating surgical procedures |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| PE20020719A1 (es) | 2000-12-22 | 2002-10-11 | Almirall Prodesfarma Ag | Derivados de carbamato de quinuclidina como agentes antimuscarinicos m3 |
| AU2002238471B2 (en) | 2000-12-28 | 2007-06-28 | Almirall, S.A. | Quinuclidine derivatives and their use as M3 antagonists |
| DE102004057995A1 (de) * | 2004-12-01 | 2006-06-08 | Wacker Chemie Ag | Verfahren zur Herstellung von α,α-Dialkyl-α-Hydroxymethyl-Carbonsäurederivaten |
| US20100112061A1 (en) * | 2006-12-13 | 2010-05-06 | William Baker | Monophosphates as Mutual Prodrugs of Muscarinic Receptor Antagonists and Beta-Agonists for the Treatment of COPD And Chronic Bronchitis |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4843074A (en) * | 1988-05-17 | 1989-06-27 | Marion Laboratories, Inc. | 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts |
| GB8923590D0 (en) * | 1989-10-19 | 1989-12-06 | Pfizer Ltd | Antimuscarinic bronchodilators |
-
1991
- 1991-09-14 GB GB919119705A patent/GB9119705D0/en active Pending
-
1992
- 1992-09-03 SG SG1996000871A patent/SG50414A1/en unknown
- 1992-09-03 JP JP5505734A patent/JP2672030B2/ja not_active Expired - Fee Related
- 1992-09-03 CZ CS923953A patent/CZ281752B6/cs not_active IP Right Cessation
- 1992-09-03 DK DK92918526T patent/DK0603229T3/da active
- 1992-09-03 UA UA94005520A patent/UA42686C2/uk unknown
- 1992-09-03 KR KR1019940700816A patent/KR0135784B1/ko not_active IP Right Cessation
- 1992-09-03 EP EP92918526A patent/EP0603229B1/en not_active Expired - Lifetime
- 1992-09-03 US US08/204,260 patent/US5543419A/en not_active Expired - Fee Related
- 1992-09-03 DE DE69225897T patent/DE69225897T2/de not_active Expired - Fee Related
- 1992-09-03 AT AT92918526T patent/ATE167187T1/de not_active IP Right Cessation
- 1992-09-03 WO PCT/EP1992/002067 patent/WO1993006098A1/en active IP Right Grant
- 1992-09-03 RU RU94019411/04A patent/RU2117669C1/ru not_active IP Right Cessation
- 1992-09-03 BR BR9206499A patent/BR9206499A/pt not_active Application Discontinuation
- 1992-09-03 CA CA002116356A patent/CA2116356C/en not_active Expired - Fee Related
- 1992-09-03 HU HU9400729A patent/HU220594B1/hu not_active IP Right Cessation
- 1992-09-03 PL PL92302771A patent/PL170627B1/pl unknown
- 1992-09-03 ES ES92918526T patent/ES2116343T3/es not_active Expired - Lifetime
- 1992-09-03 AU AU24823/92A patent/AU659487B2/en not_active Ceased
- 1992-09-07 IL IL10307892A patent/IL103078A/en not_active IP Right Cessation
- 1992-09-10 TW TW081107184A patent/TW251285B/zh active
- 1992-09-11 ZA ZA926939A patent/ZA926939B/xx unknown
- 1992-09-11 MX MX9205221A patent/MX9205221A/es not_active IP Right Cessation
- 1992-09-11 PT PT100863A patent/PT100863B/pt active IP Right Grant
- 1992-09-14 EG EG54292A patent/EG20072A/xx active
- 1992-09-14 CN CN92110746A patent/CN1037269C/zh not_active Expired - Fee Related
- 1992-09-14 NZ NZ244324A patent/NZ244324A/en unknown
- 1992-09-14 MY MYPI92001642A patent/MY108602A/en unknown
-
1994
- 1994-03-11 FI FI941170A patent/FI114707B/fi not_active IP Right Cessation
- 1994-03-14 NO NO940905A patent/NO305397B1/no unknown
-
1997
- 1997-02-18 JP JP9033807A patent/JP2955533B2/ja not_active Expired - Fee Related
-
1998
- 1998-08-19 GR GR980401846T patent/GR3027667T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0603229T3 (da) | Fremgangsmåde til og mellemprodukter ved fremstilling af quinuclidinestere og farmaceutiske præparater indeholdende dem | |
| TW274547B (xx) | ||
| NZ335363A (en) | Naphthyridine derivatives | |
| GR3034769T3 (en) | Triazole antifungal agents. | |
| MX9700675A (es) | Compuestos utiles como agentes antiproliferativos e inhibidores de la glicinamida ribonucleotido formil transferasa. | |
| AT397654B (de) | Neue pleuromutilinderivate, ihre verwendung und verfahren zu ihrer herstellung | |
| RU94019411A (ru) | Эфиры хинук лидина, промежуточные соединения для их синтеза, фармацевтическая композиция и способ лечения | |
| NO944923L (no) | Hemming av vektökning eller indusering av vekttap | |
| EP0717039A4 (en) | NOVEL TRIAZOL TYPE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PESTICIDE AGENT | |
| UA72934C2 (uk) | Феніл- і піридилтетрагідропіридини, що інгібують фактор некрозу пухлин, спосіб їх одержання та фармацевтична композиція | |
| DE69406451D1 (de) | Verfahren zur herstellung von n-carbonylarylimine als zwischenprodukte in der synthese von therapeutisch aktiven taxol-derivaten | |
| IE821475L (en) | Benzoyl-phenyl-piperidine derivatives | |
| ATE139767T1 (de) | Verfahren zur herstellung 5-pyrazolomerkaptan- derivate und dessen zwischenprodukte | |
| SE8306048D0 (sv) | Neue heterocyclische essigseuren und verfahren zu ihrer herstellung | |
| HUP0303691A2 (hu) | Uretánszármazékok, eljárás az előállításukra és alkalmazásuk gyógyszerkészítmények előállítására |