DK0596036T3 - Indretning til afgivelse gennem huden - Google Patents

Indretning til afgivelse gennem huden

Info

Publication number
DK0596036T3
DK0596036T3 DK92917863.0T DK92917863T DK0596036T3 DK 0596036 T3 DK0596036 T3 DK 0596036T3 DK 92917863 T DK92917863 T DK 92917863T DK 0596036 T3 DK0596036 T3 DK 0596036T3
Authority
DK
Denmark
Prior art keywords
drug
passive
reservoir
active
ionizable
Prior art date
Application number
DK92917863.0T
Other languages
Danish (da)
English (en)
Inventor
Ronald P Haak
Richard J Gyory
Felix Theeuwes
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK0596036T3 publication Critical patent/DK0596036T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444Membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • External Artificial Organs (AREA)
  • Saccharide Compounds (AREA)
  • Surgical Instruments (AREA)
  • Refuse Collection And Transfer (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
DK92917863.0T 1991-07-24 1992-07-22 Indretning til afgivelse gennem huden DK0596036T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/735,126 US5203768A (en) 1991-07-24 1991-07-24 Transdermal delivery device

Publications (1)

Publication Number Publication Date
DK0596036T3 true DK0596036T3 (da) 1995-12-04

Family

ID=24954476

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92917863.0T DK0596036T3 (da) 1991-07-24 1992-07-22 Indretning til afgivelse gennem huden

Country Status (14)

Country Link
US (1) US5203768A (xx)
EP (1) EP0596036B1 (xx)
JP (1) JPH06509254A (xx)
AT (1) ATE127340T1 (xx)
AU (1) AU2426792A (xx)
DE (1) DE69204676T2 (xx)
DK (1) DK0596036T3 (xx)
ES (1) ES2076779T3 (xx)
GR (1) GR3017333T3 (xx)
IE (1) IE71032B1 (xx)
MX (1) MX9204304A (xx)
PT (1) PT100720A (xx)
WO (1) WO1993001807A1 (xx)
ZA (1) ZA925513B (xx)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956032B1 (en) * 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5374241A (en) * 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
US6331318B1 (en) * 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5464387A (en) * 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
FR2687321B1 (fr) * 1992-02-14 1999-04-16 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'une quantite totale donnee d'un principe actif a un sujet.
WO1994010987A1 (en) * 1992-11-09 1994-05-26 Pharmetrix Corporation Combined analgesic delivery methods for pain management
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
US5843015A (en) * 1993-12-28 1998-12-01 Becton Dickinson And Company Molecules for iontophoretic delivery
EP0774272B1 (en) * 1994-06-17 2004-01-28 Hisamitsu Pharmaceutical Co. Inc. Electrode for iontophoresis and device using the same
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5843014A (en) * 1995-03-24 1998-12-01 Alza Corporation Display for an electrotransport delivery device
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
IE960375A1 (en) * 1995-06-05 1996-12-11 Alza Corp Device for transdermal electrotransport delivery of fentanyl¹and sufentanil
US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6216033B1 (en) * 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
AT409720B (de) * 1995-06-05 2002-10-25 Alza Corp Vorrichtung zur selbstverabreichung von analgetika
US7572252B1 (en) * 1995-06-07 2009-08-11 Alza Corporation Electrotransport agent delivery method and apparatus
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
DE69629628T2 (de) 1995-06-14 2004-06-17 Hisamitsu Pharmaceutical Co., Inc., Tosu Schnittstelle für Iontophorese
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
WO1997014473A1 (en) * 1995-10-18 1997-04-24 Novartis Ag Thermopile powered transdermal drug delivery device
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
AU3404097A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
US5848966A (en) * 1997-03-04 1998-12-15 Graphic Controls Corporation Medical device easily removed from skin and a method of removal therefrom
US6119036A (en) 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
US6029083A (en) * 1997-04-04 2000-02-22 Becton, Dickinson And Company Circuit and method for automatically turning off an iontophoresis system
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
WO1999018797A1 (en) 1997-10-09 1999-04-22 Emory University Method and devices for transdermal delivery of lithium
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
KR100289471B1 (ko) * 1998-01-19 2001-09-17 김충섭 휀타닐계마취제의이식형서방성제제
ATE343411T1 (de) * 1998-08-31 2006-11-15 Travanti Pharma Inc Gesteuerte medikamentdosierungsvorrichtung
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6858018B1 (en) * 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
EP1148902A1 (en) * 1999-01-22 2001-10-31 PowderJect Research Limited Method of enhancing needleless transdermal powdered drug delivery
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6553253B1 (en) 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6421561B1 (en) 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US6522918B1 (en) 2000-02-09 2003-02-18 William E. Crisp Electrolytic device
US6496727B1 (en) * 2000-05-31 2002-12-17 Becton, Dickinson And Company Medicament-loaded transdermal reservoir and method for its formation
US6629968B1 (en) * 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
ATE359802T1 (de) * 2002-10-04 2007-05-15 Photokinetix Inc Photokinetische abgabe von biologisch aktiven subtanzen unter verwendung von pulsierendem inkohaerentem licht.
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US20050112151A1 (en) * 2003-11-20 2005-05-26 Horng Liou L. Skin adherent hydrogels
WO2005084275A2 (en) 2004-02-27 2005-09-15 Iomed, Inc. Iontophoretic electrode
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
WO2006133102A2 (en) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Agent delivery system and uses of the same
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
US20090214625A1 (en) * 2005-07-15 2009-08-27 Mizuo Nakayama Drug delivery patch
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
US20090254018A1 (en) * 2005-08-24 2009-10-08 Mizuo Nakayama Electrode assembly for freezing-type iontophoresis device
WO2007026672A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. イオントフォレーシス用汎用性電解液組成物
JPWO2007029611A1 (ja) * 2005-09-06 2009-03-19 Tti・エルビュー株式会社 イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
CA2619665A1 (en) * 2005-09-15 2007-03-22 Tti Ellebeau, Inc. Rod type iontophoresis device
EP1925335A1 (en) * 2005-09-16 2008-05-28 Tti Ellebeau, Inc. Catheter type iontophoresis apparatus
JPWO2007037324A1 (ja) * 2005-09-28 2009-04-09 Tti・エルビュー株式会社 乾燥型イオントフォレーシス用電極構造体
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
RU2008117153A (ru) * 2005-09-30 2009-11-10 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Аппарат для ионтофореза, доставляющий множество активных агентов к биологическим барьерам
JP2009509656A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面に活性物質を送達するイオントフォレーシス装置における動作不良を検出するための方法及びシステム
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
EP1931417A2 (en) * 2005-09-30 2008-06-18 Transcutaneous Technologies Inc. Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
JP2009509657A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2007041323A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic delivery of vesicle-encapsulated active agents
WO2007041526A2 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
JP4902543B2 (ja) * 2005-09-30 2012-03-21 Tti・エルビュー株式会社 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
WO2007037476A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
WO2007046103A2 (en) * 2005-10-19 2007-04-26 Perf-Action Technologies Ltd. System for iontophoretic transdermal delivery of polymeric agents and methods of use thereof
US20070149916A1 (en) * 2005-12-22 2007-06-28 Alza Corporation Dry matrices as drug reservoirs in electrotransport applications
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
WO2007079193A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US20070202156A1 (en) * 2006-02-13 2007-08-30 Aveva Drug Deliverty Systems Adhesive preparation comprising sufentanil and methods of using same
IN2015DN00888A (xx) 2006-02-22 2015-07-10 Mannkind Corp
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
MX2009002321A (es) * 2006-09-05 2009-03-23 Tti Ellebeau Inc Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva.
JP5383497B2 (ja) * 2006-12-01 2014-01-08 Tti・エルビュー株式会社 装置、例として経皮送達装置に給電し且つ/又は当該装置を制御するシステム及び装置
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
MX2009012273A (es) * 2007-05-18 2010-04-09 Tti Ellebeau Inc Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
ES2454974T3 (es) * 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
AR073575A1 (es) * 2008-09-10 2010-11-17 Transcu Ltd Aparato y metodo para dispensar basados en hpc liquidos viscosos en sustratos porosos por ejemplo proceso continuo basado en bandas
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
JP2012529353A (ja) * 2009-06-09 2012-11-22 Tti・エルビュー株式会社 長寿命高容量電極、装置および製造方法
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
KR101955175B1 (ko) 2010-04-13 2019-03-06 나지브 바불 1-메틸-2'-6'-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2904252B2 (en) 2012-10-01 2020-11-25 United Technologies Corporation Static guide vane with internal hollow channels
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN104353183B (zh) * 2014-10-31 2016-12-07 厦门微科格瑞生物科技有限公司 电解液位置固定的可佩戴智能药物导入结构
US12102508B2 (en) * 2016-10-21 2024-10-01 Ohio State Innovation Foundation Antimicrobial wound care dressing
KR20190003316A (ko) * 2017-06-30 2019-01-09 주식회사 엑소코바이오 지방줄기세포 유래의 엑소좀 및/또는 세포외 소포체를 유효성분으로 포함하는 조성물의 피부염 개선 용도
KR102646145B1 (ko) * 2018-05-31 2024-03-11 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물
CN110693857B (zh) * 2019-10-17 2023-08-11 宜昌人福药业有限责任公司 一种舒芬太尼透皮贴剂及其制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE410009C (de) * 1923-12-25 1925-02-21 Willi Reiche Dipl Ing Sprungwellenschutz fuer die Induktionswicklungen elektrischer Apparate und Maschinen
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
BR8008859A (pt) * 1979-10-10 1981-08-25 Cyclotech Med Ind Bandagem bloqueadora de dor
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery

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AU2426792A (en) 1993-02-23
ZA925513B (en) 1993-08-03
GR3017333T3 (en) 1995-12-31
MX9204304A (es) 1993-01-01
IE922372A1 (en) 1993-01-27
JPH06509254A (ja) 1994-10-20
DE69204676D1 (de) 1995-10-12
ATE127340T1 (de) 1995-09-15
ES2076779T3 (es) 1995-11-01
US5203768A (en) 1993-04-20
PT100720A (pt) 1994-05-31
WO1993001807A1 (en) 1993-02-04
IE71032B1 (en) 1997-01-15
EP0596036A1 (en) 1994-05-11
DE69204676T2 (de) 1996-02-08
EP0596036B1 (en) 1995-09-06

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