ATE497762T1 - Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus - Google Patents
Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virusInfo
- Publication number
- ATE497762T1 ATE497762T1 AT05857257T AT05857257T ATE497762T1 AT E497762 T1 ATE497762 T1 AT E497762T1 AT 05857257 T AT05857257 T AT 05857257T AT 05857257 T AT05857257 T AT 05857257T AT E497762 T1 ATE497762 T1 AT E497762T1
- Authority
- AT
- Austria
- Prior art keywords
- diindolylmethane
- prevention
- treatment
- rsv
- syncytial virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64030104P | 2004-12-30 | 2004-12-30 | |
PCT/US2005/047537 WO2006083458A2 (en) | 2004-12-30 | 2005-12-30 | Use of diindolylmethane-related indoles for the treatment and prevention of respiratory syncytial virus associates conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE497762T1 true ATE497762T1 (de) | 2011-02-15 |
Family
ID=36777712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05857257T ATE497762T1 (de) | 2004-12-30 | 2005-12-30 | Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus |
Country Status (6)
Country | Link |
---|---|
US (2) | US7989486B2 (de) |
EP (1) | EP1838303B1 (de) |
AT (1) | ATE497762T1 (de) |
CA (1) | CA2593084C (de) |
DE (1) | DE602005026328D1 (de) |
WO (1) | WO2006083458A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
BRPI0511834A (pt) | 2004-07-14 | 2008-01-08 | Ptc Therapeutics Inc | métodos por tratar hepatite c |
DE602005026328D1 (de) * | 2004-12-30 | 2011-03-24 | Bioresponse Llc | Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus |
US20070059310A1 (en) * | 2005-05-03 | 2007-03-15 | Karel Steven J | Therapeutic combination compositions and methods of using same |
WO2007016935A1 (en) * | 2005-07-29 | 2007-02-15 | Histogenex Nv | Methods, reagents and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies |
BRPI0717753B1 (pt) | 2006-10-27 | 2022-04-12 | Bioresponse, Llc | Uso de uma composição compreendendo 50-250 mg de um ou mais indóis relacionados com dim e um ou mais agentes anti-protozoários, e, composição |
WO2009103755A1 (en) * | 2008-02-19 | 2009-08-27 | Dsm Ip Assets B.V. | Novel use of 3,3'-diindolylmethane |
WO2010026029A1 (en) * | 2008-09-03 | 2010-03-11 | Boehringer Ingelheim International Gmbh | Use of quinazoline derivatives for the treatment of viral diseases |
JP5550151B2 (ja) | 2008-09-17 | 2014-07-16 | エスアールアイ インターナショナル | インドール−3−カルビノール類似体およびその感染に対する薬剤としての使用 |
AU2009344851A1 (en) * | 2008-12-19 | 2011-06-23 | The Regents Of The University Of California | Use of epidermal growth factor inhibitors in the treatment of viral infection |
CN101428016B (zh) * | 2008-12-23 | 2011-06-15 | 南京大学 | 二吲哚甲烷及其衍生物在制备治疗类风湿关节炎的药物中的应用 |
WO2010118339A2 (en) * | 2009-04-09 | 2010-10-14 | University Of Kansas | Formulations of indole-3-carbinol derived antitumor agents with increased oral bioavailability |
GB201004761D0 (en) * | 2010-03-22 | 2010-05-05 | Medical Res Council | Method |
CN102133210A (zh) * | 2010-04-28 | 2011-07-27 | 重庆医科大学附属儿童医院 | 白藜芦醇在制备预防和治疗呼吸道合胞病毒感染的药物中的应用 |
KR20130091761A (ko) * | 2010-08-18 | 2013-08-19 | 클레어파르마 인더스트리즈 리미티드. | 기능성 식품 조성물 및 그 제조방법 |
GB201105050D0 (en) | 2011-03-25 | 2011-05-11 | Iiaa Ltd | Pharmaceutical agent |
CA2827214C (en) | 2011-04-01 | 2017-07-18 | Sri International | Lipoxygenase inhibitors |
US20150297593A1 (en) * | 2012-09-14 | 2015-10-22 | Children's Medical Center Corporation | Inhibition of viral infection-triggered asthma with c-kit inhibitor |
CN105272900B (zh) * | 2015-01-21 | 2018-06-19 | 南通大学 | 双吲哚类衍生物及其制备方法与应用 |
WO2016164770A1 (en) | 2015-04-10 | 2016-10-13 | Bioresponse, L.L.C. | Self-emulsifying formulations of dim-related indoles |
CN105030766A (zh) * | 2015-06-24 | 2015-11-11 | 安徽四正医药科技有限公司 | 吲哚-3-甲醇、二吲哚甲烷及其衍生物用于治疗过敏性咽炎药物的应用 |
WO2017001979A1 (en) * | 2015-06-27 | 2017-01-05 | Reform Bio Inc. | Diindolyl methane compositions, formulations and use thereof |
CN110074978A (zh) * | 2019-03-13 | 2019-08-02 | 安庆瑄宇医药科技有限公司 | 一种缬更昔洛韦组合片剂及其制备方法 |
RU2740377C1 (ru) * | 2020-03-18 | 2021-01-13 | Всеволод Иванович Киселёв | Способ лечения эндометриоза и сопутствующего спаечного процесса лекарственным средством на основе 3,3'-дииндолилметана в комплексе с B-циклодекстрином |
CA3179635A1 (en) | 2020-05-29 | 2021-12-02 | Boulder Bioscience Llc | Methods for improved endovascular thrombectomy using 3,3'-diindolylmethane |
CN116585321B (zh) * | 2023-02-21 | 2024-04-26 | 华中科技大学同济医学院附属协和医院 | 更昔洛韦在制备治疗过敏性鼻炎药物中的应用 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5718921A (en) | 1987-03-13 | 1998-02-17 | Massachusetts Institute Of Technology | Microspheres comprising polymer and drug dispersed there within |
FR2676927B1 (fr) | 1991-05-29 | 1995-06-23 | Ibf | Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant. |
AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
DK0656786T3 (da) | 1992-05-19 | 2004-11-08 | Novogen Res Pty Ltd | Anvendelse af isoflavonphytoöstrogenekstrakter af soja eller klöver |
CA2216796C (en) | 1995-03-30 | 2003-09-02 | Pfizer Inc. | Quinazoline derivatives |
GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
KR100437582B1 (ko) | 1995-07-06 | 2004-12-17 | 노파르티스 아게 | 피롤로피리미딘및그들의제조방법 |
US6127393A (en) | 1995-12-29 | 2000-10-03 | Novactyl, Inc. | Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method |
US5767135A (en) | 1995-12-29 | 1998-06-16 | Fernandez-Pol; Jose Alberto | Antiviral agent |
GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
CA2249446C (en) | 1996-04-12 | 2008-06-17 | Warner-Lambert Company | Irreversible inhibitors of tyrosine kinases |
US5948808A (en) | 1997-03-07 | 1999-09-07 | The Texas A&M University System | Indole-3-carbinol, diindolylmethane and substituted analogs as antiestrogens |
CA2284039A1 (en) | 1997-03-18 | 1998-09-24 | Ortho-Mcneil Pharmaceutical, Inc. | Methods and kits for treating and diagnosing leiomyomas |
US6083932A (en) | 1997-04-18 | 2000-07-04 | Cv Technologies Inc. | Pharmaceutical compositions derived from ginseng and methods of treatment using same |
US6001868A (en) | 1997-05-30 | 1999-12-14 | The Regents Of The University Of California | Indole-3-carbinol (I3C) derivatives and methods |
US6150395A (en) | 1997-05-30 | 2000-11-21 | The Regents Of The University Of California | Indole-3-carbinol (I3C) derivatives and methods |
US5895787A (en) | 1997-10-08 | 1999-04-20 | Designed Nutritional Products, Inc. | Treatment of fibromyalgia and related disorders |
US6086915A (en) * | 1998-04-01 | 2000-07-11 | Bioresponse L.L.C. | Compositions and methods of adjusting steroid hormone metabolism through phytochemicals |
ATE295839T1 (de) | 1998-04-29 | 2005-06-15 | Osi Pharm Inc | N-(3-ethinylphenylamino)-6,7-bis(2-methoxyethox )-4-chinazolinamin-mesylat-anhydrat und -monohydrat |
WO2000002857A1 (en) | 1998-07-08 | 2000-01-20 | Harbor Branch Oceanographic Institution, Inc. | Bis-indole derivatives and their use as antiinflammatory agents |
PT1131304E (pt) | 1998-11-19 | 2003-04-30 | Warner Lambert Co | N-¬4-(3-cloro-4-fluoro-fenilamino)-7-(3-morfolin-4-il-propoxi)-quinazolin-6-il|-acrilamida um inibidor irreversivel de tirosino quinases |
US6613792B1 (en) | 1999-08-02 | 2003-09-02 | Designed Nutritional Products, Inc. | Treatment of premenstrual syndrome and menopause |
US6534085B1 (en) | 1999-09-23 | 2003-03-18 | Bioresponse L.L.C. | Phytochemicals for promoting weight loss |
US7384971B2 (en) | 1999-09-23 | 2008-06-10 | Bioresponse L.L.C. | Phytochemicals for the treatment of cervical dysplasia |
US6689387B1 (en) | 1999-09-23 | 2004-02-10 | Bioresponse Llc | Phytochemicals for treatment of mastalgia and endometriosis |
AU775459B2 (en) | 1999-10-04 | 2004-08-05 | Lawrence R. Bernstein | Gallium complexes of 3-hydroxy-4-pyrones to treat infection by intracellular prokaryotes, DNA viruses and retroviruses |
US6676971B2 (en) | 2000-03-13 | 2004-01-13 | Biocure, Inc. | Embolic compositions |
US6399645B1 (en) | 2000-03-20 | 2002-06-04 | Maria Bell | Chemoprevention and treatment of cervical or vaginal neoplasia |
CN1430505A (zh) | 2000-03-24 | 2003-07-16 | 生物领域医疗公司 | 用于主动栓塞术的微球体 |
US6477229B1 (en) | 2000-05-12 | 2002-11-05 | Siemens Medical Solutions Usa, Inc. | Radiation therapy planning |
US6416793B1 (en) | 2000-07-11 | 2002-07-09 | Bioresponse, L.L.C. | Formulations and use of controlled-release indole alkaloids |
US7709520B2 (en) | 2000-10-06 | 2010-05-04 | The Texas A&M University System | Diindolylmethane and C-substituted diindolylmethane compositions and methods for the treatment of multiple cancers |
US6468557B1 (en) | 2001-01-05 | 2002-10-22 | Alphamed Pharmaceutical Corp. | Method for treating infectious viral diseases |
US20020147155A1 (en) | 2001-04-06 | 2002-10-10 | Foster Warren G. | Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands |
US7030150B2 (en) * | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
EP1269994A3 (de) | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmazeutische Zusammensetzungen die ein Arzneimittel und die Konzentration verbesserende Polymere enthalten |
US7348352B2 (en) | 2001-10-23 | 2008-03-25 | Bioresponse L.L.C. | Diindolylmethane for the treatment of HPV infection |
US6544564B1 (en) * | 2001-11-27 | 2003-04-08 | Michael Donald Farley | Cytotoxic pharmaceutical composition |
TW200408407A (en) * | 2001-11-30 | 2004-06-01 | Dana Farber Cancer Inst Inc | Methods and compositions for modulating the immune system and uses thereof |
US20030220377A1 (en) | 2002-05-08 | 2003-11-27 | Richard Chesworth | Indole compounds and their use as estrogen agonists/antagonists |
US6800655B2 (en) | 2002-08-20 | 2004-10-05 | Sri International | Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents |
ES2391770T3 (es) * | 2003-01-21 | 2012-11-29 | Novartis Vaccines And Diagnostics, Inc. | Uso de compuestos de triptantrina para la potenciación inmune |
EP1601367A2 (de) | 2003-02-06 | 2005-12-07 | Bioresponse L.L.C. | Kombinierte benutzung von kreuzblütler-indolen und chelatbildenden mitteln zur behandlung von durch den papillomavirus bedingten zuständen |
US20040235931A1 (en) * | 2003-04-17 | 2004-11-25 | John Docherty | Inhibition of herpes virus replication |
US20050123560A1 (en) * | 2003-12-04 | 2005-06-09 | Sinnott Robert A. | High purity and water dispersible extract and formulations of larrea tridentata leaf resin, and methods of making and using the same |
US8080577B2 (en) | 2004-05-06 | 2011-12-20 | Bioresponse, L.L.C. | Diindolylmethane formulations for the treatment of leiomyomas |
WO2006047716A2 (en) * | 2004-10-26 | 2006-05-04 | Bioresponse Llc | Use of diindolylmethane-related indoles and growth factor receptor inhibitors for the treatment of human cytomegalovirus associated disease |
US20060100264A1 (en) * | 2004-11-06 | 2006-05-11 | Bjeldanes Leonard F | 3,3'-Diindolylmethane immune activating compositions |
DE602005026328D1 (de) | 2004-12-30 | 2011-03-24 | Bioresponse Llc | Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus |
US20060229355A1 (en) | 2005-04-08 | 2006-10-12 | The Regents Of The University Of California | 3.3'-Diindolylmethane compositions inhibit angiogenesis |
-
2005
- 2005-12-30 DE DE602005026328T patent/DE602005026328D1/de active Active
- 2005-12-30 AT AT05857257T patent/ATE497762T1/de not_active IP Right Cessation
- 2005-12-30 EP EP05857257A patent/EP1838303B1/de not_active Not-in-force
- 2005-12-30 WO PCT/US2005/047537 patent/WO2006083458A2/en active Application Filing
- 2005-12-30 US US11/322,803 patent/US7989486B2/en not_active Expired - Fee Related
- 2005-12-30 CA CA2593084A patent/CA2593084C/en not_active Expired - Fee Related
-
2011
- 2011-06-20 US US13/164,488 patent/US8552052B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1838303B1 (de) | 2011-02-09 |
CA2593084C (en) | 2014-03-18 |
EP1838303A4 (de) | 2008-06-18 |
CA2593084A1 (en) | 2006-08-10 |
US8552052B2 (en) | 2013-10-08 |
WO2006083458A2 (en) | 2006-08-10 |
EP1838303A2 (de) | 2007-10-03 |
US20080103114A1 (en) | 2008-05-01 |
WO2006083458A3 (en) | 2007-10-04 |
US20110250267A1 (en) | 2011-10-13 |
US7989486B2 (en) | 2011-08-02 |
DE602005026328D1 (de) | 2011-03-24 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |