DK0588875T3 - Mikrosfærer, som er anvendelige til terapeutiske vaskulære okklusioner, og injicerbare opløsninger indeholdende disse mikrosfærer - Google Patents

Mikrosfærer, som er anvendelige til terapeutiske vaskulære okklusioner, og injicerbare opløsninger indeholdende disse mikrosfærer

Info

Publication number
DK0588875T3
DK0588875T3 DK92911942.8T DK92911942T DK0588875T3 DK 0588875 T3 DK0588875 T3 DK 0588875T3 DK 92911942 T DK92911942 T DK 92911942T DK 0588875 T3 DK0588875 T3 DK 0588875T3
Authority
DK
Denmark
Prior art keywords
microspheres
injectable solutions
solutions containing
useful
vascular occlusions
Prior art date
Application number
DK92911942.8T
Other languages
Danish (da)
English (en)
Inventor
Egisto Boschetti
Michel Brouard
Ludovic Drouet
Pierre Girot
Alexandre Laurent
Michel Wasser
Original Assignee
Lassistance Publique Hopitaux
Biosepra Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lassistance Publique Hopitaux, Biosepra Sa filed Critical Lassistance Publique Hopitaux
Application granted granted Critical
Publication of DK0588875T3 publication Critical patent/DK0588875T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92911942.8T 1991-05-29 1992-05-20 Mikrosfærer, som er anvendelige til terapeutiske vaskulære okklusioner, og injicerbare opløsninger indeholdende disse mikrosfærer DK0588875T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9106441A FR2676927B1 (fr) 1991-05-29 1991-05-29 Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant.

Publications (1)

Publication Number Publication Date
DK0588875T3 true DK0588875T3 (da) 1997-04-28

Family

ID=9413226

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92911942.8T DK0588875T3 (da) 1991-05-29 1992-05-20 Mikrosfærer, som er anvendelige til terapeutiske vaskulære okklusioner, og injicerbare opløsninger indeholdende disse mikrosfærer

Country Status (11)

Country Link
US (2) US5635215A (es)
EP (1) EP0588875B1 (es)
JP (1) JP3509858B2 (es)
AT (1) ATE151284T1 (es)
AU (1) AU661319B2 (es)
CA (1) CA2110290C (es)
DE (1) DE69218938T2 (es)
DK (1) DK0588875T3 (es)
ES (1) ES2099827T3 (es)
FR (1) FR2676927B1 (es)
WO (1) WO1992021327A1 (es)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4341478C2 (de) * 1993-12-02 1998-10-08 Max Delbrueck Centrum Mittel zur Antitumortherapie
US6197324B1 (en) 1997-12-18 2001-03-06 C. R. Bard, Inc. System and methods for local delivery of an agent
US6251418B1 (en) * 1997-12-18 2001-06-26 C.R. Bard, Inc. Systems and methods for local delivery of an agent
WO1999044643A1 (en) * 1998-03-06 1999-09-10 Biosepra Medical Inc. Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles
EP1522317A1 (en) * 1998-03-06 2005-04-13 Biosphere Medical, Inc. Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles
US6660301B1 (en) * 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
FR2784580B1 (fr) 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
DK1163019T3 (da) * 1999-03-25 2008-03-03 Metabolix Inc Medicinske indretninger og anvendelser af polyhydroxyalkanoatpolymere
US20050049178A1 (en) * 1999-07-06 2005-03-03 Oberschwabenklinik Gmbh Agent for the occlusion of blood vessels
DE29911689U1 (de) * 1999-07-06 2000-04-06 Sterk, Peter, Dr., 88212 Ravensburg Mittel für den Gefässverschluß von organischem Gewebe
US6855160B1 (en) 1999-08-04 2005-02-15 C. R. Bard, Inc. Implant and agent delivery device
JP4871476B2 (ja) 2000-03-13 2012-02-08 バイオコンパティブルズ ユーケー リミテッド 塞栓組成物
ATE327262T1 (de) 2000-03-13 2006-06-15 Biocure Inc Zusammensetzungen zur erhöhung des gewebevolumens und beschichtungszusammensetzungen
EP1656957B1 (en) 2000-03-20 2015-06-03 Biosphere Medical, Inc. Injectable microspheres for tissue construction
AU2001249221A1 (en) * 2000-03-20 2001-10-03 Biosphere Medical, Inc. Injectable and swellable microspheres for tissue bulking
US6436424B1 (en) 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
WO2001070290A2 (en) * 2000-03-20 2001-09-27 Biosphere Medical, Inc. Injectable microspheres for tissue construction
US7338657B2 (en) * 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
ES2254042T3 (es) 2000-03-24 2008-03-16 Biosphere Medical, Inc. Microesferas para embolizacion activa.
AU2001245987A1 (en) * 2000-03-24 2001-10-08 Biosphere Medical, Inc. Compositions and methods for gene therapy
US20030212022A1 (en) * 2001-03-23 2003-11-13 Jean-Marie Vogel Compositions and methods for gene therapy
US7232421B1 (en) 2000-05-12 2007-06-19 C. R. Bard, Inc. Agent delivery systems
US6355275B1 (en) 2000-06-23 2002-03-12 Carbon Medical Technologies, Inc. Embolization using carbon coated microparticles
US6394965B1 (en) 2000-08-15 2002-05-28 Carbon Medical Technologies, Inc. Tissue marking using biocompatible microparticles
FR2816847B1 (fr) * 2000-11-22 2006-07-14 Assist Publ Hopitaux De Paris Biomateriaux polymeriques poreux, procede de preparation et utilisations
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
WO2002100444A1 (en) * 2001-06-08 2002-12-19 Biosphere Medical Inc. Colloidal metal labelled microparticles, their production and use
ATE400250T1 (de) 2001-09-12 2008-07-15 Virexx Medical Corp Festphasenmittel zur vaskulären okklusion mit immobilisierter thrombozyten-bindungssubstanz
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7276254B2 (en) * 2002-05-07 2007-10-02 Xerox Corporation Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same
US7838699B2 (en) * 2002-05-08 2010-11-23 Biosphere Medical Embolization using degradable crosslinked hydrogels
US7670623B2 (en) * 2002-05-31 2010-03-02 Materials Modification, Inc. Hemostatic composition
WO2003105917A2 (en) 2002-06-12 2003-12-24 Scimed Life Systems, Inc. Bulking agents
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US20040168245A1 (en) * 2002-10-18 2004-09-02 Goodwin Edward L. Washable, protective hip pad construction
US7112620B2 (en) * 2002-10-18 2006-09-26 Albright Robert L Hemocompatible polymer systems & related methods
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
EP1559440B1 (en) * 2002-10-29 2015-09-23 Toray Industries, Inc. Vascular embolization meterial
JP4686970B2 (ja) * 2002-10-29 2011-05-25 東レ株式会社 血管塞栓材料
EP1578455A4 (en) * 2002-11-04 2008-12-31 Biosphere Medical Inc POLYMER HYDROGEL MICROSPHERES ASSOCIATED WITH RADIOISOTOPES AND METHODS OF MAKING AND USING THE SAME
US7560160B2 (en) * 2002-11-25 2009-07-14 Materials Modification, Inc. Multifunctional particulate material, fluid, and composition
US7007972B1 (en) 2003-03-10 2006-03-07 Materials Modification, Inc. Method and airbag inflation apparatus employing magnetic fluid
JP2004313759A (ja) * 2003-03-31 2004-11-11 Toray Ind Inc 血管塞栓材料
JP2007525601A (ja) 2003-05-08 2007-09-06 テファ， インコーポレイテッド ポリヒドロキシアルカノエート医療用織物および医療用繊維
US6982501B1 (en) 2003-05-19 2006-01-03 Materials Modification, Inc. Magnetic fluid power generator device and method for generating power
CA2531833C (en) * 2003-07-08 2009-10-20 Tepha, Inc. Poly-4-hydroxybutyrate matrices for sustained drug delivery
US7200956B1 (en) 2003-07-23 2007-04-10 Materials Modification, Inc. Magnetic fluid cushioning device for a footwear or shoe
US20060287659A1 (en) * 2003-08-22 2006-12-21 Tepha, Inc. Polyhydroxyalkanoate nerve regeneration devices
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7448389B1 (en) 2003-10-10 2008-11-11 Materials Modification, Inc. Method and kit for inducing hypoxia in tumors through the use of a magnetic fluid
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US8080577B2 (en) * 2004-05-06 2011-12-20 Bioresponse, L.L.C. Diindolylmethane formulations for the treatment of leiomyomas
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
DK1778305T3 (da) * 2004-08-03 2010-10-18 Tepha Inc Ikke-krøllende polyhydroxyalkanoatsuturer
AU2005290229A1 (en) * 2004-09-24 2006-04-06 Biosphere Medical, Inc. Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof
US20060073208A1 (en) * 2004-10-01 2006-04-06 Allergan, Inc. Cosmetic neurotoxin compositions and methods
JP4885866B2 (ja) 2004-10-25 2012-02-29 セロノヴァ バイオサイエンスィズ ジャーマニー ゲーエムベーハー 治療適用および／または診断適用のための充填可能なポリホスファゼン含有粒子、ならびにその調製方法および使用方法
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
ATE497762T1 (de) 2004-12-30 2011-02-15 Bioresponse Llc Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus
WO2006078841A1 (en) * 2005-01-21 2006-07-27 President And Fellows Of Harvard College Systems and methods for forming fluidic droplets encapsulated in particles such as colloidal particles
WO2006081517A2 (en) * 2005-01-28 2006-08-03 Tepha, Inc. Embolization using poly-4-hydroxybutyrate particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
CN101237857A (zh) 2005-05-09 2008-08-06 生物领域医疗公司 使用微球和非离子型造影剂的组合物和方法
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US20080033366A1 (en) * 2006-01-30 2008-02-07 Surgica Corporation Compressible intravascular embolization particles and related methods and delivery systems
EP2368581B1 (en) * 2006-01-30 2018-08-29 Biosphere Medical, Inc. Porous intravascular embolization particles and related methods
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
WO2008057253A2 (en) 2006-10-27 2008-05-15 Bioresponse, L.L.C. Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US7943683B2 (en) * 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
WO2008134580A2 (en) * 2007-04-27 2008-11-06 Amylin Pharmaceuticals, Inc. Drug delivery device
EP2222349B1 (en) * 2007-12-17 2014-03-12 Anna Love Soft tissue filler
JP2012507562A (ja) * 2008-10-30 2012-03-29 ダビド リウ 微小球性多孔質生体適合性足場並びにその製造方法及び装置
US20120009242A1 (en) * 2008-11-03 2012-01-12 University Of Maryland, College Park Blood coagulation inducing polymer hydrogel
CN104307036A (zh) 2009-10-06 2015-01-28 明尼苏达大学董事会 一种微球形式的栓塞材料及其制备方法与栓塞悬浮液
EP2351779B1 (en) * 2010-01-27 2019-04-24 Biosphere Medical, Inc. Microspheres and method of making the microspheres
EP2692368B1 (en) * 2011-03-30 2018-02-21 Toray Industries, Inc. Biodegradable particle, vascular embolization material and method for producing biodegradable particles
EP3295961B1 (en) * 2012-05-24 2020-04-08 Biosphere Medical Inc. Biomaterials suitable for use as drug eluting, magnetic resonance imaging detectable implants for vascular occlusion
US8936795B2 (en) 2012-12-19 2015-01-20 Regents Of The University Of Minnesota Liquid embolic material including carboxymethyl chitosan crosslinked with carboxymethyl cellulose
JP6373961B2 (ja) 2013-03-13 2018-08-15 バイオスフィア メディカル，インコーポレイテッド ラジオアイソトープ結合微粒子の組成物及び結合方法
WO2015042170A1 (en) 2013-09-17 2015-03-26 Wayne State University Compositions and uses of combinations of dim-related indoles and selected anti-androgen compounds
US9408916B2 (en) 2013-09-19 2016-08-09 Microvention, Inc. Polymer films
WO2015042461A1 (en) 2013-09-19 2015-03-26 Microvention, Inc. Polymer particles
CA2929235C (en) 2013-11-08 2018-07-17 Terumo Corporation Polymer particles
CA2958747C (en) 2014-08-15 2022-08-16 Tepha, Inc. Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof
WO2016094669A1 (en) 2014-12-11 2016-06-16 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
EP4245782A1 (en) * 2015-01-12 2023-09-20 Biosphere Medical, Inc. Radiopaque monomers, polymers, microspheres, and methods related thereto
WO2016154592A1 (en) 2015-03-26 2016-09-29 Microvention, Inc. Embiolic particles
US10071181B1 (en) 2015-04-17 2018-09-11 Teleflex Innovations S.À.R.L. Resorbable embolization spheres
CN115137870B (zh) 2016-03-14 2024-05-10 生物相容性英国公司 包含颗粒的乳液
US10182979B2 (en) 2016-03-22 2019-01-22 Regents Of The University Of Minnesota Biodegradable microspheres
WO2018064390A1 (en) 2016-09-28 2018-04-05 Microvention, Inc. Polymer particles
WO2021069527A1 (fr) * 2019-10-07 2021-04-15 Guerbet Microsphere d'embolisation non degradable
US20230285601A1 (en) * 2019-10-07 2023-09-14 Guerbet Non degradable radio-opaque embolisation microsphere

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797485A (en) * 1971-03-26 1974-03-19 Alza Corp Novel drug delivery device for administering drug into blood circulation in blood vessel
US4622362A (en) * 1981-03-30 1986-11-11 California Institute Of Technology Polyacrolein microspheres
US4413070A (en) * 1981-03-30 1983-11-01 California Institute Of Technology Polyacrolein microspheres
DE3360633D1 (en) * 1982-02-12 1985-10-03 Unitika Ltd Anti-cancer device
JPS61293911A (ja) * 1985-06-24 1986-12-24 Teisan Seiyaku Kk 徐放化製剤
JPS62169723A (ja) * 1986-01-22 1987-07-25 Teisan Seiyaku Kk 徐放化製剤

Also Published As

Publication number Publication date
AU661319B2 (en) 1995-07-20
FR2676927B1 (fr) 1995-06-23
US5648100A (en) 1997-07-15
EP0588875B1 (en) 1997-04-09
US5635215A (en) 1997-06-03
CA2110290C (en) 2002-02-05
JP3509858B2 (ja) 2004-03-22
WO1992021327A1 (en) 1992-12-10
EP0588875A1 (en) 1994-03-30
DE69218938T2 (de) 1997-07-31
DE69218938D1 (de) 1997-05-15
FR2676927A1 (fr) 1992-12-04
CA2110290A1 (en) 1992-12-10
ES2099827T3 (es) 1997-06-01
EP0588875A4 (es) 1994-08-03
AU2016892A (en) 1993-01-08
ATE151284T1 (de) 1997-04-15
JPH06508139A (ja) 1994-09-14

Similar Documents

Publication Publication Date Title
DK0588875T3 (da) Mikrosfærer, som er anvendelige til terapeutiske vaskulære okklusioner, og injicerbare opløsninger indeholdende disse mikrosfærer
ES8607355A1 (es) Una composicion adhesiva
EP0655259A3 (en) Vascular blood retention device.
NO900990D0 (no) Systemer for lagring og utlevering av gass.
EP0673229A4 (en) SURGICAL LIGATION CLIP.
MX9203755A (es) Dispositivo de suministro iontoforetico de drogas o agentes terapeuticos, dotado de un adhesivo de electrotransporte.
DE69012888D1 (de) Plasminogenaktivator.
NO20100442L (no) Copolymer 1 relaterte polypeptider for anvendelse som molekylvekt markorer og for terapeutisk anvendelse
EP0601793A3 (en) One-component polyurethane adhesive and its use.
EP0648492A3 (en) Inhibition of phosphatidylinositol-3-kinase with viridin, dimethoxyviridin, viridiol, dimethoxyviridiol, virone, wortmannolone, and their derivatives.
DE68910875D1 (de) Adhäsive oder kohäsive, elastomerische Materialien.
FI891438A0 (fi) Foerfarande foer framstaellning av farmaceutiska sammansaettningar som inverkar i synnerhet pao det kardiovaskulaera systemet.
DE58903654D1 (de) Elastisches lager.
ES2139931T3 (es) Adhesivo de contacto de uso medico.
FR2675346B1 (fr) Boisson contenant un agent antimousse.
IT1255981B (it) Composizione adesiva a piu' componenti
DE3882165D1 (de) Linearer feuerloescher.
FI880960A (fi) Anvaendning av rnas l inhibitor som markeringsaemne i virusinfektioner.
IE892630L (en) Novel combination
FI883943A (fi) Modifierade plasminogen-aktivatorer.
AU4277489A (en) Automatic sprinkler activator
ES1008874U (es) Perfil de apoyo de goma para objetos de adorno de vidrio y similares.
EP0364587A4 (en) HEXAFLUORONEOPENTYL ALCOHOL, ITS DERIVATIVES, FLUORINATED POLYMERS AND THEIR USE.
NO883302D0 (no) Fortoeyningssystem, progressivt elastisk, for fartoeyer og andre objekter.
FR2712797B1 (fr) Système d'occlusion vasculaire.