DK0590551T3 - Nye terapeutiske anvendelser af phthalazinonderivater - Google Patents

Nye terapeutiske anvendelser af phthalazinonderivater

Info

Publication number
DK0590551T3
DK0590551T3 DK93115512.1T DK93115512T DK0590551T3 DK 0590551 T3 DK0590551 T3 DK 0590551T3 DK 93115512 T DK93115512 T DK 93115512T DK 0590551 T3 DK0590551 T3 DK 0590551T3
Authority
DK
Denmark
Prior art keywords
therapeutic applications
new therapeutic
phthalazine derivatives
derivatives
control
Prior art date
Application number
DK93115512.1T
Other languages
Danish (da)
English (en)
Inventor
Juergen Prof Engel
Bernhard Dr Kutscher
Ilona Dr Fleischhauer
Stefan Prof Szelenyi
Peter Dr Metzenauer
Ulrich Dr Werner
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Application granted granted Critical
Publication of DK0590551T3 publication Critical patent/DK0590551T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK93115512.1T 1992-10-02 1993-09-25 Nye terapeutiske anvendelser af phthalazinonderivater DK0590551T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4233113 1992-10-02

Publications (1)

Publication Number Publication Date
DK0590551T3 true DK0590551T3 (da) 1997-04-21

Family

ID=6469448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93115512.1T DK0590551T3 (da) 1992-10-02 1993-09-25 Nye terapeutiske anvendelser af phthalazinonderivater

Country Status (18)

Country Link
US (1) US5556856A (enExample)
EP (1) EP0590551B1 (enExample)
JP (1) JP3623975B2 (enExample)
CN (1) CN1088435A (enExample)
AT (1) ATE144708T1 (enExample)
AU (1) AU666773B2 (enExample)
CA (1) CA2107548A1 (enExample)
CZ (1) CZ199593A3 (enExample)
DE (1) DE59304351D1 (enExample)
DK (1) DK0590551T3 (enExample)
ES (1) ES2096168T3 (enExample)
GR (1) GR3022070T3 (enExample)
HU (1) HUT65353A (enExample)
MX (1) MX9306120A (enExample)
RU (1) RU2106143C1 (enExample)
SK (1) SK104493A3 (enExample)
UA (1) UA26953C2 (enExample)
ZA (1) ZA937315B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162616A (en) * 1997-04-16 2000-12-19 Millennium Pharmaceuticals, Inc. Multidrug resistance-associated polypeptide
US7151102B2 (en) 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
CA2465886A1 (en) * 2001-11-07 2003-05-15 Kathleen S. Crowley Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
ES2357057T3 (es) 2002-04-30 2011-04-15 Kudos Pharmaceuticals Limited Derivados de ftalazinona.
GB0305681D0 (en) 2003-03-12 2003-04-16 Kudos Pharm Ltd Phthalazinone derivatives
US7449464B2 (en) 2003-03-12 2008-11-11 Kudos Pharmaceuticals Limited Phthalazinone derivatives
US7294701B2 (en) * 2003-04-02 2007-11-13 Technion Research & Development Foundation Ltd. Antibody fragment capable of modulating multidrug resistance and compositions and kits and methods using same
GB0419072D0 (en) 2004-08-26 2004-09-29 Kudos Pharm Ltd Phthalazinone derivatives
GB0428111D0 (en) * 2004-12-22 2005-01-26 Kudos Pharm Ltd Pthalazinone derivatives
GB0521373D0 (en) 2005-10-20 2005-11-30 Kudos Pharm Ltd Pthalazinone derivatives
KR20090007604A (ko) * 2006-04-20 2009-01-19 글락소 그룹 리미티드 히스타민 ｈ１ 및 ｈ３ 길항제로서의 2―치환된 4―벤질프탈라지논 유도체
US20090281086A1 (en) * 2006-06-15 2009-11-12 Kudos Pharmaceuticals Limited 2 -oxyheteroarylamide derivatives as parp inhibitors
WO2007144652A2 (en) * 2006-06-15 2007-12-21 Kudos Pharmaceuticals Limited Parp inhibitors
WO2007144639A1 (en) * 2006-06-15 2007-12-21 Kudos Pharmaceuticals Limited 2 -oxybenzamide derivatives as parp inhibitors
UY30639A1 (es) 2006-10-17 2008-05-31 Kudos Pharm Ltd Derivados sustituidos de 2h-ftalazin-1-ona, sus formas cristalinas, proceso de preparacion y aplicaciones
DE602007005167D1 (de) * 2006-12-20 2010-04-15 Glaxo Group Ltd 4-benzyl-1(2h)-phthalazinone als h1-rezeptor-antagonisten
US20080280910A1 (en) * 2007-03-22 2008-11-13 Keith Allan Menear Phthalazinone derivatives
TW200900396A (en) * 2007-04-10 2009-01-01 Kudos Pharm Ltd Phthalazinone derivatives
US20090023727A1 (en) * 2007-07-05 2009-01-22 Muhammad Hashim Javaid Phthalazinone derivatives
US7981890B2 (en) 2007-09-14 2011-07-19 Astrazeneca Ab Phthalazinone derivatives
ATE525370T1 (de) * 2007-10-11 2011-10-15 Glaxo Group Ltd Phthalazin- und pyridoä3,4- düpyridazinverbindungen als h1-rezeptor- antagonisten
EP2212296B1 (en) 2007-10-17 2014-12-03 Kudos Pharmaceuticals Limited 4- [3- (4-cyclopropanecarbonyl-piperazine-i-carbonyl) -4 -fluoro-benzyl]-2h-phthalaz in-1-one
UY31603A1 (es) 2008-01-23 2009-08-31 Derivados de ftalazinona
MY160340A (en) 2008-10-07 2017-02-28 Astrazeneca Uk Ltd Pharmaceutical formulation 514
TW201114756A (en) * 2009-07-15 2011-05-01 Astrazeneca Ab Phthalazinone compound
WO2014160440A1 (en) 2013-03-13 2014-10-02 Flatley Discovery Lab Pyridazinone compounds and methods for the treatment of cystic fibrosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60598T1 (de) * 1985-11-11 1991-02-15 Asta Pharma Ag 4-benzyl-1-(2h)-phthalazinon-derivate.
JPH0667844B2 (ja) * 1987-03-06 1994-08-31 エーザイ株式会社 虚血性心疾患の治療・予防剤
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis

Also Published As

Publication number Publication date
GR3022070T3 (en) 1997-03-31
SK104493A3 (en) 1994-08-10
ATE144708T1 (de) 1996-11-15
AU666773B2 (en) 1996-02-22
HUT65353A (en) 1994-05-02
ES2096168T3 (es) 1997-03-01
UA26953C2 (uk) 1999-12-29
DE59304351D1 (de) 1996-12-05
EP0590551A2 (de) 1994-04-06
US5556856A (en) 1996-09-17
JPH06312928A (ja) 1994-11-08
JP3623975B2 (ja) 2005-02-23
CZ199593A3 (en) 1994-04-13
HU9302784D0 (en) 1993-12-28
EP0590551B1 (de) 1996-10-30
CN1088435A (zh) 1994-06-29
MX9306120A (es) 1994-04-29
CA2107548A1 (en) 1994-04-03
AU4876993A (en) 1994-04-14
ZA937315B (en) 1994-04-22
EP0590551A3 (enExample) 1994-08-31
RU2106143C1 (ru) 1998-03-10

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